Incorporation of fluorotyrosines into ribonucleotide reductase using an evolved, polyspecific aminoacyl-tRNA synthetase

Journal of the American Chemical Society

Volumn 133, Issue 40, 2011, Pages 15942-15945

  Minnihan, Ellen C ^a   Young, Douglas D ^b   Schultz, Peter G ^b   Stubbe, Joanne ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL CATALYSIS; DIRECTED EVOLUTION; ELECTRON PARAMAGNETIC RESONANCE SPECTROSCOPY; GOOD YIELD; HIGH SPECIFICITY; PEAK POTENTIALS; PHYSIOLOGICAL CONDITION; RADICAL PATHWAY; RIBONUCLEOTIDE REDUCTASE; SPECTRAL SUBTRACTIONS; SYNTHETASES; TYROSYL RADICALS; WILD TYPES;

AMINO ACIDS; BIOLOGY; CATALYSIS; ELECTRON SPIN RESONANCE SPECTROSCOPY; ENZYME ACTIVITY; ESCHERICHIA COLI; PARAMAGNETISM;

PARAMAGNETIC RESONANCE;

FLUOROTYROSINE; PROTON; RADICAL; RIBONUCLEOTIDE REDUCTASE; TRANSFER RNA; TYROSINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; ELECTRON; ELECTRON SPIN RESONANCE; ENZYME ACTIVITY; ESCHERICHIA COLI; NONHUMAN; PH;

AMINO ACYL-TRNA SYNTHETASES; ELECTRON SPIN RESONANCE SPECTROSCOPY; ESCHERICHIA COLI; HALOGENATION; METHANOCOCCUS; MODELS, MOLECULAR; RIBONUCLEOTIDE REDUCTASES; TYROSINE;

EID: 80053467272     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja207719f     Document Type: Article

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