Altered gene profiles in fetal rat testes after in utero exposure to Di(n-butyl) phthalate

Toxicological Sciences

Volumn 64, Issue 2, 2001, Pages 233-242

  Shultz, Valerie D ^a,b   Phillips, Suzanne ^a   Sar, Madhabananda ^a   Foster, Paul M D ^a   Gaido, Kevin W ^a  

^a CIIT CENTERS FOR HEALTH RESEARCH   (United States)

^b Sanofi Research Division   (United States)

Author keywords

Androgen receptor; Antiandrogen; cDNA microarray; Di(n butyl) phthalate; In utero exposure; Male reproductive development; Molecular mechanisms; Phthalate

Indexed keywords

ANDROGEN RECEPTOR; ANDROSTENEDIONE; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); CORN OIL; CYTOCHROME P450; FLUTAMIDE; MESSENGER RNA; PHTHALIC ACID DIBUTYL ESTER; PROGESTERONE; PROTEIN BCL 2; STEM CELL FACTOR RECEPTOR; STEROIDOGENIC ACUTE REGULATORY PROTEIN; TESTOSTERONE;

ANIMAL TISSUE; ARTICLE; CELL DEGENERATION; CELL HYPERPLASIA; CELL SURVIVAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA MICROARRAY; EXPOSURE; FEEDING; FETUS; GENE EXPRESSION; GENITAL SYSTEM; IN VITRO STUDY; LEYDIG CELL; MALE; NONHUMAN; PREGNANCY; PROTEIN INTERACTION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SERTOLI CELL; STEROIDOGENESIS; TESTIS; TESTOSTERONE SYNTHESIS;

ANDROGEN ANTAGONISTS; ANIMALS; CLUSTERIN; DIBUTYL PHTHALATE; FEMALE; FETUS; FLUTAMIDE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLYCOPROTEINS; IMMUNOHISTOCHEMISTRY; MALE; MATERNAL EXPOSURE; MOLECULAR CHAPERONES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; PROTO-ONCOGENE PROTEINS C-BCL-2; RADIOIMMUNOASSAY; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TESTIS; UTERUS;

ANIMALIA; ZEA MAYS;

EID: 0035194978     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/64.2.233     Document Type: Article

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