Inhibition of mammalian cell proliferation by genetically selected peptide aptamers that functionally antagonize E2F activity

Oncogene

Volumn 18, Issue 30, 1999, Pages 4357-4363

  Fabbrizio, Eric ^a   Le Cam, Laurent ^a   Polanowska, Jolanta ^a   Kaczorek, Michel ^b   Lamb, Ned ^c   Brent, Roger ^d   Sardet, Claude ^a  

^a INSTITUT DE GÉNÉTIQUE MOLÉCULAIRE DE MONTPELLIER   (France)

^b Synt:em Parc Sci Georges Besse F   (France)

^c INSTITUTE OF HUMAN GENETICS   (France)

^d The Molecular Sciences Institute   (United States)

Author keywords

Cell proliferation; DNA binding and dimerization domains; E2F transcription factors; Peptidic inhibitors

Indexed keywords

CELL PROTEIN; CYCLINE; PROTEIN P16; SYNTHETIC PEPTIDE; TRANSCRIPTION FACTOR E2F;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL ACTIVITY; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; DEREGULATION; DIMERIZATION; DNA BINDING; DNA REPLICATION; FIBROBLAST; HUMAN; HUMAN CELL; MAMMAL CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM;

AMINO ACID SEQUENCE; ANIMALS; CARRIER PROTEINS; CELL CYCLE PROTEINS; CELL DIVISION; CELL LINE; CRICETINAE; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; E2F TRANSCRIPTION FACTORS; FIBROBLASTS; FLUORESCENT ANTIBODY TECHNIQUE; G1 PHASE; GROWTH INHIBITORS; HUMANS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; PEPTIDES; S PHASE; THIOREDOXIN; TRANSCRIPTION FACTOR DP1; TRANSCRIPTION FACTORS;

EID: 0033614968     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1202825     Document Type: Article

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