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Volumn 35, Issue 4, 2012, Pages 1500-1506

Bacterial cell wall constituents induce hepcidin expression in macrophages through myD88 signaling

Author keywords

Hepcidin; Hypoferremia; Inflammation; Iron; Macrophages; MyD88; TLR

Indexed keywords

HEPCIDIN; INTERLEUKIN 6; IRON; LIPOPOLYSACCHARIDE; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4;

EID: 84866741440     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-012-9463-4     Document Type: Article
Times cited : (37)

References (35)
  • 2
    • 79959965423 scopus 로고    scopus 로고
    • War-fe-re: Iron at the core of fungal virulence and host immunity
    • T. Nevitt, War-Fe-re: iron at the core of fungal virulence and host immunity. Biometals 24: 547-58.
    • Biometals , vol.24 , pp. 547-558
    • Nevitt, T.1
  • 3
    • 50549098260 scopus 로고    scopus 로고
    • Withholding iron as a cellular defence mechanism-friend or foe?
    • Collins, H.L. 2008. Withholding iron as a cellular defence mechanism -friend or foe? European Journal of Immunology 38: 1803-6.
    • (2008) European Journal of Immunology , vol.38 , pp. 1803-6
    • Collins, H.L.1
  • 4
    • 70349325941 scopus 로고    scopus 로고
    • Iron sequestration and anemia of inflammation
    • Ganz, T., and E. Nemeth. 2009. Iron sequestration and anemia of inflammation. Sem Hemat 46: 387-393.
    • (2009) Sem Hemat , vol.46 , pp. 387-393
    • Ganz, T.1    Nemeth, E.2
  • 5
    • 14544298717 scopus 로고    scopus 로고
    • Hepcidin -A regulator of intestinal iron absorption and iron recycling by macrophages
    • Ganz, T. 2005. Hepcidin -A regulator of intestinal iron absorption and iron recycling by macrophages. Best Practice & Research. Clinical Haematology 18: 171-82.
    • (2005) Best Practice & Research. Clinical Haematology , vol.18 , pp. 171-82
    • Ganz, T.1
  • 6
    • 10844258104 scopus 로고    scopus 로고
    • Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
    • Nemeth, E., M.S. Tuttle, J. Powelson, M.B. Vaughn, A. Donovan, D.M. Ward, T. Ganz, and J. Kaplan. 2004. Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science 306: 2090-3.
    • (2004) Science , vol.306 , pp. 2090-3
    • Nemeth, E.1    Tuttle, M.S.2    Powelson, J.3    Vaughn, M.B.4    Donovan, A.5    Ward, D.M.6    Ganz, T.7    Kaplan, J.8
  • 14
    • 32944464648 scopus 로고    scopus 로고
    • Pathogen recognition and innate immunity
    • Akira, S., S. Uematsu, and O. Takeuchi. 2006. Pathogen recognition and innate immunity. Cell 124: 783-801.
    • (2006) Cell , vol.124 , pp. 783-801
    • Akira, S.1    Uematsu, S.2    Takeuchi, O.3
  • 15
    • 13844307889 scopus 로고    scopus 로고
    • Regulation of hepcidin transcription by interleukin-1 and interleukin-6
    • Lee, P., H. Peng, T. Gelbart, L. Wang, and E. Beutler. 2005. Regulation of hepcidin transcription by interleukin-1 and interleukin-6. Proc Natl Acad Sci USA 102: 1906-10.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 1906-10
    • Lee, P.1    Peng, H.2    Gelbart, T.3    Wang, L.4    Beutler, E.5
  • 16
    • 0034460947 scopus 로고    scopus 로고
    • The role of toll-like receptors and myd88 in innate immune responses
    • Akira, S., K. Hoshino, and T. Kaisho. 2000. The role of Toll-like receptors and MyD88 in innate immune responses. Journal of Endotoxin Research 6: 383-7.
    • (2000) Journal of Endotoxin Research , vol.6 , pp. 383-7
    • Akira, S.1    Hoshino, K.2    Kaisho, T.3
  • 17
    • 1642302853 scopus 로고    scopus 로고
    • Contributions of beta2-microglobulin-dependent molecules and lymphocytes to iron regulation: Insights from hferag1(-/-) and beta2mrag1(-/-) double knock-out mice
    • Miranda, C.J., H. Makui, N.C. Andrews, and M.M. Santos. 2004. Contributions of beta2-microglobulin-dependent molecules and lymphocytes to iron regulation: insights from HfeRag1(-/-) and beta2mRag1(-/-) double knock-out mice. Blood 103: 2847-9.
    • (2004) Blood , vol.103 , pp. 2847-9
    • Miranda, C.J.1    Makui, H.2    Andrews, N.C.3    Santos, M.M.4
  • 18
    • 79955462543 scopus 로고    scopus 로고
    • Cellular iron depletion stimulates the jnk and p38 mapk signaling transduction pathways, dissociation of ask1-Thioredoxin, and activation of ask1
    • Yu, Y., and D.R. Richardson. 2011. Cellular iron depletion stimulates the JNK and p38 MAPK signaling transduction pathways, dissociation of ASK1-Thioredoxin, and activation of ASK1. Journal of Biological Chemistry 286: 15413-15427.
    • (2011) Journal of Biological Chemistry , vol.286 , pp. 15413-15427
    • Yu, Y.1    Richardson, D.R.2
  • 19
    • 33646162871 scopus 로고    scopus 로고
    • Gene expression profiling in frataxin deficient mice: Microarray evidence for significant expression changes without detectable neurodegeneration
    • Coppola, G., S.-H. Choi, M.M. Santos, C.J. Miranda, D. Tentler, E.M. Wexler, M. Pandolfo, and D.H. Geschwind. 2006. Gene expression profiling in frataxin deficient mice: microarray evidence for significant expression changes without detectable neurodegeneration. Neurobiology of Disease 22: 302-311.
    • (2006) Neurobiology of Disease , vol.22 , pp. 302-311
    • Coppola, G.1    Choi, S.-H.2    Santos, M.M.3    Miranda, C.J.4    Tentler, D.5    Wexler, E.M.6    Pandolfo, M.7    Geschwind, D.H.8
  • 21
    • 33947531436 scopus 로고    scopus 로고
    • Repression of repulsive guidance molecule c during inflammation is independent of hfe and involves tumor necrosis factor-Alpha
    • Constante, M., D. Wang, V.A. Raymond, M. Bilodeau, and M.M. Santos. 2007. Repression of repulsive guidance molecule C during inflammation is independent of Hfe and involves tumor necrosis factor-Alpha. American Journal of Pathology 170: 497-504.
    • (2007) American Journal of Pathology , vol.170 , pp. 497-504
    • Constante, M.1    Wang, D.2    Raymond, V.A.3    Bilodeau, M.4    Santos, M.M.5
  • 22
    • 34249004485 scopus 로고    scopus 로고
    • Transcriptional regulation of lipopolysaccharide (lps)-induced toll-like receptor (tlr) expression in murine macrophages: Role of interferon regulatory factors 1 (irf-1) and 2 (irf-2
    • Nhu, Q.M., N. Cuesta, and S.N. Vogel. 2006. Transcriptional regulation of lipopolysaccharide (LPS)-induced Toll-like receptor (TLR) expression in murine macrophages: role of interferon regulatory factors 1 (IRF-1) and 2 (IRF-2). Journal of Endotoxin Research 12: 285-295.
    • (2006) Journal of Endotoxin Research , vol.12 , pp. 285-295
    • Nhu, Q.M.1    Cuesta, N.2    Vogel, S.N.3
  • 26
    • 33646427702 scopus 로고    scopus 로고
    • Tlr4-dependent hepcidin expression by myeloid cells in response to bacterial pathogens
    • Peyssonnaux, C., A.S. Zinkernagel, V. Datta, X. Lauth, R.S. Johnson, and V. Nizet. 2006. TLR4-dependent hepcidin expression by myeloid cells in response to bacterial pathogens. Blood 107: 3727-32.
    • (2006) Blood , vol.107 , pp. 3727-32
    • Peyssonnaux, C.1    Zinkernagel, A.S.2    Datta, V.3    Lauth, X.4    Johnson, R.S.5    Nizet, V.6
  • 27
    • 0038662619 scopus 로고    scopus 로고
    • Hepcidin, a putative mediator of anemia of inflammation, is a type ii acute-phase protein
    • Nemeth, E., E.V. Valore, M. Territo, G. Schiller, A. Lichtenstein, and T. Ganz. 2003. Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein. Blood 101: 2461-3.
    • (2003) Blood , vol.101 , pp. 2461-3
    • Nemeth, E.1    Valore, E.V.2    Territo, M.3    Schiller, G.4    Lichtenstein, A.5    Ganz, T.6
  • 28
    • 3042636759 scopus 로고    scopus 로고
    • The il-6-And lipopolysaccharide-induced transcription of hepcidin in hfe-, transferrin receptor 2-, and beta 2-microglobulin-deficient hepatocytes
    • Lee, P., H. Peng, T. Gelbart, and E. Beutler. 2004. The IL-6-And lipopolysaccharide-induced transcription of hepcidin in HFE-, transferrin receptor 2-, and beta 2-microglobulin-deficient hepatocytes. Proc Natl Acad Sci USA 101: 9263-5.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 9263-5
    • Lee, P.1    Peng, H.2    Gelbart, T.3    Beutler, E.4
  • 29
    • 39649097642 scopus 로고    scopus 로고
    • Evidence for differential effects of hepcidin in macrophages and intestinal epithelial cells
    • Chaston, T., B. Chung,M.Mascarenhas, J.Marks, B. Patel, S.K. Srai, and P. Sharp. 2008. Evidence for differential effects of hepcidin in macrophages and intestinal epithelial cells. Gut 57: 374-382.
    • (2008) Gut , vol.57 , pp. 374-382
    • Chaston, T.1    Chung, B.2    Marks, J.3    Patel, B.4    Srai, S.K.5    Sharp, P.6
  • 31
    • 78751528711 scopus 로고    scopus 로고
    • Bacteriostatic activity of the proregion of human hepcidin
    • Barthe, C., A. Hocquellet, and B. Garbay. 2011. Bacteriostatic activity of the proregion of human hepcidin. Protein and Peptide Letters 18: 36-40.
    • (2011) Protein and Peptide Letters , vol.18 , pp. 36-40
    • Barthe, C.1    Hocquellet, A.2    Garbay, B.3
  • 35
    • 53149123286 scopus 로고    scopus 로고
    • Attenuated inflammatory responses in hemochromatosis reveal a role for iron in the regulation of macrophage cytokine translation
    • Wang, L., E.E. Johnson, H.N. Shi, W.A. Walker, M. Wessling-Resnick, and B.J. Cherayil. 2008. Attenuated inflammatory responses in hemochromatosis reveal a role for iron in the regulation of macrophage cytokine translation. Journal of Immunology 181: 2723-2731.
    • (2008) Journal of Immunology , vol.181 , pp. 2723-2731
    • Wang, L.1    Johnson, E.E.2    Shi, H.N.3    Walker, W.A.4    Wessling-Resnick, M.5    Cherayil, B.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.