Crystal structure of the IL-2 signaling complex: Paradigm for a heterotrimeric cytokine receptor

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 8, 2006, Pages 2788-2793

  Stauber, Deborah J ^a,c   Debler, Erik W ^a   Horton, Patricia A ^a,c   Smith, Kendall A ^b   Wilson, Ian A ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

Common chain; Cooperativity; IL 2 receptor; Receptor assembly; Structure activity relationship

Indexed keywords

CYTOKINE RECEPTOR; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 2 RECEPTOR BETA; INTERLEUKIN 2 RECEPTOR GAMMA;

ANIMAL CELL; ARTICLE; BINDING SITE; COMPLEX FORMATION; CORRELATION ANALYSIS; CRYSTAL STRUCTURE; HYDROGEN BOND; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN QUATERNARY STRUCTURE; RECEPTOR BINDING; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

CRYSTALLOGRAPHY; HUMANS; INTERLEUKIN-2; PROTEIN STRUCTURE, QUATERNARY; RECEPTORS, INTERLEUKIN-2; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 33644540157     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0511161103     Document Type: Article

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