Dose-response assessment of fetal testosterone production and gene expression levels in rat testes following In Utero exposure to diethylhexyl phthalate, diisobutyl phthalate, diisoheptyl phthalate, and diisononyl phthalate

Toxicological Sciences

Volumn 123, Issue 1, 2011, Pages 206-216

  Hannas, Bethany R ^a   Lambright, Christy S ^a   Furr, Johnathan ^a   Howdeshell, Kembra L ^a,b   Wilson, Vickie S ^a   Gray Jr , Leon E ^a  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Developmental toxicity; Endocrine disruptors; Endocrine toxicology; Prenatal; Reproductive and developmental toxicology; Testis

Indexed keywords

DIISOBUTYLPHTHALATE; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER; PHTHALIC ACID BIS(5 METHYLHEXYL) ESTER; PHTHALIC ACID DIISONONYL ESTER; PHTHALIC ACID ESTER; TESTOSTERONE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; COMPARATIVE STUDY; DOSE RESPONSE; EXPOSURE; FETUS; GENE EXPRESSION; MALE; NONHUMAN; POLYMERASE CHAIN REACTION; RAT; TESTIS; TESTIS FUNCTION;

ANIMALS; CYTOCHROME P-450 CYP1A1; DIBUTYL PHTHALATE; DIETHYLHEXYL PHTHALATE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FETUS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; INSULIN; MALE; MATERNAL EXPOSURE; MEMBRANE TRANSPORT PROTEINS; PHOSPHOPROTEINS; PHTHALIC ACIDS; PLASTICIZERS; PREGNANCY; PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; SPECIES SPECIFICITY; TESTIS; TESTOSTERONE;

RATTUS;

EID: 80052439412     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfr146     Document Type: Article

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