Kinetics of cyclobutane thymine dimer splitting by DNA photolyase directly monitored in the UV

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 23, 2011, Pages 9402-9407

  Thiagarajan, Viruthachalam ^a,b   Byrdin, Martin ^a,c,d   Eker, André P M ^e   Müller, Pavel ^a,f   Brettel, Klaus ^a,c  

^a SERVICE DE CHIMIE BIOORGANIQUE ET DE MARQUAGE   (France)

^b ECOLE NORMALE SUPÉRIEURE   (France)

^c CNRS   (France)

^d INSTITUT DE BIOLOGIE STRUCTURALE   (France)

^e ERASMUS MEDICAL CENTER   (Netherlands)

^f SORBONNE UNIVERSITÉ   (France)

Author keywords

DNA repair; Flavin adenine dinucleotide; Transient absorption spectroscopy; UV damage

Indexed keywords

CYCLOBUTANE DERIVATIVE; CYCLOBUTANE THYMINE; DEOXYRIBODIPYRIMIDINE PHOTOLYASE; DIMER; FLAVINE ADENINE NUCLEOTIDE; QUERCETIN; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL BOND; CYANOBACTERIUM; DNA REPAIR; ELECTRON TRANSPORT; ESCHERICHIA COLI; HETEROLOGOUS EXPRESSION; KINETICS; NONHUMAN; PHOTOREACTIVITY; PHOTORECEPTOR; PRIORITY JOURNAL; RADIATION ABSORPTION; ULTRAVIOLET RADIATION;

EID: 79959343622     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1101026108     Document Type: Article

References (23)

1. Sancar A (2003) Structure and function of DNA photolyase and cryptochrome blue-light photoreceptors. Chem Rev 103:2203-2237.
2. Brettel K, Byrdin M (2010) Reaction mechanisms of DNA photolyase. Curr Opin Struct Biol 20:693-701.
3. Dalhus B, Laerdahl JK, Backe PH, Bjørås M (2009) DNA base repair - recognition and initiation of catalysis. FEMS Microbiol Rev 33:1044-1078.
4. Eker APM, Quayle C, Chaves I, van der Horst GTJ (2009) Direct DNA damage reversal: elegant solutions for nasty problems. Cell Mol Life Sci 66:968-980.
5. Peng W, Shaw BR (1996) Accelerated deamination of cytosine residues in UV-induced cyclobutane pyrimidine dimers leads to CC → TT transitions. Biochemistry 35:10172-10181. (Pubitemid 26269935)
6. Kao YT, Saxena C, Wang L, Sancar A, Zhong D (2005) Direct observation of thymine dimer repair in DNA by photolyase. Proc Natl Acad Sci USA 102:16128-16132. (Pubitemid 41688879)
7. Espagne A, Byrdin M, Eker APM, Brettel K (2009) Very fast product release and catalytic turnover of DNA photolyase. Chembiochem 10:1777-1780.
8. Thiagarajan V, et al. (2010) DNA repair by photolyase: A novel substrate with low background absorption around 265 nm for transient absorption studies in the UV. Biochemistry 49:297-303.
9. MacFarlane AW, Stanley RJ (2003) Cis-syn thymidine dimer repair by DNA photolyase in real time. Biochemistry 42:8558-8568.
10. Mees A, et al. (2004) Crystal structure of a photolyase bound to a CPD-like DNA lesion after in situ repair. Science 306:1789-1793. (Pubitemid 39601399)
11. Masson F, Laino T, Rothlisberger U, Hutter JA (2009) QM/MM investigation of thymine dimer radical anion splitting catalyzed by DNA photolyase. Chemphyschem 10:400-410.
12. Byrdin M, Thiagarajan V, Villette S, Espagne A, Brettel K (2009) Use of ruthenium dyes for subnanosecond detector fidelity testing in real time transient absorption. Rev Sci Instrum 80:043102.
13. Okamura T, et al. (1991) Picosecond laser photolysis studies on the photorepair of pyrimidine dimers by DNA photolyase. 1. Laser photolysis of photolyase-2-deoxyuridine dinucleotide photodimer complex. J Am Chem Soc 113:3143-3145.
14. Chatgilialoglu C, et al. (2007) Ring opening of the cyclobutane in a thymine dimer radical anion. Chem Eur J 13:8979-8984. (Pubitemid 350097697)
15. Li J, et al. (2010) Dynamics and mechanism of repair of ultraviolet-induced (6-4) photoproduct by photolyase. Nature 466:887-890.
16. Kumar A, Sevilla MD (2010) Proton-coupled electron transfer in DNA on formation of radiation-produced ion radicals. Chem Rev 110:7002-7023.
17. Boussicault F, Krüger O, Robert M, Wille U (2004) Dissociative electron transfer to and from pyrimidine cyclobutane dimers: An electrochemical study. Org Biomol Chem 2:2742-2750.
18. Kim ST, Sancar A (1991) Effect of base, pentose, and phosphodiester backbone structures on binding and repair of pyrimidine dimers by Escherichia coli DNA photolyase. Biochemistry 30:8623-30.
19. Murphy AK, Tammaro M, Cortazar F, Gindt YM, Schelvis JPM (2008) Effect of the cyclobutane cytidine dimer on the properties of Escherichia coli DNA photolyase. J Phys Chem B 112:15217-15226.
20. Pac C, Kubo J, Majima T, Sakurai H (1982) Structure-reactivity relationships in redox-photosensitized splitting of pyrimidine dimers and unusual enhancing effect of molecular oxygen. Photochem Photobiol 36:273-282.
21. Yeh SR, Falvey DE (1992) Model studies of DNA photorepair: Energetic requirements for the radical anion mechanism determined by fluorescence quenching. J Am Chem Soc 114:7313-7314.
22. Malhotra K, Kim S-T, Walsh C, Sancar A (1992) Roles of FAD and 8-hydroxy-5-deazaflavin chromophores in photoreactivation by Anacystis nidulans DNA photolyase. J Biol Chem 267:15406-154011.
23. Jorns MS, Wang BY, Jordan SP, Chanderkar LP (1990) Chromophore function and interaction in Escherichia coli DNA photolyase: Reconstitution of the apoenzyme with pterin and/or flavin derivatives. Biochemistry 29:552-561. (Pubitemid 20037664)