Hypermethylation of the human proton-coupled folate transporter (SLC46A1) minimal trancriptional regulatory region in an antifolate-resistant HeLa cell line

Molecular Cancer Therapeutics

Volumn 8, Issue 8, 2009, Pages 2424-2431

  Diop Bove, Ndeye Khady ^a   Wu, Julia ^a   Zhao, Rongbao ^a   Locker, Joseph ^a   Goldman, I David ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; BISULFITE; CARRIER PROTEIN; FOLIC ACID; LUCIFERASE; MESSENGER RNA; METHOTREXATE; NUCLEOTIDE; PROTON COUPLED FOLATE TRANSPORTER; UNCLASSIFIED DRUG;

ARTICLE; CANCER RESISTANCE; CELL TRANSPORT; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; ENZYME ACTIVITY; FLUORESCENCE IN SITU HYBRIDIZATION; GENE; GENE EXPRESSION; GENE LOSS; HELA CELL; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PCFT GENE; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN METHYLATION; REPORTER GENE; SEQUENCE ANALYSIS; TRANSCRIPTION REGULATION; TRANSIENT TRANSFECTION; TRANSLATION REGULATION; WILD TYPE;

BASE SEQUENCE; DRUG RESISTANCE, NEOPLASM; FOLIC ACID ANTAGONISTS; HELA CELLS; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; MEMBRANE TRANSPORT PROTEINS; METHYLATION; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS, GENETIC; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 68849117681     PISSN: 15357163     EISSN: None     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-08-0938     Document Type: Article

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