-
1
-
-
0030795068
-
Translational enhancement of mdm2 oncogene expression in human tumor cells containing a stabilized wild-type p53 protein
-
Landers, J. E., Cassel, S. L., and George, D. L. Translational enhancement of mdm2 oncogene expression in human tumor cells containing a stabilized wild-type p53 protein. Cancer Res., 57: 3562-3568, 1997.
-
(1997)
Cancer Res.
, vol.57
, pp. 3562-3568
-
-
Landers, J.E.1
Cassel, S.L.2
George, D.L.3
-
2
-
-
0027232042
-
p53 Mutation, and MDM2 amplification in human soft tissue sarcomas
-
Leach, F. S., Tokino, T., Meltzer, P., Burrell, M., Oliner, J. D., Smith, S., Hill, D. E., Sidransky, D., Kinzler, K. W., and Vogelstein, B. p53 Mutation, and MDM2 amplification in human soft tissue sarcomas. Cancer Res., 53: 2231-2234, 1993.
-
(1993)
Cancer Res.
, vol.53
, pp. 2231-2234
-
-
Leach, F.S.1
Tokino, T.2
Meltzer, P.3
Burrell, M.4
Oliner, J.D.5
Smith, S.6
Hill, D.E.7
Sidransky, D.8
Kinzler, K.W.9
Vogelstein, B.10
-
3
-
-
0027325132
-
Oncoprotein MDM2 conceals the activation domain of tumor suppressor p53
-
Oliner, J. D., Pietenpol, J. A., Thiagalingam, S., Gyuris, J., Kinzler, K. W., and Vogelstein, B. Oncoprotein MDM2 conceals the activation domain of tumor suppressor p53. Nature (Lond.), 362: 857-860, 1993.
-
(1993)
Nature (Lond.)
, vol.362
, pp. 857-860
-
-
Oliner, J.D.1
Pietenpol, J.A.2
Thiagalingam, S.3
Gyuris, J.4
Kinzler, K.W.5
Vogelstein, B.6
-
4
-
-
0028098165
-
Molecular abnormalities of mdm2 and p53 genes in adult soft tissue sarcomas
-
Cordon-Cardo, C., Latres, E., Drobnjak, M., Oliva, M. R., Pollack, D., Woodruff, J. M., Marechal, V., Chen, J., Brennan, M. F., and Levine, A. J. Molecular abnormalities of mdm2 and p53 genes in adult soft tissue sarcomas. Cancer Res., 54: 794-799, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 794-799
-
-
Cordon-Cardo, C.1
Latres, E.2
Drobnjak, M.3
Oliva, M.R.4
Pollack, D.5
Woodruff, J.M.6
Marechal, V.7
Chen, J.8
Brennan, M.F.9
Levine, A.J.10
-
5
-
-
0027508958
-
MDM2 gene amplification in metastatic osteosarcoma
-
Ladanyi, M., Cha, C., Lewis, R., Jhanwar, S. C., Huvos, A. G., and Healey, J. H. MDM2 gene amplification in metastatic osteosarcoma. Cancer Res., 53: 16-18, 1993.
-
(1993)
Cancer Res.
, vol.53
, pp. 16-18
-
-
Ladanyi, M.1
Cha, C.2
Lewis, R.3
Jhanwar, S.C.4
Huvos, A.G.5
Healey, J.H.6
-
6
-
-
0026649648
-
The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
-
Momand, J., Zambetti, G. P., Olson, D. C., George, D., and Levine, A. J. The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation. Cell, 69: 1237-1245, 1992.
-
(1992)
Cell
, vol.69
, pp. 1237-1245
-
-
Momand, J.1
Zambetti, G.P.2
Olson, D.C.3
George, D.4
Levine, A.J.5
-
7
-
-
0027325132
-
Oncoprotein MDM2 conceals the activation domain of tumor suppressor p53
-
Oliner, J. D., Pietenpol, J. A., Thiagalingam, S., Gyuris, J., Kinzler, K. W., and Vogelstein, B. Oncoprotein MDM2 conceals the activation domain of tumor suppressor p53. Nature (Lond.), 362: 857-860, 1993.
-
(1993)
Nature (Lond.)
, vol.362
, pp. 857-860
-
-
Oliner, J.D.1
Pietenpol, J.A.2
Thiagalingam, S.3
Gyuris, J.4
Kinzler, K.W.5
Vogelstein, B.6
-
8
-
-
0027222956
-
Mapping of the p53 and mdm-2 interaction domains
-
Chen, J., Marechal, V., and Levine, A. J. Mapping of the p53 and mdm-2 interaction domains. Mol. Cell. Biol., 13: 4107-4114, 1993.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 4107-4114
-
-
Chen, J.1
Marechal, V.2
Levine, A.J.3
-
9
-
-
0027498314
-
The mdm-2 oncogene can overcome wild-type p53 suppression of transformed cell growth
-
Finlay, C. A. The mdm-2 oncogene can overcome wild-type p53 suppression of transformed cell growth. Mol. Cell. Biol., 13: 301-306, 1993.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 301-306
-
-
Finlay, C.A.1
-
10
-
-
0028303752
-
Several hydrophobic amino acids in the p53 amino-termmal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 EIB 55- 54 6D protein
-
Lin, J., Chen, J., Elenbaas, B., and Levine, A. J. Several hydrophobic amino acids in the p53 amino-termmal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 EIB 55- 54 6D protein. Genes Dev., 8: 1235-1246, 1994.
-
(1994)
Genes Dev.
, vol.8
, pp. 1235-1246
-
-
Lin, J.1
Chen, J.2
Elenbaas, B.3
Levine, A.J.4
-
11
-
-
0030905284
-
Mdm2 promotes the rapid degradation of p53
-
Haupt, Y., Maya, R., Kazaz, A., and Oren, M. Mdm2 promotes the rapid degradation of p53. Nature (Lond.), 387: 296-299, 1997.
-
(1997)
Nature (Lond.)
, vol.387
, pp. 296-299
-
-
Haupt, Y.1
Maya, R.2
Kazaz, A.3
Oren, M.4
-
12
-
-
0029985647
-
Cell type-specific inhibition of p53-mediated apoptosis by mdm2
-
Haupt, Y., Barak, Y., and Oren, M. Cell type-specific inhibition of p53-mediated apoptosis by mdm2. EMBO J., 15: 1596-1606, 1996.
-
(1996)
EMBO J.
, vol.15
, pp. 1596-1606
-
-
Haupt, Y.1
Barak, Y.2
Oren, M.3
-
13
-
-
0028823020
-
Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53
-
Montes de Oca Luna, R., Wagner, D. S., and Lozano, G. Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53. Nature (Lond.), 378: 203-206, 1995.
-
(1995)
Nature (Lond.)
, vol.378
, pp. 203-206
-
-
Montes De Oca Luna, R.1
Wagner, D.S.2
Lozano, G.3
-
14
-
-
0028834902
-
Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53
-
Jones, S. N., Roe, A. E., Donehower, L. A., and Bradley, A. Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53. Nature (Lond.), 378: 206-208, 1995.
-
(1995)
Nature (Lond.)
, vol.378
, pp. 206-208
-
-
Jones, S.N.1
Roe, A.E.2
Donehower, L.A.3
Bradley, A.4
-
15
-
-
0028568315
-
Cell cycle control and cancer
-
Washington DC
-
Hartwell, L. H., and Kastan, M. B. Cell cycle control and cancer. Science (Washington DC), 266: 1821-1828, 1994.
-
(1994)
Science
, vol.266
, pp. 1821-1828
-
-
Hartwell, L.H.1
Kastan, M.B.2
-
16
-
-
0032549704
-
The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53
-
Pomerantz, J., Schreiber-Agus, N., Liegeois, N. J., Silverman, A., Alland, L., Chin, L., Potes, J., Chen, K., Orlow, I., Lee, H. W., Cordon-Cardo, C., DePinho RA. The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53. Cell, 92: 713-723 1998.
-
(1998)
Cell
, vol.92
, pp. 713-723
-
-
Pomerantz, J.1
Schreiber-Agus, N.2
Liegeois, N.J.3
Silverman, A.4
Alland, L.5
Chin, L.6
Potes, J.7
Chen, K.8
Orlow, I.9
Lee, H.W.10
Cordon-Cardo, C.11
DePinho, R.A.12
-
18
-
-
14444281159
-
Targeted expression of MDM2 uncouples S phase from mitosis and inhibits mammary gland development independent of p53
-
Lundgren, K., Montes de Oca Luna, R., McNeill, Y. B., Emerick, E. P., Spencer, B., Barfield, C. R., Lozano, G., Rosenberg, M. P., Finlay, C. A. Targeted expression of MDM2 uncouples S phase from mitosis and inhibits mammary gland development independent of p53. Genes Dev., 11: 714-725, 1997.
-
(1997)
Genes Dev.
, vol.11
, pp. 714-725
-
-
Lundgren, K.1
Montes De Oca Luna, R.2
McNeill, Y.B.3
Emerick, E.P.4
Spencer, B.5
Barfield, C.R.6
Lozano, G.7
Rosenberg, M.P.8
Finlay, C.A.9
-
19
-
-
0032989098
-
Overproduction of MDM2 in vivo disrupts S phase independent of E2F1
-
Reinke, V., Bortner, D. M., Ameise, L. L., Lundgren, K., Rosenberg, M. P., Finlay, C. A., and Lozano, G. Overproduction of MDM2 in vivo disrupts S phase independent of E2F1. Cell Growth Differ., 10: 147-154, 1999.
-
(1999)
Cell Growth Differ.
, vol.10
, pp. 147-154
-
-
Reinke, V.1
Bortner, D.M.2
Ameise, L.L.3
Lundgren, K.4
Rosenberg, M.P.5
Finlay, C.A.6
Lozano, G.7
-
20
-
-
0029028354
-
Interaction between the retinoblastoma protein and the oncoprotein MDM2
-
Xiao, Z. X., Chen, J., Levine, A. J., Modjtahedl, N., Xing, J., Sellers, W. R., and Livingston, D. M. Interaction between the retinoblastoma protein and the oncoprotein MDM2. Nature (Lond.), 575: 694-698, 1995.
-
(1995)
Nature (Lond.)
, vol.575
, pp. 694-698
-
-
Xiao, Z.X.1
Chen, J.2
Levine, A.J.3
Modjtahedl, N.4
Xing, J.5
Sellers, W.R.6
Livingston, D.M.7
-
21
-
-
0032146274
-
The regulation of E2F by pRB-family proteins
-
Dyson, N. The regulation of E2F by pRB-family proteins. Genes Dev., 12: 2245-2262, 1998.
-
(1998)
Genes Dev.
, vol.12
, pp. 2245-2262
-
-
Dyson, N.1
-
22
-
-
0029028353
-
Stipulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein
-
Martin, K., Trouche, D., Hagemeier, C., Srensen, T. S., LaThangue, N. B., and Kouzarides, T. Stipulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein. Nature (Lond.), 375: 691-694, 1995.
-
(1995)
Nature (Lond.)
, vol.375
, pp. 691-694
-
-
Martin, K.1
Trouche, D.2
Hagemeier, C.3
Srensen, T.S.4
LaThangue, N.B.5
Kouzarides, T.6
-
23
-
-
0028360766
-
Overexpression of E2F-1 in rat embryo fibroblasts leads to neoplastic transformation
-
Singh, P., Wong, S. H., and Hong, W. Overexpression of E2F-1 in rat embryo fibroblasts leads to neoplastic transformation. EMBO J., 13: 3329-3338, 1994.
-
(1994)
EMBO J.
, vol.13
, pp. 3329-3338
-
-
Singh, P.1
Wong, S.H.2
Hong, W.3
-
24
-
-
0028577731
-
Oncogenic capacity of the E2F1 gene
-
Johnson, D. G., Cress, W. D., Jakoi, L., and Nevins, J. R. Oncogenic capacity of the E2F1 gene. Proc. Natl. Acad. Sci. USA, 91: 12823-12827, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 12823-12827
-
-
Johnson, D.G.1
Cress, W.D.2
Jakoi, L.3
Nevins, J.R.4
-
25
-
-
0028945789
-
Multiple members of the E2F transcription factor family are the products of oncogenes
-
Xu, G., Livingston, D. M., and Krek, W. Multiple members of the E2F transcription factor family are the products of oncogenes. Proc. Natl. Acad. Sci. USA, 92: 1357-1361, 1995.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 1357-1361
-
-
Xu, G.1
Livingston, D.M.2
Krek, W.3
-
26
-
-
0031886093
-
Regulation of cell proliferation by the E2F transcription factors
-
Helin, K. Regulation of cell proliferation by the E2F transcription factors. Curr. Opin. Genet. Dev., 8: 28-35, 1998.
-
(1998)
Curr. Opin. Genet. Dev.
, vol.8
, pp. 28-35
-
-
Helin, K.1
-
27
-
-
0027491775
-
Expression of transcription factor E2F1 induces quiescent cells to enter S phase
-
Johnson, D. G., Schwarz, J. K., Cress, W. D., and Nevins, J. R. Expression of transcription factor E2F1 induces quiescent cells to enter S phase. Nature (Lond.), 365: 349-352, 1993.
-
(1993)
Nature (Lond.)
, vol.365
, pp. 349-352
-
-
Johnson, D.G.1
Schwarz, J.K.2
Cress, W.D.3
Nevins, J.R.4
-
28
-
-
0028960617
-
E2F1 Overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis
-
Kowalik, T. F., DeGregori, J., Schwarz, J. K., and Nevins, J. R. E2F1 Overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis. J. Virol., 69: 2491-2500, 1995.
-
(1995)
J. Virol.
, vol.69
, pp. 2491-2500
-
-
Kowalik, T.F.1
DeGregori, J.2
Schwarz, J.K.3
Nevins, J.R.4
-
29
-
-
0032510342
-
Deregulated expression of E2F1 induces hyperplasia and cooperates with ras in skin tumor development
-
Pierce, A. M., Fisher, S. M., Conti, C. J., and Johnson, D. G. Deregulated expression of E2F1 induces hyperplasia and cooperates with ras in skin tumor development. Oncogene, 16: 1267-1276, 1998.
-
(1998)
Oncogene
, vol.16
, pp. 1267-1276
-
-
Pierce, A.M.1
Fisher, S.M.2
Conti, C.J.3
Johnson, D.G.4
-
30
-
-
0032537851
-
E2F-1-induced p53-independent apoptosis in transgenic mice
-
Holmberg, C., Helin, K., Sehested, M., and Karlstrom, O. E2F-1-induced p53-independent apoptosis in transgenic mice. Oncogene, 17: 143-155, 1998.
-
(1998)
Oncogene
, vol.17
, pp. 143-155
-
-
Holmberg, C.1
Helin, K.2
Sehested, M.3
Karlstrom, O.4
-
31
-
-
0029888359
-
Tumor induction and tissue atrophy in mice lacking E2F-1
-
Yamasaki, L., Jacks, T., Bronson, R., Goillot, E., Harlow, E., and Dyson, N. J. Tumor induction and tissue atrophy in mice lacking E2F-1. Cell, 85: 537-548, 1996.
-
(1996)
Cell
, vol.85
, pp. 537-548
-
-
Yamasaki, L.1
Jacks, T.2
Bronson, R.3
Goillot, E.4
Harlow, E.5
Dyson, N.J.6
-
32
-
-
0029949784
-
E2F-1 functions in mice to promote apoptosis and suppress proliferation
-
Field, S. J., Tsai, F. Y., Kou, F., Zubiaga, A. M., Kaelin, W. G., Livingston, D. M., Orkin, S. H., and Greenberg, M. E. E2F-1 functions in mice to promote apoptosis and suppress proliferation. Cell, 85: 549-561, 1996.
-
(1996)
Cell
, vol.85
, pp. 549-561
-
-
Field, S.J.1
Tsai, F.Y.2
Kou, F.3
Zubiaga, A.M.4
Kaelin, W.G.5
Livingston, D.M.6
Orkin, S.H.7
Greenberg, M.E.8
-
33
-
-
0032160407
-
Key roles for E2F1 in signaling p53-dependent apoptosis and in cell division within developing tumors
-
Pan, H., Yin, C., Dyson, N. J., Harlow, E., Yamasaki, L., and Van Dyke, T. Key roles for E2F1 in signaling p53-dependent apoptosis and in cell division within developing tumors. Mol. Cell, 2: 283-292, 1998.
-
(1998)
Mol. Cell
, vol.2
, pp. 283-292
-
-
Pan, H.1
Yin, C.2
Dyson, N.J.3
Harlow, E.4
Yamasaki, L.5
Van Dyke, T.6
-
34
-
-
0031897273
-
Loss of E2F-1 reduces tumorigenesis and extends the lifespan of Rb1(+/-) mice
-
Yamasaki, L., Bronson, R., Williams, B. O., Dyson, N. J., Harlow, E., and Jacks, T. Loss of E2F-1 reduces tumorigenesis and extends the lifespan of Rb1(+/-) mice. Nat. Genet., 18: 360-364, 1998.
-
(1998)
Nat. Genet.
, vol.18
, pp. 360-364
-
-
Yamasaki, L.1
Bronson, R.2
Williams, B.O.3
Dyson, N.J.4
Harlow, E.5
Jacks, T.6
-
35
-
-
0028222124
-
p53, and E2F-1 cooperate to mediate apoptosis
-
Wu, X. W., and Levine, A. J. p53, and E2F-1 cooperate to mediate apoptosis. Proc. Natl. Acad. Sci. USA, 91: 3602-3606, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 3602-3606
-
-
Wu, X.W.1
Levine, A.J.2
-
36
-
-
0028061670
-
Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis
-
Shan, B., and Lee, W. H. Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis. Mol. Cell. Biol., 14: 8166-8173, 1994.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 8166-8173
-
-
Shan, B.1
Lee, W.H.2
-
37
-
-
0027947383
-
Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis
-
Qin, X. Q., Livingston, D. M., Kaelin, W. G., Jr., and Adams, P. D. Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis. Proc. Natl. Acad. Sci. USA, 91: 10918-10922, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 10918-10922
-
-
Qin, X.Q.1
Livingston, D.M.2
Kaelin Jr., W.G.3
Adams, P.D.4
-
38
-
-
0030739355
-
Induction of DNA synthesis and apoptosis are separable functions of E2F-1
-
Phillips, A. C., Bates, S., Ryan, K. M., Helin, K., and Vousden, K. H. Induction of DNA synthesis and apoptosis are separable functions of E2F-1. Genes Dev., 11: 1853-1863, 1997.
-
(1997)
Genes Dev.
, vol.11
, pp. 1853-1863
-
-
Phillips, A.C.1
Bates, S.2
Ryan, K.M.3
Helin, K.4
Vousden, K.H.5
-
39
-
-
0030850752
-
E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction
-
Hsieh, J. K., Fredersdorf, S., Kouzarides, T., Martin, K., and Lu, X. E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction. Genes Dev., 11: 1840-1852 1997.
-
(1997)
Genes Dev.
, vol.11
, pp. 1840-1852
-
-
Hsieh, J.K.1
Fredersdorf, S.2
Kouzarides, T.3
Martin, K.4
Lu, X.5
-
40
-
-
0031024991
-
E2F-1 cooperates with topoisomerase II inhibition and DNA damage to selectively augment p53-independent apoptosis
-
Nip, J., Strom, D. K., Fee, B. E., Zambetti, G., Cleveland, J., and Hiebert, S. W. E2F-1 cooperates with topoisomerase II inhibition and DNA damage to selectively augment p53-independent apoptosis. Mol. Cell. Biol., 17: 1049-1056, 1997.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 1049-1056
-
-
Nip, J.1
Strom, D.K.2
Fee, B.E.3
Zambetti, G.4
Cleveland, J.5
Hiebert, S.W.6
-
41
-
-
0031930154
-
Bypass of abnormal MDM2 inhibition of p53-dependent growth suppression
-
Meng, R. D., Shih, H., Prabhu, N. S., George, D. L., and el-Deiry, W. S. Bypass of abnormal MDM2 inhibition of p53-dependent growth suppression. Clin. Cancer Res., 4: 251-259, 1998.
-
(1998)
Clin. Cancer Res.
, vol.4
, pp. 251-259
-
-
Meng, R.D.1
Shih, H.2
Prabhu, N.S.3
George, D.L.4
El-Deiry, W.S.5
-
42
-
-
0030813584
-
Adenovirus-mediated overexpression of the transcription factor E2F-1 induces apoptosis in human breast and ovarian carcinoma cell lines and does not require p53
-
Hunt, K. K., Deng, J., Liu, T. J., Wilson-Heiner, M., Swisher, S. G., Clayman, G. L., and Hung, M. C. Adenovirus-mediated overexpression of the transcription factor E2F-1 induces apoptosis in human breast and ovarian carcinoma cell lines and does not require p53. Cancer Res., 57: 4722-4726, 1997.
-
(1997)
Cancer Res.
, vol.57
, pp. 4722-4726
-
-
Hunt, K.K.1
Deng, J.2
Liu, T.J.3
Wilson-Heiner, M.4
Swisher, S.G.5
Clayman, G.L.6
Hung, M.C.7
-
43
-
-
0031749470
-
Overexpression of E2F-1 in glioma triggers apoptosis and suppresses tumor growth in vitro and in vivo
-
Fueyo, J., Gomez-Manzano, C., Yung, W. K., Liu, T. J., Alemany, R., McDonnell, T. J., Shi, X., Rao, J. S., Levin, V. A., and Kyritsis, A. P. Overexpression of E2F-1 in glioma triggers apoptosis and suppresses tumor growth in vitro and in vivo. Nat. Med., 4: 685-690, 1998.
-
(1998)
Nat. Med.
, vol.4
, pp. 685-690
-
-
Fueyo, J.1
Gomez-Manzano, C.2
Yung, W.K.3
Liu, T.J.4
Alemany, R.5
McDonnell, T.J.6
Shi, X.7
Rao, J.S.8
Levin, V.A.9
Kyritsis, A.P.10
-
44
-
-
0031670757
-
Combination E2F-1 and p53 gene transfer does not enhance growth inhibition in human squamous cell carcinoma of the head and neck
-
Frank, D. K., Liu, T. J., Frederick, M. J., and Clayman, G. L. Combination E2F-1 and p53 gene transfer does not enhance growth inhibition in human squamous cell carcinoma of the head and neck. Clin. Cancer Res., 4: 2265-2272, 1998.
-
(1998)
Clin. Cancer Res.
, vol.4
, pp. 2265-2272
-
-
Frank, D.K.1
Liu, T.J.2
Frederick, M.J.3
Clayman, G.L.4
-
45
-
-
0032608285
-
Gene therapy for gliomas: p53 and E2F-1 proteins and the target of apoptosis
-
Gomez-Manzano, C., Fueyo, J., Alameda, F., Kyritsis, A. P., and Yung, W. K. Gene therapy for gliomas: p53 and E2F-1 proteins and the target of apoptosis. Int. J. Mol. Med., 3: 81-85, 1999.
-
(1999)
Int. J. Mol. Med.
, vol.3
, pp. 81-85
-
-
Gomez-Manzano, C.1
Fueyo, J.2
Alameda, F.3
Kyritsis, A.P.4
Yung, W.K.5
-
46
-
-
0031992159
-
E2F-1-specific induction of apoptosis and p53 accumulation, which is blocked by Mdm2
-
Kowalik, T. F., DeGregori, J., Leone, G., Jakoi, L., and Nevins, J. R. E2F-1-specific induction of apoptosis and p53 accumulation, which is blocked by Mdm2. Cell Growth Differ., 9: 113-118, 1998.
-
(1998)
Cell Growth Differ.
, vol.9
, pp. 113-118
-
-
Kowalik, T.F.1
DeGregori, J.2
Leone, G.3
Jakoi, L.4
Nevins, J.R.5
-
47
-
-
0026740449
-
Amplification of a gene encoding a p53-associated protein in human sarcomas
-
Oliner, J. D., Kinzler, K. W., Meltzer, P. S., George, D., and Vogelstein, B. Amplification of a gene encoding a p53-associated protein in human sarcomas [see comments]. Nature (Lond.), 358: 80-83, 1992.
-
(1992)
Nature (Lond.)
, vol.358
, pp. 80-83
-
-
Oliner, J.D.1
Kinzler, K.W.2
Meltzer, P.S.3
George, D.4
Vogelstein, B.5
-
48
-
-
0025853776
-
Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumor cell line
-
Fakharzadeh, S. S., Trusko, S. P., and George, D. Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumor cell line. EMBO J., 10: 1565-1569, 1991.
-
(1991)
EMBO J.
, vol.10
, pp. 1565-1569
-
-
Fakharzadeh, S.S.1
Trusko, S.P.2
George, D.3
-
49
-
-
0028148752
-
Percutaneous transluminal in vivo gene transfer by recombinant adenovirus in normal porcine coronary arteries, atherosclerotic arteries, and two models of coronary restenosis
-
French, B. A., Mazur, W., Ali, N. M., Geske, R. S., Finnigan, J. P., and Rodgers, G. P. Percutaneous transluminal in vivo gene transfer by recombinant adenovirus in normal porcine coronary arteries, atherosclerotic arteries, and two models of coronary restenosis. Circulation, 90: 2402-2413, 1994.
-
(1994)
Circulation
, vol.90
, pp. 2402-2413
-
-
French, B.A.1
Mazur, W.2
Ali, N.M.3
Geske, R.S.4
Finnigan, J.P.5
Rodgers, G.P.6
-
50
-
-
0002025785
-
Manipulation of adenovirus vectors
-
E. J. Murray (ed.), Clifton, NJ: The Humana Press, Inc.
-
Graham, F. L., and Prevec, L. Manipulation of adenovirus vectors. In: E. J. Murray (ed.), Gene Transfer and Expression Protocols, Methods in Molecular Biology, Vol. 7, pp. 109-128. Clifton, NJ: The Humana Press, Inc., 1991.
-
(1991)
Gene Transfer and Expression Protocols, Methods in Molecular Biology
, vol.7
, pp. 109-128
-
-
Graham, F.L.1
Prevec, L.2
-
52
-
-
0027941355
-
Concentration-dependent differences in the mechanisms by which caffeine potentiates etoposide cytotoxicity in HeLa cells
-
Lock, R. B., Galperina, O. V., Feldhoff, R. C., and Rhodes, L. J. Concentration-dependent differences in the mechanisms by which caffeine potentiates etoposide cytotoxicity in HeLa cells. Cancer Res., 54: 4933-4939, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 4933-4939
-
-
Lock, R.B.1
Galperina, O.V.2
Feldhoff, R.C.3
Rhodes, L.J.4
-
53
-
-
0032031063
-
Protease activation and cleavage of poly(ADP-ribose) polymerase: An integral part of apoptosis in response to photodynamic treatment
-
He, J., Whitacre, C. M., Xue, L. Y., Berger, N. A., and Oleinick, N. L. Protease activation and cleavage of poly(ADP-ribose) polymerase: an integral part of apoptosis in response to photodynamic treatment. Cancer Res., 58: 940-946, 1998.
-
(1998)
Cancer Res.
, vol.58
, pp. 940-946
-
-
He, J.1
Whitacre, C.M.2
Xue, L.Y.3
Berger, N.A.4
Oleinick, N.L.5
-
54
-
-
0026648674
-
Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
-
Gavriell, Y., Sherman, Y., and Ben-Sasson, S. A. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol., 3: 493-501, 1992.
-
(1992)
J. Cell Biol.
, vol.3
, pp. 493-501
-
-
Gavriell, Y.1
Sherman, Y.2
Ben-Sasson, S.A.3
-
55
-
-
0028860556
-
E2F-1:DP-1 induces p53 and overrides survival factors to trigger apoptosis
-
Hiebert, S. W., Packham, G., Strom, D. K., Haffner, R., Oren, M., and Zambetti, G. E2F-1:DP-1 induces p53 and overrides survival factors to trigger apoptosis. Mol. Cell. Biol., 15: 6864-6874, 1995.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 6864-6874
-
-
Hiebert, S.W.1
Packham, G.2
Strom, D.K.3
Haffner, R.4
Oren, M.5
Zambetti, G.6
-
56
-
-
0033583313
-
Caspase-dependent activation of calpain during drug-induced apoptosis
-
Wood, D. E., and Newcomb, E. W. Caspase-dependent activation of calpain during drug-induced apoptosis. J. Biol. Chem., 274: 8309-8315, 1999.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 8309-8315
-
-
Wood, D.E.1
Newcomb, E.W.2
-
57
-
-
0032480260
-
Bax cleavage is mediated by calpain during drug-induced apoptosis
-
Wood, D. E., Thomas, A., Devi, L. A., Berman Y., Beavis, R. C., Reed, J. C., and Newcomb, E. W. Bax cleavage is mediated by calpain during drug-induced apoptosis. Oncogene, 17: 1069-1078, 1998.
-
(1998)
Oncogene
, vol.17
, pp. 1069-1078
-
-
Wood, D.E.1
Thomas, A.2
Devi, L.A.3
Berman, Y.4
Beavis, R.C.5
Reed, J.C.6
Newcomb, E.W.7
-
58
-
-
0030957746
-
Identification of the MDM2 oncoprotein as a substrate for CPP32-like apoptotic proteases
-
Erhardt, P., Tomaselli, K. J., and Cooper, G. M. Identification of the MDM2 oncoprotein as a substrate for CPP32-like apoptotic proteases. J. Biol. Chem., 272: 15049-15052,1997.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 15049-15052
-
-
Erhardt, P.1
Tomaselli, K.J.2
Cooper, G.M.3
-
59
-
-
0030955170
-
Proteolytic cleavage of the mdm2 oncoprotein during apoptosis
-
Chen, L., Marechal, V., Moreau, J., Levine, A. J., and Chen, J. Proteolytic cleavage of the mdm2 oncoprotein during apoptosis. J. Biol. Chem., 272: 22966-22973, 1997.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 22966-22973
-
-
Chen, L.1
Marechal, V.2
Moreau, J.3
Levine, A.J.4
Chen, J.5
-
60
-
-
0032548105
-
A 60 kd MDM2 isoform is produced by caspase cleavage in non-apoptotic tumor cells
-
Pochampally, R., Fodera, B., Chen, L., Shao, W., Levine, E. A., Chen, J. A 60 kd MDM2 isoform is produced by caspase cleavage in non-apoptotic tumor cells. Oncogene, 17: 2629-2636 1998.
-
(1998)
Oncogene
, vol.17
, pp. 2629-2636
-
-
Pochampally, R.1
Fodera, B.2
Chen, L.3
Shao, W.4
Levine, E.A.5
Chen, J.6
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