Properties of the Arg376 residue of the proton-coupled folate transporter (PCFT-SLC46A1) and a glutamine mutant causing hereditary folate malabsorption

American Journal of Physiology - Cell Physiology

Volumn 299, Issue 5, 2010, Pages

  Mahadeo, Kris ^a   Diop Bove, Ndeye ^a   Shin, Daniel ^a   Unal, Ersin Selcuk ^a,d   Teo, Juliana ^b   Zhao, Rongbao ^a   Chang, Min Hwang ^c   Fulterer, Andreas ^c   Romero, Michael F ^c   Goldman, I David ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b CHILDREN S HOSPITAL AT WESTMEAD   (Australia)

^c MAYO GRADUATE SCHOOL   (United States)

^d ISTANBUL UNIVERSITY   (Turkey)

Author keywords

Choroid plexus; Folate deficiency; Folate receptors; Folate transport; Heme carrier protein 1; Intestinal folate absorption; Reduced folate carrier

Indexed keywords

5 METHYLTETRAHYDROFOLIC ACID; CARRIER PROTEIN; FOLIC ACID; FOLINIC ACID; MUTANT PROTEIN; PEMETREXED; PROTEIN PCFT; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; ELECTROPHYSIOLOGY; MALABSORPTION; OOCYTE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; XENOPUS;

AMINO ACID SUBSTITUTION; ANIMALS; ARGININE; FOLIC ACID; FOLIC ACID ANTAGONISTS; GLUTAMATES; GLUTAMINE; GUANINE; HELA CELLS; HUMANS; HYDROGEN-ION CONCENTRATION; MALABSORPTION SYNDROMES; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OOCYTES; PATCH-CLAMP TECHNIQUES; PROTON-COUPLED FOLATE TRANSPORTER; PROTONS; TETRAHYDROFOLATES; XENOPUS LAEVIS;

EID: 78349241039     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00113.2010     Document Type: Article

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