Hereditary folate malabsorption: A positively charged amino acid at position 113 of the proton-coupled folate transporter (PCFT/SLC46A1) is required for folic acid binding

Biochemical and Biophysical Research Communications

Volumn 386, Issue 3, 2009, Pages 426-431

  Lasry, Inbal ^a   Berman, Bluma ^a   Glaser, Fabian ^a   Jansen, Gerrit ^b   Assaraf, Yehuda G ^a  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Folates; Hereditary folate malabsorption; Intestinal folate transport; Loss of function mutations; PCFT

Indexed keywords

CARRIER PROTEIN; FOLIC ACID; GLYCEROPHOSPHATE; PROTON COUPLED FOLATE TRANSPORTER; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; CRYSTAL STRUCTURE; ESCHERICHIA COLI; MALABSORPTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN STRUCTURE; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; ARGININE; FOLIC ACID; HUMANS; INTESTINAL ABSORPTION; MALABSORPTION SYNDROMES; MEMBRANE TRANSPORT PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN CONFORMATION;

ESCHERICHIA COLI;

EID: 67650047730     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.06.007     Document Type: Article

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