Dose-response analysis of phthalate effects on gene expression in rat whole embryo culture

Toxicology and Applied Pharmacology

Volumn 264, Issue 1, 2012, Pages 32-41

  Robinson, Joshua F ^a,b   Verhoef, Aart ^a   van Beelen, Vincent A ^a   Pennings, Jeroen L A ^a   Piersma, Aldert H ^a,c  

^a NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^b MAASTRICHT UNIVERSITY   (Netherlands)

^c UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Cholesterol; Embryo; Gene expression; Neurulation; Phthalate; Potency; Steroid; Toxicogenomics; Whole embryo culture

Indexed keywords

CHOLESTEROL; LIPID; MOLECULAR MARKER; MONOMETHYL PHTHALATE; PHTHALIC ACID 2 ETHYLHEXYL MONOESTER; PHTHALIC ACID DERIVATIVE; STEROID; TRANSCRIPTOME; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CHOLESTEROL METABOLISM; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEVELOPMENTAL TOXICITY; DOSE RESPONSE; DRUG POTENCY; EMBRYO; EMBRYO CULTURE; EMBRYO DEVELOPMENT; FEMALE; GENE CONTROL; GENE EXPRESSION; GENOTOXICITY; IN VIVO STUDY; LIPID METABOLISM; MALE; METABOLIC REGULATION; MORPHOGENESIS; NONHUMAN; RAT; STEROID METABOLISM;

ANIMALS; APOPTOSIS; CHOLESTEROL; DIETHYLHEXYL PHTHALATE; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYO CULTURE TECHNIQUES; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; LIPID METABOLISM; MALE; PHTHALIC ACIDS; PREGNANCY; RATS; RATS, WISTAR; STEROIDS; TOXICOGENETICS; TRANSCRIPTOME;

RATTUS;

EID: 84865995530     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2012.07.015     Document Type: Article

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