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Volumn 256, Issue 21-22, 2012, Pages 2478-2487

Electron hopping through proteins

Author keywords

DNA photolyase; Electron transfer; Hopping maps; MauG; Multistep tunneling; Redox proteins azurin; Ribonucleotide reductase

Indexed keywords


EID: 84866390958     PISSN: 00108545     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ccr.2012.03.032     Document Type: Review
Times cited : (152)

References (92)
  • 10
    • 0004053611 scopus 로고    scopus 로고
    • For a general description of complexes I-IV, ATP, synthase see:, John Wiley and Sons, Hoboken, NJ
    • Voet D.G., Voet J.G. Biochemistry 2011, For a general description of complexes I-IV, ATP, synthase see:, John Wiley and Sons, Hoboken, NJ. 4th ed.
    • (2011) Biochemistry
    • Voet, D.G.1    Voet, J.G.2
  • 23
    • 79959463001 scopus 로고    scopus 로고
    • See, for example
    • Wenger O.S. Chem. Soc. Rev. 2011, 40:3538. See, for example:.
    • (2011) Chem. Soc. Rev. , vol.40 , pp. 3538
    • Wenger, O.S.1
  • 28
    • 84866365012 scopus 로고    scopus 로고
    • Wolfram Research, Inc., Mathematica, Version 7.0, Champaign, IL
    • Wolfram Research, Inc., Mathematica, Version 7.0, Champaign, IL, 2008.
    • (2008)
  • 29
    • 84866365013 scopus 로고    scopus 로고
    • A computer program for the construction of hopping maps is available for download at
    • A computer program for the construction of hopping maps is available for download at http://www.bilrc.caltech.edu/.
  • 36
    • 84866430132 scopus 로고    scopus 로고
    • The average distances used here are arguably a better approximation since the electron comes from (or goes) to a delocalized π-system in Trp. The distances used in the original study [9] are the Trp-C2 to Re (or Cu) distances; r1=8.9Å, r2=11.1Å and rT=19.4Å.
    • The average distances used here are arguably a better approximation since the electron comes from (or goes) to a delocalized π-system in Trp. The distances used in the original study [9] are the Trp-C2 to Re (or Cu) distances; r1=8.9Å, r2=11.1Å and rT=19.4Å.
  • 37
    • 84866365010 scopus 로고    scopus 로고
    • E°(ReI*/0)=1.25V. J.J. Warren, H.B. Gray, Work in progress.
    • E°(ReI*/0)=1.25V. J.J. Warren, H.B. Gray, Work in progress.
  • 65
    • 84866430133 scopus 로고    scopus 로고
    • Note that these average distances might better approximate where electrons/holes come from or go to, but they are not rigorously consistent with r0=3Å. Other formulations of ET distances are possible, such as edge-to-edge distances, which are in accord with r0=3Å.
    • Note that these average distances might better approximate where electrons/holes come from or go to, but they are not rigorously consistent with r0=3Å. Other formulations of ET distances are possible, such as edge-to-edge distances, which are in accord with r0=3Å.
  • 73
    • 84866381102 scopus 로고    scopus 로고
    • As noted in Section 3.1, changes in ET distances affect calculated hopping times, which is especially important when dealing with redox systems that include a high valent heme in which a hole is delocalized. Employing ET distances to/from a heme edge, rather than the iron center, will predict faster hopping. It follows that our prediction of a 102-fold rate enhancement in MauG/preMADH likely is a lower limit.
    • As noted in Section 3.1, changes in ET distances affect calculated hopping times, which is especially important when dealing with redox systems that include a high valent heme in which a hole is delocalized. Employing ET distances to/from a heme edge, rather than the iron center, will predict faster hopping. It follows that our prediction of a 102-fold rate enhancement in MauG/preMADH likely is a lower limit.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.