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Volumn 1079, Issue , 2006, Pages 198-204

Upregulation of Foxp3 expression in mouse and human Treg is IL-2/STAT5 dependent: Implications for the NOD STAT5B mutation in diabetes pathogenesis

Author keywords

CD25; Foxp3; IL 2; Natural regulatory T cell; STAT5

Indexed keywords

INTERLEUKIN 2; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; STAT5 PROTEIN; STAT5B PROTEIN; TRANSCRIPTION FACTOR FOXP3;

EID: 33845702595     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1196/annals.1375.031     Document Type: Conference Paper
Times cited : (80)

References (11)
  • 1
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • SAKAGUCHI, S. et al. 1995. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J. Immunol. 155: 1151-1164.
    • (1995) J. Immunol. , vol.155 , pp. 1151-1164
    • Sakaguchi, S.1
  • 2
    • 0029788211 scopus 로고    scopus 로고
    • Autoimmune disease as a consequence of developmental abnormality of a T cell population
    • ASANO, M. et al. 1996. Autoimmune disease as a consequence of developmental abnormality of a T cell population. J. Exp. Med. 184: 387-396.
    • (1996) J. Exp. Med. , vol.184 , pp. 387-396
    • Asano, M.1
  • 3
    • 0033136302 scopus 로고    scopus 로고
    • Thymus and autoimmunity: Production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance
    • ITOH, M. et al. 1999. Thymus and autoimmunity: production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance. J. Immunol. 162: 5317-5326.
    • (1999) J. Immunol. , vol.162 , pp. 5317-5326
    • Itoh, M.1
  • 4
    • 0031821875 scopus 로고    scopus 로고
    • CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
    • THORNTON, A.M. & E.M. SHEVACH. 1998. CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J. Exp. Med. 188: 287-296.
    • (1998) J. Exp. Med. , vol.188 , pp. 287-296
    • Thornton, A.M.1    Shevach, E.M.2
  • 5
    • 0036669298 scopus 로고    scopus 로고
    • CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rb-deficient mice. Implications for nonredundant function of IL-2
    • MALEK, T.R. et al. 2002. CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rb-deficient mice. Implications for nonredundant function of IL-2. Immunity 17: 167-178.
    • (2002) Immunity , vol.17 , pp. 167-178
    • Malek, T.R.1
  • 6
    • 0037385330 scopus 로고    scopus 로고
    • Foxp3 programs the development and function of CD4+CD25+ T regulatory cells
    • FONTENOT, J.D. et al. 2003. Foxp3 programs the development and function of CD4+CD25+ T regulatory cells. Nat. Immunol. 4: 330-336.
    • (2003) Nat. Immunol. , vol.4 , pp. 330-336
    • Fontenot, J.D.1
  • 7
    • 0141920630 scopus 로고    scopus 로고
    • Essential role for STAT5 in CD25+CD4+ regulatory T cell homeostasis and the maintenance of self-tolerance
    • VAN PARIJS, L. et al. 2003. Essential role for STAT5 in CD25+CD4+ regulatory T cell homeostasis and the maintenance of self-tolerance. J. Immunol. 171: 3435-3441.
    • (2003) J. Immunol. , vol.171 , pp. 3435-3441
    • Van Parijs, L.1
  • 8
    • 1642483061 scopus 로고    scopus 로고
    • A mutant Stat5b with weaker DNA binding affinity defines a key defective pathway in nonobese diabetic mice
    • DAVOODI-SEMIROMI, A. et al. 2004. A mutant Stat5b with weaker DNA binding affinity defines a key defective pathway in nonobese diabetic mice. J. Biol. Chem. 12: 11553-11561.
    • (2004) J. Biol. Chem. , vol.12 , pp. 11553-11561
    • Davoodi-Semiromi, A.1
  • 9
    • 4544241811 scopus 로고    scopus 로고
    • Tolerance, not immunity, crucially depends on IL-2
    • MALEK, T.R. 2004. Tolerance, not immunity, crucially depends on IL-2. Nat. Rev. Immunol. 4: 665-674.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 665-674
    • Malek, T.R.1
  • 10
    • 27544481941 scopus 로고    scopus 로고
    • A function for interleukin 2 in Foxp3-expressing regulatory T cells
    • FONTENOT, J.D. et al. 2005. A function for interleukin 2 in Foxp3-expressing regulatory T cells. Nature Immunol. 11: 1142-1151.
    • (2005) Nature Immunol. , vol.11 , pp. 1142-1151
    • Fontenot, J.D.1
  • 11
    • 27544446622 scopus 로고    scopus 로고
    • + regulatory T cells in the absence of interleukin 2 signaling
    • + regulatory T cells in the absence of interleukin 2 signaling. Nature Immunol. 11: 1152-1159.
    • (2005) Nature Immunol. , vol.11 , pp. 1152-1159
    • D'Cruz, L.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.