메뉴 건너뛰기




Volumn 46, Issue 4, 2012, Pages 481-495

Mammalian telomere biology

Author keywords

ALT; complex shelterin; mammals; mechanisms of telomere maintenance; replicative senescence; telomerase; telomere; telomere replication; TERRA

Indexed keywords

EUKARYOTA; MAMMALIA; SORICIDAE;

EID: 84866440475     PISSN: 00268933     EISSN: 16083245     Source Type: Journal    
DOI: 10.1134/S0026893312040152     Document Type: Review
Times cited : (9)

References (154)
  • 1
    • 0034490072 scopus 로고    scopus 로고
    • The relationship between spontaneous telomere loss and chromosome instability in a human tumor cell line
    • Fouladi B., Sabatier L., Miller D., Pottier G., Murnane J. P. 2000. The relationship between spontaneous telomere loss and chromosome instability in a human tumor cell line. Neoplasia. 2, 540-554.
    • (2000) Neoplasia. , vol.2 , pp. 540-554
    • Fouladi, B.1    Sabatier, L.2    Miller, D.3    Pottier, G.4    Murnane, J.P.5
  • 2
    • 33646831821 scopus 로고    scopus 로고
    • Telomeres, chromosome instability and cancer
    • Bailey S. M., Murnane J. P. 2006. Telomeres, chromosome instability and cancer. Nucleic Acids Res. 34, 2408-2417.
    • (2006) Nucleic Acids Res. , vol.34 , pp. 2408-2417
    • Bailey, S.M.1    Murnane, J.P.2
  • 3
    • 17144410403 scopus 로고    scopus 로고
    • The loss of a single telomere can result in instability of multiple chromosomes in a human tumor cell line
    • Sabatier L., Ricoul M., Pottier G., Murnane J. P. 2005. The loss of a single telomere can result in instability of multiple chromosomes in a human tumor cell line. Mol. Cancer Res. 3, 139-150.
    • (2005) Mol. Cancer Res. , vol.3 , pp. 139-150
    • Sabatier, L.1    Ricoul, M.2    Pottier, G.3    Murnane, J.P.4
  • 4
    • 0015184804 scopus 로고
    • The principle of marginotomy in the template synthesis of polynucleotides
    • Olovnikov A. M. 1971. The principle of marginotomy in the template synthesis of polynucleotides. Dokl. Akad. Nauk SSSR. 201, 1496-1499.
    • (1971) Dokl. Akad. Nauk SSSR. , vol.201 , pp. 1496-1499
    • Olovnikov, A.M.1
  • 5
    • 0015844590 scopus 로고
    • A theory of marginotomy: The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon
    • Olovnikov A. M. 1973. A theory of marginotomy: The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon. J. Theor. Biol. 41, 181-190.
    • (1973) J. Theor. Biol. , vol.41 , pp. 181-190
    • Olovnikov, A.M.1
  • 6
    • 0037716757 scopus 로고    scopus 로고
    • Telomerase and ATM/Tel1p protect telomeres from nonhomologous end joining
    • Chan S. W., Blackburn E. H. 2003. Telomerase and ATM/Tel1p protect telomeres from nonhomologous end joining. Mol. Cell. 11, 1379-1387.
    • (2003) Mol. Cell. , vol.11 , pp. 1379-1387
    • Chan, S.W.1    Blackburn, E.H.2
  • 7
    • 0001294157 scopus 로고
    • The stability of broken ends of chromosomes in Zea mays
    • McClintock B. 1941. The stability of broken ends of chromosomes in Zea mays. Genetics. 26, 234-282.
    • (1941) Genetics. , vol.26 , pp. 234-282
    • McClintock, B.1
  • 8
    • 0012672047 scopus 로고    scopus 로고
    • Telomeres, telomeric DNA, and Chromosomes
    • Egorov E. E. 2001. Telomeres, telomeric DNA, and Chromosomes. Biol. Membr. 18, 249-256.
    • (2001) Biol. Membr. , vol.18 , pp. 249-256
    • Egorov, E.E.1
  • 10
    • 52949098309 scopus 로고    scopus 로고
    • Human telomere structure and biology
    • Riethman H. 2008. Human telomere structure and biology. Annu. Rev. Gen. Hum. Genet. 9, 1-19.
    • (2008) Annu. Rev. Gen. Hum. Genet. , vol.9 , pp. 1-19
    • Riethman, H.1
  • 11
    • 0031000884 scopus 로고    scopus 로고
    • Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening
    • Makarov V. L., Hirose Y., Langmore J. P. 1997. Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening. Cell. 88, 657-666.
    • (1997) Cell. , vol.88 , pp. 657-666
    • Makarov, V.L.1    Hirose, Y.2    Langmore, J.P.3
  • 12
    • 14844351541 scopus 로고    scopus 로고
    • Human telomeres maintain their overhang length at senescence
    • Chai W., Shay J. W., Wright W. E. 2005. Human telomeres maintain their overhang length at senescence. Mol. Cell. Biol. 25, 2158-2168.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 2158-2168
    • Chai, W.1    Shay, J.W.2    Wright, W.E.3
  • 13
    • 33745045163 scopus 로고    scopus 로고
    • Mouse telocentric sequences reveal a high rate of homogenization and possible role in Robertsonian translocation
    • Kalitsis P., Griffiths B., Choo K. H. A. 2006. Mouse telocentric sequences reveal a high rate of homogenization and possible role in Robertsonian translocation. Proc. Natl. Acad. Sci. U. S. A. 103, 8786-8791.
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 8786-8791
    • Kalitsis, P.1    Griffiths, B.2    Choo, K.H.A.3
  • 14
    • 0037148275 scopus 로고    scopus 로고
    • Telomere maintenance without telomerase
    • Lundblad V. 2002. Telomere maintenance without telomerase. Oncogene. 21, 522-531.
    • (2002) Oncogene. , vol.21 , pp. 522-531
    • Lundblad, V.1
  • 15
    • 0032489012 scopus 로고    scopus 로고
    • TRF2 protects human telomeres from end-to-end fusions
    • van Steensel B., Smogorzewska A., de Lange T. 1998. TRF2 protects human telomeres from end-to-end fusions. Cell. 92, 401-413.
    • (1998) Cell. , vol.92 , pp. 401-413
    • van Steensel, B.1    Smogorzewska, A.2    de Lange, T.3
  • 16
    • 0033605145 scopus 로고    scopus 로고
    • p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2
    • Karlseder J., Broccoli D., Dai Y., Hardy S., de Lange T. 1999. p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2. Science. 283, 1321-1325.
    • (1999) Science. , vol.283 , pp. 1321-1325
    • Karlseder, J.1    Broccoli, D.2    Dai, Y.3    Hardy, S.4    de Lange, T.5
  • 18
    • 34547223439 scopus 로고    scopus 로고
    • Terminal regions of mammal chromosomes: Plasticity and role in evolution
    • Zhdanova N. S., Rubtsov N. B., Minina Yu. M. 2007. Terminal regions of mammal chromosomes: Plasticity and role in evolution. Russ. J. Genet. 43, 721-732.
    • (2007) Russ. J. Genet. , vol.43 , pp. 721-732
    • Zhdanova, N.S.1    Rubtsov, N.B.2    Minina, Y.M.3
  • 19
    • 0034994404 scopus 로고    scopus 로고
    • Human intrachromosomal telomeric-like repeats: Sequence organization and mechanisms of origin
    • Azzalin C. M., Nergadze S. G., Giolotto E. 2001. Human intrachromosomal telomeric-like repeats: Sequence organization and mechanisms of origin. Chromosoma. 110, 75-82.
    • (2001) Chromosoma. , vol.110 , pp. 75-82
    • Azzalin, C.M.1    Nergadze, S.G.2    Giolotto, E.3
  • 20
    • 4644329310 scopus 로고    scopus 로고
    • Insertion of telomeric repeats at intrachromosomal sites during primate evolution
    • Nergadze C. G., Rocchi M., Azzalin C. M., Mondello C., Giulotto E. 2004. Insertion of telomeric repeats at intrachromosomal sites during primate evolution. Genome Res. 14, 1704-1710.
    • (2004) Genome Res. , vol.14 , pp. 1704-1710
    • Nergadze, C.G.1    Rocchi, M.2    Azzalin, C.M.3    Mondello, C.4    Giulotto, E.5
  • 21
    • 0027407146 scopus 로고
    • Hot spot of recombination coincides with an interstitial telomeric sequence in the Armenian hamster
    • Ashley T., Ward T. A. 1993. "Hot spot" of recombination coincides with an interstitial telomeric sequence in the Armenian hamster. Cytogenet. Cell Genet. 62, 169-171.
    • (1993) Cytogenet. Cell Genet. , vol.62 , pp. 169-171
    • Ashley, T.1    Ward, T.A.2
  • 22
    • 0033553455 scopus 로고    scopus 로고
    • Telomeres do D-loop-T-loop
    • Greider C. W. 1999. Telomeres do D-loop-T-loop. Cell. 97, 419-422.
    • (1999) Cell. , vol.97 , pp. 419-422
    • Greider, C.W.1
  • 23
    • 0037023763 scopus 로고    scopus 로고
    • p53 binds telomeric single strand overhangs and t-top jnctions in vtro
    • Stansel R. M., Subramanian D. Griffith J. D. 2002. p53 binds telomeric single strand overhangs and t-top jnctions in vtro. J. Biol. Chem. 277, 11625-11628.
    • (2002) J. Biol. Chem. , vol.277 , pp. 11625-11628
    • Stansel, R.M.1    Subramanian, D.2    Griffith, J.D.3
  • 24
    • 0035812845 scopus 로고    scopus 로고
    • The shortest telomere, not average telomere length, is critical for cell viability and chromosome stability
    • Hemann M. T., Strong M. A., Hao L. Y., Greider C. W. 2001. The shortest telomere, not average telomere length, is critical for cell viability and chromosome stability. Cell. 107, 67-77.
    • (2001) Cell. , vol.107 , pp. 67-77
    • Hemann, M.T.1    Strong, M.A.2    Hao, L.Y.3    Greider, C.W.4
  • 25
    • 0034769105 scopus 로고    scopus 로고
    • Restoration of telomerase activity rescues chromosomal instability and premature aging in Terc-/- mice with short telomeres
    • Samper E., Flores J. M., Blasco M. A. 2001. Restoration of telomerase activity rescues chromosomal instability and premature aging in Terc-/- mice with short telomeres. EMBO Rep. 2, 800-807.
    • (2001) EMBO Rep. , vol.2 , pp. 800-807
    • Samper, E.1    Flores, J.M.2    Blasco, M.A.3
  • 26
    • 24944460598 scopus 로고    scopus 로고
    • Shelterin: The protein complex that shapes and safeguards human telomeres
    • de Lange T. 2005. Shelterin: The protein complex that shapes and safeguards human telomeres. Genes Dev. 19, 2100-2110.
    • (2005) Genes Dev. , vol.19 , pp. 2100-2110
    • de Lange, T.1
  • 27
    • 33745685066 scopus 로고    scopus 로고
    • Recent expansion of the telomeric complex in rodents: Two distinct POT1 proteins protect mouse telomeres
    • Hockemeyer D., Daniels J.-P., Takai H., de Lange T. 2006. Recent expansion of the telomeric complex in rodents: Two distinct POT1 proteins protect mouse telomeres. Cell. 126, 63-77.
    • (2006) Cell. , vol.126 , pp. 63-77
    • Hockemeyer, D.1    Daniels, J.-P.2    Takai, H.3    de Lange, T.4
  • 28
    • 34548492016 scopus 로고    scopus 로고
    • MRE11-RAD50-NBS1 and ATM function as co-mediators of TRF1 in telomere length control
    • Wu Y., Xiao Sh., Zhu X-D. 2007. MRE11-RAD50-NBS1 and ATM function as co-mediators of TRF1 in telomere length control. Nature Struct. Mol. Biol. 14, 832-840.
    • (2007) Nature Struct. Mol. Biol. , vol.14 , pp. 832-840
    • Wu, Y.1    Xiao, S.2    Zhu, X.-D.3
  • 29
    • 70350786918 scopus 로고    scopus 로고
    • Human RAP1 inhibits non-692 homologous end joining at telomeres
    • Sarthy J., Bae N. S., Scrafford J., Baumann P. 2009. Human RAP1 inhibits non-692 homologous end joining at telomeres. EMBO J. 28, 3390-3399.
    • (2009) EMBO J. , vol.28 , pp. 3390-3399
    • Sarthy, J.1    Bae, N.S.2    Scrafford, J.3    Baumann, P.4
  • 31
    • 3543056880 scopus 로고    scopus 로고
    • Functional links between telomeres and proteins of the DNA-damage response
    • d'Adda di Fagagna F., Teo S. H., Jackson S. P. 2004. Functional links between telomeres and proteins of the DNA-damage response. Genes Dev. 18, 1781-1799.
    • (2004) Genes Dev. , vol.18 , pp. 1781-1799
    • d'Adda di Fagagna, F.1    Teo, S.H.2    Jackson, S.P.3
  • 32
    • 0032536861 scopus 로고    scopus 로고
    • Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing
    • Boulton S. J., Jackson S. P. 1998. Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing. EMBO J. 17, 1819-1828.
    • (1998) EMBO J. , vol.17 , pp. 1819-1828
    • Boulton, S.J.1    Jackson, S.P.2
  • 33
    • 0037033062 scopus 로고    scopus 로고
    • Human Ku70/80 associates physically with telomerase through interaction with hTERT
    • Chai W., Ford L. P., Lenertz L., Wright W. E., Shay J. W. 2002. Human Ku70/80 associates physically with telomerase through interaction with hTERT. J. Biol. Chem. 277, 7242-47247.
    • (2002) J. Biol. Chem. , vol.277 , pp. 7242-47247
    • Chai, W.1    Ford, L.P.2    Lenertz, L.3    Wright, W.E.4    Shay, J.W.5
  • 34
    • 0037292398 scopus 로고    scopus 로고
    • The telomere protein Taz1 is required to prevent and repair genomic DNA breaks
    • Miller K. M., Cooper J. P. 2003. The telomere protein Taz1 is required to prevent and repair genomic DNA breaks. Mol. Cell. 11, 303-313.
    • (2003) Mol. Cell. , vol.11 , pp. 303-313
    • Miller, K.M.1    Cooper, J.P.2
  • 35
    • 13944263628 scopus 로고    scopus 로고
    • Human telomeric protein TRF2 associates with genomic double-strand breaks as an early response to DNA damage
    • Bradshaw P. S., Stavropoulos D. J., Meyn M. S. 2005. Human telomeric protein TRF2 associates with genomic double-strand breaks as an early response to DNA damage. Nature Genet. 37, 193-197.
    • (2005) Nature Genet. , vol.37 , pp. 193-197
    • Bradshaw, P.S.1    Stavropoulos, D.J.2    Meyn, M.S.3
  • 37
    • 37349043972 scopus 로고    scopus 로고
    • Telomeric repeat-containing RNA and RNA surveillance factors at mammalian chromosome ends
    • Azzalin C. M., Reichenbach P., Khoriauli L., Giulotto E., and Lingner J. 2007. Telomeric repeat-containing RNA and RNA surveillance factors at mammalian chromosome ends. Science. 318, 798-801.
    • (2007) Science. , vol.318 , pp. 798-801
    • Azzalin, C.M.1    Reichenbach, P.2    Khoriauli, L.3    Giulotto, E.4    Lingner, J.5
  • 38
    • 0035670851 scopus 로고    scopus 로고
    • The snoRNA domain of vertebrate telomerase RNA functions to localize the RNA within the nucleus
    • Lukowiak A. A., Narayanan A., Li Z.-H., Terns R. M., Terns M. P. 2001. The snoRNA domain of vertebrate telomerase RNA functions to localize the RNA within the nucleus. RNA. 7, 1833-1844.
    • (2001) RNA. , vol.7 , pp. 1833-1844
    • Lukowiak, A.A.1    Narayanan, A.2    Li, Z.-H.3    Terns, R.M.4    Terns, M.P.5
  • 39
    • 68949198783 scopus 로고    scopus 로고
    • TERRA RNA binding to TRF2 facilitates heterochromatin formation and ORC recruitment at telomeres
    • Deng Zh., Norseen J., Wiedmer A., Riethman H., Lieberman P. M. 2009. TERRA RNA binding to TRF2 facilitates heterochromatin formation and ORC recruitment at telomeres. Mol. Cell. 35, 403-413.
    • (2009) Mol. Cell. , vol.35 , pp. 403-413
    • Deng, Z.1    Norseen, J.2    Wiedmer, A.3    Riethman, H.4    Lieberman, P.M.5
  • 40
    • 77957243987 scopus 로고    scopus 로고
    • The noncoding RNA TERRA is a natural ligand and direct inhibitor of human telomerase
    • Redon S., Reichenbach P., Lingner J. 2010. The noncoding RNA TERRA is a natural ligand and direct inhibitor of human telomerase. Nucleic Acids Res. 38, 5797-5806.
    • (2010) Nucleic Acids Res. , vol.38 , pp. 5797-5806
    • Redon, S.1    Reichenbach, P.2    Lingner, J.3
  • 41
    • 69849104275 scopus 로고    scopus 로고
    • TERRA: Telomeric repeatcontaining RNA
    • Luke B., Lingner J. 2009. TERRA: Telomeric repeatcontaining RNA. EMBO J. 28, 2503-2510.
    • (2009) EMBO J. , vol.28 , pp. 2503-2510
    • Luke, B.1    Lingner, J.2
  • 42
  • 44
    • 0034597794 scopus 로고    scopus 로고
    • Telomere states and cell fates
    • Blackburn E. H. 2000. Telomere states and cell fates. Nature. 408, 53-56.
    • (2000) Nature. , vol.408 , pp. 53-56
    • Blackburn, E.H.1
  • 45
    • 2042429168 scopus 로고    scopus 로고
    • Regulation of telomerase by telomeric proteins
    • Smogorzewska A., de Lange T. 2004. Regulation of telomerase by telomeric proteins. Annu. Rev. Biochem. 73, 177-208.
    • (2004) Annu. Rev. Biochem. , vol.73 , pp. 177-208
    • Smogorzewska, A.1    de Lange, T.2
  • 49
    • 0024978857 scopus 로고
    • A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis
    • Greider C. W., Blackburn E. H. 1989. A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis. Nature. 337, 331-337.
    • (1989) Nature. , vol.337 , pp. 331-337
    • Greider, C.W.1    Blackburn, E.H.2
  • 51
  • 52
    • 34147095342 scopus 로고    scopus 로고
    • Protein composition of catalytically active human telomerase from immortal cells
    • Cohen S. B., Graham M. E., Lovrecz G. O., Bache N., Robinson P. J., Reddel R. R. 2007. Protein composition of catalytically active human telomerase from immortal cells. Science. 315, 1850-1853.
    • (2007) Science. , vol.315 , pp. 1850-1853
    • Cohen, S.B.1    Graham, M.E.2    Lovrecz, G.O.3    Bache, N.4    Robinson, P.J.5    Reddel, R.R.6
  • 60
    • 68049088928 scopus 로고    scopus 로고
    • Telomere extension occurs at most chromosome ends and is uncoupled from fill-in in human cancer cells
    • Zhao Y., Sfeir A. J., Zou Y., Buseman C. M., Chow T. T., Shay J. M., Wright W. E. 2009. Telomere extension occurs at most chromosome ends and is uncoupled from fill-in in human cancer cells. Cell. 138, 463-475.
    • (2009) Cell. , vol.138 , pp. 463-475
    • Zhao, Y.1    Sfeir, A.J.2    Zou, Y.3    Buseman, C.M.4    Chow, T.T.5    Shay, J.M.6    Wright, W.E.7
  • 61
    • 77955402694 scopus 로고    scopus 로고
    • Telomerase in the ovary
    • Liu J.-P., Li H. 2010. Telomerase in the ovary. Reproduction. 140, 215-222.
    • (2010) Reproduction. , vol.140 , pp. 215-222
    • Liu, J.-P.1    Li, H.2
  • 63
    • 0025279931 scopus 로고
    • Telomeres shorten during ageing of human fibroblasts
    • Harley C. B., Futcher A. B., Greider C. W. 1990. Telomeres shorten during ageing of human fibroblasts. Nature. 345, 458-460.
    • (1990) Nature. , vol.345 , pp. 458-460
    • Harley, C.B.1    Futcher, A.B.2    Greider, C.W.3
  • 64
    • 0030006735 scopus 로고    scopus 로고
    • In situ analysis of change in telomere size during replicative aging and cell transformation
    • Henderson S., Allsopp R., Spector D., Wang S. S., Harley C. 1996. In situ analysis of change in telomere size during replicative aging and cell transformation. J. Cell Biol. 134, 1-12.
    • (1996) J. Cell Biol. , vol.134 , pp. 1-12
    • Henderson, S.1    Allsopp, R.2    Spector, D.3    Wang, S.S.4    Harley, C.5
  • 67
    • 0029872174 scopus 로고
    • Telomerase activity in human germline and embryonic tissues and cells
    • Wright W. E., Piatyszek M. A., Rainey W. E., Byrd W., Shay J. W. 1995. Telomerase activity in human germline and embryonic tissues and cells. Dev. Genet. 18, 173-179.
    • (1995) Dev. Genet. , vol.18 , pp. 173-179
    • Wright, W.E.1    Piatyszek, M.A.2    Rainey, W.E.3    Byrd, W.4    Shay, J.W.5
  • 68
    • 0035929353 scopus 로고    scopus 로고
    • Switching and signaling at the telomere
    • Blackburn E. H. 2001. Switching and signaling at the telomere. Cell. 106, 661-673.
    • (2001) Cell. , vol.106 , pp. 661-673
    • Blackburn, E.H.1
  • 69
    • 22944488871 scopus 로고    scopus 로고
    • Telomeres and human disease: Aging, cancer and beyond
    • Blasco M. A. 2005. Telomeres and human disease: Aging, cancer and beyond. Nature Rev. Genet. 6, 611-622.
    • (2005) Nature Rev. Genet. , vol.6 , pp. 611-622
    • Blasco, M.A.1
  • 73
    • 78651228154 scopus 로고    scopus 로고
    • Reprogramming of telomeric regions during the generation of human induced pluripotent stem cells and subsequent differentiation into fibro-blast-like derivatives
    • Yehezkel S., Rebibo-Sabbah A., Segev Y., Tzukerman M., Shaked R., Huber I., Gepstein L., Skorecki K., Selig S. 2011. Reprogramming of telomeric regions during the generation of human induced pluripotent stem cells and subsequent differentiation into fibro-blast-like derivatives. Epigenetics. 6, 63-75.
    • (2011) Epigenetics. , vol.6 , pp. 63-75
    • Yehezkel, S.1    Rebibo-Sabbah, A.2    Segev, Y.3    Tzukerman, M.4    Shaked, R.5    Huber, I.6    Gepstein, L.7    Skorecki, K.8    Selig, S.9
  • 76
    • 80053082069 scopus 로고    scopus 로고
    • Different telomere-length dynamics at the inner cell mass versus established embryonic stem (ES) cells
    • Varela E., Schneider R. P., Ortega S., Blasco M. A. 2011. Different telomere-length dynamics at the inner cell mass versus established embryonic stem (ES) cells. Proc. Natl. Acad. Sci. U. S. A. 108, 15207-15212.
    • (2011) Proc. Natl. Acad. Sci. U. S. A. , vol.108 , pp. 15207-15212
    • Varela, E.1    Schneider, R.P.2    Ortega, S.3    Blasco, M.A.4
  • 77
    • 0037192462 scopus 로고    scopus 로고
    • Senescence induced by altered telomere state, not telomere loss
    • Karlseder J., Smogorzewska A., de Lange T. 2002. Senescence induced by altered telomere state, not telomere loss. Science. 295, 2446-2449.
    • (2002) Science. , vol.295 , pp. 2446-2449
    • Karlseder, J.1    Smogorzewska, A.2    de Lange, T.3
  • 79
    • 0025029030 scopus 로고
    • Hypervariable ultra-long telomeres in mice
    • Kipling D., Cooke H. J. 1990. Hypervariable ultra-long telomeres in mice. Nature. 347, 400-402.
    • (1990) Nature. , vol.347 , pp. 400-402
    • Kipling, D.1    Cooke, H.J.2
  • 81
    • 19844382620 scopus 로고    scopus 로고
    • Senescence and immortalization: Role of telomeres and telomerase
    • Shay J. W., Wright W. E. 2005. Senescence and immortalization: Role of telomeres and telomerase. Carcinogenesis. 26, 867-874.
    • (2005) Carcinogenesis. , vol.26 , pp. 867-874
    • Shay, J.W.1    Wright, W.E.2
  • 82
    • 0344622606 scopus 로고
    • The serial cultivation of human diploid cell strains
    • Hayflick L., Moorhead P. S. 1961. The serial cultivation of human diploid cell strains. Exp. Cell Res. 25, 595-621.
    • (1961) Exp. Cell Res. , vol.25 , pp. 595-621
    • Hayflick, L.1    Moorhead, P.S.2
  • 84
    • 0036782884 scopus 로고    scopus 로고
    • Telomerase: A target for cancer therapeutics
    • Shay J. W., Wright W. E. 2002. Telomerase: A target for cancer therapeutics. Cancer Cell. 2, 257-265.
    • (2002) Cancer Cell. , vol.2 , pp. 257-265
    • Shay, J.W.1    Wright, W.E.2
  • 85
    • 77955845914 scopus 로고    scopus 로고
    • Telomeres and telomerase in normal and cancer stem cells
    • Shay J. W., Wright W. E. 2010. Telomeres and telomerase in normal and cancer stem cells. FEBS Lett. 584, 3819-3825.
    • (2010) FEBS Lett. , vol.584 , pp. 3819-3825
    • Shay, J.W.1    Wright, W.E.2
  • 86
    • 34548667973 scopus 로고    scopus 로고
    • Telomere length, stem cells and aging
    • Blasco M. A. 2007. Telomere length, stem cells and aging. Nature Chem. Biol. 3, 640-649.
    • (2007) Nature Chem. Biol. , vol.3 , pp. 640-649
    • Blasco, M.A.1
  • 88
    • 0038451396 scopus 로고    scopus 로고
    • POT1 as a terminal transducer of TRF1 telomere length control
    • Loayza D., De Lange T. 2003. POT1 as a terminal transducer of TRF1 telomere length control. Nature. 423, 1013-1018.
    • (2003) Nature. , vol.423 , pp. 1013-1018
    • Loayza, D.1    de Lange, T.2
  • 89
    • 4544258775 scopus 로고    scopus 로고
    • Dynamic molecular link between the telomere length regulator TRF1 and the chromosome end protector TRF2
    • Houghtaling B. R., Cuttonaro L., Chang W., Smith S. A. 2004. Dynamic molecular link between the telomere length regulator TRF1 and the chromosome end protector TRF2. Curr. Biol. 14, 1621-1631.
    • (2004) Curr. Biol. , vol.14 , pp. 1621-1631
    • Houghtaling, B.R.1    Cuttonaro, L.2    Chang, W.3    Smith, S.A.4
  • 90
    • 65449187067 scopus 로고    scopus 로고
    • Control of telomere length by a trimming mechanism that involves generation of t-circles
    • Pickett H. A., Cesare A. J., Johnstone R. L., Neumann A. A., Reddel R. R. 2009. Control of telomere length by a trimming mechanism that involves generation of t-circles. EMBO J. 28, 799-809.
    • (2009) EMBO J. , vol.28 , pp. 799-809
    • Pickett, H.A.1    Cesare, A.J.2    Johnstone, R.L.3    Neumann, A.A.4    Reddel, R.R.5
  • 91
    • 0242354121 scopus 로고    scopus 로고
    • Clues to catastrophic telomere loss in mammals from yeast telomere rapid deletion
    • Lustig A. J. 2003. Clues to catastrophic telomere loss in mammals from yeast telomere rapid deletion. Nature Rev. Genet. 4, 916-923.
    • (2003) Nature Rev. Genet. , vol.4 , pp. 916-923
    • Lustig, A.J.1
  • 92
    • 33847187005 scopus 로고    scopus 로고
    • Telomere rapid deletion regulates telomere length in Arabidopsis thaliana
    • Watson J. M., Shippen D. E. 2007. Telomere rapid deletion regulates telomere length in Arabidopsis thaliana. Mol. Cell. Biol. 27, 1706-1715.
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 1706-1715
    • Watson, J.M.1    Shippen, D.E.2
  • 93
    • 81255209208 scopus 로고    scopus 로고
    • Normal mammalian cells negatively regulate telomere length by telomere trimming
    • Pickett H. A., Henson J. D., Au A. Y., Neumann A. A., Reddel R. R. 2011. Normal mammalian cells negatively regulate telomere length by telomere trimming. Hum. Mol. Genet. 20, 4684-4892.
    • (2011) Hum. Mol. Genet. , vol.20 , pp. 4684-4892
    • Pickett, H.A.1    Henson, J.D.2    Au, A.Y.3    Neumann, A.A.4    Reddel, R.R.5
  • 94
    • 36749019586 scopus 로고    scopus 로고
    • Telomere dynamics in human cells
    • Baird D. M. 2008. Telomere dynamics in human cells. Biochimie. 90, 116-121.
    • (2008) Biochimie. , vol.90 , pp. 116-121
    • Baird, D.M.1
  • 95
    • 0037687623 scopus 로고    scopus 로고
    • Alternative lengthening of telomeres, telomerase, and cancer
    • Reddel R. R. 2003. Alternative lengthening of telomeres, telomerase, and cancer. Cancer Lett. 194, 155-162.
    • (2003) Cancer Lett. , vol.194 , pp. 155-162
    • Reddel, R.R.1
  • 96
    • 77953699259 scopus 로고    scopus 로고
    • The effects of telomerase inhibition on prostate tumor-initiating cells
    • Marian C. O., Wright W. E., Shay J. W. 2010. The effects of telomerase inhibition on prostate tumor-initiating cells. Int. J. Cancer. 127, 321-331.
    • (2010) Int. J. Cancer. , vol.127 , pp. 321-331
    • Marian, C.O.1    Wright, W.E.2    Shay, J.W.3
  • 97
    • 0029162563 scopus 로고
    • Telomere elongation in immortal human cells without detectable telomerase activity
    • Bryan T. M., Englezou A., Gupta J., Bacchetti S., Reddel R. R. 1995. Telomere elongation in immortal human cells without detectable telomerase activity. EMBO J. 14, 4240-4248.
    • (1995) EMBO J. , vol.14 , pp. 4240-4248
    • Bryan, T.M.1    Englezou, A.2    Gupta, J.3    Bacchetti, S.4    Reddel, R.R.5
  • 98
    • 77955846020 scopus 로고    scopus 로고
    • Assaying and investigating alternative lengthening of telomeres
    • Henson J. D., Reddel. R. R. 2010. Assaying and investigating alternative lengthening of telomeres. FEBS Lett. 584, 3800-3811.
    • (2010) FEBS Lett. , vol.584 , pp. 3800-3811
    • Henson, J.D.1    Reddel, R.R.2
  • 101
    • 0036510162 scopus 로고    scopus 로고
    • Molecular characterization of inter-telomere and intra-telomere mutations in human ALT cells
    • Varley H., Pickett H. A., Foxon J. L., Reddel R. R., Royle N. J. 2002. Molecular characterization of inter-telomere and intra-telomere mutations in human ALT cells. Nature Genet. 30, 301-305.
    • (2002) Nature Genet. , vol.30 , pp. 301-305
    • Varley, H.1    Pickett, H.A.2    Foxon, J.L.3    Reddel, R.R.4    Royle, N.J.5
  • 103
    • 0347093485 scopus 로고    scopus 로고
    • Homologous recombination in human telomerasepositive and ALT cells occurs with the same frequency
    • Bechter O. E., Zou Y., Shay J. W., Wright W. E. 2003. Homologous recombination in human telomerasepositive and ALT cells occurs with the same frequency. EMBO Rep. 4, 1138-1143.
    • (2003) EMBO Rep. , vol.4 , pp. 1138-1143
    • Bechter, O.E.1    Zou, Y.2    Shay, J.W.3    Wright, W.E.4
  • 104
    • 1942538563 scopus 로고    scopus 로고
    • Alternative lengthening of telomeres is characterized by high rates of telomeric exchange
    • Londono-Vallejo J. A., Der-Sarkissian H., Cazes L., et al. 2004. Alternative lengthening of telomeres is characterized by high rates of telomeric exchange. Cancer Res. 64, 2324-2327.
    • (2004) Cancer Res. , vol.64 , pp. 2324-2327
    • Londono-Vallejo, J.A.1    Der-Sarkissian, H.2    Cazes, L.3
  • 105
    • 3142699748 scopus 로고    scopus 로고
    • Frequent recombination in telomeric DNA may extend the proliferative life of telomerase-negative cells
    • Bailey S. M., Brenneman M. A., Goodwin E. H. 2004. Frequent recombination in telomeric DNA may extend the proliferative life of telomerase-negative cells. Nucleic Acids Res. 32, 3743-3751.
    • (2004) Nucleic Acids Res. , vol.32 , pp. 3743-3751
    • Bailey, S.M.1    Brenneman, M.A.2    Goodwin, E.H.3
  • 109
    • 59249090880 scopus 로고    scopus 로고
    • Unusual telomeric DNAs in human telomerase-negative immortalized cells
    • Nabetani A., Ishikawa F. 2009. Unusual telomeric DNAs in human telomerase-negative immortalized cells. Mol. Cell. Biol. 29, 703-713.
    • (2009) Mol. Cell. Biol. , vol.29 , pp. 703-713
    • Nabetani, A.1    Ishikawa, F.2
  • 110
    • 77951133257 scopus 로고    scopus 로고
    • Alternative lengthening of telomeres: Models, mechanisms and implications
    • Cesare A. J., Reddel R. R. 2010. Alternative lengthening of telomeres: Models, mechanisms and implications. Nature Rev. Genet. 11, 319-330.
    • (2010) Nature Rev. Genet. , vol.11 , pp. 319-330
    • Cesare, A.J.1    Reddel, R.R.2
  • 111
    • 78650662899 scopus 로고    scopus 로고
    • Alternative lengthening of telomeres pathway: Recombination-mediated telomere maintenance mechanism in human cells
    • Nabetani A., Ishikawa F. 2011. Alternative lengthening of telomeres pathway: Recombination-mediated telomere maintenance mechanism in human cells. J. Biochem. 149, 5-14.
    • (2011) J. Biochem. , vol.149 , pp. 5-14
    • Nabetani, A.1    Ishikawa, F.2
  • 112
    • 0033513079 scopus 로고    scopus 로고
    • Telomere-telomere recombination is an efficient bypass pathway for telomere maintenance in Saccharomyces cerevisiae
    • Teng S. C. Zakian V. A. 1999. Telomere-telomere recombination is an efficient bypass pathway for telomere maintenance in Saccharomyces cerevisiae. Mol. Cell. Biol. 19, 8083-8093.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 8083-8093
    • Teng, S.C.1    Zakian, V.A.2
  • 113
    • 0032959506 scopus 로고    scopus 로고
    • RAD51 and RAD50 define two pathways that collaborate to maintain telomeres in the absence of telomerase
    • Le S., Moore J. K., Haber J. E., Greider C. W. 1999. RAD51 and RAD50 define two pathways that collaborate to maintain telomeres in the absence of telomerase. Genetics. 152, 143-152.
    • (1999) Genetics. , vol.152 , pp. 143-152
    • Le, S.1    Moore, J.K.2    Haber, J.E.3    Greider, C.W.4
  • 114
    • 13944265075 scopus 로고    scopus 로고
    • Late S phasespecific recruitment of Mre11 complex triggers hierarchical assembly of telomere replication proteins in Saccharomyces cerevisiae
    • Takata H., Tanaka Y., Matsuura A. 2005. Late S phasespecific recruitment of Mre11 complex triggers hierarchical assembly of telomere replication proteins in Saccharomyces cerevisiae. Mol. Cell. 18, 573-583.
    • (2005) Mol. Cell. , vol.18 , pp. 573-583
    • Takata, H.1    Tanaka, Y.2    Matsuura, A.3
  • 115
    • 33745474120 scopus 로고    scopus 로고
    • Break-induced replication and recombinational telomere elongation in yeast
    • McEachern M. J., Haber J. E. 2006. Break-induced replication and recombinational telomere elongation in yeast. Annu. Rev. Biochem. 75, 111-135.
    • (2006) Annu. Rev. Biochem. , vol.75 , pp. 111-135
    • McEachern, M.J.1    Haber, J.E.2
  • 116
    • 15044357804 scopus 로고    scopus 로고
    • Suppression of alternative lengthening of telomeres by Sp100-mediated sequestration of the MRE11/RAD50/NBS1 complex
    • Jiang W. Q., Zhong Z. H., Henson J. D. Neumann A. A., Chang A. C.-M., Reddel R. R. 2005. Suppression of alternative lengthening of telomeres by Sp100-mediated sequestration of the MRE11/RAD50/NBS1 complex. Mol. Cell. Biol. 25, 2708-2721.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 2708-2721
    • Jiang, W.Q.1    Zhong, Z.H.2    Henson, J.D.3    Neumann, A.A.4    Chang, A.C.-M.5    Reddel, R.R.6
  • 117
    • 0036311563 scopus 로고    scopus 로고
    • Involvement of replicative polymerases, Tel1p, Mec1p, Cdc13p, and the Ku complex in telomeretelomere recombination
    • Tsai Y. L., Tseng S. F., Chang S. H., Lin C.-C., Teng S.-C. 2002. Involvement of replicative polymerases, Tel1p, Mec1p, Cdc13p, and the Ku complex in telomeretelomere recombination. Mol. Cell. Biol. 22, 5679-5687.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 5679-5687
    • Tsai, Y.L.1    Tseng, S.F.2    Chang, S.H.3    Lin, C.-C.4    Teng, S.-C.5
  • 118
    • 34447129654 scopus 로고    scopus 로고
    • The SMC5/6 complex maintains telomere length in ALT cancer cells through SUMOylation of telomere-binding proteins
    • Potts P. R., Yu H. 2007. The SMC5/6 complex maintains telomere length in ALT cancer cells through SUMOylation of telomere-binding proteins. Nature Struct. Mol. Biol. 14, 581-590.
    • (2007) Nature Struct. Mol. Biol. , vol.14 , pp. 581-590
    • Potts, P.R.1    Yu, H.2
  • 119
    • 2942623564 scopus 로고    scopus 로고
    • Localization of hRad9, hHus1, hRad1, and hRad17 and caffeine-sensitive DNA replication at the alternative lengthening of telomeres-associated promyelocytic leukemia body
    • Nabetani A., Yokoyama O., Ishikawa F. 2004. Localization of hRad9, hHus1, hRad1, and hRad17 and caffeine-sensitive DNA replication at the alternative lengthening of telomeres-associated promyelocytic leukemia body. J. Biol. Chem. 279, 25849-25857.
    • (2004) J. Biol. Chem. , vol.279 , pp. 25849-25857
    • Nabetani, A.1    Yokoyama, O.2    Ishikawa, F.3
  • 121
    • 59249101446 scopus 로고    scopus 로고
    • Short telomeres initiate telomere recombination in primary and tumor cells
    • Morrish T. A., Greider C. W. 2009. Short telomeres initiate telomere recombination in primary and tumor cells. PLoS Genet. 5, e1000357.
    • (2009) PLoS Genet. , vol.5
    • Morrish, T.A.1    Greider, C.W.2
  • 122
    • 0033519630 scopus 로고    scopus 로고
    • Repression of an alternative mechanism for lengthening of telomeres in somatic cell hybrids
    • Perrem K., Bryan T. M., Englezou A., Hackl T., Moy E. L., Reddel R. R. 1999. Repression of an alternative mechanism for lengthening of telomeres in somatic cell hybrids. Oncogene. 18, 3383-3390.
    • (1999) Oncogene. , vol.18 , pp. 3383-3390
    • Perrem, K.1    Bryan, T.M.2    Englezou, A.3    Hackl, T.4    Moy, E.L.5    Reddel, R.R.6
  • 123
    • 0034998040 scopus 로고    scopus 로고
    • Coexistence of alternative lengthening of telomeres and telomerase in hTERT-transfected GM847 cells
    • Perrem K., Colgin L. M., Neumann A. A., Yeager T. R., Reddel R. R. 2001. Coexistence of alternative lengthening of telomeres and telomerase in hTERT-transfected GM847 cells. Mol. Cell. Biol. 21, 3862-3875.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 3862-3875
    • Perrem, K.1    Colgin, L.M.2    Neumann, A.A.3    Yeager, T.R.4    Reddel, R.R.5
  • 124
    • 0035943603 scopus 로고    scopus 로고
    • Telomerase can inhibit the recombination-based pathway of telomere maintenance in human cells
    • Ford L. P., Zou Y., Pongracz K., Gryaznov S. M., Shay J. W., Wright W. E. 2001. Telomerase can inhibit the recombination-based pathway of telomere maintenance in human cells. J. Biol. Chem. 276, 32198-32203.
    • (2001) J. Biol. Chem. , vol.276 , pp. 32198-32203
    • Ford, L.P.1    Zou, Y.2    Pongracz, K.3    Gryaznov, S.M.4    Shay, J.W.5    Wright, W.E.6
  • 125
    • 0035445809 scopus 로고    scopus 로고
    • Effects of reconstitution of telomerase activity on telomere maintenance by the alternative lengthening of telomeres (ALT) pathway
    • Grobelny J. V., Kulp-McEliece M., Broccoli D. 2001. Effects of reconstitution of telomerase activity on telomere maintenance by the alternative lengthening of telomeres (ALT) pathway. Hum. Mol. Genet. 10, 1953-1961.
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 1953-1961
    • Grobelny, J.V.1    Kulp-McEliece, M.2    Broccoli, D.3
  • 127
    • 0041661943 scopus 로고    scopus 로고
    • Nuclear and territorial topography of chromosome telomeres in human lymphocytes
    • Amrichova J., Lukasova E., Kozubek S., Kozubek M. 2003. Nuclear and territorial topography of chromosome telomeres in human lymphocytes. Exp. Cell Res. 289, 11-26.
    • (2003) Exp. Cell Res. , vol.289 , pp. 11-26
    • Amrichova, J.1    Lukasova, E.2    Kozubek, S.3    Kozubek, M.4
  • 128
    • 0043180471 scopus 로고    scopus 로고
    • Three-dimensional arrangements of centromeres and telomeres in nuclei of human and murine lymphocytes
    • Weierich C., Brero A., Stein S., von Hase J., Cremer C., Cremer T., Solovei I. 2003. Three-dimensional arrangements of centromeres and telomeres in nuclei of human and murine lymphocytes. Chromosome Res. 11, 485-502.
    • (2003) Chromosome Res. , vol.11 , pp. 485-502
    • Weierich, C.1    Brero, A.2    Stein, S.3    von Hase, J.4    Cremer, C.5    Cremer, T.6    Solovei, I.7
  • 129
    • 0029827128 scopus 로고    scopus 로고
    • Structure, subnuclear distribution, and nuclear matrix association of the mammalian telomeric complex
    • Luderus M. E., van Steensel B., Chong L., Sibon O. C., Cremers F. F., de Lange T. 1996. Structure, subnuclear distribution, and nuclear matrix association of the mammalian telomeric complex. J. Cell Biol. 135, 867-881.
    • (1996) J. Cell Biol. , vol.135 , pp. 867-881
    • Luderus, M.E.1    van Steensel, B.2    Chong, L.3    Sibon, O.C.4    Cremers, F.F.5    de Lange, T.6
  • 131
    • 59349105194 scopus 로고    scopus 로고
    • The nuclear lamina promotes telomere aggregation and centromere peripheral localization during senescence of human mesenchymal stem cells
    • Raz V., Vermolen B. J., Garini Y., Onderwater J. J., Mommaas-Kienhuis M. A., Koster A. J., Young I. T., Tanke H., Dirks R. W. 2008. The nuclear lamina promotes telomere aggregation and centromere peripheral localization during senescence of human mesenchymal stem cells. J. Cell Sci. 121(24), 4018-4028.
    • (2008) J. Cell Sci. , vol.121 , Issue.24 , pp. 4018-4028
    • Raz, V.1    Vermolen, B.J.2    Garini, Y.3    Onderwater, J.J.4    Mommaas-Kienhuis, M.A.5    Koster, A.J.6    Young, I.T.7    Tanke, H.8    Dirks, R.W.9
  • 132
    • 57749122172 scopus 로고    scopus 로고
    • Release of yeast telomeres from the nuclear periphery is triggered by replication and maintained by suppression of Kumediated anchoring
    • Ebrahimi H., Donaldson A. D. 2008. Release of yeast telomeres from the nuclear periphery is triggered by replication and maintained by suppression of Kumediated anchoring. Genes Dev. 22, 3363-3374.
    • (2008) Genes Dev. , vol.22 , pp. 3363-3374
    • Ebrahimi, H.1    Donaldson, A.D.2
  • 133
    • 46349091454 scopus 로고    scopus 로고
    • Three-dimensional organization of interphase fibroblast nuclei in two closely related shrew species (Sorex granarius and Sorex araneus) differing in the structures of their chromosome termini
    • Rubtsov N. B., Karamysheva T. V., Minina Yu. M., Zhdanova N. S. 2008. Three-dimensional organization of interphase fibroblast nuclei in two closely related shrew species (Sorex granarius and Sorex araneus) differing in the structures of their chromosome termini. Cell Tiss. Biol. 2, 222-231.
    • (2008) Cell Tiss. Biol. , vol.2 , pp. 222-231
    • Rubtsov, N.B.1    Karamysheva, T.V.2    Minina, Y.M.3    Zhdanova, N.S.4
  • 134
    • 79955524480 scopus 로고    scopus 로고
    • Rap1-independent telomere attachment and bouquet formation in mammalian meiosis
    • Scherthan H., Sfeir A., de Lange T. 2011. Rap1-independent telomere attachment and bouquet formation in mammalian meiosis. Chromosoma. 120, 151-157.
    • (2011) Chromosoma. , vol.120 , pp. 151-157
    • Scherthan, H.1    Sfeir, A.2    de Lange, T.3
  • 136
    • 0034669532 scopus 로고    scopus 로고
    • Wild-derived inbred mouse strains have short telomeres
    • Hemann M. T., Greider C. W. 2000. Wild-derived inbred mouse strains have short telomeres. Nucleic Acids Res. 28, 4474-4478.
    • (2000) Nucleic Acids Res. , vol.28 , pp. 4474-4478
    • Hemann, M.T.1    Greider, C.W.2
  • 139
    • 70349095903 scopus 로고    scopus 로고
    • Telomeric DNA allocation in chromosomes of common shrew (Sorex araneus, Eulipotyphla)
    • Zhdanova N. S., Rogozina Yu. I., Minina Yu. M., Borodin P. M., Rubtsov N. B. 2009. Telomeric DNA allocation in chromosomes of common shrew (Sorex araneus, Eulipotyphla). Cell Tiss. Biol. 3, 323-329.
    • (2009) Cell Tiss. Biol. , vol.3 , pp. 323-329
    • Zhdanova, N.S.1    Rogozina, Y.I.2    Minina, Y.M.3    Borodin, P.M.4    Rubtsov, N.B.5
  • 140
    • 0036242246 scopus 로고    scopus 로고
    • Influence of inbreeding and genetics on telomere length in mice
    • Manning E. L., Crosland J., Dewey M. J., van Zant G. 2002. Influence of inbreeding and genetics on telomere length in mice. Mamm. Genome. 13, 234-238.
    • (2002) Mamm. Genome. , vol.13 , pp. 234-238
    • Manning, E.L.1    Crosland, J.2    Dewey, M.J.3    van Zant, G.4
  • 142
    • 79953147386 scopus 로고    scopus 로고
    • RTEL1: An essential helicase for telomere maintenance and the regulation of homologous recombination
    • Uringa E.-J., Youds J. L., Lisaingo K., Lansdorp P. M., Boulton S. J. 2011. RTEL1: An essential helicase for telomere maintenance and the regulation of homologous recombination. Nucleic Acids Res. 39, 1647-1655.
    • (2011) Nucleic Acids Res , vol.39 , pp. 1647-1655
    • Uringa, E.-J.1    Youds, J.L.2    Lisaingo, K.3    Lansdorp, P.M.4    Boulton, S.J.5
  • 143
    • 0027993344 scopus 로고
    • Genetic determination of telomere size in humans: A twin study of three age groups
    • Slagboom P. E., Droog S., Boomsma D. I. 1994. Genetic determination of telomere size in humans: A twin study of three age groups. Am. J. Hum. Genet. 55, 876-882.
    • (1994) Am. J. Hum. Genet. , vol.55 , pp. 876-882
    • Slagboom, P.E.1    Droog, S.2    Boomsma, D.I.3
  • 144
    • 33744503149 scopus 로고    scopus 로고
    • The pattern of chromosome-specific variations in telomere length in humans shows signs of heritability and is maintained through life
    • Graakjaer J., Londono-Vallejo J. A., Christensen K., Kolvraa S. 2006. The pattern of chromosome-specific variations in telomere length in humans shows signs of heritability and is maintained through life. Ann. N. Y. Acad. Sci. 1067, 311-316.
    • (2006) Ann. N.Y. Acad. Sci. , vol.1067 , pp. 311-316
    • Graakjaer, J.1    Londono-Vallejo, J.A.2    Christensen, K.3    Kolvraa, S.4
  • 148
    • 70350001509 scopus 로고    scopus 로고
    • OB foldcontaining protein 1 (OBFC1), a human homolog of yeast Stn1, associates with TPP1 and is implicated in telomere length regulation
    • Wan M., Qin J., Songyang Z., Liu D. J. 2009. OB foldcontaining protein 1 (OBFC1), a human homolog of yeast Stn1, associates with TPP1 and is implicated in telomere length regulation. Biol. Chem. 284, 26725-26731.
    • (2009) Biol. Chem. , vol.284 , pp. 26725-26731
    • Wan, M.1    Qin, J.2    Songyang, Z.3    Liu, D.J.4
  • 150
    • 70349815091 scopus 로고    scopus 로고
    • Short telomeres resulting from heritable mutations in the telomerase reverse transcriptase gene predispose for a variety of malignancies
    • Hills M., Lansdorp P. M. 2009. Short telomeres resulting from heritable mutations in the telomerase reverse transcriptase gene predispose for a variety of malignancies. Ann. N. Y. Acad. Sci. 1176, 178-190.
    • (2009) Ann. N. Y. Acad. Sci. , vol.1176 , pp. 178-190
    • Hills, M.1    Lansdorp, P.M.2
  • 152
    • 0029040101 scopus 로고
    • Developmental and tissue-specific regulation of mouse telomerase and telomere length
    • Prowse K. R., Greider C. W. 1995. Developmental and tissue-specific regulation of mouse telomerase and telomere length. Proc. Natl. Acad. Sci. U. S. A. 92, 4818-4822.
    • (1995) Proc. Natl. Acad. Sci. U. S. A. , vol.92 , pp. 4818-4822
    • Prowse, K.R.1    Greider, C.W.2
  • 153
    • 58149341744 scopus 로고    scopus 로고
    • Coevolution of telomerase activity and body mass in mammals: From mice to beavers
    • Gorbunova V., Seluanov A. 2009. Coevolution of telomerase activity and body mass in mammals: From mice to beavers. Mech. Ageing Dev. 130, 3-9.
    • (2009) Mech. Ageing Dev. , vol.130 , pp. 3-9
    • Gorbunova, V.1    Seluanov, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.