Identification of a functionally critical GXXG motif and its relationship to the folate binding site of the proton-coupled folate transporter (PCFT-SLC46A1)

American Journal of Physiology - Cell Physiology

Volumn 303, Issue 6, 2012, Pages

  Zhao, Rongbao ^a   Shin, Daniel Sanghoon ^a   Fiser, Andras ^a   David Goldman, I ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Heme carrier protein 1; Homology modeling; Intestinal folate transport

Indexed keywords

ALANINE; CYSTEINE; FOLIC ACID; GLYCINE; MUTANT PROTEIN; PROTON COUPLED FOLATE TRANSPORTER; THIOL DERIVATIVE;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING SITE; CELL LINE; CONTROLLED STUDY; CROSS LINKING; DIMERIZATION; MOLECULAR MODEL; MUTATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN MOTIF; PROTEIN STRUCTURE; SEQUENCE ALIGNMENT; STRUCTURAL HOMOLOGY; STRUCTURE ACTIVITY RELATION; TEMPERATURE;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; BINDING SITES; CONSERVED SEQUENCE; FOLIC ACID; GLYCINE; HELA CELLS; HUMANS; ISOLEUCINE; MOLECULAR SEQUENCE DATA; PROTEIN TRANSPORT; PROTON-COUPLED FOLATE TRANSPORTER; PROTONS; SIGNAL TRANSDUCTION;

EID: 84866352751     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00123.2012     Document Type: Article

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