-
1
-
-
33746342994
-
Foxp3+ CD25+ CD4+ natural regulatory T cells in dominant self-tolerance and autoimmune disease
-
Sakaguchi S, Ono M, Setoguchi R, Yagi H, Hori S, et al. (2006) Foxp3+ CD25+ CD4+ natural regulatory T cells in dominant self-tolerance and autoimmune disease. Immunol Rev 212: 8-27.
-
(2006)
Immunol Rev
, vol.212
, pp. 8-27
-
-
Sakaguchi, S.1
Ono, M.2
Setoguchi, R.3
Yagi, H.4
Hori, S.5
-
2
-
-
0037364976
-
Regulatory T cells in transplantation tolerance
-
Wood KJ, Sakaguchi S, (2003) Regulatory T cells in transplantation tolerance. Nat Rev Immunol 3: 199-210.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 199-210
-
-
Wood, K.J.1
Sakaguchi, S.2
-
3
-
-
78651396992
-
Comprehensive analysis of frequency and phenotype of T regulatory cells in HIV infection: CD39 expression of FoxP3+ T regulatory cells correlates with progressive disease
-
Schulze Zur Wiesch J, Thomssen A, Hartjen P, Tóth I, Lehmann C, et al. (2011) Comprehensive analysis of frequency and phenotype of T regulatory cells in HIV infection: CD39 expression of FoxP3+ T regulatory cells correlates with progressive disease. J Virol 85: 1287-1297.
-
(2011)
J Virol
, vol.85
, pp. 1287-1297
-
-
Schulze Zur Wiesch, J.1
Thomssen, A.2
Hartjen, P.3
Tóth, I.4
Lehmann, C.5
-
4
-
-
44749092510
-
Regulatory T cells and treatment of cancer
-
Curiel TJ, (2008) Regulatory T cells and treatment of cancer. Curr Opin Immunol 20: 241-246.
-
(2008)
Curr Opin Immunol
, vol.20
, pp. 241-246
-
-
Curiel, T.J.1
-
5
-
-
77955411096
-
Success or failure of vaccination for HPV16-positive vulvar lesions correlates with kinetics and phenotype of induced T-cell responses
-
Welters MJ, Kenter GG, de Vos van Steenwijk PJ, Löwik MJ, Berends-van der Meer DM, et al. (2010) Success or failure of vaccination for HPV16-positive vulvar lesions correlates with kinetics and phenotype of induced T-cell responses. Proc Natl Acad Sci U S A 107: 11895-11899.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 11895-11899
-
-
Welters, M.J.1
Kenter, G.G.2
de Vos van Steenwijk, P.J.3
Löwik, M.J.4
Berends-van der Meer, D.M.5
-
6
-
-
65549127618
-
Human T regulatory cells as therapeutic agents: Take a billion or so of these and call me in the morning
-
Riley JL, June CH, Blazar BR, (2009) Human T regulatory cells as therapeutic agents: Take a billion or so of these and call me in the morning. Immunity 30: 656-665.
-
(2009)
Immunity
, vol.30
, pp. 656-665
-
-
Riley, J.L.1
June, C.H.2
Blazar, B.R.3
-
7
-
-
33748416499
-
Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412
-
Shuntharalingam G, Perry MR, Ward S, Brett SJ, Castello-Cortes A, et al. (2006) Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412. N Engl J Med 355: 1018-1028.
-
(2006)
N Engl J Med
, vol.355
, pp. 1018-1028
-
-
Shuntharalingam, G.1
Perry, M.R.2
Ward, S.3
Brett, S.J.4
Castello-Cortes, A.5
-
8
-
-
44849118898
-
Clinical application of regulatory T cells for treatment of type 1 diabetes and transplantation
-
Brusko T, Bluestone J, (2008) Clinical application of regulatory T cells for treatment of type 1 diabetes and transplantation. Eur J Immunol 38: 931-934.
-
(2008)
Eur J Immunol
, vol.38
, pp. 931-934
-
-
Brusko, T.1
Bluestone, J.2
-
9
-
-
62749201002
-
Expansion of human regulatory T-cells from patients with type 1 diabetes
-
Putnam AL, Brusko TM, Lee MR, Liu W, Szot GL, et al. (2009) Expansion of human regulatory T-cells from patients with type 1 diabetes. Diabetes 58: 652-662.
-
(2009)
Diabetes
, vol.58
, pp. 652-662
-
-
Putnam, A.L.1
Brusko, T.M.2
Lee, M.R.3
Liu, W.4
Szot, G.L.5
-
10
-
-
80052869960
-
Immune intervention with T regulatory cells: past lessons and future perspectives for type 1 diabetes
-
Battaglia M, Roncarolo MG, (2011) Immune intervention with T regulatory cells: past lessons and future perspectives for type 1 diabetes. Semin Immunol 23: 182-194.
-
(2011)
Semin Immunol
, vol.23
, pp. 182-194
-
-
Battaglia, M.1
Roncarolo, M.G.2
-
11
-
-
52449099834
-
Interferon-gamma conditioning ex vivo generates CD25+CD62L+Foxp3+ regulatory T cells that prevent allograft rejection: potential avenues for cellular therapy
-
Feng G, Wood KJ, Bushell A, (2008) Interferon-gamma conditioning ex vivo generates CD25+CD62L+Foxp3+ regulatory T cells that prevent allograft rejection: potential avenues for cellular therapy. Transplantation 86: 578-589.
-
(2008)
Transplantation
, vol.86
, pp. 578-589
-
-
Feng, G.1
Wood, K.J.2
Bushell, A.3
-
12
-
-
84856908569
-
CD4(+)Foxp3(+) regulatory T cell therapy in transplantation
-
Tang Q, Bluestone JA, Kang SM, (2012) CD4(+)Foxp3(+) regulatory T cell therapy in transplantation. J Mol Cell Biol 4: 11-21.
-
(2012)
J Mol Cell Biol
, vol.4
, pp. 11-21
-
-
Tang, Q.1
Bluestone, J.A.2
Kang, S.M.3
-
13
-
-
80053597291
-
Regulatory T cells in stem cell transplantation: strategies and first clinical experiences
-
Edinger M, Hoffmann P, (2011) Regulatory T cells in stem cell transplantation: strategies and first clinical experiences. Curr Opin Immunol 23: 679-684.
-
(2011)
Curr Opin Immunol
, vol.23
, pp. 679-684
-
-
Edinger, M.1
Hoffmann, P.2
-
14
-
-
48849099425
-
Directing T cell differentiation and function with small molecule inhibitors
-
Bruno L, Merkenschlager M, (2008) Directing T cell differentiation and function with small molecule inhibitors. Cell Cycle 7: 2296-2298.
-
(2008)
Cell Cycle
, vol.7
, pp. 2296-2298
-
-
Bruno, L.1
Merkenschlager, M.2
-
15
-
-
47249124078
-
Human regulatory T cells: role in autoimmune disease and therapeutic opportunities
-
Brusko TM, Putnam AL, Bluestone JA, (2008) Human regulatory T cells: role in autoimmune disease and therapeutic opportunities. Immunol Rev 223: 371-390.
-
(2008)
Immunol Rev
, vol.223
, pp. 371-390
-
-
Brusko, T.M.1
Putnam, A.L.2
Bluestone, J.A.3
-
16
-
-
63849333830
-
Altering regulatory T cell function in cancer immunotherapy: a novel means to boost the efficacy of cancer vaccines
-
Ruter J, Barnett BG, Kryczek I, Brumlik MJ, Daniel BJ, et al. (2009) Altering regulatory T cell function in cancer immunotherapy: a novel means to boost the efficacy of cancer vaccines. Front Biosci 14: 1761-1770.
-
(2009)
Front Biosci
, vol.14
, pp. 1761-1770
-
-
Ruter, J.1
Barnett, B.G.2
Kryczek, I.3
Brumlik, M.J.4
Daniel, B.J.5
-
18
-
-
34547629044
-
Interleukin-2 administration alters the CD4+FOXP3+ T-cell pool and tumor trafficking in patients with ovarian carcinoma
-
Wei S, Kryczek I, Edwards RP, Zou L, Szeliga W, et al. (2007) Interleukin-2 administration alters the CD4+FOXP3+ T-cell pool and tumor trafficking in patients with ovarian carcinoma. Cancer Res 67: 7487-7494.
-
(2007)
Cancer Res
, vol.67
, pp. 7487-7494
-
-
Wei, S.1
Kryczek, I.2
Edwards, R.P.3
Zou, L.4
Szeliga, W.5
-
19
-
-
77954953523
-
Increase of circulating CD4+CD25highFoxp3+ regulatory T cells in patients with metastatic renal cell carcinoma during treatment with dendritic cell vaccination and low-dose interleukin-2
-
Berntsen A, Brimnes MK, thor Straten P, Svane IM, (2010) Increase of circulating CD4+CD25highFoxp3+ regulatory T cells in patients with metastatic renal cell carcinoma during treatment with dendritic cell vaccination and low-dose interleukin-2. J Immunother 33: 425-434.
-
(2010)
J Immunother
, vol.33
, pp. 425-434
-
-
Berntsen, A.1
Brimnes, M.K.2
thor Straten, P.3
Svane, I.M.4
-
20
-
-
84856039913
-
In vivo expansion of naive CD4+ CD25(high) FOXP3+ regulatory T cells in patients with colorectal carcinoma after IL-2 administration
-
Beyer M, Schumak B, Weihrauch MR, Andres B, Giese T, et al. (2012) In vivo expansion of naive CD4+ CD25(high) FOXP3+ regulatory T cells in patients with colorectal carcinoma after IL-2 administration. PLoS One 7: e30422.
-
(2012)
PLoS One
, vol.7
-
-
Beyer, M.1
Schumak, B.2
Weihrauch, M.R.3
Andres, B.4
Giese, T.5
-
21
-
-
79954559096
-
T-cell tolerance and the multi-functional role of IL-2R signaling in T-regulatory cells
-
Cheng G, Yu A, Malek TR, (2011) T-cell tolerance and the multi-functional role of IL-2R signaling in T-regulatory cells. Immunol Rev 241: 63-76.
-
(2011)
Immunol Rev
, vol.241
, pp. 63-76
-
-
Cheng, G.1
Yu, A.2
Malek, T.R.3
-
22
-
-
78650668123
-
Cutting edge: mechanisms of IL-2-dependent maintenance of functional regulatory T cells
-
Barron L, Dooms H, Hoyer KK, Kuswanto W, Hofmann J, et al. (2010) Cutting edge: mechanisms of IL-2-dependent maintenance of functional regulatory T cells. J Immunol 185: 6426-6430.
-
(2010)
J Immunol
, vol.185
, pp. 6426-6430
-
-
Barron, L.1
Dooms, H.2
Hoyer, K.K.3
Kuswanto, W.4
Hofmann, J.5
-
23
-
-
33748500819
-
The structure of IL2 bound to the three chains of the IL2 receptor and how signaling occurs
-
Smith KA, (2006) The structure of IL2 bound to the three chains of the IL2 receptor and how signaling occurs. Med Immunol 5: 3.
-
(2006)
Med Immunol
, vol.5
, pp. 3
-
-
Smith, K.A.1
-
24
-
-
27944505913
-
Structure of the quaternary complex of interleukin-2 with its alpha, beta, and gammac receptors
-
Wang X, Rickert M, Garcia KC, (2005) Structure of the quaternary complex of interleukin-2 with its alpha, beta, and gammac receptors. Science 310: 1159-1163.
-
(2005)
Science
, vol.310
, pp. 1159-1163
-
-
Wang, X.1
Rickert, M.2
Garcia, K.C.3
-
25
-
-
33644540157
-
Crystal structure of the IL-2 signaling complex: paradigm for a heterotrimeric cytokine receptor
-
Stauber DJ, Debler EW, Horton PA, Smith KA, Wilson IA, (2006) Crystal structure of the IL-2 signaling complex: paradigm for a heterotrimeric cytokine receptor. Proc Natl Acad Sci U S A 103: 2788-2793.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 2788-2793
-
-
Stauber, D.J.1
Debler, E.W.2
Horton, P.A.3
Smith, K.A.4
Wilson, I.A.5
-
26
-
-
0036839102
-
Homeostasis of peripheral CD4+ T cells: IL-2R alpha and IL-2 shape a population of regulatory cells that controls CD4+ T cell numbers
-
Almeida AR, Legrand N, Papiernik M, Freitas AA, (2002) Homeostasis of peripheral CD4+ T cells: IL-2R alpha and IL-2 shape a population of regulatory cells that controls CD4+ T cell numbers. J Immunol 169: 4850-4860.
-
(2002)
J Immunol
, vol.169
, pp. 4850-4860
-
-
Almeida, A.R.1
Legrand, N.2
Papiernik, M.3
Freitas, A.A.4
-
27
-
-
0036669298
-
CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2
-
Malek TR, Yu A, Vincek V, Scibelli P, Kong L, (2002) CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2. Immunity 17: 167-178.
-
(2002)
Immunity
, vol.17
, pp. 167-178
-
-
Malek, T.R.1
Yu, A.2
Vincek, V.3
Scibelli, P.4
Kong, L.5
-
28
-
-
7144259082
-
Regulatory CD4 T cells: expression of IL-2R alpha chain, resistance to clonal deletion and IL-2 dependency
-
Papiernik M, de Moraes ML, Pontoux C, Vasseur F, Pénit C, (1998) Regulatory CD4 T cells: expression of IL-2R alpha chain, resistance to clonal deletion and IL-2 dependency. Int Immunol 10: 371-378.
-
(1998)
Int Immunol
, vol.10
, pp. 371-378
-
-
Papiernik, M.1
de Moraes, M.L.2
Pontoux, C.3
Vasseur, F.4
Pénit, C.5
-
29
-
-
34447572680
-
IL-2Rbeta links IL-2R signaling with Foxp3 expression
-
Soper DM, Kasprowicz DJ, Ziegler SF, (2007) IL-2Rbeta links IL-2R signaling with Foxp3 expression. Eur J Immunol 37: 1817-1826.
-
(2007)
Eur J Immunol
, vol.37
, pp. 1817-1826
-
-
Soper, D.M.1
Kasprowicz, D.J.2
Ziegler, S.F.3
-
30
-
-
0028783963
-
Generalized autoimmune disease in interleukin-2-deficient mice is triggered by an uncontrolled activation and proliferation of CD4+ T cells
-
Sadlack B, Löhler J, Schorle H, Klebb G, Haber H, et al. (1995) Generalized autoimmune disease in interleukin-2-deficient mice is triggered by an uncontrolled activation and proliferation of CD4+ T cells. Eur J Immunol 25: 3053-3059.
-
(1995)
Eur J Immunol
, vol.25
, pp. 3053-3059
-
-
Sadlack, B.1
Löhler, J.2
Schorle, H.3
Klebb, G.4
Haber, H.5
-
31
-
-
0029028363
-
Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta
-
Suzuki H, Kündig TM, Furlonger C, Wakeham A, Timms E, et al. (1995) Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta. Science 268: 1472-1476.
-
(1995)
Science
, vol.268
, pp. 1472-1476
-
-
Suzuki, H.1
Kündig, T.M.2
Furlonger, C.3
Wakeham, A.4
Timms, E.5
-
32
-
-
0028784289
-
Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment
-
Willerford DM, Chen J, Ferry JA, Davidson L, Ma A, et al. (1995) Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment. Immunity 3: 521-530.
-
(1995)
Immunity
, vol.3
, pp. 521-530
-
-
Willerford, D.M.1
Chen, J.2
Ferry, J.A.3
Davidson, L.4
Ma, A.5
-
33
-
-
15544384475
-
Essential role for interleukin-2 for CD4(+)CD25(+) T regulatory cell development during the neonatal period
-
Bayer AL, Yu A, Adeegbe D, Malek TR, (2005) Essential role for interleukin-2 for CD4(+)CD25(+) T regulatory cell development during the neonatal period. J Exp Med 201: 769-777.
-
(2005)
J Exp Med
, vol.201
, pp. 769-777
-
-
Bayer, A.L.1
Yu, A.2
Adeegbe, D.3
Malek, T.R.4
-
34
-
-
0348047537
-
The main function of IL-2 is to promote the development of T regulatory cells
-
Malek TR, (2003) The main function of IL-2 is to promote the development of T regulatory cells. J Leukoc Biol 74: 961-965.
-
(2003)
J Leukoc Biol
, vol.74
, pp. 961-965
-
-
Malek, T.R.1
-
35
-
-
0037120053
-
Interleukin 2 signaling is required for CD4(+) regulatory T cell function
-
Furtado GC, Curotto de Lafaille MA, Kutchukhidze N, Lafaille JJ, (2002) Interleukin 2 signaling is required for CD4(+) regulatory T cell function. J Exp Med 196: 851-857.
-
(2002)
J Exp Med
, vol.196
, pp. 851-857
-
-
Furtado, G.C.1
Curotto de Lafaille, M.A.2
Kutchukhidze, N.3
Lafaille, J.J.4
-
36
-
-
33749524594
-
Selective availability of IL-2 is a major determinant controlling the production of CD4+CD25+Foxp3+ T regulatory cells
-
Yu A, Malek TR, (2006) Selective availability of IL-2 is a major determinant controlling the production of CD4+CD25+Foxp3+ T regulatory cells. J Immunol 177: 5115-5121.
-
(2006)
J Immunol
, vol.177
, pp. 5115-5121
-
-
Yu, A.1
Malek, T.R.2
-
37
-
-
15444374646
-
Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization
-
Setoguchi R, Hori S, Takahashi T, Sakaguchi S, (2005) Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization. J Exp Med 201: 723-735.
-
(2005)
J Exp Med
, vol.201
, pp. 723-735
-
-
Setoguchi, R.1
Hori, S.2
Takahashi, T.3
Sakaguchi, S.4
-
38
-
-
43049174722
-
Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction
-
Tang Q, Adams JY, Penaranda C, Melli K, Piaggio E, et al. (2008) Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction. Immunity 28: 687-697.
-
(2008)
Immunity
, vol.28
, pp. 687-697
-
-
Tang, Q.1
Adams, J.Y.2
Penaranda, C.3
Melli, K.4
Piaggio, E.5
-
39
-
-
78650668123
-
Cutting edge: mechanisms of IL-2-dependent maintenance of functional regulatory T cells
-
Barron L, Dooms H, Hoyer KK, Kuswanto W, Hofmann J, et al. (2010) Cutting edge: mechanisms of IL-2-dependent maintenance of functional regulatory T cells. J Immunol 185: 6426-6430.
-
(2010)
J Immunol
, vol.185
, pp. 6426-6430
-
-
Barron, L.1
Dooms, H.2
Hoyer, K.K.3
Kuswanto, W.4
Hofmann, J.5
-
40
-
-
2442637772
-
Cutting edge: IL-2 is critically required for the in vitro activation of CD4+CD25+ T cell suppressor function
-
Thornton AM, Donovan EE, Piccirillo CA, Shevach EM, (2004) Cutting edge: IL-2 is critically required for the in vitro activation of CD4+CD25+ T cell suppressor function. J Immunol 172: 6519-6523.
-
(2004)
J Immunol
, vol.172
, pp. 6519-6523
-
-
Thornton, A.M.1
Donovan, E.E.2
Piccirillo, C.A.3
Shevach, E.M.4
-
41
-
-
4644369302
-
Interleukin-2 is essential for CD4+CD25+ regulatory T cell function
-
de la Rosa M, Rutz S, Dorninger H, Scheffold A, (2004) Interleukin-2 is essential for CD4+CD25+ regulatory T cell function. Eur J Immunol 34: 2480-2488.
-
(2004)
Eur J Immunol
, vol.34
, pp. 2480-2488
-
-
de la Rosa, M.1
Rutz, S.2
Dorninger, H.3
Scheffold, A.4
-
42
-
-
54249117326
-
The influence of IL-2 family cytokines on activation and function of naturally occurring regulatory T cells
-
Wuest TY, Willette-Brown J, Durum SK, Hurwitz AA, (2008) The influence of IL-2 family cytokines on activation and function of naturally occurring regulatory T cells. J Leukoc Biol 84: 973-980.
-
(2008)
J Leukoc Biol
, vol.84
, pp. 973-980
-
-
Wuest, T.Y.1
Willette-Brown, J.2
Durum, S.K.3
Hurwitz, A.A.4
-
43
-
-
0029150110
-
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
-
Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M, (1995) Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol 155: 1151-1164.
-
(1995)
J Immunol
, vol.155
, pp. 1151-1164
-
-
Sakaguchi, S.1
Sakaguchi, N.2
Asano, M.3
Itoh, M.4
Toda, M.5
-
44
-
-
33644508647
-
The dichotomous role of IL-2: tolerance versus immunity
-
Fehérvari Z, Yamaguchi T, Sakaguchi S, (2006) The dichotomous role of IL-2: tolerance versus immunity. Trends Immunol 27: 109-111.
-
(2006)
Trends Immunol
, vol.27
, pp. 109-111
-
-
Fehérvari, Z.1
Yamaguchi, T.2
Sakaguchi, S.3
-
45
-
-
0034965185
-
Control of T cell hyperactivation in IL-2-deficient mice by CD4(+)CD25(-) and CD4(+)CD25(+) T cells: evidence for two distinct regulatory mechanisms
-
Wolf M, Schimpl A, Hünig T, (2001) Control of T cell hyperactivation in IL-2-deficient mice by CD4(+)CD25(-) and CD4(+)CD25(+) T cells: evidence for two distinct regulatory mechanisms. Eur J Immunol 31: 1637-1645.
-
(2001)
Eur J Immunol
, vol.31
, pp. 1637-1645
-
-
Wolf, M.1
Schimpl, A.2
Hünig, T.3
-
46
-
-
79960129382
-
IL-2 production by dendritic cells promotes Foxp3+ regulatory T-cell expansion in autoimmune-resistant NOD congenic mice
-
Sgouroudis E, Kornete M, Piccirillo CA, (2011) IL-2 production by dendritic cells promotes Foxp3+ regulatory T-cell expansion in autoimmune-resistant NOD congenic mice. Autoimmunity 44: 406-414.
-
(2011)
Autoimmunity
, vol.44
, pp. 406-414
-
-
Sgouroudis, E.1
Kornete, M.2
Piccirillo, C.A.3
-
47
-
-
14744291244
-
CD40/CD40L interaction regulates CD4+CD25+ T reg homeostasis through dendritic cell-produced IL-2
-
Guiducci C, Valzasina B, Dislich H, Colombo MP, (2005) CD40/CD40L interaction regulates CD4+CD25+ T reg homeostasis through dendritic cell-produced IL-2. Eur J Immunol 35: 557-567.
-
(2005)
Eur J Immunol
, vol.35
, pp. 557-567
-
-
Guiducci, C.1
Valzasina, B.2
Dislich, H.3
Colombo, M.P.4
-
48
-
-
21244483422
-
TLR-dependent activation stimuli associated with Th1 responses confer NK cell stimulatory capacity to mouse dendritic cells
-
Zanoni I, Foti M, Ricciardi-Castagnoli P, Granucci F, (2005) TLR-dependent activation stimuli associated with Th1 responses confer NK cell stimulatory capacity to mouse dendritic cells. J Immunol 175: 286-292.
-
(2005)
J Immunol
, vol.175
, pp. 286-292
-
-
Zanoni, I.1
Foti, M.2
Ricciardi-Castagnoli, P.3
Granucci, F.4
-
49
-
-
20244363662
-
Syk-dependent cytokine induction by Dectin-1 reveals a novel pattern recognition pathway for C type lectins
-
Rogers NC, Slack EC, Edwards AD, Nolte MA, Schulz O, et al. (2005) Syk-dependent cytokine induction by Dectin-1 reveals a novel pattern recognition pathway for C type lectins. Immunity 22: 510-517.
-
(2005)
Immunity
, vol.22
, pp. 510-517
-
-
Rogers, N.C.1
Slack, E.C.2
Edwards, A.D.3
Nolte, M.A.4
Schulz, O.5
-
50
-
-
33847418504
-
Dectin-1 stimulation by Candida albicans yeast or zymosan triggers NFAT activation in macrophages and dendritic cells
-
Goodridge HS, Simmons RM, Underhill DM, (2007) Dectin-1 stimulation by Candida albicans yeast or zymosan triggers NFAT activation in macrophages and dendritic cells. J Immunol 178: 3107-3115.
-
(2007)
J Immunol
, vol.178
, pp. 3107-3115
-
-
Goodridge, H.S.1
Simmons, R.M.2
Underhill, D.M.3
-
51
-
-
29244482759
-
Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice
-
Tang Q, Adams JY, Tooley AJ, Bi M, Fife BT, et al. (2006) Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice. Nat Immunol 7: 83-92.
-
(2006)
Nat Immunol
, vol.7
, pp. 83-92
-
-
Tang, Q.1
Adams, J.Y.2
Tooley, A.J.3
Bi, M.4
Fife, B.T.5
-
52
-
-
0037124339
-
The basis for TCR-mediated regulation of the IL-2 receptor alpha chain gene: role of widely separated regulatory elements
-
Kim HP, Leonard WJ, (2002) The basis for TCR-mediated regulation of the IL-2 receptor alpha chain gene: role of widely separated regulatory elements. EMBO J 21: 3051-3059.
-
(2002)
EMBO J
, vol.21
, pp. 3051-3059
-
-
Kim, H.P.1
Leonard, W.J.2
-
53
-
-
33845702595
-
Upregulation of Foxp3 expression in mouse and human Treg is IL-2/STAT5 dependent: implications for the NOD STAT5B mutation in diabetes pathogenesis
-
Murawski MR, Litherland SA, Clare-Salzler MJ, Davoodi-Semiromi A, (2006) Upregulation of Foxp3 expression in mouse and human Treg is IL-2/STAT5 dependent: implications for the NOD STAT5B mutation in diabetes pathogenesis. Ann N Y Acad Sci 1079: 198-204.
-
(2006)
Ann N Y Acad Sci
, vol.1079
, pp. 198-204
-
-
Murawski, M.R.1
Litherland, S.A.2
Clare-Salzler, M.J.3
Davoodi-Semiromi, A.4
-
54
-
-
28244477625
-
Early kinetic window of target T cell susceptibility to CD25+ regulatory T cell activity
-
Sojka DK, Hughson A, Sukiennicki TL, Fowell DJ, (2005) Early kinetic window of target T cell susceptibility to CD25+ regulatory T cell activity. J Immunol 175: 7274-7280.
-
(2005)
J Immunol
, vol.175
, pp. 7274-7280
-
-
Sojka, D.K.1
Hughson, A.2
Sukiennicki, T.L.3
Fowell, D.J.4
-
55
-
-
0031821875
-
CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
-
Thornton AM, Shevach EM, (1998) CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J Exp Med 188: 287-296.
-
(1998)
J Exp Med
, vol.188
, pp. 287-296
-
-
Thornton, A.M.1
Shevach, E.M.2
-
56
-
-
0035554678
-
Inducible IL-2 production by dendritic cells revealed by global gene expression analysis
-
Granucci F, Vizzardelli C, Pavelka N, Feau S, Persico M, et al. (2001) Inducible IL-2 production by dendritic cells revealed by global gene expression analysis. Nat Immunol 2: 882-888.
-
(2001)
Nat Immunol
, vol.2
, pp. 882-888
-
-
Granucci, F.1
Vizzardelli, C.2
Pavelka, N.3
Feau, S.4
Persico, M.5
-
57
-
-
0038752591
-
Early IL-2 production by mouse dendritic cells is the result of microbial-induced priming
-
Granucci F, Feau S, Angeli V, Trottein F, Ricciardi-Castagnoli P, (2003) Early IL-2 production by mouse dendritic cells is the result of microbial-induced priming. J Immunol 170: 5075-5081.
-
(2003)
J Immunol
, vol.170
, pp. 5075-5081
-
-
Granucci, F.1
Feau, S.2
Angeli, V.3
Trottein, F.4
Ricciardi-Castagnoli, P.5
-
58
-
-
1342310077
-
Interleukin-4 selectively inhibits interleukin-2 secretion by lipopolysaccharide-activated dendritic cells
-
Sauma D, Michea P, Lennon-Duménil AM, Fierro A, Morales J, et al. (2004) Interleukin-4 selectively inhibits interleukin-2 secretion by lipopolysaccharide-activated dendritic cells. Scand J Immunol 59: 183-189.
-
(2004)
Scand J Immunol
, vol.59
, pp. 183-189
-
-
Sauma, D.1
Michea, P.2
Lennon-Duménil, A.M.3
Fierro, A.4
Morales, J.5
-
59
-
-
63849325412
-
Expansion of CD4+ CD25+ Foxp3+ T cells by bone marrow-derived dendritic cells
-
Marguti I, Yamamoto GL, da Costa TB, Rizzo LV, de Moraes LV, (2009) Expansion of CD4+ CD25+ Foxp3+ T cells by bone marrow-derived dendritic cells. Immunology 127: 50-61.
-
(2009)
Immunology
, vol.127
, pp. 50-61
-
-
Marguti, I.1
Yamamoto, G.L.2
da Costa, T.B.3
Rizzo, L.V.4
de Moraes, L.V.5
-
60
-
-
0035174336
-
A sensitive in situ ELISA for quantitative measurements of cytokines and antibodies secreted by culture lymphocytes
-
Chen Y, Peng Z, (2001) A sensitive in situ ELISA for quantitative measurements of cytokines and antibodies secreted by culture lymphocytes. J Immunoassay Immunochem 22: 353-369.
-
(2001)
J Immunoassay Immunochem
, vol.22
, pp. 353-369
-
-
Chen, Y.1
Peng, Z.2
-
61
-
-
0036469773
-
Detection of spontaneous and antigen-induced human interleukin-4 responses in vitro: comparison of ELISPOT, a novel ELISA and real-time RT-PCR
-
Ekerfelt C, Ernerudh J, Jenmalm MC, (2002) Detection of spontaneous and antigen-induced human interleukin-4 responses in vitro: comparison of ELISPOT, a novel ELISA and real-time RT-PCR. J Immunol Methods 260: 55-67.
-
(2002)
J Immunol Methods
, vol.260
, pp. 55-67
-
-
Ekerfelt, C.1
Ernerudh, J.2
Jenmalm, M.C.3
-
62
-
-
28244469262
-
Bone marrow-derived dendritic cells reverse the anergic state of CD4+CD25+ T cells without reversing their suppressive function
-
Brinster C, Shevach EM, (2005) Bone marrow-derived dendritic cells reverse the anergic state of CD4+CD25+ T cells without reversing their suppressive function. J Immunol 175: 7332-7340.
-
(2005)
J Immunol
, vol.175
, pp. 7332-7340
-
-
Brinster, C.1
Shevach, E.M.2
-
63
-
-
10844252294
-
Control of Foxp3+ CD25+CD4+ regulatory cell activation and function by dendritic cells
-
Fehérvári Z, Sakaguchi S, (2004) Control of Foxp3+ CD25+CD4+ regulatory cell activation and function by dendritic cells. Int Immunol 16: 1769-1780.
-
(2004)
Int Immunol
, vol.16
, pp. 1769-1780
-
-
Fehérvári, Z.1
Sakaguchi, S.2
-
64
-
-
0042512461
-
Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen-processing dendritic cells
-
Yamazaki S, Iyoda T, Tarbell K, Olson K, Velinzon K, et al. (2003) Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen-processing dendritic cells. J Exp Med 198: 235-247.
-
(2003)
J Exp Med
, vol.198
, pp. 235-247
-
-
Yamazaki, S.1
Iyoda, T.2
Tarbell, K.3
Olson, K.4
Velinzon, K.5
-
65
-
-
77949900562
-
Dendritic cells support homeostatic expansion of Foxp3+ regulatory T cells in Foxp3.LuciDTR mice
-
Suffner J, Hochweller K, Kühnle MC, Li X, Kroczek RA, et al. (2010) Dendritic cells support homeostatic expansion of Foxp3+ regulatory T cells in Foxp3.LuciDTR mice. J Immunol 184: 1810-1820.
-
(2010)
J Immunol
, vol.184
, pp. 1810-1820
-
-
Suffner, J.1
Hochweller, K.2
Kühnle, M.C.3
Li, X.4
Kroczek, R.A.5
-
66
-
-
69549103141
-
Feedback control of regulatory T cell homeostasis by dendritic cells in vivo
-
Darrasse-Jèze G, Deroubaix S, Mouquet H, Victora GD, Eisenreich T, et al. (2009) Feedback control of regulatory T cell homeostasis by dendritic cells in vivo. J Exp Med 206: 1853-1862.
-
(2009)
J Exp Med
, vol.206
, pp. 1853-1862
-
-
Darrasse-Jèze, G.1
Deroubaix, S.2
Mouquet, H.3
Victora, G.D.4
Eisenreich, T.5
-
67
-
-
0346366991
-
IL-15 and cognate antigen successfully expand de novo-induced human antigen-specific regulatory CD4+ T cells that require antigen-specific activation for suppression
-
Koenen HJ, Fasse E, Joosten I, (2003) IL-15 and cognate antigen successfully expand de novo-induced human antigen-specific regulatory CD4+ T cells that require antigen-specific activation for suppression. J Immunol 171: 6431-6441.
-
(2003)
J Immunol
, vol.171
, pp. 6431-6441
-
-
Koenen, H.J.1
Fasse, E.2
Joosten, I.3
-
68
-
-
2942672441
-
Cornerstone of peripheral tolerance: naturally occurring CD4+CD25+ regulatory T cells
-
Piccirillo CA, Thornton AM, (2004) Cornerstone of peripheral tolerance: naturally occurring CD4+CD25+ regulatory T cells. Trends Immunol 25: 374-380.
-
(2004)
Trends Immunol
, vol.25
, pp. 374-380
-
-
Piccirillo, C.A.1
Thornton, A.M.2
-
69
-
-
77955498156
-
Regulatory T cells: roles of T cell receptor for their development and function
-
Ohkura N, Sakaguchi S, (2010) Regulatory T cells: roles of T cell receptor for their development and function. Semin Immunopathol 32: 95-106.
-
(2010)
Semin Immunopathol
, vol.32
, pp. 95-106
-
-
Ohkura, N.1
Sakaguchi, S.2
-
70
-
-
48249103057
-
Foxp3+ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation
-
Onishi Y, Fehervari Z, Yamaguchi T, Sakaguchi S, (2008) Foxp3+ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation. Proc Natl Acad Sci U S A 105: 10113-10118.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 10113-10118
-
-
Onishi, Y.1
Fehervari, Z.2
Yamaguchi, T.3
Sakaguchi, S.4
-
71
-
-
48649095924
-
Ability of mature dendritic cells to interact with regulatory T cells is imprinted during maturation
-
Muthuswamy R, Urban J, Lee JJ, Reinhart TA, Bartlett D, et al. (2008) Ability of mature dendritic cells to interact with regulatory T cells is imprinted during maturation. Cancer Res 68: 5972-5978.
-
(2008)
Cancer Res
, vol.68
, pp. 5972-5978
-
-
Muthuswamy, R.1
Urban, J.2
Lee, J.J.3
Reinhart, T.A.4
Bartlett, D.5
-
72
-
-
0028913166
-
Endocytosis of interleukin 2 receptors in human T lymphocytes: distinct intracellular localization and fate of the receptor alpha, beta, and gamma chains
-
Hémar A, Subtil A, Lieb M, Morelon E, Hellio R, et al. (1995) Endocytosis of interleukin 2 receptors in human T lymphocytes: distinct intracellular localization and fate of the receptor alpha, beta, and gamma chains. J Cell Biol 129: 55-64.
-
(1995)
J Cell Biol
, vol.129
, pp. 55-64
-
-
Hémar, A.1
Subtil, A.2
Lieb, M.3
Morelon, E.4
Hellio, R.5
-
73
-
-
0035808301
-
The proteasome regulates receptor-mediated endocytosis of interleukin-2
-
Yu A, Malek TR, (2001) The proteasome regulates receptor-mediated endocytosis of interleukin-2. J Biol Chem 276: 381-385.
-
(2001)
J Biol Chem
, vol.276
, pp. 381-385
-
-
Yu, A.1
Malek, T.R.2
-
74
-
-
84863011757
-
Generation of immunogenic and tolerogenic clinical-grade dendritic cells
-
Kalantari T, Kamali-Sarvestani E, Ciric B, Karimi MH, Kalantari M, et al. (2011) Generation of immunogenic and tolerogenic clinical-grade dendritic cells. Immunol Res 51: 153-160.
-
(2011)
Immunol Res
, vol.51
, pp. 153-160
-
-
Kalantari, T.1
Kamali-Sarvestani, E.2
Ciric, B.3
Karimi, M.H.4
Kalantari, M.5
-
75
-
-
0025697469
-
Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo
-
Murphy KM, Heimberger AB, Loh DY, (1990) Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo. Science 250: 1720-1723.
-
(1990)
Science
, vol.250
, pp. 1720-1723
-
-
Murphy, K.M.1
Heimberger, A.B.2
Loh, D.Y.3
-
76
-
-
0029834837
-
Thymocytes can become mature T cells without passing through the CD4+ CD8+, double-positive stage
-
Liu CP, Kappler JW, Marrack P, (1996) Thymocytes can become mature T cells without passing through the CD4+ CD8+, double-positive stage. J Exp Med 184: 1619-1630.
-
(1996)
J Exp Med
, vol.184
, pp. 1619-1630
-
-
Liu, C.P.1
Kappler, J.W.2
Marrack, P.3
-
77
-
-
0037369265
-
Total lymphoid irradiation nonmyeloablative preconditioning enriches for IL-4-producing CD4+-TNK cells and skews differentiation of immunocompetent donor CD4+ cells
-
Rigby SM, Rouse T, Field EH, (2003) Total lymphoid irradiation nonmyeloablative preconditioning enriches for IL-4-producing CD4+-TNK cells and skews differentiation of immunocompetent donor CD4+ cells. Blood 101: 2024-2032.
-
(2003)
Blood
, vol.101
, pp. 2024-2032
-
-
Rigby, S.M.1
Rouse, T.2
Field, E.H.3
-
78
-
-
0035253697
-
A new regulatory region of the IL-2 locus that confers position-independent transgene expression
-
Yui MA, Hernández-Hoyos G, Rothenberg EV, (2001) A new regulatory region of the IL-2 locus that confers position-independent transgene expression. J Immunol 166: 1730-1739.
-
(2001)
J Immunol
, vol.166
, pp. 1730-1739
-
-
Yui, M.A.1
Hernández-Hoyos, G.2
Rothenberg, E.V.3
-
79
-
-
1842581852
-
Preferential activation of an IL-2 regulatory sequence transgene in TCR gamma delta and NKT cells: subset-specific differences in IL-2 regulation
-
Yui MA, Sharp LL, Havran WL, Rothenberg EV, (2004) Preferential activation of an IL-2 regulatory sequence transgene in TCR gamma delta and NKT cells: subset-specific differences in IL-2 regulation. J Immunol 172: 4691-4699.
-
(2004)
J Immunol
, vol.172
, pp. 4691-4699
-
-
Yui, M.A.1
Sharp, L.L.2
Havran, W.L.3
Rothenberg, E.V.4
|