-
1
-
-
65249110433
-
Defining developmental potency and cell lineage trajectories by expression profiling of differentiating mouse embryonic stem cells
-
Aiba K., Nedorezov T., Piao Y., Nishiyama A., Matoba R., Sharova L.V., Sharov A.A., Yamanaka S., Niwa H., Ko M.S. Defining developmental potency and cell lineage trajectories by expression profiling of differentiating mouse embryonic stem cells. DNA Res. 2009, 16:73-80.
-
(2009)
DNA Res.
, vol.16
, pp. 73-80
-
-
Aiba, K.1
Nedorezov, T.2
Piao, Y.3
Nishiyama, A.4
Matoba, R.5
Sharova, L.V.6
Sharov, A.A.7
Yamanaka, S.8
Niwa, H.9
Ko, M.S.10
-
2
-
-
51849115581
-
Genomic signatures and dose-dependent transitions in nasal epithelial responses to inhaled formaldehyde in the rat
-
Andersen M.E., Clewell H.J., Bermudez E., Willson G.A., Thomas R.S. Genomic signatures and dose-dependent transitions in nasal epithelial responses to inhaled formaldehyde in the rat. Toxicol. Sci. 2008, 105:368-383.
-
(2008)
Toxicol. Sci.
, vol.105
, pp. 368-383
-
-
Andersen, M.E.1
Clewell, H.J.2
Bermudez, E.3
Willson, G.A.4
Thomas, R.S.5
-
3
-
-
79851510896
-
Anon INVITTOX protocol 113
-
Anon INVITTOX protocol 113 http://ecvam-dbalm.jrc.ec.europa.eu/.
-
-
-
-
4
-
-
77049090813
-
Predicting the hepatocarcinogenic potential of alkenylbenzene flavoring agents using toxicogenomics and machine learning
-
Auerbach S.S., Shah R.R., Mav D., Smith C.S., Walker N.J., Vallant M.K., Boorman G.A., Irwin R.D. Predicting the hepatocarcinogenic potential of alkenylbenzene flavoring agents using toxicogenomics and machine learning. Toxicol. Appl. Pharmacol. 2010, 243:300-314.
-
(2010)
Toxicol. Appl. Pharmacol.
, vol.243
, pp. 300-314
-
-
Auerbach, S.S.1
Shah, R.R.2
Mav, D.3
Smith, C.S.4
Walker, N.J.5
Vallant, M.K.6
Boorman, G.A.7
Irwin, R.D.8
-
5
-
-
34447093802
-
In vitro immunotoxicity of bis(tri-n-butyltin)oxide (TBTO) studied by toxicogenomics
-
Baken K.A., Arkusz J., Pennings J.L., Vandebriel R.J., van Loveren H. In vitro immunotoxicity of bis(tri-n-butyltin)oxide (TBTO) studied by toxicogenomics. Toxicology 2007, 237:35-48.
-
(2007)
Toxicology
, vol.237
, pp. 35-48
-
-
Baken, K.A.1
Arkusz, J.2
Pennings, J.L.3
Vandebriel, R.J.4
van Loveren, H.5
-
6
-
-
0032856081
-
The relative semi-quantification of mRNA expression as a useful toxicological endpoint for the identification of embryotoxic/teratogenic substances
-
Bigot K., de Lange J., Archer G., Clothier R., Bremer S. The relative semi-quantification of mRNA expression as a useful toxicological endpoint for the identification of embryotoxic/teratogenic substances. Toxicol. in Vitro 1999, 13:619-623.
-
(1999)
Toxicol. in Vitro
, vol.13
, pp. 619-623
-
-
Bigot, K.1
de Lange, J.2
Archer, G.3
Clothier, R.4
Bremer, S.5
-
7
-
-
0037316303
-
A comparison of normalization methods for high density oligonucleotide array data based on variance and bias
-
Bolstad B.M., Irizarry R.A., Astrand M., Speed T.P. A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. Bioinformatics 2003, 19:185-193.
-
(2003)
Bioinformatics
, vol.19
, pp. 185-193
-
-
Bolstad, B.M.1
Irizarry, R.A.2
Astrand, M.3
Speed, T.P.4
-
8
-
-
0034518116
-
Toxicogenomics-based discrimination of toxic mechanism in HepG2 human hepatoma cells
-
Burczynski M.E., McMillian M., Ciervo J., Li L., Parker J.B., Dunn R.T., Hicken S., Farr S., Johnson M.D. Toxicogenomics-based discrimination of toxic mechanism in HepG2 human hepatoma cells. Toxicol. Sci. 2000, 58:399-415.
-
(2000)
Toxicol. Sci.
, vol.58
, pp. 399-415
-
-
Burczynski, M.E.1
McMillian, M.2
Ciervo, J.3
Li, L.4
Parker, J.B.5
Dunn, R.T.6
Hicken, S.7
Farr, S.8
Johnson, M.D.9
-
9
-
-
29144535372
-
Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data
-
Dai M., Wang P., Boyd A.D., Kostov G., Athey B., Jones E.G., Bunney W.E., Myers R.M., Speed T.P., Akil H., Watson S.J., Meng F. Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data. Nucleic Acids Res. 2005, 33:e175.
-
(2005)
Nucleic Acids Res.
, vol.33
-
-
Dai, M.1
Wang, P.2
Boyd, A.D.3
Kostov, G.4
Athey, B.5
Jones, E.G.6
Bunney, W.E.7
Myers, R.M.8
Speed, T.P.9
Akil, H.10
Watson, S.J.11
Meng, F.12
-
10
-
-
77952286275
-
Integrating gene expression and GO classification for PCA by preclustering
-
De Haan J.R., Piek E., van Schaik R.C., de Vlieg J., Bauerschmidt S., Buydens L.M., Wehrens R. Integrating gene expression and GO classification for PCA by preclustering. BMC Bioinform. 2010, 11:158.
-
(2010)
BMC Bioinform.
, vol.11
, pp. 158
-
-
De Haan, J.R.1
Piek, E.2
van Schaik, R.C.3
de Vlieg, J.4
Bauerschmidt, S.5
Buydens, L.M.6
Wehrens, R.7
-
11
-
-
51749104176
-
Optimisation of the cell cultivation methods in the embryonic stem cell test results in an increased differentiation potential of the cells into strong beating myocard cells
-
De Smedt A., Steemans M., De Boeck M., Peters A.K., van der Leede B.J., Van Goethem F., Lampo A., Vanparys P. Optimisation of the cell cultivation methods in the embryonic stem cell test results in an increased differentiation potential of the cells into strong beating myocard cells. Toxicol. In Vitro 2008, 22:1789-1796.
-
(2008)
Toxicol. In Vitro
, vol.22
, pp. 1789-1796
-
-
De Smedt, A.1
Steemans, M.2
De Boeck, M.3
Peters, A.K.4
van der Leede, B.J.5
Van Goethem, F.6
Lampo, A.7
Vanparys, P.8
-
12
-
-
0037263812
-
MAPPFinder: using Gene Ontology and GenMAPP to create a global gene-expression profile from microarray data
-
Doniger S.W., Salomonis N., Dahlquist K.D., Vranizan K., Lawlor S.C., Conklin B.R. MAPPFinder: using Gene Ontology and GenMAPP to create a global gene-expression profile from microarray data. Genome Biol. 2003, 4:R7.
-
(2003)
Genome Biol.
, vol.4
-
-
Doniger, S.W.1
Salomonis, N.2
Dahlquist, K.D.3
Vranizan, K.4
Lawlor, S.C.5
Conklin, B.R.6
-
13
-
-
37149025669
-
Prediction of a carcinogenic potential of rat hepatocarcinogens using toxicogenomics analysis of short-term in vivo studies
-
Ellinger-Ziegelbauer H., Gmuender H., Bandenburg A., Ahr H.J. Prediction of a carcinogenic potential of rat hepatocarcinogens using toxicogenomics analysis of short-term in vivo studies. Mutat. Res. 2008, 637:23-39.
-
(2008)
Mutat. Res.
, vol.637
, pp. 23-39
-
-
Ellinger-Ziegelbauer, H.1
Gmuender, H.2
Bandenburg, A.3
Ahr, H.J.4
-
14
-
-
2642576049
-
Toxicogenomics of subchronic hexachlorobenzene exposure in Brown Norway rats
-
Ezendam J., Staedtler F., Pennings J., Vandebriel R.J., Pieters R., Harleman J.H., Vos J.G. Toxicogenomics of subchronic hexachlorobenzene exposure in Brown Norway rats. Environ. Health Perspect. 2004, 112:782-791.
-
(2004)
Environ. Health Perspect.
, vol.112
, pp. 782-791
-
-
Ezendam, J.1
Staedtler, F.2
Pennings, J.3
Vandebriel, R.J.4
Pieters, R.5
Harleman, J.H.6
Vos, J.G.7
-
15
-
-
77954911545
-
Transcriptome analysis of early organogenesis in human embryos
-
Fang H., Yang Y., Li C., Fu S., Yang Z., Jin G., Wang K., Zhang J., Jin Y. Transcriptome analysis of early organogenesis in human embryos. Dev. Cell 2010, 19:174-184.
-
(2010)
Dev. Cell
, vol.19
, pp. 174-184
-
-
Fang, H.1
Yang, Y.2
Li, C.3
Fu, S.4
Yang, Z.5
Jin, G.6
Wang, K.7
Zhang, J.8
Jin, Y.9
-
16
-
-
33847206773
-
Developmental toxic effects of antifungal flusilazole administered by gavage to mice
-
Farag A.T., Ibrahim H.H. Developmental toxic effects of antifungal flusilazole administered by gavage to mice. Birth Defects Res. B Dev. Reprod. Toxicol. 2007, 80:12-17.
-
(2007)
Birth Defects Res. B Dev. Reprod. Toxicol.
, vol.80
, pp. 12-17
-
-
Farag, A.T.1
Ibrahim, H.H.2
-
17
-
-
34547881497
-
A gene expression biomarker provides early prediction and mechanistic assessment of hepatic tumor induction by nongenotoxic chemicals
-
Fielden M.R., Brennan R., Gollub J. A gene expression biomarker provides early prediction and mechanistic assessment of hepatic tumor induction by nongenotoxic chemicals. Toxicol. Sci. 2007, 99:90-100.
-
(2007)
Toxicol. Sci.
, vol.99
, pp. 90-100
-
-
Fielden, M.R.1
Brennan, R.2
Gollub, J.3
-
18
-
-
0021732321
-
An in vitro assay for teratogens with cultures of rat embryo midbrain and limb bud cells
-
Flint O.P., Orton T.C. An in vitro assay for teratogens with cultures of rat embryo midbrain and limb bud cells. Toxicol. Appl. Pharmacol. 1984, 76:383-395.
-
(1984)
Toxicol. Appl. Pharmacol.
, vol.76
, pp. 383-395
-
-
Flint, O.P.1
Orton, T.C.2
-
19
-
-
8744223170
-
Validation of the embryonic stem cell test in the international ECVAM validation study on three in vitro embryotoxicity tests
-
Genschow E., Spielmann H., Scholz G., Pohl I., Seiler A., Clemann N., Bremer S., Becker K. Validation of the embryonic stem cell test in the international ECVAM validation study on three in vitro embryotoxicity tests. Altern. Lab. Anim. 2004, 32:209-244.
-
(2004)
Altern. Lab. Anim.
, vol.32
, pp. 209-244
-
-
Genschow, E.1
Spielmann, H.2
Scholz, G.3
Pohl, I.4
Seiler, A.5
Clemann, N.6
Bremer, S.7
Becker, K.8
-
20
-
-
0032882718
-
Antifungal agents: mode of action, mechanisms of resistance, and correlation of these mechanisms with bacterial resistance
-
Ghannoum M.A., Rice L.B. Antifungal agents: mode of action, mechanisms of resistance, and correlation of these mechanisms with bacterial resistance. Clin. Microbiol. Rev. 1999, 12:501-517.
-
(1999)
Clin. Microbiol. Rev.
, vol.12
, pp. 501-517
-
-
Ghannoum, M.A.1
Rice, L.B.2
-
21
-
-
67650760524
-
Mode of action for reproductive and hepatic toxicity inferred from a genomic study of triazole antifungals
-
Goetz A.K., Dix D.J. Mode of action for reproductive and hepatic toxicity inferred from a genomic study of triazole antifungals. Toxicol. Sci. 2009, 110:449-462.
-
(2009)
Toxicol. Sci.
, vol.110
, pp. 449-462
-
-
Goetz, A.K.1
Dix, D.J.2
-
22
-
-
77954086163
-
Unexpected common mechanistic pathways for embryotoxicity of warfarin and lovastatin
-
Groebe K., Hayess K., Klemm-Manns M., Schwall G., Wozny W., Steemans M., Peters A.K., Sastri C., Jaeckel P., Stegmann W., Zengerling H., Schopf R., Poznanovic S., Stummann T.C., Seiler A., Spielmann H., Schrattenholz A. Unexpected common mechanistic pathways for embryotoxicity of warfarin and lovastatin. Reprod. Toxicol. 2010, 30:121-130.
-
(2010)
Reprod. Toxicol.
, vol.30
, pp. 121-130
-
-
Groebe, K.1
Hayess, K.2
Klemm-Manns, M.3
Schwall, G.4
Wozny, W.5
Steemans, M.6
Peters, A.K.7
Sastri, C.8
Jaeckel, P.9
Stegmann, W.10
Zengerling, H.11
Schopf, R.12
Poznanovic, S.13
Stummann, T.C.14
Seiler, A.15
Spielmann, H.16
Schrattenholz, A.17
-
23
-
-
3242742968
-
Gene expression profiling of rat livers reveals indicators of potential adverse effects
-
Heinloth A.N., Irwin R.D., Boorman G.A., Nettesheim P., Fannin R.D., Sieber S.O., Snell M.L., Tucker C.J., Li L., Travlos G.S., Vansant G., Blackshear P.E., Tennant R.W., Cunningham M.L., Paules R.S. Gene expression profiling of rat livers reveals indicators of potential adverse effects. Toxicol. Sci. 2004, 80:193-202.
-
(2004)
Toxicol. Sci.
, vol.80
, pp. 193-202
-
-
Heinloth, A.N.1
Irwin, R.D.2
Boorman, G.A.3
Nettesheim, P.4
Fannin, R.D.5
Sieber, S.O.6
Snell, M.L.7
Tucker, C.J.8
Li, L.9
Travlos, G.S.10
Vansant, G.11
Blackshear, P.E.12
Tennant, R.W.13
Cunningham, M.L.14
Paules, R.S.15
-
24
-
-
34547589578
-
DAVID Bioinformatics Resources: expanded annotation database and novel algorithms to better extract biology from large gene lists
-
Huang da W., Sherman B.T., Tan Q., Kir J., Liu D., Bryant D., Guo Y., Stephens R., Baseler M.W., Lane H.C., Lempicki R.A. DAVID Bioinformatics Resources: expanded annotation database and novel algorithms to better extract biology from large gene lists. Nucleic Acids Res. 2007, 35:W169-W175.
-
(2007)
Nucleic Acids Res.
, vol.35
-
-
Huang da, W.1
Sherman, B.T.2
Tan, Q.3
Kir, J.4
Liu, D.5
Bryant, D.6
Guo, Y.7
Stephens, R.8
Baseler, M.W.9
Lane, H.C.10
Lempicki, R.A.11
-
25
-
-
0142121516
-
Exploration, normalization, and summaries of high density oligonucleotide array probe level data
-
Irizarry R.A., Hobbs B., Collin F., Beazer-Barclay Y.D., Antonellis K.J., Scherf U., Speed T.P. Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 2003, 4:249-264.
-
(2003)
Biostatistics
, vol.4
, pp. 249-264
-
-
Irizarry, R.A.1
Hobbs, B.2
Collin, F.3
Beazer-Barclay, Y.D.4
Antonellis, K.J.5
Scherf, U.6
Speed, T.P.7
-
26
-
-
70349980157
-
Finding transcriptomics biomarkers for in vivo identification of (non-)genotoxic carcinogens using wild-type and Xpa/p53 mutant mouse models
-
Jonker M.J., Bruning O., van Iterson M., Schaap M.M., van der Hoeven T.V., Vrieling H., Beems R.B., de Vries A., van Steeg H., Breit T.M., Luijten M. Finding transcriptomics biomarkers for in vivo identification of (non-)genotoxic carcinogens using wild-type and Xpa/p53 mutant mouse models. Carcinogenesis 2009, 30:1805-1812.
-
(2009)
Carcinogenesis
, vol.30
, pp. 1805-1812
-
-
Jonker, M.J.1
Bruning, O.2
van Iterson, M.3
Schaap, M.M.4
van der Hoeven, T.V.5
Vrieling, H.6
Beems, R.B.7
de Vries, A.8
van Steeg, H.9
Breit, T.M.10
Luijten, M.11
-
27
-
-
1942453842
-
Acute molecular markers of rodent hepatic carcinogenesis identified by transcription profiling
-
Kramer J.A., Curtiss S.W., Kolaja K.L., Alden C.L., Blomme E.A., Curtiss W.C., Davila J.C., Jackson C.J., Bunch R.T. Acute molecular markers of rodent hepatic carcinogenesis identified by transcription profiling. Chem. Res. Toxicol. 2004, 17:463-470.
-
(2004)
Chem. Res. Toxicol.
, vol.17
, pp. 463-470
-
-
Kramer, J.A.1
Curtiss, S.W.2
Kolaja, K.L.3
Alden, C.L.4
Blomme, E.A.5
Curtiss, W.C.6
Davila, J.C.7
Jackson, C.J.8
Bunch, R.T.9
-
28
-
-
77956442714
-
Early transcriptional responses in mouse embryos as a basis for selection of molecular markers predictive of valproic acid teratogenicity
-
Kultima K., Jergil M., Salter H., Gustafson A.L., Dencker L., Stigson M. Early transcriptional responses in mouse embryos as a basis for selection of molecular markers predictive of valproic acid teratogenicity. Reprod. Toxicol. 2010, 30:457-468.
-
(2010)
Reprod. Toxicol.
, vol.30
, pp. 457-468
-
-
Kultima, K.1
Jergil, M.2
Salter, H.3
Gustafson, A.L.4
Dencker, L.5
Stigson, M.6
-
29
-
-
39949083946
-
Cripto-independent Nodal signaling promotes positioning of the A-P axis in the early mouse embryo
-
Liguori G.L., Borges A.C., D'Andrea D., Liguoro A., Goncalves L., Salgueiro A.M., Persico M.G., Belo J.A. Cripto-independent Nodal signaling promotes positioning of the A-P axis in the early mouse embryo. Dev. Biol. 2008, 315:280-289.
-
(2008)
Dev. Biol.
, vol.315
, pp. 280-289
-
-
Liguori, G.L.1
Borges, A.C.2
D'Andrea, D.3
Liguoro, A.4
Goncalves, L.5
Salgueiro, A.M.6
Persico, M.G.7
Belo, J.A.8
-
30
-
-
69849088915
-
A review of the implementation of the embryonic stem cell test (EST). The report and recommendations of an ECVAM/ReProTect Workshop
-
Marx-Stoelting P., Adriaens E., Ahr H.J., Bremer S., Garthoff B., Gelbke H.P., Piersma A., Pellizzer C., Reuter U., Rogiers V., Schenk B., Schwengberg S., Seiler A., Spielmann H., Steemans M., Stedman D.B., Vanparys P., Vericat J.A., Verwei M., van der Water F., Weimer M., Schwarz M. A review of the implementation of the embryonic stem cell test (EST). The report and recommendations of an ECVAM/ReProTect Workshop. Altern. Lab. Anim. 2009, 37:313-328.
-
(2009)
Altern. Lab. Anim.
, vol.37
, pp. 313-328
-
-
Marx-Stoelting, P.1
Adriaens, E.2
Ahr, H.J.3
Bremer, S.4
Garthoff, B.5
Gelbke, H.P.6
Piersma, A.7
Pellizzer, C.8
Reuter, U.9
Rogiers, V.10
Schenk, B.11
Schwengberg, S.12
Seiler, A.13
Spielmann, H.14
Steemans, M.15
Stedman, D.B.16
Vanparys, P.17
Vericat, J.A.18
Verwei, M.19
van der Water, F.20
Weimer, M.21
Schwarz, M.22
more..
-
31
-
-
26444549446
-
Gene expression changes induced in the testis by transplacental exposure to high and low doses of 17{alpha}-ethynyl estradiol, genistein, or bisphenol A
-
Naciff J.M., Hess K.A., Overmann G.J., Torontali S.M., Carr G.J., Tiesman J.P., Foertsch L.M., Richardson B.D., Martinez J.E., Daston G.P. Gene expression changes induced in the testis by transplacental exposure to high and low doses of 17{alpha}-ethynyl estradiol, genistein, or bisphenol A. Toxicol. Sci. 2005, 86:396-416.
-
(2005)
Toxicol. Sci.
, vol.86
, pp. 396-416
-
-
Naciff, J.M.1
Hess, K.A.2
Overmann, G.J.3
Torontali, S.M.4
Carr, G.J.5
Tiesman, J.P.6
Foertsch, L.M.7
Richardson, B.D.8
Martinez, J.E.9
Daston, G.P.10
-
32
-
-
77950021154
-
The genomic response of Ishikawa cells to bisphenol A exposure is dose- and time-dependent
-
Naciff J.M., Khambatta Z.S., Reichling T.D., Carr G.J., Tiesman J.P., Singleton D.W., Khan S.A., Daston G.P. The genomic response of Ishikawa cells to bisphenol A exposure is dose- and time-dependent. Toxicology 2010, 270:137-149.
-
(2010)
Toxicology
, vol.270
, pp. 137-149
-
-
Naciff, J.M.1
Khambatta, Z.S.2
Reichling, T.D.3
Carr, G.J.4
Tiesman, J.P.5
Singleton, D.W.6
Khan, S.A.7
Daston, G.P.8
-
33
-
-
33845462135
-
Predictive toxicogenomics approaches reveal underlying molecular mechanisms of nongenotoxic carcinogenicity
-
Nie A.Y., McMillian M., Parker J.B., Leone A., Bryant S., Yieh L., Bittner A., Nelson J., Carmen A., Wan J., Lord P.G. Predictive toxicogenomics approaches reveal underlying molecular mechanisms of nongenotoxic carcinogenicity. Mol. Carcinog. 2006, 45:914-933.
-
(2006)
Mol. Carcinog.
, vol.45
, pp. 914-933
-
-
Nie, A.Y.1
McMillian, M.2
Parker, J.B.3
Leone, A.4
Bryant, S.5
Yieh, L.6
Bittner, A.7
Nelson, J.8
Carmen, A.9
Wan, J.10
Lord, P.G.11
-
34
-
-
41949130690
-
Identification of presomitic mesoderm (PSM)-specific Mesp1 enhancer and generation of a PSM-specific Mesp1/Mesp2-null mouse using BAC-based rescue technology
-
Oginuma M., Hirata T., Saga Y. Identification of presomitic mesoderm (PSM)-specific Mesp1 enhancer and generation of a PSM-specific Mesp1/Mesp2-null mouse using BAC-based rescue technology. Mech. Dev. 2008, 125:432-440.
-
(2008)
Mech. Dev.
, vol.125
, pp. 432-440
-
-
Oginuma, M.1
Hirata, T.2
Saga, Y.3
-
35
-
-
8744293605
-
Validation of the postimplantation rat whole-embryo culture test in the international ECVAM validation study on three in vitro embryotoxicity tests
-
Piersma A.H., Genschow E., Verhoef A., Spanjersberg M.Q., Brown N.A., Brady M., Burns A., Clemann N., Seiler A., Spielmann H. Validation of the postimplantation rat whole-embryo culture test in the international ECVAM validation study on three in vitro embryotoxicity tests. Altern. Lab. Anim. 2004, 32:275-307.
-
(2004)
Altern. Lab. Anim.
, vol.32
, pp. 275-307
-
-
Piersma, A.H.1
Genschow, E.2
Verhoef, A.3
Spanjersberg, M.Q.4
Brown, N.A.5
Brady, M.6
Burns, A.7
Clemann, N.8
Seiler, A.9
Spielmann, H.10
-
36
-
-
2542628846
-
Otx2 regulates the extent, identity and fate of neuronal progenitor domains in the ventral midbrain
-
Puelles E., Annino A., Tuorto F., Usiello A., Acampora D., Czerny T., Brodski C., Ang S.L., Wurst W., Simeone A. Otx2 regulates the extent, identity and fate of neuronal progenitor domains in the ventral midbrain. Development 2004, 131:2037-2048.
-
(2004)
Development
, vol.131
, pp. 2037-2048
-
-
Puelles, E.1
Annino, A.2
Tuorto, F.3
Usiello, A.4
Acampora, D.5
Czerny, T.6
Brodski, C.7
Ang, S.L.8
Wurst, W.9
Simeone, A.10
-
37
-
-
77953646021
-
A systems-based approach to investigate dose- and time-dependent methylmercury-induced gene expression response in C57BL/6 mouse embryos undergoing neurulation
-
Robinson J.F., Guerrette Z., Yu X., Hong S., Faustman E.M. A systems-based approach to investigate dose- and time-dependent methylmercury-induced gene expression response in C57BL/6 mouse embryos undergoing neurulation. Birth Defects Res. B Dev. Reprod. Toxicol. 2010, 89:188-200.
-
(2010)
Birth Defects Res. B Dev. Reprod. Toxicol.
, vol.89
, pp. 188-200
-
-
Robinson, J.F.1
Guerrette, Z.2
Yu, X.3
Hong, S.4
Faustman, E.M.5
-
38
-
-
41349116565
-
A framework to identify physiological responses in microarray-based gene expression studies: selection and interpretation of biologically relevant genes
-
Rodenburg W., Heidema A.G., Boer J.M., Bovee-Oudenhoven I.M., Feskens E.J., Mariman E.C., Keijer J. A framework to identify physiological responses in microarray-based gene expression studies: selection and interpretation of biologically relevant genes. Physiol. Genomics 2008, 33:78-90.
-
(2008)
Physiol. Genomics
, vol.33
, pp. 78-90
-
-
Rodenburg, W.1
Heidema, A.G.2
Boer, J.M.3
Bovee-Oudenhoven, I.M.4
Feskens, E.J.5
Mariman, E.C.6
Keijer, J.7
-
39
-
-
33847724787
-
Zebrafish assays for drug toxicity screening
-
Rubinstein A.L. Zebrafish assays for drug toxicity screening. Expert Opin. Drug Metab. Toxicol. 2006, 2:231-240.
-
(2006)
Expert Opin. Drug Metab. Toxicol.
, vol.2
, pp. 231-240
-
-
Rubinstein, A.L.1
-
40
-
-
0028806048
-
Quantitative monitoring of gene expression patterns with a complementary DNA microarray
-
Schena M., Shalon D., Davis R.W., Brown P.O. Quantitative monitoring of gene expression patterns with a complementary DNA microarray. Science 1995, 270:467-470.
-
(1995)
Science
, vol.270
, pp. 467-470
-
-
Schena, M.1
Shalon, D.2
Davis, R.W.3
Brown, P.O.4
-
41
-
-
1542618024
-
Improvement of an in vitro stem cell assay for developmental toxicity: the use of molecular endpoints in the embryonic stem cell test
-
Seiler A., Visan A., Buesen R., Genschow E., Spielmann H. Improvement of an in vitro stem cell assay for developmental toxicity: the use of molecular endpoints in the embryonic stem cell test. Reprod. Toxicol. 2004, 18:231-240.
-
(2004)
Reprod. Toxicol.
, vol.18
, pp. 231-240
-
-
Seiler, A.1
Visan, A.2
Buesen, R.3
Genschow, E.4
Spielmann, H.5
-
42
-
-
15944425036
-
Computational systems analysis of developmental toxicity: design, development and implementation of a Birth Defects Systems Manager (BDSM)
-
Singh A.V., Knudsen K.B., Knudsen T.B. Computational systems analysis of developmental toxicity: design, development and implementation of a Birth Defects Systems Manager (BDSM). Reprod. Toxicol. 2005, 19:421-439.
-
(2005)
Reprod. Toxicol.
, vol.19
, pp. 421-439
-
-
Singh, A.V.1
Knudsen, K.B.2
Knudsen, T.B.3
-
43
-
-
0036206395
-
Dose-response modeling of continuous endpoints
-
Slob W. Dose-response modeling of continuous endpoints. Toxicol. Sci. 2002, 66:298-312.
-
(2002)
Toxicol. Sci.
, vol.66
, pp. 298-312
-
-
Slob, W.1
-
44
-
-
0024397254
-
Comparative effects of the azole-based fungicide flusilazole on yeast and mammalian lanosterol 14 alpha-methyl demethylase
-
Trzaskos J.M., Henry M.J. Comparative effects of the azole-based fungicide flusilazole on yeast and mammalian lanosterol 14 alpha-methyl demethylase. Antimicrob. Agents Chemother. 1989, 33:1228-1231.
-
(1989)
Antimicrob. Agents Chemother.
, vol.33
, pp. 1228-1231
-
-
Trzaskos, J.M.1
Henry, M.J.2
-
45
-
-
33746914451
-
Gene expression profiling in liver and testis of rats to characterize the toxicity of triazole fungicides
-
Tully D.B., Bao W., Goetz A.K., Blystone C.R., Ren H., Schmid J.E., Strader L.F., Wood C.R., Best D.S., Narotsky M.G., Wolf D.C., Rockett J.C., Dix D.J. Gene expression profiling in liver and testis of rats to characterize the toxicity of triazole fungicides. Toxicol. Appl. Pharmacol. 2006, 215:260-273.
-
(2006)
Toxicol. Appl. Pharmacol.
, vol.215
, pp. 260-273
-
-
Tully, D.B.1
Bao, W.2
Goetz, A.K.3
Blystone, C.R.4
Ren, H.5
Schmid, J.E.6
Strader, L.F.7
Wood, C.R.8
Best, D.S.9
Narotsky, M.G.10
Wolf, D.C.11
Rockett, J.C.12
Dix, D.J.13
-
46
-
-
47849128187
-
A toxicogenomics approach for early assessment of potential non-genotoxic hepatocarcinogenicity of chemicals in rats
-
Uehara T., Hirode M., Ono A., Kiyosawa N., Omura K., Shimizu T., Mizukawa Y., Miyagishima T., Nagao T., Urushidani T. A toxicogenomics approach for early assessment of potential non-genotoxic hepatocarcinogenicity of chemicals in rats. Toxicology 2008, 250:15-26.
-
(2008)
Toxicology
, vol.250
, pp. 15-26
-
-
Uehara, T.1
Hirode, M.2
Ono, A.3
Kiyosawa, N.4
Omura, K.5
Shimizu, T.6
Mizukawa, Y.7
Miyagishima, T.8
Nagao, T.9
Urushidani, T.10
-
47
-
-
78650538006
-
Evaluation of developmental toxicant identification using gene expression profiling in embryonic stem cell differentiation cultures
-
van Dartel D.A.M., Pennings J.L.A., de la Fonteyne L.J.J., Brauers K.J.J., Claessen S.M.H., van Delft J.H., Kleinjans J.C.C., Piersma A.H. Evaluation of developmental toxicant identification using gene expression profiling in embryonic stem cell differentiation cultures. Toxicol. Sci. 2011, 119:126-134.
-
(2011)
Toxicol. Sci.
, vol.119
, pp. 126-134
-
-
van Dartel, D.A.M.1
Pennings, J.L.A.2
de la Fonteyne, L.J.J.3
Brauers, K.J.J.4
Claessen, S.M.H.5
van Delft, J.H.6
Kleinjans, J.C.C.7
Piersma, A.H.8
-
48
-
-
77954364273
-
Monitoring developmental toxicity in the embryonic stem cell test using differential gene expression of differentiation-related genes
-
van Dartel D.A.M., Pennings J.L.A., de la Fonteyne L.J.J., van Herwijnen M., van Delft J.H., van Schooten F.J., Piersma A.H. Monitoring developmental toxicity in the embryonic stem cell test using differential gene expression of differentiation-related genes. Toxicol. Sci. 2010, 116:130-139.
-
(2010)
Toxicol. Sci.
, vol.116
, pp. 130-139
-
-
van Dartel, D.A.M.1
Pennings, J.L.A.2
de la Fonteyne, L.J.J.3
van Herwijnen, M.4
van Delft, J.H.5
van Schooten, F.J.6
Piersma, A.H.7
-
49
-
-
62549124073
-
Early gene expression changes during embryonic stem cell differentiation into cardiomyocytes and their modulation by monobutyl phthalate
-
van Dartel D.A.M., Pennings J.L.A., Hendriksen P.J., van Schooten F.J., Piersma A.H. Early gene expression changes during embryonic stem cell differentiation into cardiomyocytes and their modulation by monobutyl phthalate. Reprod. Toxicol. 2009, 27:93-102.
-
(2009)
Reprod. Toxicol.
, vol.27
, pp. 93-102
-
-
van Dartel, D.A.M.1
Pennings, J.L.A.2
Hendriksen, P.J.3
van Schooten, F.J.4
Piersma, A.H.5
-
50
-
-
77049106803
-
Transcriptomics-based identification of developmental toxicants through their interference with cardiomyocyte differentiation of embryonic stem cells
-
van Dartel D.A.M., Pennings J.L.A., van Schooten F.J., Piersma A.H. Transcriptomics-based identification of developmental toxicants through their interference with cardiomyocyte differentiation of embryonic stem cells. Toxicol. Appl. Pharmacol. 2010, 243:420-428.
-
(2010)
Toxicol. Appl. Pharmacol.
, vol.243
, pp. 420-428
-
-
van Dartel, D.A.M.1
Pennings, J.L.A.2
van Schooten, F.J.3
Piersma, A.H.4
-
51
-
-
67650635159
-
Disentangling cellular proliferation and differentiation in the embryonic stem cell test, and its impact on the experimental protocol
-
van Dartel D.A.M., Zeijen N.J.L., de la Fonteyne L.J.J., van Schooten F.J., Piersma A.H. Disentangling cellular proliferation and differentiation in the embryonic stem cell test, and its impact on the experimental protocol. Reprod. Toxicol. 2009, 28:254-261.
-
(2009)
Reprod. Toxicol.
, vol.28
, pp. 254-261
-
-
van Dartel, D.A.M.1
Zeijen, N.J.L.2
de la Fonteyne, L.J.J.3
van Schooten, F.J.4
Piersma, A.H.5
-
52
-
-
3242791873
-
Discrimination of genotoxic from non-genotoxic carcinogens by gene expression profiling
-
van Delft J.H., van Agen E., van Breda S.G., Herwijnen M.H., Staal Y.C., Kleinjans J.C. Discrimination of genotoxic from non-genotoxic carcinogens by gene expression profiling. Carcinogenesis 2004, 25:1265-1276.
-
(2004)
Carcinogenesis
, vol.25
, pp. 1265-1276
-
-
van Delft, J.H.1
van Agen, E.2
van Breda, S.G.3
Herwijnen, M.H.4
Staal, Y.C.5
Kleinjans, J.C.6
-
54
-
-
0025647252
-
Biochemical basis for the activity and selectivity of oral antifungal drugs
-
Vanden Bossche H., Marichal P., Gorrens J., Coene M.C. Biochemical basis for the activity and selectivity of oral antifungal drugs. Br. J. Clin. Pract. Suppl. 1990, 71:41-46.
-
(1990)
Br. J. Clin. Pract. Suppl.
, vol.71
, pp. 41-46
-
-
Vanden Bossche, H.1
Marichal, P.2
Gorrens, J.3
Coene, M.C.4
-
55
-
-
42949123553
-
Transcriptional profiling reveals barcode-like toxicogenomic responses in the zebrafish embryo
-
Yang L., Kemadjou J.R., Zinsmeister C., Bauer M., Legradi J., Muller F., Pankratz M., Jakel J., Strahle U. Transcriptional profiling reveals barcode-like toxicogenomic responses in the zebrafish embryo. Genome Biol. 2007, 8:R227.
-
(2007)
Genome Biol.
, vol.8
-
-
Yang, L.1
Kemadjou, J.R.2
Zinsmeister, C.3
Bauer, M.4
Legradi, J.5
Muller, F.6
Pankratz, M.7
Jakel, J.8
Strahle, U.9
-
56
-
-
0037351102
-
Azole fungicides affect mammalian steroidogenesis by inhibiting sterol 14 alpha-demethylase and aromatase
-
Zarn J.A., Bruschweiler B.J., Schlatter J.R. Azole fungicides affect mammalian steroidogenesis by inhibiting sterol 14 alpha-demethylase and aromatase. Environ. Health Perspect. 2003, 111:255-261.
-
(2003)
Environ. Health Perspect.
, vol.111
, pp. 255-261
-
-
Zarn, J.A.1
Bruschweiler, B.J.2
Schlatter, J.R.3
|