메뉴 건너뛰기




Volumn 3, Issue 5, 2001, Pages 241-249

E2F transcription factors and cancer

Author keywords

Apoptosis.; Cancer; E2F

Indexed keywords


EID: 84865402763     PISSN: 1699048X     EISSN: 16993055     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (4)

References (102)
  • 1
    • 0034679092 scopus 로고    scopus 로고
    • Molecular horizons of cancer therapeutics 11th Pezcoller Symposium
    • Avantaggiati ML. Molecular horizons of cancer therapeutics 11th Pezcoller Symposium. Biochim Biophys Acta 2000; 1.470: R49-R59.
    • (2000) Biochim Biophys Acta , vol.1 , Issue.470
    • Avantaggiati, M.L.1
  • 2
    • 0033666776 scopus 로고    scopus 로고
    • Role of the p53-homologue p73 in E2F-1 - Induced apoptosis
    • Stiewe T, Pützer B. Role of the p53-homologue p73 in E2F-1 - induced apoptosis. Nature Genetics 2000; 26: 464-469.
    • (2000) Nature Genetics , vol.26 , pp. 464-469
    • Stiewe, T.1    Pützer, B.2
  • 4
    • 0028053581 scopus 로고
    • Cell cycle checkpoints
    • Murray A. Cell cycle checkpoints. Curr Opin Cell Biol 1994; 6: 872-876.
    • (1994) Curr Opin Cell Biol , vol.6 , pp. 872-876
    • Murray, A.1
  • 5
    • 0032732260 scopus 로고    scopus 로고
    • Cell proliferation and apoptosis
    • Guo M, Hay B. Cell proliferation and apoptosis. Curr Opin Cell Biol 1999; 11: 745-752.
    • (1999) Curr Opin Cell Biol , vol.11 , pp. 745-752
    • Guo, M.1    Hay, B.2
  • 6
    • 0028568315 scopus 로고
    • Cell cycle control and cancer
    • Hartwell L, Kastan M. Cell cycle control and cancer. Science 1994; 266: 1.821-1.828.
    • (1994) Science , vol.26 , pp. 1821-1828
    • Hartwell, L.1    Kastan, M.2
  • 7
    • 0004712755 scopus 로고    scopus 로고
    • Latchman DS, ed Apoptosis and CellCycle Control in Cancer. London: BIOS Scientific Publishers
    • Peters G, Bates S, Parry D. The D-cyclins, their kinases and their inhibitors. In: Latchman DS, ed. Apoptosis and CellCycle Control in Cancer. London: BIOS Scientific Publishers, 1996; 37-53.
    • (1996) The D-cyclins, Their Kinases and Their Inhibitors , pp. 37-53
    • Peters, G.1    Bates, S.2    Parry, D.3
  • 8
    • 0345054420 scopus 로고
    • Purification of maturation- promoting factor, an intracellular regulator of early mitotic events
    • Lohka MJ, Hayes MK, Maller JL. Purification of maturation- promoting factor, an intracellular regulator of early mitotic events. Proc Natl Acad Sci USA 1988; 85: 3.009-3.013.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 3009-3013
    • Lohka, M.J.1    Hayes, M.K.2    Maller, J.L.3
  • 9
    • 0023753715 scopus 로고
    • The xenopus cdc 2 protein is a component of MPF, a cytoplasmic regulator of mitosis
    • Dunphay W, Brisuela L, Beach D, Newport J. The xenopus cdc 2 protein is a component of MPF, a cytoplasmic regulator of mitosis. Cell 1988; 54: 423- 431.
    • (1988) Cell , vol.54 , pp. 423-431
    • Dunphay, W.1    Brisuela, L.2    Beach, D.3    Newport, J.4
  • 10
    • 0025936510 scopus 로고
    • Cdc 25 is a specific tyrosine phosphatase that directly activates p34cdc 2
    • Gautier J, Solomon MJ, Booher RN, Bazan JF, Kirschner MW. cdc 25 is a specific tyrosine phosphatase that directly activates p34cdc 2. Cell 1991; 67: 197-211.
    • (1991) Cell , vol.67 , pp. 197-211
    • Gautier, J.1    Solomon, M.J.2    Booher, R.N.3    Bazan, J.F.4    Kirschner, M.W.5
  • 11
    • 0028332528 scopus 로고
    • The decision to enter mitosis
    • Dunphy WG. The decision to enter mitosis. Trends Cell Biol 1994; 4: 202-207
    • (1994) Trends Cell Biol , vol.4 , pp. 202-207
    • Dunphy, W.G.1
  • 12
    • 0035252894 scopus 로고    scopus 로고
    • Protein phosphatase 2A: A highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling
    • Janssens V, Goris J. Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling. Biochem J 2001; 353: 417-439.
    • (2001) Biochem J , vol.353 , pp. 417-439
    • Janssens, V.1    Goris, J.2
  • 13
    • 0032437776 scopus 로고    scopus 로고
    • Role of the retinoblastoma protein family, pRb, p107 and p130 in the negative control of cell growth
    • Graña X, Garriga J, Mayol X. Role of the retinoblastoma protein family, pRb, p107 and p130 in the negative control of cell growth. Oncogene 1998; 17: 3.365-3.383.
    • (1998) Oncogene , vol.17 , pp. 3365-3383
    • Graña, X.1    Garriga, J.2    Mayol, X.3
  • 14
    • 0034708554 scopus 로고    scopus 로고
    • Distinct versus redundant properties among members of the INK4 family of cyclin-dependent kinase inhibitors
    • Thullberg M, Bartkova J, Khan S, et al. Distinct versus redundant properties among members of the INK4 family of cyclin-dependent kinase inhibitors. FEBS Letters 2000; 470: 161-166.
    • (2000) FEBS Letters , vol.470 , pp. 161-166
    • Thullberg, M.1    Bartkova, J.2    Khan, S.3
  • 15
    • 0026652346 scopus 로고
    • A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F
    • Helin K, Lees JA, Vidal M, Dyson N, Harlow E, Fattaey A. A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F. Cell 1992; 70: 337-350.
    • (1992) Cell , vol.70 , pp. 337-350
    • Helin, K.1    Lees, J.A.2    Vidal, M.3    Dyson, N.4    Harlow, E.5    Fattaey, A.6
  • 16
    • 0026766083 scopus 로고
    • Expression cloning of a cDNA encoding a retinoblastoma binding protein with E2F-like properties
    • Kaelin WG Jr, Sellers WR, DeCaprio JA, et al. Expression cloning of a cDNA encoding a retinoblastoma binding protein with E2F-like properties. Cell 1992; 70: 351-364.
    • (1992) Cell , vol.70 , pp. 351-364
    • Kaelin Jr., W.G.1    Sellers, W.R.2    Decaprio, J.A.3
  • 17
    • 0027367144 scopus 로고
    • Cloning and characterization of E2F-2, a novel protein with the biochemical properties of transcription factor E2F
    • Ivey-Hoyle M, Conroy R, Huber H, Goodhart P, Oliff A, Heinbrook DC. Cloning and characterization of E2F-2, a novel protein with the biochemical properties of transcription factor E2F. Mol Cell Biol 1993; 13: 7.802-7.812.
    • (1993) Mol Cell Biol , vol.13 , pp. 7802-7812
    • Ivey-Hoyle, M.1    Conroy, R.2    Huber, H.3    Goodhart, P.4    Oliff, A.5    Heinbrook, D.C.6
  • 18
    • 0027362625 scopus 로고
    • The retinoblastoma protein binds to a family of E2F transcription factors
    • Lees JA, Saito M, Vidal M, et al. The retinoblastoma protein binds to a family of E2F transcription factors. Mol Cell Biol 1993; 13: 7.813-7.825.
    • (1993) Mol Cell Biol , vol.13 , pp. 7813-7825
    • Lees, J.A.1    Saito, M.2    Vidal, M.3
  • 19
  • 20
    • 0028148858 scopus 로고    scopus 로고
    • E2F-4, a new member of the E2F transcription factor family, interacts with p107
    • Ginsberg D, Vairo G, Chittenden T, et al. E2F-4, a new member of the E2F transcription factor family, interacts with p107. Genes & Dev. 8: 2.665- 2.679.
    • Genes & Dev , vol.8 , Issue.2 , pp. 665-2679
    • Ginsberg, D.1    Vairo, G.2    Chittenden, T.3
  • 21
    • 0028948866 scopus 로고
    • E2F-4 and E2F-5, two novel members of the E2F family, are expressed in the early phases of the cell cycle
    • Sardet C, Vidal M, Cobrinik D, et al. E2F-4 and E2F-5, two novel members of the E2F family, are expressed in the early phases of the cell cycle. Proc Natl Acad Sci 1995; 92: 2.403-2.407.
    • (1995) Proc Natl Acad Sci , vol.92 , pp. 2403-2407
    • Sardet, C.1    Vidal, M.2    Cobrinik, D.3
  • 24
    • 0032490832 scopus 로고    scopus 로고
    • E2F-6: A novel member of the E2F family is an inhibitor of E2F-dependent transcription
    • in press
    • Cartwright P, Müller H, Wagener C, Holm K, Helin K. E2F-6: A novel member of the E2F family is an inhibitor of E2F-dependent transcription. Oncogene 1998; 16 (in press).
    • (1998) Oncogene , vol.16
    • Cartwright, P.1    Müller, H.2    Wagener, C.3    Holm, K.4    Helin, K.5
  • 26
    • 0027512510 scopus 로고
    • A new component of the transcription factor DRTF1/E2F
    • Girling R, Partridge JF, Bandara LR, et al. A new component of the transcription factor DRTF1/E2F. Nature 1993; 362: 83-87.
    • (1993) Nature , vol.362 , pp. 83-87
    • Girling, R.1    Partridge, J.F.2    Bandara, L.R.3
  • 28
  • 29
    • 0028362359 scopus 로고
    • Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase
    • Krek W, Ewen ME, Shirodkar S, Arany ZZ, KaelinWG, Livingston D. Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase. Cell 1994; 78: 161-172.
    • (1994) Cell , vol.78 , pp. 161-172
    • Krek, W.1    Ewen, M.E.2    Shirodkar, S.3    Arany, Z.Z.4    Kaelin, W.G.5    Livingston, D.6
  • 30
    • 0028019279 scopus 로고
    • Cyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA-binding activity of E2F-1/DP-1 by phosphorylation
    • Xu M, Sheppard KA, Peng CY, Yee AS, Piwnica- Worms H. Cyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA-binding activity of E2F-1/DP-1 by phosphorylation. Mol Cell Biol 1994; 14: 8.420- 8.431.
    • (1994) Mol Cell Biol , vol.14 , pp. 8420-8431
    • Xu, M.1    Sheppard, K.A.2    Peng, C.Y.3    Yee, A.S.4    Piwnica- Worms, H.5
  • 32
    • 0029991715 scopus 로고    scopus 로고
    • Nuclear localization of DP and E2F transcription factors by heterodimeric partners and retinoblastoma protein family members
    • Magae J, Wu C-L, Illenye S, Harlow E, Heintz NH. Nuclear localization of DP and E2F transcription factors by heterodimeric partners and retinoblastoma protein family members. J Cell Sci 1996; 109: 1.717-1.726.
    • (1996) J Cell Sci , vol.10 , pp. 1717-1726
    • Magae, J.1    Wu, C.-L.2    Illenye, S.3    Harlow, E.4    Heintz, N.H.5
  • 33
    • 0030667320 scopus 로고    scopus 로고
    • E2F activity is regulated by cell-cycledependent changes in subcellular localization
    • Verona R, Moberg K, Estes S, Starz M, Vernon JP, Lees JA. E2F activity is regulated by cell-cycledependent changes in subcellular localization. Mol Cell Biol 1997; 17: 7.268-7.282.
    • (1997) Mol Cell Biol , vol.17 , pp. 7268-7282
    • Verona, R.1    Moberg, K.2    Estes, S.3    Starz, M.4    Vernon, J.P.5    Lees, J.A.6
  • 34
    • 0029926303 scopus 로고    scopus 로고
    • Interaction of Sp 1 with the growth- and cell cycle-regulated transcription factor E2F
    • Karlseder J, Rotheneder H, Wintersberger E. Interaction of Sp 1 with the growth- and cell cycle-regulated transcription factor E2F. Mol Cell Biol 1996; 16:1.659-1.667.
    • (1996) Mol Cell Biol , vol.16 , pp. 1659-1667
    • Karlseder, J.1    Rotheneder, H.2    Wintersberger, E.3
  • 35
    • 0029981560 scopus 로고    scopus 로고
    • Cell cycle-regulated association of E2F- 1 and Sp 1 is related to their functional interaction
    • Lin S-Y, Black AR, Kostic D, Pajovic S, Hoover CN, Azizkhan JC. Cell cycle-regulated association of E2F- 1 and Sp 1 is related to their functional interaction. Mol Cell Biol 1996; 16: 1.668-1.675.
    • (1996) Mol Cell Biol , vol.16 , pp. 1668-1675
    • Lin, S.-Y.1    Black, A.R.2    Kostic, D.3    Pajovic, S.4    Hoover, C.N.5    Azizkhan, J.C.6
  • 36
    • 0002673218 scopus 로고    scopus 로고
    • Ghysdael J Yaniv M, eds. Oncogenes as transcriptional regulators. Berlin, Germany: Birkhauser Verlag
    • Sardet C, LeCam L, Fabbrizio E, Vidal M. E2F and the retinoblastoma protein family. In: Ghysdael J, Yaniv M, eds. Oncogenes as transcriptional regulators. Berlin, Germany: Birkhauser Verlag, 1997; 2: 1-63.
    • (1997) E2F and the Retinoblastoma Protein Family , vol.2 , pp. 1-63
    • Sardet, C.1    Lecam, L.2    Fabbrizio, E.3    Vidal, M.4
  • 37
    • 0032482981 scopus 로고    scopus 로고
    • Unusual proliferation arrest and transcriptional control properties of a newly discovered E2F family member
    • Gaubatz S, Wood JG, Livingston DM. Unusual proliferation arrest and transcriptional control properties of a newly discovered E2F family member, E2F-6. Proc Natl Acad Sci USA 1998; 95: 9.190- 9.195.
    • (1998) E2F-6. Proc Natl Acad Sci USA , vol.95 , pp. 9190-9195
    • Gaubatz, S.1    Wood, J.G.2    Livingston, D.M.3
  • 38
    • 0034644194 scopus 로고    scopus 로고
    • Identification of E2F-3B, an alternative form of E2F- 3 lacking a conserved N-terminal region
    • He Y, Armanious MK, Thomas MJ, Cress WD. Identification of E2F-3B, an alternative form of E2F- 3 lacking a conserved N-terminal region. Oncogene 2000; 13, 19 (30): 3.422-3.433.
    • (2000) Oncogene , vol.13 , Issue.19 , pp. 3422-3430
    • He, Y.1    Armanious, M.K.2    Thomas, M.J.3    Cress, W.D.4
  • 40
    • 0037998134 scopus 로고    scopus 로고
    • The E2F transcription factors: Key regulators of cell proliferation
    • Muller H, Helin K. The E2F transcription factors: key regulators of cell proliferation. Biochim Biophys Acta 2000; 1.470: M1-M12.
    • (2000) Biochim Biophys Acta , vol.1 , Issue.470
    • Muller, H.1    Helin, K.2
  • 41
    • 0034123243 scopus 로고    scopus 로고
    • Expression of the E2F family of transcription factors during murine development
    • Kusek JC, Greene RM, Nugent P, Pisano MM. Expression of the E2F family of transcription factors during murine development. Int J Dev Biol 2000; 44 (3): 267-277.
    • (2000) Int J Dev Biol , vol.44 , Issue.3 , pp. 267-277
    • Kusek, J.C.1    Greene, R.M.2    Nugent, P.3    Pisano, M.M.4
  • 42
    • 0034646630 scopus 로고    scopus 로고
    • E2F family members are differentially regulated by reversible acetylation
    • 10892
    • Marzio G, Wagener C, Gutiérrez MI, Cartwright P, Helin K, Giacca M. E2F family members are differentially regulated by reversible acetylation. J Biol Chem 2000; 275 (15): 10.887-10.892.
    • (2000) J Biol Chem , vol.275 , Issue.15 , pp. 10887-10915
    • Marzio, G.1    Wagener, C.2    Gutiérrez, M.I.3    Cartwright, P.4    Helin, K.5    Giacca, M.6
  • 44
    • 0029949784 scopus 로고    scopus 로고
    • E2F-1 functions in mice to promote apoptosis and suppress proliferation
    • Field S, Tsai F, Kuo F, et al. E2F-1 functions in mice to promote apoptosis and suppress proliferation. Cell 1996; 85: 549-561.
    • (1996) Cell , vol.85 , pp. 549-561
    • Field, S.1    Tsai, F.2    Kuo, F.3
  • 46
    • 0029033861 scopus 로고
    • The retinoblastoma protein and cell cycle control
    • Weinberg RA. The retinoblastoma protein and cell cycle control. Cell 1995; 81: 323-330.
    • (1995) Cell , vol.81 , pp. 323-330
    • Weinberg, R.A.1
  • 47
    • 0029977751 scopus 로고    scopus 로고
    • E2F and cell proliferation: A world turned upside down
    • Weinberg RA. E2F and cell proliferation: a world turned upside down. Cell 1996; 85: 457-459.
    • (1996) Cell , vol.85 , pp. 457-459
    • Weinberg, R.A.1
  • 48
    • 0033602410 scopus 로고    scopus 로고
    • Balancing proliferation and apoptosis in vivo: The goldilocks theory of E2F/DP action
    • Yamasaki L. Balancing proliferation and apoptosis in vivo: the goldilocks theory of E2F/DP action. Biochim Biophys Acta 1999; 1423: M9-M15.
    • (1999) Biochim Biophys Acta , vol.1423
    • Yamasaki, L.1
  • 49
    • 0032504783 scopus 로고    scopus 로고
    • P14ARF links the tumour suppressors RB and p53
    • Bates S, Phillips AC, Clark PA, et al. p14ARF links the tumour suppressors RB and p53. Nature 1998; 395: 124- 125.
    • (1998) Nature , vol.395 , pp. 124-125
    • Bates, S.1    Phillips, A.C.2    Clark, P.A.3
  • 50
    • 0035836772 scopus 로고    scopus 로고
    • P19ARF targets certain E2F species for degradation
    • 4460
    • Martelli F, Hamilton T, Silver DP, et al. p19ARF targets certain E2F species for degradation. Proc Natl Acad Sci USA 2001; 98 (8): 4.455-4.460.
    • (2001) Proc Natl Acad Sci USA , vol.98 , Issue.8 , pp. 4455-4458
    • Martelli, F.1    Hamilton, T.2    Silver, D.P.3
  • 51
    • 0033622003 scopus 로고    scopus 로고
    • P16INK4A and p19ARF act in overlapping pathways in cellular immortalization
    • Carner A, Hudson JD, Price CM, Beach DH. p16INK4A and p19ARF act in overlapping pathways in cellular immortalization. Nat Cell Biol 2000; 2 (3): 148-155.
    • (2000) Nat Cell Biol , vol.2 , Issue.3 , pp. 148-155
    • Carner, A.1    Hudson, J.D.2    Price, C.M.3    Beach, D.H.4
  • 52
    • 0034609798 scopus 로고    scopus 로고
    • Role for the p53 homologue p73 in E2F-1-induced apoptosis
    • Irwin M, Marin MC, Phillips AC, et al. Role for the p53 homologue p73 in E2F-1-induced apoptosis. Nature 2000; 407: 645-648.
    • (2000) Nature , vol.407 , pp. 645-648
    • Irwin, M.1    Marin, M.C.2    Phillips, A.C.3
  • 53
    • 0033666773 scopus 로고    scopus 로고
    • P53 and p73: Seeing double?
    • Soengas M, Lowe S. p53 and p73: seeing double? Nat Genet 2000; 26: 391-392.
    • (2000) Nat Genet , vol.26 , pp. 391-392
    • Soengas, M.1    Lowe, S.2
  • 54
    • 0034609864 scopus 로고    scopus 로고
    • A common E2F-1 and p73 pathway mediates cell death induced by TCR activation
    • Lissy N, Davis P, Irwin M, Kaelin W, Dowdy S. A common E2F-1 and p73 pathway mediates cell death induced by TCR activation. Nature 2000; 407: 642-644.
    • (2000) Nature , vol.407 , pp. 642-644
    • Lissy, N.1    Davis, P.2    Irwin, M.3    Kaelin, W.4    Dowdy, S.5
  • 56
    • 0028909272 scopus 로고
    • Amplification of the E2F1 transcription factor gene in the HEL erythroleukemia cell line
    • Saito M, Helin K, Valentine MB, et al. Amplification of the E2F1 transcription factor gene in the HEL erythroleukemia cell line. Genomics 1995; 25 (1): 130-138.
    • (1995) Genomics , vol.25 , Issue.1 , pp. 130-138
    • Saito, M.1    Helin, K.2    Valentine, M.B.3
  • 58
    • 14444280359 scopus 로고    scopus 로고
    • Frequent mutation of the E2F-4 cell cycle gene in primary human gastrointestinal tumors
    • Souza RF, Yin J, Smolinski KN, et al. Cancer Research, Vol 57, Issue 12 2350-2353, Frequent mutation of the E2F-4 cell cycle gene in primary human gastrointestinal tumors.
    • Cancer Research , vol.57 , Issue.12 , pp. 2350-2353
    • Souza, R.F.1    Yin, J.2    Smolinski, K.N.3
  • 60
    • 0033777303 scopus 로고    scopus 로고
    • Microsatellite instability and alteration of E2F-4 gene in adenosquamous and squamous cell carcinomas of the stomach
    • Woo DK, Lee WA, Kim YI, Kim WH. Microsatellite instability and alteration of E2F-4 gene in adenosquamous and squamous cell carcinomas of the stomach. Pathol Int 2000;50 (9): 690-695.
    • (2000) Pathol Int , vol.50 , Issue.9 , pp. 690-695
    • Woo, D.K.1    Lee, W.A.2    Kim, Y.I.3    Kim, W.H.4
  • 61
    • 0034651638 scopus 로고    scopus 로고
    • Mutations of the E2F4 gene in haematological malignancies having microsatellite instability
    • 1510
    • Komatsu N, Takeuchi S, Ikezoe T, et al. Mutations of the E2F4 gene in haematological malignancies having microsatellite instability. Blood 2000; 95 (4): 1.509-1.510.
    • (2000) Blood , vol.95 , Issue.4 , pp. 1509-1514
    • Komatsu, N.1    Takeuchi, S.2    Ikezoe, T.3
  • 62
    • 0034017327 scopus 로고    scopus 로고
    • Genomic structure and mutation screening of the E2F4 gene in human tumors
    • Schwemmle S, Pfeifer GP. Genomic structure and mutation screening of the E2F4 gene in human tumors. Int J Cancer 20001; 86 (5): 672-677.
    • (2001) Int J Cancer , vol.86 , Issue.5 , pp. 672-677
    • Schwemmle, S.1    Pfeifer, G.P.2
  • 63
    • 0034070460 scopus 로고    scopus 로고
    • Human E2F5 gene is oncogenic in primary rodent cells and is amplified in human breast tumors
    • Polanowska J, Le Cam L, Orsetti B, et al. Human E2F5 gene is oncogenic in primary rodent cells and is amplified in human breast tumors. Genes Chromosomes Cancer 2000; 28 (1): 126-130.
    • (2000) Genes Chromosomes Cancer , vol.28 , Issue.1 , pp. 126-130
    • Polanowska, J.1    Le Cam, L.2    Orsetti, B.3
  • 64
    • 0033583822 scopus 로고    scopus 로고
    • Prognostic significance of transcription factor E2F-1 in bladder cancer: Genotypic and phenotypic characterization
    • Rabbani F, Richon VM, Orlow I, et al. Prognostic significance of transcription factor E2F-1 in bladder cancer: genotypic and phenotypic characterization. J Natl Cancer Inst 1999; 91; 874-881.
    • (1999) J Natl Cancer Inst , vol.91 , pp. 874-881
    • Rabbani, F.1    Richon, V.M.2    Orlow, I.3
  • 65
    • 0033951771 scopus 로고    scopus 로고
    • Mutation of cell cycle regulators and their impact on superficial bladder cancer
    • Rabbani F, Cordon-Cardo C. Mutation of cell cycle regulators and their impact on superficial bladder cancer. Urol Clin North Am 2000; 27 (1): 83-102.
    • (2000) Urol Clin North Am , vol.27 , Issue.1 , pp. 83-102
    • Rabbani, F.1    Cordon-Cardo, C.2
  • 66
    • 0034009592 scopus 로고    scopus 로고
    • Frequent disruption of the RB1 pathway in diffuse large B cell lymphoma: Prognostic significance of E2F-1 and p16INK4A
    • Moller MB, Kania PW, Ino Y, et al. Frequent disruption of the RB1 pathway in diffuse large B cell lymphoma: prognostic significance of E2F-1 and p16INK4A. Leukemia 2000; 14 (5): 898-904.
    • (2000) Leukemia , vol.14 , Issue.5 , pp. 898-904
    • Moller, M.B.1    Kania, P.W.2    Ino, Y.3
  • 67
    • 0343415553 scopus 로고    scopus 로고
    • Expression of cell-cycle-regulating transcription factor E2F-1 in colorectal carcinomas
    • Yasui W, Fujimoto J, Suzuki T, et al. Expression of cell-cycle-regulating transcription factor E2F-1 in colorectal carcinomas. Pathobiology 1999; 67 (4): 174-179.
    • (1999) Pathobiology , vol.67 , Issue.4 , pp. 174-179
    • Yasui, W.1    Fujimoto, J.2    Suzuki, T.3
  • 68
    • 2642607872 scopus 로고    scopus 로고
    • Clinical implications of cyclins, cyclin-dependent kinases, RB and E2F1 in squamous-cell lung carcinoma
    • Volm M, Koomagi R, Rittgen W. Clinical implications of cyclins, cyclin-dependent kinases, RB and E2F1 in squamous-cell lung carcinoma. Int J Cancer 1998; 79 (3): 294-299.
    • (1998) Int J Cancer , vol.79 , Issue.3 , pp. 294-299
    • Volm, M.1    Koomagi, R.2    Rittgen, W.3
  • 69
    • 0032111673 scopus 로고    scopus 로고
    • The gene expression index c-myc x E2F-1/p21 is highly predictive of malignant phenotype in human bronchial epithelial cells
    • DeMuth JP, Jackson CM, Weaver DA, et al. The gene expression index c-myc x E2F-1/p21 is highly predictive of malignant phenotype in human bronchial epithelial cells. Am J Respir Cell Mol Biol 1998;19(1):18-24.
    • (1998) Am J Respir Cell Mol Biol , vol.19 , Issue.1 , pp. 18-24
    • Demuth, J.P.1    Jackson, C.M.2    Weaver, D.A.3
  • 70
    • 0034327358 scopus 로고    scopus 로고
    • E2F-1 gene transfer enhances invasiveness of human head and neck carcinoma cell lines
    • 5976
    • Zhang SY, Liu SC, Johnson DG, Klein-Szanto AJ. E2F-1 gene transfer enhances invasiveness of human head and neck carcinoma cell lines. Cancer Res 2000; 60 (21): 5.972-5.976.
    • (2000) Cancer Res , vol.60 , Issue.21 , pp. 5972-6021
    • Zhang, S.Y.1    Liu, S.C.2    Johnson, D.G.3    Klein-Szanto, A.J.4
  • 71
    • 0031947357 scopus 로고    scopus 로고
    • Higher levels of thymidylate synthase gene expression are observed in pulmonary as compared with hepatic metastases of colorectal adenocarcinoma
    • Gorlick R, et al. Higher levels of thymidylate synthase gene expression are observed in pulmonary as compared with hepatic metastases of colorectal adenocarcinoma. J Clin Oncol 1998; 16: 1.465- 1.469.
    • (1998) J Clin Oncol , vol.16 , pp. 1465-1469
    • Gorlick, R.1
  • 73
    • 0034192487 scopus 로고    scopus 로고
    • Levels of E2F-1 expression are higher in lung metastasis of colon cancer as compared with hepatic metastasis and correlate with levels of thymidylate synthase
    • 2367
    • Banerjee D, Gorlick R, Liefshitz A, et al. Levels of E2F-1 expression are higher in lung metastasis of colon cancer as compared with hepatic metastasis and correlate with levels of thymidylate synthase. Cancer Res 2000; 60 (9): 2.365-2.367.
    • (2000) Cancer Res , vol.60 , Issue.9 , pp. 2365-2369
    • Banerjee, D.1    Gorlick, R.2    Liefshitz, A.3
  • 74
    • 0034689006 scopus 로고    scopus 로고
    • Deregulated E2F transcriptional activity in autonomously growing melanoma cells
    • 1016
    • Halaban R, Cheng E, Smicun Y, Germino J. Deregulated E2F transcriptional activity in autonomously growing melanoma cells. J Exp Med 2000; 191 (6): 1.005-1.016.
    • (2000) J Exp Med , vol.191 , Issue.6 , pp. 1005-1006
    • Halaban, R.1    Cheng, E.2    Smicun, Y.3    Germino, J.4
  • 75
    • 0033368549 scopus 로고    scopus 로고
    • Melanoma cell autonomous growth: The Rb/E2F pathway
    • Halaban R. Melanoma cell autonomous growth: the Rb/E2F pathway. Cancer Metastasis Rev 1999; 18 (3): 333-343.
    • (1999) Cancer Metastasis Rev , vol.18 , Issue.3 , pp. 333-343
    • Halaban, R.1
  • 77
    • 0033961809 scopus 로고    scopus 로고
    • Cyclin D1 is required for transformation by activated Neu and is ind u c e d through an E2F-dependent signalling pathway
    • Lee RJ, Albanese C, Fu M, et al. Cyclin D1 is required for transformation by activated Neu and is ind u c e d through an E2F-dependent signalling pathway. Mol Cell Biol 2000; 20 (2): 672-683.
    • (2000) Mol Cell Biol , vol.20 , Issue.2 , pp. 672-683
    • Lee, R.J.1    Albanese, C.2    Fu, M.3
  • 79
    • 0031749470 scopus 로고    scopus 로고
    • Overexpression of E2F-1 in glioma triggers apoptosis and suppresses tumor growth in vitro and in vivo
    • Fueyo J, Gómez-Manzano C, Yung WK, et al. Overexpression of E2F-1 in glioma triggers apoptosis and suppresses tumor growth in vitro and in vivo. Nat Med 1998; 4: 685-690.
    • (1998) Nat Med , vol.4 , pp. 685-690
    • Fueyo, J.1    Gómez-Manzano, C.2    Yung, W.K.3
  • 80
    • 0033091228 scopus 로고    scopus 로고
    • Apoptosis induction by E2F-1 via adenoviral-mediated gene transfer results in growth suppression of head and neck squamous cell carcinoma cell lines
    • Liu TJ, Wang M, Breau RL, et al. Apoptosis induction by E2F-1 via adenoviral-mediated gene transfer results in growth suppression of head and neck squamous cell carcinoma cell lines. Cancer Gene Ther 1999; 6: 163-171.
    • (1999) Cancer Gene Ther , vol.6 , pp. 163-171
    • Liu, T.J.1    Wang, M.2    Breau, R.L.3
  • 81
    • 0035141075 scopus 로고    scopus 로고
    • Development of cyclin-dependent kinase modulators as novel therapeutic approaches for hematological malignancies
    • Senderowicz AM. Development of cyclin-dependent kinase modulators as novel therapeutic approaches for hematological malignancies. Leukemia 2001; 15(1): 1-9.
    • (2001) Leukemia , vol.15 , Issue.1 , pp. 1-9
    • Senderowicz, A.M.1
  • 82
    • 0033646291 scopus 로고    scopus 로고
    • Flavopiridol, the first cyclin-dependent kinase inhibitor to enter the clinic: Current status
    • 2911
    • Kelland LR. Flavopiridol, the first cyclin-dependent kinase inhibitor to enter the clinic: current status. Expert Opin Invest Drugs 2000; 9 (12): 2.903- 2.911.
    • (2000) Expert Opin Invest Drugs , vol.9 , Issue.12 , pp. 2903-2912
    • Kelland, L.R.1
  • 83
    • 0032541640 scopus 로고    scopus 로고
    • Crystal structure of the complex of the cyclin D-dependent kinase Cdk6 bound to the cell-cycle inhibitor p19INK4d
    • Brotherton DH, Dhanaraj V, Wick S, et al. Crystal structure of the complex of the cyclin D-dependent kinase Cdk6 bound to the cell-cycle inhibitor p19INK4d. Nature 1998; 395 (6.699): 244-250.
    • (1998) Nature , vol.395 , Issue.6699 , pp. 244-250
    • Brotherton, D.H.1    Dhanaraj, V.2    Wick, S.3
  • 84
    • 0005686626 scopus 로고    scopus 로고
    • Changes in E2F binding after phenylbutyrate-induced differentiation of Caco-2 colon cancer cells
    • Wang QM, Feinman R, Kashanchi F, et al. Changes in E2F binding after phenylbutyrate-induced differentiation of Caco-2 colon cancer cells. Clin Cancer Res 2000; 6: 2.951-2.958.
    • (2000) Clin Cancer Res , vol.6 , Issue.2 , pp. 951-2958
    • Wang, Q.M.1    Feinman, R.2    Kashanchi, F.3
  • 85
    • 0029031549 scopus 로고
    • M orishita R, Gibbons GH, Horiuchi M, et al
    • M orishita R, Gibbons GH, Horiuchi M, et al. A gene therapy strategy using a transcription factor decoy of the E2F binding site inhibits smooth muscle proliferation in vivo. Proc Natl Acad Sci USA 1995; 92 (13): 5.855-5.859 86.
    • (1995) Proc Natl Acad Sci USA , vol.92 , Issue.13 , pp. 5855-5859
  • 86
    • 0033767577 scopus 로고    scopus 로고
    • Therapeutic applications of transcription factor decoy oligonucleotides
    • 1075
    • Mann MJ, Dzau VJ. Therapeutic applications of transcription factor decoy oligonucleotides. J Clin Invest 2000; 106 (9): 1.071-1.075.
    • (2000) J Clin Invest , vol.106 , Issue.9 , pp. 1071-1079
    • Mann, M.J.1    Dzau, V.J.2
  • 87
    • 0034711518 scopus 로고    scopus 로고
    • Gene therapy for attenuating cardiac allograft arteriopathy using ex vivo E2F decoy transfection by HVJ-AVE-liposome method in mice and nonhuman primates
    • 1068
    • Kawauchi M, Suzuki J, Morishita R, et al. Gene therapy for attenuating cardiac allograft arteriopathy using ex vivo E2F decoy transfection by HVJ-AVE-liposome method in mice and nonhuman primates. Circ Res 2000; 87 (11): 1.063-1.068.
    • (2000) Circ Res , vol.87 , Issue.11 , pp. 1063-1111
    • Kawauchi, M.1    Suzuki, J.2    Morishita, R.3
  • 88
    • 0035323907 scopus 로고    scopus 로고
    • Longterm stabilization of vein graft wall architecture and prolonged resistance to experimental atherosclerosis after E2F decoy oligonucleotide gene therapy
    • Ehsan A, Mann MJ, Dell'Acqua G, Dzau VJ. Longterm stabilization of vein graft wall architecture and prolonged resistance to experimental atherosclerosis after E2F decoy oligonucleotide gene therapy. J Thorac Cardiovasc Surg 2001; 121 (4): 714-722.
    • (2001) J Thorac Cardiovasc Surg , vol.121 , Issue.4 , pp. 714-722
    • Ehsan, A.1    Mann, M.J.2    Dell'Acqua, G.3    Dzau, V.J.4
  • 89
    • 0035219555 scopus 로고    scopus 로고
    • Gene therapy for arteriosclerotic diseases
    • Aoki M, Morishita R, Ogihara T. Gene therapy for arteriosclerotic diseases. Nippon Rinsho 2001; 59 (1): 43-52.
    • (2001) Nippon Rinsho , vol.59 , Issue.1 , pp. 43-52
    • Aoki, M.1    Morishita, R.2    Ogihara, T.3
  • 91
    • 6544264325 scopus 로고    scopus 로고
    • Intratumoral injection of oligonucleotides to the NF kappa B binding site inhibits cachexia in a mouse tumor model
    • Kawamura I, Morishita R, Tomita N, et al. Intratumoral injection of oligonucleotides to the NF kappa B binding site inhibits cachexia in a mouse tumor model. Gene Ther 1999; 6 (1): 91-97.
    • (1999) Gene Ther , vol.6 , Issue.1 , pp. 91-97
    • Kawamura, I.1    Morishita, R.2    Tomita, N.3
  • 93
    • 0035272741 scopus 로고    scopus 로고
    • A new class of cytotoxic DNA minor groove binders: Alfa-halogenoacrylic derivatives of pyrrolecarbamoyl oligomers
    • Cozzi P. A new class of cytotoxic DNA minor groove binders: alfa-halogenoacrylic derivatives of pyrrolecarbamoyl oligomers. Farmaco 2001; 56 (1- 2): 57-65.
    • (2001) Farmaco , vol.56 , Issue.1-2 , pp. 57-65
    • Cozzi, P.1
  • 94
    • 0033869428 scopus 로고    scopus 로고
    • Improved safety through tamoxifen-regulated induction of cytotoxic genes delivered by Ad vectors for cancer gene therapy
    • 1325
    • Putzer BM, Stiewe T, Crespo F, Esche H. Improved safety through tamoxifen-regulated induction of cytotoxic genes delivered by Ad vectors for cancer gene therapy. Gene Ther 2000; 7 (15): 1.317- 1.325.
    • (2000) Gene Ther , vol.7 , Issue.15 , pp. 1317-1415
    • Putzer, B.M.1    Stiewe, T.2    Crespo, F.3    Esche, H.4
  • 95
    • 0344287260 scopus 로고    scopus 로고
    • Adenovirusmediated E2F-1 gene transfer efficiently induces apoptosis in melanoma cells
    • 2033
    • Dong YB, Yang HL, Elliott MJ, et al. Adenovirusmediated E2F-1 gene transfer efficiently induces apoptosis in melanoma cells. Cancer 1999; 86 (10): 2.021-2.033.
    • (1999) Cancer , vol.86 , Issue.10 , pp. 2021-2110
    • Dong, Y.B.1    Yang, H.L.2    Elliott, M.J.3
  • 96
    • 0034223146 scopus 로고    scopus 로고
    • Adenovirusmediated E2F-1 gene transfer induces an apoptotic response in human gastric carcinoma cells that is enhanced by cyclin dependent kinase inhibitors
    • Atienza C Jr, Elliott MJ, Dong YB, et al. Adenovirusmediated E2F-1 gene transfer induces an apoptotic response in human gastric carcinoma cells that is enhanced by cyclin dependent kinase inhibitors. Int J Mol Med 2000; 6 (1): 55-63.
    • (2000) Int J Mol Med , vol.6 , Issue.1 , pp. 55-63
    • Atienza Jr., C.1    Elliott, M.J.2    Dong, Y.B.3
  • 98
    • 0000303284 scopus 로고    scopus 로고
    • Caspase activation and changes in Bcl-2 family member protein expression associated with E2F-1- mediated apoptosis in human esophageal cancer cells
    • 1589
    • Yang HL, Dong YB, Elliott MJ, Liu TJ, McMasters KM. Caspase activation and changes in Bcl-2 family member protein expression associated with E2F-1- mediated apoptosis in human esophageal cancer cells. Clin Cancer Res 2000; 6 (4): 1.579-1.589.
    • (2000) Clin Cancer Res , vol.6 , Issue.4 , pp. 1579-1584
    • Yang, H.L.1    Dong, Y.B.2    Elliott, M.J.3    Liu, T.J.4    McMasters, K.M.5
  • 99
    • 0242484074 scopus 로고    scopus 로고
    • Adenovirusmediated E2F-1 gene transfer inhibits MDM2 expression and efficiently induces apoptosis in MDM2-overexpressing tumor cells
    • 2242-8
    • Yang HL, Dong YB, Elliott MJ, et al. Adenovirusmediated E2F-1 gene transfer inhibits MDM2 expression and efficiently induces apoptosis in MDM2-overexpressing tumor cells. Clin Cancer Res 1999; 5 (8): 2.242-2.250.
    • (1999) Clin Cancer Res , vol.5 , Issue.8 , pp. 2250
    • Yang, H.L.1    Dong, Y.B.2    Elliott, M.J.3
  • 100
    • 0033614968 scopus 로고    scopus 로고
    • Inhibition of mammalian cell proliferation by genetically selected peptide aptamers that funtiolally antagonize E2F activity
    • Fabbrizio E, Le Cam L, Polanowska J, et al. Inhibition of mammalian cell proliferation by genetically selected peptide aptamers that funtiolally antagonize E2F activity. Oncogene 1999; 18: 4.357-4.363.
    • (1999) Oncogene , vol.18 , pp. 4357-4363
    • Fabbrizio, E.1    Le Cam, L.2    Polanowska, J.3
  • 101
    • 0027434084 scopus 로고
    • Functional synergy between DP-1 and E2F-1 in the cell cycle-regulating transcription factor DRTF1/E2F
    • Bandara LR, Buck VM, Zamanian M, Johnston LH, La Thanguc NB. Functional synergy between DP-1 and E2F-1 in the cell cycle-regulating transcription factor DRTF1/E2F. EMBO J 1993; 12: 4.317-4.324.
    • (1993) EMBO J , vol.12 , pp. 4317-4324
    • Bandara, L.R.1    Buck, V.M.2    Zamanian, M.3    Johnston, L.H.4    La Thanguc, N.B.5
  • 102
    • 0035260519 scopus 로고    scopus 로고
    • Co-expression of E2F-2 enhances the p53 anticancer effect in human glioma cells
    • Mitlianga PG, Kyritsis AP, Gomez-Manzano C, et al. Co-expression of E2F-2 enhances the p53 anticancer effect in human glioma cells. Int J Oncol 2001; 18 (2): 343-347.
    • (2001) Int J Oncol , vol.18 , Issue.2 , pp. 343-347
    • Mitlianga, P.G.1    Kyritsis, A.P.2    Gomez-Manzano, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.