메뉴 건너뛰기




Volumn 586, Issue 18, 2012, Pages 2981-2989

E-cadherin dysfunction in gastric cancer - Cellular consequences, clinical applications and open questions

Author keywords

Adhesion; E cadherin; Gastric cancer; HDGC; Invasion; Signalling; Tumour

Indexed keywords

HISTONE DEACETYLASE INHIBITOR; UVOMORULIN;

EID: 84864922992     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2012.07.045     Document Type: Conference Paper
Times cited : (71)

References (147)
  • 1
    • 73949150127 scopus 로고    scopus 로고
    • Nature meets nurture: Molecular genetics of gastric cancer
    • 10.1007/s00439-009-0722-x
    • A.N. Milne, F. Carneiro, C. O'Morain, and G.J. Offerhaus Nature meets nurture: molecular genetics of gastric cancer Hum. Genet. 126 2009 615 628 10.1007/s00439-009-0722-x
    • (2009) Hum. Genet. , vol.126 , pp. 615-628
    • Milne, A.N.1    Carneiro, F.2    O'Morain, C.3    Offerhaus, G.J.4
  • 2
    • 12644292106 scopus 로고
    • The Two Histological Main Types of Gastric Carcinoma: Diffuse and So-Called Intestinal-Type Carcinoma. An Attempt at a Histo-Clinical Classification
    • P. Lauren The Two Histological Main Types of Gastric Carcinoma: Diffuse and So-Called Intestinal-Type Carcinoma. An Attempt at a Histo-Clinical Classification Acta. Pathol. Microbiol. Scand. 64 1965 31 49
    • (1965) Acta. Pathol. Microbiol. Scand. , vol.64 , pp. 31-49
    • Lauren, P.1
  • 3
    • 84861089134 scopus 로고    scopus 로고
    • Genetic aspects of gastric cancer instability
    • 10.1100/2012/761909
    • P. Hudler Genetic aspects of gastric cancer instability ScientificWorldJournal 2012 2012 761909 10.1100/2012/761909
    • (2012) ScientificWorldJournal , vol.2012 , pp. 761909
    • Hudler, P.1
  • 4
    • 32344433111 scopus 로고    scopus 로고
    • Genetics, pathology, and clinics of familial gastric cancer
    • C. Oliveira, R. Seruca, and F. Carneiro Genetics, pathology, and clinics of familial gastric cancer Int. J. Surg. Pathol. 14 2006 21 33
    • (2006) Int. J. Surg. Pathol. , vol.14 , pp. 21-33
    • Oliveira, C.1    Seruca, R.2    Carneiro, F.3
  • 5
    • 19644385515 scopus 로고    scopus 로고
    • Gastric cancer: New genetic developments
    • 10.1002/jso.20214 discussion 133
    • H.T. Lynch, W. Grady, G. Suriano, and D. Huntsman Gastric cancer: New genetic developments J Surg. Oncol. 90 2005 114 133 10.1002/jso.20214 discussion 133
    • (2005) J Surg. Oncol. , vol.90 , pp. 114-133
    • Lynch, H.T.1    Grady, W.2    Suriano, G.3    Huntsman, D.4
  • 6
    • 0028641478 scopus 로고
    • Glycosylation features of gastric carcinoma initiation and progression. A review with emphasis on simple mucin-type carbohydrates and histo-blood group antigens of the Lewis system
    • F. Carneiro, M. Amado, L. David, H. Clausen, and M. Sobrinho-Simoes Glycosylation features of gastric carcinoma initiation and progression. A review with emphasis on simple mucin-type carbohydrates and histo-blood group antigens of the Lewis system Eur. J. Cancer Prev. 3 Suppl 2 1994 39 46
    • (1994) Eur. J. Cancer Prev. , vol.3 , Issue.SUPPL. 2 , pp. 39-46
    • Carneiro, F.1    Amado, M.2    David, L.3    Clausen, H.4    Sobrinho-Simoes, M.5
  • 7
    • 3142631886 scopus 로고    scopus 로고
    • Molecular basis of gastric cancer development and progression
    • 10.1007/s10120-004-0277-4
    • L. Zheng, L. Wang, J. Ajani, and K. Xie Molecular basis of gastric cancer development and progression Gastric Cancer 7 2004 61 77 10.1007/s10120-004- 0277-4
    • (2004) Gastric Cancer , vol.7 , pp. 61-77
    • Zheng, L.1    Wang, L.2    Ajani, J.3    Xie, K.4
  • 10
    • 36048984754 scopus 로고    scopus 로고
    • After Helicobacter pylori, genetic susceptibility to gastric carcinoma revisited
    • 10.1111/j.1523-5378.2007.00564.x
    • P. Canedo, C. Figueiredo, and J.C. Machado After Helicobacter pylori, genetic susceptibility to gastric carcinoma revisited Helicobacter 12 Suppl 2 2007 45 49 10.1111/j.1523-5378.2007.00564.x
    • (2007) Helicobacter , vol.12 , Issue.SUPPL. 2 , pp. 45-49
    • Canedo, P.1    Figueiredo, C.2    MacHado, J.C.3
  • 11
    • 78650904591 scopus 로고    scopus 로고
    • Salt intake and gastric cancer risk according to Helicobacter pylori infection, smoking, tumour site and histological type
    • 10.1038/sj.bjc.6605993
    • B. Peleteiro, C. Lopes, C. Figueiredo, and N. Lunet Salt intake and gastric cancer risk according to Helicobacter pylori infection, smoking, tumour site and histological type Br. J. Cancer 104 2011 198 207 10.1038/sj.bjc.6605993
    • (2011) Br. J. Cancer , vol.104 , pp. 198-207
    • Peleteiro, B.1    Lopes, C.2    Figueiredo, C.3    Lunet, N.4
  • 14
    • 0038581169 scopus 로고    scopus 로고
    • Changing neighbours, changing behaviour: Cell adhesion molecule-mediated signalling during tumour progression
    • 10.1093/emboj/cdg228
    • G. Christofori Changing neighbours, changing behaviour: cell adhesion molecule-mediated signalling during tumour progression Embo J. 22 2003 2318 2323 10.1093/emboj/cdg228
    • (2003) Embo J. , vol.22 , pp. 2318-2323
    • Christofori, G.1
  • 15
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • 10.1016/j.cell.2011.02.013
    • D. Hanahan, and R.A. Weinberg Hallmarks of cancer: the next generation Curr. Opin. Cell Biol. 144 2011 646 674 10.1016/j.cell.2011.02.013
    • (2011) Curr. Opin. Cell Biol. , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 16
    • 70450198396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and disease
    • 10.1016/j.cell.2009.11.007
    • J.P. Thiery, H. Acloque, R.Y. Huang, and M.A. Nieto Epithelial- mesenchymal transitions in development and disease Curr. Opin. Cell Biol. 139 2009 871 890 10.1016/j.cell.2009.11.007
    • (2009) Curr. Opin. Cell Biol. , vol.139 , pp. 871-890
    • Thiery, J.P.1    Acloque, H.2    Huang, R.Y.3    Nieto, M.A.4
  • 17
    • 77953118628 scopus 로고    scopus 로고
    • Snail1 links transcriptional control with epigenetic regulation
    • 10.1038/emboj.2010.92
    • G. Christofori Snail1 links transcriptional control with epigenetic regulation Embo J. 29 2010 1787 1789 10.1038/emboj.2010.92
    • (2010) Embo J. , vol.29 , pp. 1787-1789
    • Christofori, G.1
  • 18
    • 84862535544 scopus 로고    scopus 로고
    • Dishonorable Discharge: The Oncogenic Roles of Cleaved E-Cadherin Fragments
    • 10.1158/0008-5472.CAN-11-3498
    • J.M. David, and A.K. Rajasekaran Dishonorable Discharge: The Oncogenic Roles of Cleaved E-Cadherin Fragments Adv. Cancer Res. 2012 10.1158/0008-5472. CAN-11-3498
    • (2012) Adv. Cancer Res.
    • David, J.M.1    Rajasekaran, A.K.2
  • 19
    • 57349114162 scopus 로고    scopus 로고
    • The cell-cell adhesion molecule E-cadherin
    • 10.1007/s00018-008-8281-1
    • F. van Roy, and G. Berx The cell-cell adhesion molecule E-cadherin Cell Mol. Life Sci. 65 2008 3756 3788 10.1007/s00018-008-8281-1
    • (2008) Cell Mol. Life Sci. , vol.65 , pp. 3756-3788
    • Van Roy, F.1    Berx, G.2
  • 20
    • 47549099616 scopus 로고    scopus 로고
    • Cadherins in development and cancer
    • 10.1039/b719215k
    • M.P. Stemmler Cadherins in development and cancer Mol. Biosyst. 4 2008 835 850 10.1039/b719215k
    • (2008) Mol. Biosyst. , vol.4 , pp. 835-850
    • Stemmler, M.P.1
  • 21
    • 0017758251 scopus 로고
    • Functional correlation between cell adhesive properties and some cell surface proteins
    • M. Takeichi Functional correlation between cell adhesive properties and some cell surface proteins J. Cell. Biol. 75 1977 464 474
    • (1977) J. Cell. Biol. , vol.75 , pp. 464-474
    • Takeichi, M.1
  • 22
    • 0027980534 scopus 로고
    • The genes for the calcium-dependent cell adhesion molecules P- and E-cadherin are tandemly arranged in the human genome
    • M.J. Bussemakers, A. van Bokhoven, M. Voller, F.P. Smit, and J.A. Schalken The genes for the calcium-dependent cell adhesion molecules P- and E-cadherin are tandemly arranged in the human genome Biochem. Biophys. Res. Commun. 203 1994 1291 1294
    • (1994) Biochem. Biophys. Res. Commun. , vol.203 , pp. 1291-1294
    • Bussemakers, M.J.1    Van Bokhoven, A.2    Voller, M.3    Smit, F.P.4    Schalken, J.A.5
  • 24
    • 0029160437 scopus 로고
    • Morphogenetic roles of classic cadherins
    • M. Takeichi Morphogenetic roles of classic cadherins Curr. Opin. Cell Biol. 7 1995 619 627
    • (1995) Curr. Opin. Cell Biol. , vol.7 , pp. 619-627
    • Takeichi, M.1
  • 26
    • 0033119626 scopus 로고    scopus 로고
    • A new crystal structure, Ca2+ dependence and mutational analysis reveal molecular details of E-cadherin homoassociation
    • 10.1093/emboj/18.7.1738
    • O. Pertz, D. Bozic, A.W. Koch, C. Fauser, A. Brancaccio, and J. Engel A new crystal structure, Ca2+ dependence and mutational analysis reveal molecular details of E-cadherin homoassociation Embo J. 18 1999 1738 1747 10.1093/emboj/18.7.1738
    • (1999) Embo J. , vol.18 , pp. 1738-1747
    • Pertz, O.1    Bozic, D.2    Koch, A.W.3    Fauser, C.4    Brancaccio, A.5    Engel, J.6
  • 27
    • 23144442645 scopus 로고    scopus 로고
    • Regulation of cadherin-mediated adhesion in morphogenesis
    • 10.1038/nrm1699
    • B.M. Gumbiner Regulation of cadherin-mediated adhesion in morphogenesis Nat. Rev. Mol. Cell Biol. 6 2005 622 634 10.1038/nrm1699
    • (2005) Nat. Rev. Mol. Cell Biol. , vol.6 , pp. 622-634
    • Gumbiner, B.M.1
  • 28
    • 0025374899 scopus 로고
    • Uvomorulin-catenin complex formation is regulated by a specific domain in the cytoplasmic region of the cell adhesion molecule
    • M. Ozawa, M. Ringwald, and R. Kemler Uvomorulin-catenin complex formation is regulated by a specific domain in the cytoplasmic region of the cell adhesion molecule Proc. Natl. Acad. Sci. USA 87 1990 4246 4250
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 4246-4250
    • Ozawa, M.1    Ringwald, M.2    Kemler, R.3
  • 29
    • 0025325167 scopus 로고
    • Cadherins: A molecular family important in selective cell-cell adhesion
    • 10.1146/annurev.bi.59.070190.001321
    • M. Takeichi Cadherins: a molecular family important in selective cell-cell adhesion Annu. Rev. Biochem. 59 1990 237 252 10.1146/annurev.bi.59. 070190.001321
    • (1990) Annu. Rev. Biochem. , vol.59 , pp. 237-252
    • Takeichi, M.1
  • 30
    • 0027723788 scopus 로고
    • Catenins as mediators of the cytoplasmic functions of cadherins
    • B.M. Gumbiner, and P.D. McCrea Catenins as mediators of the cytoplasmic functions of cadherins J. Cell Sci. Suppl. 17 1993 155 158
    • (1993) J. Cell Sci. Suppl. , vol.17 , pp. 155-158
    • Gumbiner, B.M.1    McCrea, P.D.2
  • 31
    • 0032482201 scopus 로고    scopus 로고
    • The juxtamembrane region of the cadherin cytoplasmic tail supports lateral clustering, adhesive strengthening, and interaction with p120ctn
    • A.S. Yap, C.M. Niessen, and B.M. Gumbiner The juxtamembrane region of the cadherin cytoplasmic tail supports lateral clustering, adhesive strengthening, and interaction with p120ctn J. Cell. Biol. 141 1998 779 789
    • (1998) J. Cell. Biol. , vol.141 , pp. 779-789
    • Yap, A.S.1    Niessen, C.M.2    Gumbiner, B.M.3
  • 33
    • 69549130809 scopus 로고    scopus 로고
    • Remodeling of the adherens junctions during morphogenesis
    • 10.1016/S0070-2153(09)89002-9
    • T. Nishimura, and M. Takeichi Remodeling of the adherens junctions during morphogenesis Curr. Top. Dev. Biol. 89 2009 33 54 10.1016/S0070-2153(09)89002-9
    • (2009) Curr. Top. Dev. Biol. , vol.89 , pp. 33-54
    • Nishimura, T.1    Takeichi, M.2
  • 34
    • 0018945602 scopus 로고
    • A cell surface glycoprotein involved in the compaction of embryonal carcinoma cells and cleavage stage embryos
    • F. Hyafil, D. Morello, C. Babinet, and F. Jacob A cell surface glycoprotein involved in the compaction of embryonal carcinoma cells and cleavage stage embryos Curr. Opin. Cell Biol. 21 1980 927 934
    • (1980) Curr. Opin. Cell Biol. , vol.21 , pp. 927-934
    • Hyafil, F.1    Morello, D.2    Babinet, C.3    Jacob, F.4
  • 35
    • 0023926935 scopus 로고
    • The cadherins: Cell-cell adhesion molecules controlling animal morphogenesis
    • M. Takeichi The cadherins: cell-cell adhesion molecules controlling animal morphogenesis Development 102 1988 639 655
    • (1988) Development , vol.102 , pp. 639-655
    • Takeichi, M.1
  • 36
    • 0027077584 scopus 로고
    • Epithelial differentiation and intercellular junction formation in the mouse early embryo
    • Fleming TP, Javed Q & Hay M (1992) Epithelial differentiation and intercellular junction formation in the mouse early embryo. Development, 105-112.
    • (1992) Development , pp. 105-112
    • Fleming, T.P.1    Javed, Q.2    Hay, M.3
  • 37
    • 0022895355 scopus 로고
    • A novel cadherin cell adhesion molecule: Its expression patterns associated with implantation and organogenesis of mouse embryos
    • A. Nose, and M. Takeichi A novel cadherin cell adhesion molecule: its expression patterns associated with implantation and organogenesis of mouse embryos J. Cell Biol. 103 1986 2649 2658
    • (1986) J. Cell Biol. , vol.103 , pp. 2649-2658
    • Nose, A.1    Takeichi, M.2
  • 38
    • 62249185259 scopus 로고    scopus 로고
    • Adhesion molecules in human trophoblast - A review
    • 10.1016/j.placenta.2008.12.001
    • J.D. Aplin, C.J. Jones, and L.K. Harris Adhesion molecules in human trophoblast - a review I. Villous trophoblast. Placenta 30 2009 293 298 10.1016/j.placenta.2008.12.001
    • (2009) I. Villous Trophoblast. Placenta , vol.30 , pp. 293-298
    • Aplin, J.D.1    Jones, C.J.2    Harris, L.K.3
  • 39
    • 0028059290 scopus 로고
    • E-cadherin null mutant embryos fail to form a trophectoderm epithelium
    • L. Larue, M. Ohsugi, J. Hirchenhain, and R. Kemler E-cadherin null mutant embryos fail to form a trophectoderm epithelium Proc. Natl. Acad. Sci. USA 91 1994 8263 8267
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 8263-8267
    • Larue, L.1    Ohsugi, M.2    Hirchenhain, J.3    Kemler, R.4
  • 41
    • 33845414010 scopus 로고    scopus 로고
    • Cadherins in development: Cell adhesion, sorting, and tissue morphogenesis
    • 10.1101/gad.1486806
    • J.M. Halbleib, and W.J. Nelson Cadherins in development: cell adhesion, sorting, and tissue morphogenesis Genes Dev. 20 2006 3199 3214 10.1101/gad.1486806
    • (2006) Genes Dev. , vol.20 , pp. 3199-3214
    • Halbleib, J.M.1    Nelson, W.J.2
  • 43
    • 0033789680 scopus 로고    scopus 로고
    • The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells
    • 10.1038/35000034
    • E. Batlle, E. Sancho, C. Franci, D. Dominguez, M. Monfar, J. Baulida, and A. Garcia De Herreros The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells Nat. Cell Biol. 2 2000 84 89 10.1038/35000034
    • (2000) Nat. Cell Biol. , vol.2 , pp. 84-89
    • Batlle, E.1    Sancho, E.2    Franci, C.3    Dominguez, D.4    Monfar, M.5    Baulida, J.6    Garcia De Herreros, A.7
  • 44
    • 0345599013 scopus 로고    scopus 로고
    • Autoregulation of E-cadherin expression by cadherin-cadherin interactions: The roles of beta-catenin signaling, Slug, and MAPK
    • 10.1083/jcb.200308162
    • M. Conacci-Sorrell, I. Simcha, T. Ben-Yedidia, J. Blechman, P. Savagner, and A. Ben-Ze'ev Autoregulation of E-cadherin expression by cadherin-cadherin interactions: the roles of beta-catenin signaling, Slug, and MAPK J. Cell. Biol. 163 2003 847 857 10.1083/jcb.200308162
    • (2003) J. Cell. Biol. , vol.163 , pp. 847-857
    • Conacci-Sorrell, M.1    Simcha, I.2    Ben-Yedidia, T.3    Blechman, J.4    Savagner, P.5    Ben-Ze'Ev, A.6
  • 46
    • 34249289041 scopus 로고    scopus 로고
    • Snail, Zeb and bHLH factors in tumour progression: An alliance against the epithelial phenotype?
    • 10.1038/nrc2131
    • H. Peinado, D. Olmeda, and A. Cano Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? Nat. Rev. Cancer 7 2007 415 428 10.1038/nrc2131
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 415-428
    • Peinado, H.1    Olmeda, D.2    Cano, A.3
  • 48
    • 0036392129 scopus 로고    scopus 로고
    • Epigenetic versus genetic alterations in the inactivation of E-cadherin
    • G. Strathdee Epigenetic versus genetic alterations in the inactivation of E-cadherin Semin. Cancer Biol. 12 2002 373 379
    • (2002) Semin. Cancer Biol. , vol.12 , pp. 373-379
    • Strathdee, G.1
  • 49
  • 52
    • 0033593803 scopus 로고    scopus 로고
    • Coupling assembly of the E-cadherin/beta-catenin complex to efficient endoplasmic reticulum exit and basal-lateral membrane targeting of E-cadherin in polarized MDCK cells
    • Y.T. Chen, D.B. Stewart, and W.J. Nelson Coupling assembly of the E-cadherin/beta-catenin complex to efficient endoplasmic reticulum exit and basal-lateral membrane targeting of E-cadherin in polarized MDCK cells J. Cell. Biol. 144 1999 687 699
    • (1999) J. Cell. Biol. , vol.144 , pp. 687-699
    • Chen, Y.T.1    Stewart, D.B.2    Nelson, W.J.3
  • 53
    • 0034681430 scopus 로고    scopus 로고
    • Casein kinase II phosphorylation of E-cadherin increases E-cadherin/beta-catenin interaction and strengthens cell-cell adhesion
    • H. Lickert, A. Bauer, R. Kemler, and J. Stappert Casein kinase II phosphorylation of E-cadherin increases E-cadherin/beta-catenin interaction and strengthens cell-cell adhesion J. Biol. Chem. 275 2000 5090 5095
    • (2000) J. Biol. Chem. , vol.275 , pp. 5090-5095
    • Lickert, H.1    Bauer, A.2    Kemler, R.3    Stappert, J.4
  • 54
    • 4143146438 scopus 로고    scopus 로고
    • The ins and outs of E-cadherin trafficking
    • 10.1016/j.tcb.2004.07.007
    • D.M. Bryant, and J.L. Stow The ins and outs of E-cadherin trafficking Trends Cell Biol. 14 2004 427 434 10.1016/j.tcb.2004.07.007
    • (2004) Trends Cell Biol. , vol.14 , pp. 427-434
    • Bryant, D.M.1    Stow, J.L.2
  • 55
    • 24644447079 scopus 로고    scopus 로고
    • The regulation of cadherin-mediated adhesion by tyrosine phosphorylation/dephosphorylation of beta-catenin
    • 10.1016/j.ceb.2005.08.009
    • J. Lilien, and J. Balsamo The regulation of cadherin-mediated adhesion by tyrosine phosphorylation/dephosphorylation of beta-catenin Curr. Opin. Cell Biol. 17 2005 459 465 10.1016/j.ceb.2005.08.009
    • (2005) Curr. Opin. Cell Biol. , vol.17 , pp. 459-465
    • Lilien, J.1    Balsamo, J.2
  • 56
    • 0035805117 scopus 로고    scopus 로고
    • The structure of the beta-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by beta-catenin
    • A.H. Huber, and W.I. Weis The structure of the beta-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by beta-catenin Curr. Opin. Cell Biol. 105 2001 391 402
    • (2001) Curr. Opin. Cell Biol. , vol.105 , pp. 391-402
    • Huber, A.H.1    Weis, W.I.2
  • 57
    • 0035503219 scopus 로고    scopus 로고
    • Cytoplasmic O-glycosylation prevents cell surface transport of E-cadherin during apoptosis
    • 10.1093/emboj/20.21.5999
    • W. Zhu, B. Leber, and D.W. Andrews Cytoplasmic O-glycosylation prevents cell surface transport of E-cadherin during apoptosis Embo J. 20 2001 5999 6007 10.1093/emboj/20.21.5999
    • (2001) Embo J. , vol.20 , pp. 5999-6007
    • Zhu, W.1    Leber, B.2    Andrews, D.W.3
  • 59
    • 33747377812 scopus 로고    scopus 로고
    • N-glycosylation affects the molecular organization and stability of E-cadherin junctions
    • 10.1074/jbc.M512621200
    • A. Liwosz, T. Lei, and M.A. Kukuruzinska N-glycosylation affects the molecular organization and stability of E-cadherin junctions J. Biol. Chem. 281 2006 23138 23149 10.1074/jbc.M512621200
    • (2006) J. Biol. Chem. , vol.281 , pp. 23138-23149
    • Liwosz, A.1    Lei, T.2    Kukuruzinska, M.A.3
  • 60
    • 0035801516 scopus 로고    scopus 로고
    • An essential role for ARF6-regulated membrane traffic in adherens junction turnover and epithelial cell migration
    • 10.1093/emboj/20.17.4973
    • F. Palacios, L. Price, J. Schweitzer, J.G. Collard, and C. D'Souza-Schorey An essential role for ARF6-regulated membrane traffic in adherens junction turnover and epithelial cell migration Embo J. 20 2001 4973 4986 10.1093/emboj/20.17.4973
    • (2001) Embo J. , vol.20 , pp. 4973-4986
    • Palacios, F.1    Price, L.2    Schweitzer, J.3    Collard, J.G.4    D'Souza-Schorey, C.5
  • 61
    • 80051508756 scopus 로고    scopus 로고
    • ADP-ribosylation factor 6 mediates E-cadherin recovery by chemical chaperones
    • 10.1371/journal.pone.0023188
    • J. Figueiredo, J. Simoes-Correia, O. Soderberg, G. Suriano, and R. Seruca ADP-ribosylation factor 6 mediates E-cadherin recovery by chemical chaperones PLoS One 6 2011 e23188 10.1371/journal.pone.0023188
    • (2011) PLoS One , vol.6 , pp. 23188
    • Figueiredo, J.1    Simoes-Correia, J.2    Soderberg, O.3    Suriano, G.4    Seruca, R.5
  • 63
    • 41949117520 scopus 로고    scopus 로고
    • Cdc42 regulates E-cadherin ubiquitination and degradation through an epidermal growth factor receptor to Src-mediated pathway
    • 10.1074/jbc.M703300200
    • Y. Shen, D.S. Hirsch, C.A. Sasiela, and W.J. Wu Cdc42 regulates E-cadherin ubiquitination and degradation through an epidermal growth factor receptor to Src-mediated pathway J. Biol. Chem. 283 2008 5127 5137 10.1074/jbc.M703300200
    • (2008) J. Biol. Chem. , vol.283 , pp. 5127-5137
    • Shen, Y.1    Hirsch, D.S.2    Sasiela, C.A.3    Wu, W.J.4
  • 64
    • 11144296871 scopus 로고    scopus 로고
    • Lysosomal targeting of E-cadherin: A unique mechanism for the down-regulation of cell-cell adhesion during epithelial to mesenchymal transitions
    • 10.1128/MCB.25.1.389-402.2005
    • F. Palacios, J.S. Tushir, Y. Fujita, and C. D'Souza-Schorey Lysosomal targeting of E-cadherin: a unique mechanism for the down-regulation of cell-cell adhesion during epithelial to mesenchymal transitions Nat. Rev. Mol. Cell Biol. 25 2005 389 402 10.1128/MCB.25.1.389-402.2005
    • (2005) Nat. Rev. Mol. Cell Biol. , vol.25 , pp. 389-402
    • Palacios, F.1    Tushir, J.S.2    Fujita, Y.3    D'Souza-Schorey, C.4
  • 65
    • 0242708621 scopus 로고    scopus 로고
    • A core function for p120-catenin in cadherin turnover
    • 10.1083/jcb.200307111
    • M.A. Davis, R.C. Ireton, and A.B. Reynolds A core function for p120-catenin in cadherin turnover J. Cell. Biol. 163 2003 525 534 10.1083/jcb.200307111
    • (2003) J. Cell. Biol. , vol.163 , pp. 525-534
    • Davis, M.A.1    Ireton, R.C.2    Reynolds, A.B.3
  • 66
    • 77953879928 scopus 로고    scopus 로고
    • Involvement of members of the cadherin superfamily in cancer
    • 10.1101/cshperspect.a003129
    • G. Berx, and F. van Roy Involvement of members of the cadherin superfamily in cancer Cold Spring Harb. Perspect Biol. 1 2009 a003129 10.1101/cshperspect.a003129
    • (2009) Cold Spring Harb. Perspect Biol. , vol.1 , pp. 003129
    • Berx, G.1    Van Roy, F.2
  • 68
    • 84859113973 scopus 로고    scopus 로고
    • E-cadherin's dark side: Possible role in tumor progression
    • 10.1016/j.bbcan.2012.03.002
    • F.J. Rodriguez, L.J. Lewis-Tuffin, and P.Z. Anastasiadis E-cadherin's dark side: Possible role in tumor progression Biochim. Biophys. Acta 1826 2012 23 31 10.1016/j.bbcan.2012.03.002
    • (2012) Biochim. Biophys. Acta , vol.1826 , pp. 23-31
    • Rodriguez, F.J.1    Lewis-Tuffin, L.J.2    Anastasiadis, P.Z.3
  • 69
    • 77952902430 scopus 로고    scopus 로고
    • Mechanisms of motility in metastasizing cells
    • 10.1158/1541-7786.MCR-10-0139
    • M. Yilmaz, and G. Christofori Mechanisms of motility in metastasizing cells Mol. Cancer Res. 8 2010 629 642 10.1158/1541-7786.MCR-10-0139
    • (2010) Mol. Cancer Res. , vol.8 , pp. 629-642
    • Yilmaz, M.1    Christofori, G.2
  • 70
    • 0028245813 scopus 로고
    • Cadherin expression in carcinomas: Role in the formation of cell junctions and the prevention of invasiveness
    • W. Birchmeier, and J. Behrens Cadherin expression in carcinomas: role in the formation of cell junctions and the prevention of invasiveness Biochim. Biophys. Acta 1198 1994 11 26
    • (1994) Biochim. Biophys. Acta , vol.1198 , pp. 11-26
    • Birchmeier, W.1    Behrens, J.2
  • 71
    • 0033079605 scopus 로고    scopus 로고
    • The role of the cell-adhesion molecule E-cadherin as a tumour-suppressor gene
    • G. Christofori, and H. Semb The role of the cell-adhesion molecule E-cadherin as a tumour-suppressor gene Trends Biochem. Sci. 24 1999 73 76
    • (1999) Trends Biochem. Sci. , vol.24 , pp. 73-76
    • Christofori, G.1    Semb, H.2
  • 72
    • 77954673384 scopus 로고    scopus 로고
    • Hereditary diffuse gastric cancer: Translation of CDH1 germline mutations into clinical practice
    • 10.1007/s10120-009-0531-x
    • P. Guilford, B. Humar, and V. Blair Hereditary diffuse gastric cancer: translation of CDH1 germline mutations into clinical practice Gastric Cancer 13 2010 1 10 10.1007/s10120-009-0531-x
    • (2010) Gastric Cancer , vol.13 , pp. 1-10
    • Guilford, P.1    Humar, B.2    Blair, V.3
  • 75
    • 62449154651 scopus 로고    scopus 로고
    • E-cadherin deficiency initiates gastric signet-ring cell carcinoma in mice and man
    • 10.1158/0008-5472.CAN-08-2457
    • B. Humar, V. Blair, A. Charlton, H. More, I. Martin, and P. Guilford E-cadherin deficiency initiates gastric signet-ring cell carcinoma in mice and man Adv. Cancer Res. 69 2009 2050 2056 10.1158/0008-5472.CAN-08-2457
    • (2009) Adv. Cancer Res. , vol.69 , pp. 2050-2056
    • Humar, B.1    Blair, V.2    Charlton, A.3    More, H.4    Martin, I.5    Guilford, P.6
  • 76
    • 77955856687 scopus 로고    scopus 로고
    • Pathology and genetics of familial gastric cancer
    • 10.1177/1066896910366463
    • F. Carneiro, C. Oliveira, and R. Seruca Pathology and genetics of familial gastric cancer Int. J. Surg. Pathol. 18 2010 33S 36S 10.1177/1066896910366463
    • (2010) Int. J. Surg. Pathol. , vol.18
    • Carneiro, F.1    Oliveira, C.2    Seruca, R.3
  • 79
    • 0029951738 scopus 로고    scopus 로고
    • E-cadherin is inactivated in a majority of invasive human lobular breast cancers by truncation mutations throughout its extracellular domain
    • G. Berx, A.M. Cleton-Jansen, K. Strumane, W.J. de Leeuw, F. Nollet, F. van Roy, and C. Cornelisse E-cadherin is inactivated in a majority of invasive human lobular breast cancers by truncation mutations throughout its extracellular domain Oncogene 13 1996 1919 1925
    • (1996) Oncogene , vol.13 , pp. 1919-1925
    • Berx, G.1    Cleton-Jansen, A.M.2    Strumane, K.3    De Leeuw, W.J.4    Nollet, F.5    Van Roy, F.6    Cornelisse, C.7
  • 84
    • 84855422195 scopus 로고    scopus 로고
    • Frequency of CDH1 germline mutations in gastric carcinoma coming from high- and low-risk areas: Metanalysis and systematic review of the literature
    • 10.1186/1471-2407-12-8
    • G. Corso, D. Marrelli, V. Pascale, C. Vindigni, and F. Roviello Frequency of CDH1 germline mutations in gastric carcinoma coming from high- and low-risk areas: metanalysis and systematic review of the literature Br. J. Cancer 12 2012 8 10.1186/1471-2407-12-8
    • (2012) Br. J. Cancer , vol.12 , pp. 8
    • Corso, G.1    Marrelli, D.2    Pascale, V.3    Vindigni, C.4    Roviello, F.5
  • 87
    • 34249989159 scopus 로고    scopus 로고
    • Founder and recurrent CDH1 mutations in families with hereditary diffuse gastric cancer
    • 10.1001/jama.297.21.2360
    • P. Kaurah, A. MacMillan, N. Boyd, J. Senz, A. De Luca, N. Chun, G. Suriano, S. Zaor, L. Van Manen, and C. Gilpin Founder and recurrent CDH1 mutations in families with hereditary diffuse gastric cancer JAMA 297 2007 2360 2372 10.1001/jama.297.21.2360
    • (2007) JAMA , vol.297 , pp. 2360-2372
    • Kaurah, P.1    MacMillan, A.2    Boyd, N.3    Senz, J.4    De Luca, A.5    Chun, N.6    Suriano, G.7    Zaor, S.8    Van Manen, L.9    Gilpin, C.10
  • 90
    • 10744230392 scopus 로고    scopus 로고
    • E-cadherin germline missense mutations and cell phenotype: Evidence for the independence of cell invasion on the motile capabilities of the cells
    • 10.1093/hmg/ddg316
    • G. Suriano, M.J. Oliveira, D. Huntsman, A.R. Mateus, P. Ferreira, F. Casares, C. Oliveira, F. Carneiro, J.C. Machado, and M. Mareel E-cadherin germline missense mutations and cell phenotype: evidence for the independence of cell invasion on the motile capabilities of the cells Hum. Mol. Genet. 12 2003 3007 3016 10.1093/hmg/ddg316
    • (2003) Hum. Mol. Genet. , vol.12 , pp. 3007-3016
    • Suriano, G.1    Oliveira, M.J.2    Huntsman, D.3    Mateus, A.R.4    Ferreira, P.5    Casares, F.6    Oliveira, C.7    Carneiro, F.8    MacHado, J.C.9    Mareel, M.10
  • 91
    • 34249980933 scopus 로고    scopus 로고
    • A model to infer the pathogenic significance of CDH1 germline missense variants
    • 10.1007/s00109-006-0091-z
    • G. Suriano, S. Seixas, J. Rocha, and R. Seruca A model to infer the pathogenic significance of CDH1 germline missense variants Acta. Pathol. Microbiol. Scand. 84 2006 1023 1031 10.1007/s00109-006-0091-z
    • (2006) Acta. Pathol. Microbiol. Scand. , vol.84 , pp. 1023-1031
    • Suriano, G.1    Seixas, S.2    Rocha, J.3    Seruca, R.4
  • 92
    • 84858685771 scopus 로고    scopus 로고
    • E-cadherin destabilization accounts for the pathogenicity of missense mutations in hereditary diffuse gastric cancer
    • 10.1371/journal.pone.0033783
    • J. Simoes-Correia, J. Figueiredo, R. Lopes, F. Stricher, C. Oliveira, L. Serrano, and R. Seruca E-cadherin destabilization accounts for the pathogenicity of missense mutations in hereditary diffuse gastric cancer PLoS One 7 2012 e33783 10.1371/journal.pone.0033783
    • (2012) PLoS One , vol.7 , pp. 33783
    • Simoes-Correia, J.1    Figueiredo, J.2    Lopes, R.3    Stricher, F.4    Oliveira, C.5    Serrano, L.6    Seruca, R.7
  • 93
    • 84864924716 scopus 로고    scopus 로고
    • The importance of E-cadherin binding partners to evaluate the pathogenicity of E-cadherin missense mutations associated to HDGC
    • in press
    • Figueiredo J, Söderberg O, Simões-Correia J, Grannas K, Suriano G & Seruca R The importance of E-cadherin binding partners to evaluate the pathogenicity of E-cadherin missense mutations associated to HDGC. Eur. J. Hum Genetics in press.
    • Eur. J. Hum Genetics
    • Figueiredo J, S.1
  • 100
    • 3042767202 scopus 로고    scopus 로고
    • MicroRNAs: Small RNAs with a big role in gene regulation
    • 10.1038/nrg1379
    • L. He, and G.J. Hannon MicroRNAs: small RNAs with a big role in gene regulation Nat. Rev. Genet. 5 2004 522 531 10.1038/nrg1379
    • (2004) Nat. Rev. Genet. , vol.5 , pp. 522-531
    • He, L.1    Hannon, G.J.2
  • 101
    • 47249091921 scopus 로고    scopus 로고
    • The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2
    • 10.1074/jbc.C800074200
    • M. Korpal, E.S. Lee, G. Hu, and Y. Kang The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2 J. Biol. Chem. 283 2008 14910 14914 10.1074/jbc.C800074200
    • (2008) J. Biol. Chem. , vol.283 , pp. 14910-14914
    • Korpal, M.1    Lee, E.S.2    Hu, G.3    Kang, Y.4
  • 102
    • 41649091906 scopus 로고    scopus 로고
    • The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
    • 10.1101/gad.1640608
    • S.M. Park, A.B. Gaur, E. Lengyel, and M.E. Peter The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2 Genes Dev. 22 2008 894 907 10.1101/gad.1640608
    • (2008) Genes Dev. , vol.22 , pp. 894-907
    • Park, S.M.1    Gaur, A.B.2    Lengyel, E.3    Peter, M.E.4
  • 104
    • 54949124637 scopus 로고    scopus 로고
    • Endoplasmic reticulum quality control: A new mechanism of E-cadherin regulation and its implication in cancer
    • 10.1093/hmg/ddn249
    • J. Simoes-Correia, J. Figueiredo, C. Oliveira, J. van Hengel, R. Seruca, F. van Roy, and G. Suriano Endoplasmic reticulum quality control: a new mechanism of E-cadherin regulation and its implication in cancer Hum. Mol. Genet. 17 2008 3566 3576 10.1093/hmg/ddn249
    • (2008) Hum. Mol. Genet. , vol.17 , pp. 3566-3576
    • Simoes-Correia, J.1    Figueiredo, J.2    Oliveira, C.3    Van Hengel, J.4    Seruca, R.5    Van Roy, F.6    Suriano, G.7
  • 110
    • 79951963618 scopus 로고    scopus 로고
    • Adhesion molecule signalling: Not always a sticky business
    • 10.1038/nrm3068
    • U. Cavallaro, and E. Dejana Adhesion molecule signalling: not always a sticky business Nat. Rev. Mol. Cell Biol. 12 2011 189 197 10.1038/nrm3068
    • (2011) Nat. Rev. Mol. Cell Biol. , vol.12 , pp. 189-197
    • Cavallaro, U.1    Dejana, E.2
  • 111
    • 1542347695 scopus 로고    scopus 로고
    • Convergence of Wnt, beta-catenin, and cadherin pathways
    • 10.1126/science.1094291
    • W.J. Nelson, and R. Nusse Convergence of Wnt, beta-catenin, and cadherin pathways Science 303 2004 1483 1487 10.1126/science.1094291
    • (2004) Science , vol.303 , pp. 1483-1487
    • Nelson, W.J.1    Nusse, R.2
  • 112
    • 0042337360 scopus 로고    scopus 로고
    • The intracellular E-cadherin germline mutation V832 M lacks the ability to mediate cell-cell adhesion and to suppress invasion
    • 10.1038/sj.onc.1206672
    • G. Suriano, D. Mulholland, O. de Wever, P. Ferreira, A.R. Mateus, E. Bruyneel, C.C. Nelson, M.M. Mareel, J. Yokota, and D. Huntsman The intracellular E-cadherin germline mutation V832 M lacks the ability to mediate cell-cell adhesion and to suppress invasion Oncogene 22 2003 5716 5719 10.1038/sj.onc.1206672
    • (2003) Oncogene , vol.22 , pp. 5716-5719
    • Suriano, G.1    Mulholland, D.2    De Wever, O.3    Ferreira, P.4    Mateus, A.R.5    Bruyneel, E.6    Nelson, C.C.7    Mareel, M.M.8    Yokota, J.9    Huntsman, D.10
  • 113
    • 1242317791 scopus 로고    scopus 로고
    • Expression of seven main Rho family members in gastric carcinoma
    • 10.1016/j.bbrc.2004.01.108
    • Y. Pan, F. Bi, N. Liu, Y. Xue, X. Yao, Y. Zheng, and D. Fan Expression of seven main Rho family members in gastric carcinoma Biochem. Biophys. Res. Commun. 315 2004 686 691 10.1016/j.bbrc.2004.01.108
    • (2004) Biochem. Biophys. Res. Commun. , vol.315 , pp. 686-691
    • Pan, Y.1    Bi, F.2    Liu, N.3    Xue, Y.4    Yao, X.5    Zheng, Y.6    Fan, D.7
  • 117
    • 78449254848 scopus 로고    scopus 로고
    • Clinicopathological significance of E-cadherin, VEGF, and MMPs in gastric cancer
    • 10.1007/s13277-010-0068-y
    • Y. Zhou, G. Li, J. Wu, Z. Zhang, Z. Wu, P. Fan, T. Hao, X. Zhang, M. Li, and F. Zhang Clinicopathological significance of E-cadherin, VEGF, and MMPs in gastric cancer Tumour Biol. 31 2010 549 558 10.1007/s13277-010-0068-y
    • (2010) Tumour Biol. , vol.31 , pp. 549-558
    • Zhou, Y.1    Li, G.2    Wu, J.3    Zhang, Z.4    Wu, Z.5    Fan, P.6    Hao, T.7    Zhang, X.8    Li, M.9    Zhang, F.10
  • 118
    • 28044453504 scopus 로고    scopus 로고
    • DNA ploidy analysis and expression of MMP-9, TIMP-2, and E-cadherin in gastric carcinoma
    • J.F. Zhang, Y.P. Zhang, F.Y. Hao, C.X. Zhang, Y.J. Li, and X.R. Ji DNA ploidy analysis and expression of MMP-9, TIMP-2, and E-cadherin in gastric carcinoma World J. Gastroenterol. 11 2005 5592 5600
    • (2005) World J. Gastroenterol. , vol.11 , pp. 5592-5600
    • Zhang, J.F.1    Zhang, Y.P.2    Hao, F.Y.3    Zhang, C.X.4    Li, Y.J.5    Ji, X.R.6
  • 122
    • 0037537477 scopus 로고    scopus 로고
    • Promoter methylation of E-cadherin gene in gastric mucosa associated with Helicobacter pylori infection and in gastric cancer
    • A.O. Chan, S.K. Lam, B.C. Wong, W.M. Wong, M.F. Yuen, Y.H. Yeung, W.M. Hui, A. Rashid, and Y.L. Kwong Promoter methylation of E-cadherin gene in gastric mucosa associated with Helicobacter pylori infection and in gastric cancer Gut 52 2003 502 506
    • (2003) Gut , vol.52 , pp. 502-506
    • Chan, A.O.1    Lam, S.K.2    Wong, B.C.3    Wong, W.M.4    Yuen, M.F.5    Yeung, Y.H.6    Hui, W.M.7    Rashid, A.8    Kwong, Y.L.9
  • 123
    • 84867332710 scopus 로고    scopus 로고
    • Helicobacter pylori induces promoter methylation of E-cadherin via interleukin-1beta activation of nitric oxide production in gastric cancer cells
    • 10.1002/cncr.27519
    • F.Y. Huang, A.O. Chan, A. Rashid, D.K. Wong, C.H. Cho, and M.F. Yuen Helicobacter pylori induces promoter methylation of E-cadherin via interleukin-1beta activation of nitric oxide production in gastric cancer cells Adv. Cancer Res. 2012 10.1002/cncr.27519
    • (2012) Adv. Cancer Res.
    • Huang, F.Y.1    Chan, A.O.2    Rashid, A.3    Wong, D.K.4    Cho, C.H.5    Yuen, M.F.6
  • 124
    • 70449532978 scopus 로고    scopus 로고
    • Ectodomain shedding of E-cadherin and c-Met is induced by Helicobacter pylori infection
    • 10.1016/j.yexcr.2009.07.029
    • W. Schirrmeister, T. Gnad, T. Wex, S. Higashiyama, C. Wolke, M. Naumann, and U. Lendeckel Ectodomain shedding of E-cadherin and c-Met is induced by Helicobacter pylori infection Exp. Cell Res. 315 2009 3500 3508 10.1016/j.yexcr.2009.07.029
    • (2009) Exp. Cell Res. , vol.315 , pp. 3500-3508
    • Schirrmeister, W.1    Gnad, T.2    Wex, T.3    Higashiyama, S.4    Wolke, C.5    Naumann, M.6    Lendeckel, U.7
  • 125
    • 77957232471 scopus 로고    scopus 로고
    • Helicobacter pylori HtrA is a new secreted virulence factor that cleaves E-cadherin to disrupt intercellular adhesion
    • 10.1038/embor.2010.114
    • B. Hoy, M. Lower, C. Weydig, G. Carra, N. Tegtmeyer, T. Geppert, P. Schroder, N. Sewald, S. Backert, and G. Schneider Helicobacter pylori HtrA is a new secreted virulence factor that cleaves E-cadherin to disrupt intercellular adhesion EMBO Rep. 11 2010 798 804 10.1038/embor.2010.114
    • (2010) EMBO Rep. , vol.11 , pp. 798-804
    • Hoy, B.1    Lower, M.2    Weydig, C.3    Carra, G.4    Tegtmeyer, N.5    Geppert, T.6    Schroder, P.7    Sewald, N.8    Backert, S.9    Schneider, G.10
  • 126
    • 4544313059 scopus 로고    scopus 로고
    • Helicobacter pylori infection targets adherens junction regulatory proteins and results in increased rates of migration in human gastric epithelial cells
    • 10.1128/IAI.72.9.5181-5192.2004
    • V.S. Conlin, S.B. Curtis, Y. Zhao, E.D. Moore, V.C. Smith, R.M. Meloche, B.B. Finlay, and A.M. Buchan Helicobacter pylori infection targets adherens junction regulatory proteins and results in increased rates of migration in human gastric epithelial cells Infect. Immun. 72 2004 5181 5192 10.1128/IAI.72.9.5181-5192.2004
    • (2004) Infect. Immun. , vol.72 , pp. 5181-5192
    • Conlin, V.S.1    Curtis, S.B.2    Zhao, Y.3    Moore, E.D.4    Smith, V.C.5    Meloche, R.M.6    Finlay, B.B.7    Buchan, A.M.8
  • 127
    • 27744471043 scopus 로고    scopus 로고
    • Interaction of CagA with Crk plays an important role in Helicobacter pylori-induced loss of gastric epithelial cell adhesion
    • 10.1084/jem.20051027
    • M. Suzuki, H. Mimuro, T. Suzuki, M. Park, T. Yamamoto, and C. Sasakawa Interaction of CagA with Crk plays an important role in Helicobacter pylori-induced loss of gastric epithelial cell adhesion J. Exp. Med. 202 2005 1235 1247 10.1084/jem.20051027
    • (2005) J. Exp. Med. , vol.202 , pp. 1235-1247
    • Suzuki, M.1    Mimuro, H.2    Suzuki, T.3    Park, M.4    Yamamoto, T.5    Sasakawa, C.6
  • 129
    • 67649120160 scopus 로고    scopus 로고
    • CagA associates with c-Met, E-cadherin, and p120-catenin in a multiproteic complex that suppresses Helicobacter pylori-induced cell-invasive phenotype
    • 10.1086/604727
    • M.J. Oliveira, A.M. Costa, A.C. Costa, R.M. Ferreira, P. Sampaio, J.C. Machado, R. Seruca, M. Mareel, and C. Figueiredo CagA associates with c-Met, E-cadherin, and p120-catenin in a multiproteic complex that suppresses Helicobacter pylori-induced cell-invasive phenotype J. Infect. Dis. 200 2009 745 755 10.1086/604727
    • (2009) J. Infect. Dis. , vol.200 , pp. 745-755
    • Oliveira, M.J.1    Costa, A.M.2    Costa, A.C.3    Ferreira, R.M.4    Sampaio, P.5    MacHado, J.C.6    Seruca, R.7    Mareel, M.8    Figueiredo, C.9
  • 131
    • 79954726783 scopus 로고    scopus 로고
    • Loss of E-cadherin in mouse gastric epithelial cells induces signet ring-like cells, a possible precursor lesion of diffuse gastric cancer
    • 10.1111/j.1349-7006.2011.01890.x
    • A. Mimata, H. Fukamachi, Y. Eishi, and Y. Yuasa Loss of E-cadherin in mouse gastric epithelial cells induces signet ring-like cells, a possible precursor lesion of diffuse gastric cancer Cancer Sci. 102 2011 942 950 10.1111/j.1349-7006.2011.01890.x
    • (2011) Cancer Sci. , vol.102 , pp. 942-950
    • Mimata, A.1    Fukamachi, H.2    Eishi, Y.3    Yuasa, Y.4
  • 132
    • 84856574541 scopus 로고    scopus 로고
    • Clinical features of unresectable high-grade lung neuroendocrine carcinoma diagnosed using biopsy specimens
    • 10.1016/j.lungcan.2011.08.012
    • Y. Shimada, S. Niho, G. Ishii, T. Hishida, J. Yoshida, M. Nishimura, K. Yoh, K. Goto, H. Ohmatsu, and Y. Ohe Clinical features of unresectable high-grade lung neuroendocrine carcinoma diagnosed using biopsy specimens Lung Cancer 75 2012 368 373 10.1016/j.lungcan.2011.08.012
    • (2012) Lung Cancer , vol.75 , pp. 368-373
    • Shimada, Y.1    Niho, S.2    Ishii, G.3    Hishida, T.4    Yoshida, J.5    Nishimura, M.6    Yoh, K.7    Goto, K.8    Ohmatsu, H.9    Ohe, Y.10
  • 133
    • 54949124206 scopus 로고    scopus 로고
    • Establishment of an ovarian metastasis model and possible involvement of E-cadherin down-regulation in the metastasis
    • 10.1111/j.1349-7006.2008.00946.x
    • Y. Kuwabara, T. Yamada, K. Yamazaki, W.L. Du, K. Banno, D. Aoki, and M. Sakamoto Establishment of an ovarian metastasis model and possible involvement of E-cadherin down-regulation in the metastasis Cancer Sci. 99 2008 1933 1939 10.1111/j.1349-7006.2008.00946.x
    • (2008) Cancer Sci. , vol.99 , pp. 1933-1939
    • Kuwabara, Y.1    Yamada, T.2    Yamazaki, K.3    Du, W.L.4    Banno, K.5    Aoki, D.6    Sakamoto, M.7
  • 134
    • 33745184835 scopus 로고    scopus 로고
    • E-cadherin missense mutations, associated with hereditary diffuse gastric cancer (HDGC) syndrome, display distinct invasive behaviors and genetic interactions with the Wnt and Notch pathways in Drosophila epithelia
    • 10.1093/hmg/ddl093
    • P.S. Pereira, A. Teixeira, S. Pinho, P. Ferreira, J. Fernandes, C. Oliveira, R. Seruca, G. Suriano, and F. Casares E-cadherin missense mutations, associated with hereditary diffuse gastric cancer (HDGC) syndrome, display distinct invasive behaviors and genetic interactions with the Wnt and Notch pathways in Drosophila epithelia Hum. Mol. Genet. 15 2006 1704 1712 10.1093/hmg/ddl093
    • (2006) Hum. Mol. Genet. , vol.15 , pp. 1704-1712
    • Pereira, P.S.1    Teixeira, A.2    Pinho, S.3    Ferreira, P.4    Fernandes, J.5    Oliveira, C.6    Seruca, R.7    Suriano, G.8    Casares, F.9
  • 135
    • 73949154055 scopus 로고    scopus 로고
    • Using fruitflies to help understand the molecular mechanisms of human hereditary diffuse gastric cancer
    • 10.1387/ijdb.072277jc
    • J. Caldeira, P.S. Pereira, G. Suriano, and F. Casares Using fruitflies to help understand the molecular mechanisms of human hereditary diffuse gastric cancer Int. J. Dev. Biol. 53 2009 1557 1561 10.1387/ijdb.072277jc
    • (2009) Int. J. Dev. Biol. , vol.53 , pp. 1557-1561
    • Caldeira, J.1    Pereira, P.S.2    Suriano, G.3    Casares, F.4
  • 137
    • 0037477627 scopus 로고    scopus 로고
    • Adhesion-independent mechanism for suppression of tumor cell invasion by E-cadherin
    • 10.1083/jcb.200212033
    • A.S. Wong, and B.M. Gumbiner Adhesion-independent mechanism for suppression of tumor cell invasion by E-cadherin J. Cell. Biol. 161 2003 1191 1203 10.1083/jcb.200212033
    • (2003) J. Cell. Biol. , vol.161 , pp. 1191-1203
    • Wong, A.S.1    Gumbiner, B.M.2
  • 138
    • 33748997691 scopus 로고    scopus 로고
    • P120 catenin is essential for mesenchymal cadherin-mediated regulation of cell motility and invasiveness
    • 10.1083/jcb.200605022
    • M. Yanagisawa, and P.Z. Anastasiadis P120 catenin is essential for mesenchymal cadherin-mediated regulation of cell motility and invasiveness J. Cell. Biol. 174 2006 1087 1096 10.1083/jcb.200605022
    • (2006) J. Cell. Biol. , vol.174 , pp. 1087-1096
    • Yanagisawa, M.1    Anastasiadis, P.Z.2
  • 139
    • 0034800271 scopus 로고    scopus 로고
    • Hereditary diffuse gastric cancer
    • A. Dunbier, and P. Guilford Hereditary diffuse gastric cancer Adv. Cancer Res. 83 2001 55 65
    • (2001) Adv. Cancer Res. , vol.83 , pp. 55-65
    • Dunbier, A.1    Guilford, P.2
  • 140
    • 5444220519 scopus 로고    scopus 로고
    • Collective cell migration in morphogenesis and cancer
    • 10.1387/ijdb.041821
    • P. Friedl, Y. Hegerfeldt, and M. Tusch Collective cell migration in morphogenesis and cancer Int. J. Dev. Biol. 48 2004 441 449 10.1387/ijdb.041821
    • (2004) Int. J. Dev. Biol. , vol.48 , pp. 441-449
    • Friedl, P.1    Hegerfeldt, Y.2    Tusch, M.3
  • 141
    • 45749130288 scopus 로고    scopus 로고
    • Influence of age on soluble E-cadherin serum levels prevents its utility as a disease marker in gastric cancer patients
    • 10.1080/00365520802037370
    • C. Pedrazzani, S. Caruso, G. Corso, D. Marrelli, A. Neri, A. Berardi, and F. Roviello Influence of age on soluble E-cadherin serum levels prevents its utility as a disease marker in gastric cancer patients Scand. J. Gastroenterol. 43 2008 765 766 10.1080/00365520802037370
    • (2008) Scand. J. Gastroenterol. , vol.43 , pp. 765-766
    • Pedrazzani, C.1    Caruso, S.2    Corso, G.3    Marrelli, D.4    Neri, A.5    Berardi, A.6    Roviello, F.7
  • 142
    • 82255186386 scopus 로고    scopus 로고
    • Matrix metalloproteinases in tumorigenesis: An evolving paradigm
    • 10.1007/s00018-011-0763-x
    • H. Hua, M. Li, T. Luo, Y. Yin, and Y. Jiang Matrix metalloproteinases in tumorigenesis: an evolving paradigm Cell Mol. Life Sci. 68 2011 3853 3868 10.1007/s00018-011-0763-x
    • (2011) Cell Mol. Life Sci. , vol.68 , pp. 3853-3868
    • Hua, H.1    Li, M.2    Luo, T.3    Yin, Y.4    Jiang, Y.5
  • 143
    • 55449111278 scopus 로고    scopus 로고
    • Hereditary diffuse gastric cancer: Surgery, surveillance and unanswered questions
    • 10.2217/14796694.4.4.553
    • R.M. Cisco, and J.A. Norton Hereditary diffuse gastric cancer: surgery, surveillance and unanswered questions Future Oncol. 4 2008 553 559 10.2217/14796694.4.4.553
    • (2008) Future Oncol. , vol.4 , pp. 553-559
    • Cisco, R.M.1    Norton, J.A.2
  • 145
    • 84860589110 scopus 로고    scopus 로고
    • Selective DNA demethylation by fusion of TDG with a sequence-specific DNA-binding domain
    • 10.4161/epi.19509
    • D.J. Gregory, L. Mikhaylova, and A.V. Fedulov Selective DNA demethylation by fusion of TDG with a sequence-specific DNA-binding domain Epigenetics 7 2012 344 349 10.4161/epi.19509
    • (2012) Epigenetics , vol.7 , pp. 344-349
    • Gregory, D.J.1    Mikhaylova, L.2    Fedulov, A.V.3
  • 146
    • 36549010842 scopus 로고    scopus 로고
    • Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin
    • 10.1084/jem.20071082
    • K.G. Leong, K. Niessen, I. Kulic, A. Raouf, C. Eaves, I. Pollet, and A. Karsan Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin J. Exp. Med. 204 2007 2935 2948 10.1084/jem.20071082
    • (2007) J. Exp. Med. , vol.204 , pp. 2935-2948
    • Leong, K.G.1    Niessen, K.2    Kulic, I.3    Raouf, A.4    Eaves, C.5    Pollet, I.6    Karsan, A.7
  • 147
    • 1042267263 scopus 로고    scopus 로고
    • Cell adhesion and signalling by cadherins and Ig-CAMs in cancer
    • 10.1038/nrc1276
    • U. Cavallaro, and G. Christofori Cell adhesion and signalling by cadherins and Ig-CAMs in cancer Nat. Rev. Cancer 4 2004 118 132 10.1038/nrc1276
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 118-132
    • Cavallaro, U.1    Christofori, G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.