Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
SAKAGUCHI, S. et al. 1995. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J. Immunol. 155: 1151-1164.
Thymus and autoimmunity: Production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance
ITOH, M. et al. 1999. Thymus and autoimmunity: production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance. J. Immunol. 162: 5317-5326.
CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rb-deficient mice. Implications for nonredundant function of IL-2
MALEK, T.R. et al. 2002. CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rb-deficient mice. Implications for nonredundant function of IL-2. Immunity 17: 167-178.
Essential role for STAT5 in CD25+CD4+ regulatory T cell homeostasis and the maintenance of self-tolerance
VAN PARIJS, L. et al. 2003. Essential role for STAT5 in CD25+CD4+ regulatory T cell homeostasis and the maintenance of self-tolerance. J. Immunol. 171: 3435-3441.
A mutant Stat5b with weaker DNA binding affinity defines a key defective pathway in nonobese diabetic mice
DAVOODI-SEMIROMI, A. et al. 2004. A mutant Stat5b with weaker DNA binding affinity defines a key defective pathway in nonobese diabetic mice. J. Biol. Chem. 12: 11553-11561.