Transporter-associated currents in the γ-aminobutyric acid transporter GAT-1 are conditionally impaired by mutations of a conserved glycine residue

Journal of Biological Chemistry

Volumn 280, Issue 21, 2005, Pages 20316-20324

  Zhou, Yonggang ^a   Kanner, Baruch I ^a  

^a HEBREW UNIVERSITY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

CONFORMATIONS; LITHIUM; MUTAGENESIS; ORGANIC ACIDS; SODIUM;

CONFORMATIONAL CHANGES; DEPOLARIZATION; GLYCINE; MUTANTS;

NEUROLOGY;

4 AMINOBUTYRIC ACID; CARRIER PROTEIN; CYSTEINE; GLYCINE; LITHIUM; PROTEIN GAT 1; UNCLASSIFIED DRUG;

4 AMINOBUTYRIC ACID UPTAKE; ARTICLE; CELL MEMBRANE DEPOLARIZATION; CONFORMATIONAL TRANSITION; GABAERGIC TRANSMISSION; HUMAN; HUMAN CELL; MUTATION; OOCYTE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN TRANSPORT; SITE DIRECTED MUTAGENESIS; SODIUM CURRENT;

ANIMALS; BIOTINYLATION; CONSERVED SEQUENCE; CYSTEINE; ELECTRIC CONDUCTIVITY; FEMALE; GABA PLASMA MEMBRANE TRANSPORT PROTEINS; GAMMA-AMINOBUTYRIC ACID; GENE EXPRESSION; GLYCINE; HELA CELLS; HUMANS; LITHIUM; MEMBRANE TRANSPORT PROTEINS; MESYLATES; MUTAGENESIS, SITE-DIRECTED; OOCYTES; PROTEIN CONFORMATION; RNA, COMPLEMENTARY; SODIUM; STRUCTURE-ACTIVITY RELATIONSHIP; SULFHYDRYL REAGENTS; TRANSFECTION; TRITIUM; XENOPUS LAEVIS;

EID: 20144378948     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M412937200     Document Type: Article

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