The IL-6- and lipopolysaccharide-induced transcription of hepcidin in HFE-, transferrin receptor 2-, and β2-microglobulin-deficient hepatocytes

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 25, 2004, Pages 9263-9265

  Lee, Pauline ^a   Peng, Hongfan ^a   Gelbart, Terri ^a   Beutler, Ernest ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; BETA 2 MICROGLOBULIN; CYTOKINE; ENDOTOXIN; HEMOJUVELIN; HEPCIDIN; HFE PROTEIN; INTERLEUKIN 6; IRON; LIPOPOLYSACCHARIDE; PROTEIN; TRANSFERRIN RECEPTOR; TRANSFERRIN RECEPTOR 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; GENE; GENE DISRUPTION; GENE MUTATION; GENETIC TRANSCRIPTION; HAMP GENE; IRON BALANCE; IRON OVERLOAD; LIVER CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; BETA 2-MICROGLOBULIN; CELLS, CULTURED; DNA PRIMERS; HEPATOCYTES; HISTOCOMPATIBILITY ANTIGENS CLASS I; INTERLEUKIN-6; KINETICS; LIPOPOLYSACCHARIDES; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; POLYMERASE CHAIN REACTION; RECEPTORS, TRANSFERRIN; TRANSCRIPTION, GENETIC;

ANIMALIA;

EID: 3042636759     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0403108101     Document Type: Article

References (11)

1. Pigeon, C., Ilyin, G., Courselaud, B., Leroyer, P., Turlin, B., Brissot, P. & Loreal, O. (2001) J. Biol. Chem. 276, 7811-7819.
2. Nemeth, E., Valore, E. V., Territo, M., Schiller, G., Lichtenstein, A. & Ganz, T. (2003) Blood 101, 2461-2463.
3. Gehrke, S. G., Kulaksiz, H., Herrmann, T., Riedel, H. D., Bents, K., Veltkamp, C. & Stremmel, W. (2003) Blood 102, 371-376.
4. Ahmad, K. A., Ahmann, J. R., Migas, M. C., Waheed, A., Britton, R. S., Bacon, B. R., Sly, W. S. & Fleming, R. E. (2002) Blood Cells Mol. Dis. 29, 361-366.
5. Frazer, D. M. & Anderson, G. J. (2003) Blood Cells Mol. Dis. 30, 288-297.
6. Camaschella, C., Roetto, A., Cali, A., De Gobbi, M., Garozzo, G., Carella, M., Majorano, N., Totaro, A. & Gasparini, P. (2000) Nat. Genet. 25, 14-15.
7. Fleming, R. E., Ahmann, J. R., Migas, M. C., Waheed, A., Koeffler, H. P., Kawabata, H., Britton, R. S., Bacon, B. R. & Sly, W. S. (2002) Proc. Natl. Acad. Sci. USA 99, 10653-10658.
8. Ganz, T. (2003) Blood 102, 783-788.
9. Yeh, K. Y., Yeh, M. & Glass, J. (2004) Am. J. Physiol. 286, G385-G394.
10. Papanikolaou, G., Samuels, M. E., Ludwig, E. H., MacDonald, M. L., Franchini, P. L., Dube, M. P., Andres, L., MacFarlane, J., Sakellaropoulos, N., Politou, M., et al. (2004) Nat. Genet. 36, 77-82.
11. Roy, C. N., Custodio, A. O., De Graaf, J., Schneider, S., Akpan, I., Montross, L. K., Sanchez, M., Gaudino, A., Hentze, M. W., Andrews, N. C., et al. (2004) Nat. Genet. 36, 481-485.