-
1
-
-
13744263782
-
Hereditary cancer predisposition syndromes
-
Garber JE, Offit K. Hereditary cancer predisposition syndromes. J Clin Oncol 2005;23:276-92.
-
(2005)
J Clin Oncol
, vol.23
, pp. 276-292
-
-
Garber, J.E.1
Offit, K.2
-
2
-
-
0028964341
-
Cloning and characterization of the human invasion suppressor gene E-cadherin (CDH1)
-
Berx G, Staes K, van Hengel J, Molemans F, Bussemakers MJ, van Bokhoven A, van Roy F. Cloning and characterization of the human invasion suppressor gene E-cadherin (CDH1). Genomics 1995;26:281-9.
-
(1995)
Genomics
, vol.26
, pp. 281-289
-
-
Berx, G.1
Staes, K.2
van Hengel, J.3
Molemans, F.4
Bussemakers, M.J.5
van Bokhoven, A.6
van Roy, F.7
-
3
-
-
0027185632
-
From cadherins to catenins: Cytoplasmic protein interactions and regulation of cell adhesion
-
Kemler R. From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion. Trends Genet 1993;9:317-21.
-
(1993)
Trends Genet
, vol.9
, pp. 317-321
-
-
Kemler, R.1
-
4
-
-
0032568370
-
E-cadherin germline mutations in familial gastric cancer
-
Guilford P, Hopkins J, Harraway J, McLeod M, Mcleod N, Harawira P, Taite H, Scoular R, Miller A, Reeve AE. E-cadherin germline mutations in familial gastric cancer. Nature 1998;39:402-5.
-
(1998)
Nature
, vol.39
, pp. 402-405
-
-
Guilford, P.1
Hopkins, J.2
Harraway, J.3
McLeod, M.4
Mcleod, N.5
Harawira, P.6
Taite, H.7
Scoular, R.8
Miller, A.9
Reeve, A.E.10
-
5
-
-
0033432725
-
Familial gastric cancer: Overview and guidelines for management
-
Caldas C, Carneiro F, Lynch HT, Yokota J, Wiesner GL, Powell SM, Lewis FR, Huntsman DG, Pharoah PD, Jankowski JA, MacLeod P, Vogelsang H, Keller G, Park KG, Richards FM, Maher ER, Gayther SA, Oliveira C, Grehan N, Wight D, Seruca R, Roviello F, Ponder BA, Jackson CE. Familial gastric cancer: overview and guidelines for management. J Med Genet 1999;36:873-80.
-
(1999)
J Med Genet
, vol.36
, pp. 873-880
-
-
Caldas, C.1
Carneiro, F.2
Lynch, H.T.3
Yokota, J.4
Wiesner, G.L.5
Powell, S.M.6
Lewis, F.R.7
Huntsman, D.G.8
Pharoah, P.D.9
Jankowski, J.A.10
MacLeod, P.11
Vogelsang, H.12
Keller, G.13
Park, K.G.14
Richards, F.M.15
Maher, E.R.16
Gayther, S.A.17
Oliveira, C.18
Grehan, N.19
Wight, D.20
Seruca, R.21
Roviello, F.22
Ponder, B.A.23
Jackson, C.E.24
more..
-
6
-
-
3142695439
-
-
Brooks-Wilson AR, Kaurah P, Suriano G, Leach S, Senz J, Grehan N, Butterfield YS, Jeyes J, Schinas J, Bacani J, Kelsey M, Ferreira P, MacGillivray B, MacLeod P, Micek M, Ford J, Foulkes W, Australie K, Greenberg C, LaPointe M, Gilpin C, Nikkei S, Gilchrist D, Hughes R, Jackson CE, Monaghan KG, Oliveira MJ, Seruca R, Gallinger S, Caldas C, Huntsman D. Germline E-cadherin mutations in hereditary diffuse gastric cancer: assessment of 42 new families and review of genetic screening criteria. J Med Genet 2004;41:508-17.
-
Brooks-Wilson AR, Kaurah P, Suriano G, Leach S, Senz J, Grehan N, Butterfield YS, Jeyes J, Schinas J, Bacani J, Kelsey M, Ferreira P, MacGillivray B, MacLeod P, Micek M, Ford J, Foulkes W, Australie K, Greenberg C, LaPointe M, Gilpin C, Nikkei S, Gilchrist D, Hughes R, Jackson CE, Monaghan KG, Oliveira MJ, Seruca R, Gallinger S, Caldas C, Huntsman D. Germline E-cadherin mutations in hereditary diffuse gastric cancer: assessment of 42 new families and review of genetic screening criteria. J Med Genet 2004;41:508-17.
-
-
-
-
7
-
-
23044486914
-
-
Suriano G, Yew S, Ferreira P, Senz J, Kaurah P, Ford JM, Longacre TA, Norton JA, Chun N, Young S, Oliveira MJ, Macgillivray B, Rao A, Sears D, Jackson CE, Boyd J, Yee C, Deters C, Pai GS, Hammond LS, McGivern BJ, Medgyesy D, Sartz D, Arun B, Oelschlager BK, Upton MP, Neufeld-Kaiser W, Silva OE, Donenberg TR, Kooby DA, Sharma S, Jonsson BA, Gronberg H, Gallinger S, Seruca R, Lynch H, Huntsman DG. Characterization of a recurrent germ line mutation of the e-cadherin gene: implications for genetic testing and clinical management. Clin Cancer Res 2005;11:5401-9.
-
Suriano G, Yew S, Ferreira P, Senz J, Kaurah P, Ford JM, Longacre TA, Norton JA, Chun N, Young S, Oliveira MJ, Macgillivray B, Rao A, Sears D, Jackson CE, Boyd J, Yee C, Deters C, Pai GS, Hammond LS, McGivern BJ, Medgyesy D, Sartz D, Arun B, Oelschlager BK, Upton MP, Neufeld-Kaiser W, Silva OE, Donenberg TR, Kooby DA, Sharma S, Jonsson BA, Gronberg H, Gallinger S, Seruca R, Lynch H, Huntsman DG. Characterization of a recurrent germ line mutation of the e-cadherin gene: implications for genetic testing and clinical management. Clin Cancer Res 2005;11:5401-9.
-
-
-
-
8
-
-
0035211026
-
Incidence of gastric cancer and breast cancer in CDH1 (E-cadherin) mutation carriers from hereditary diffuse gastric cancer families
-
Pharoah PD, Guilford P, Caldas C. Incidence of gastric cancer and breast cancer in CDH1 (E-cadherin) mutation carriers from hereditary diffuse gastric cancer families. Gastroenterology 2001;121:1348-53.
-
(2001)
Gastroenterology
, vol.121
, pp. 1348-1353
-
-
Pharoah, P.D.1
Guilford, P.2
Caldas, C.3
-
9
-
-
0029558476
-
E-cadherin is a tumour/invasion suppressor gene mutated in human lobular breast cancers
-
Berx G, Cleton-Jansen AM, Nollet F, de Leeuw WJ, van de Vijver M, Cornelisse C, van Roy F. E-cadherin is a tumour/invasion suppressor gene mutated in human lobular breast cancers. Embo J 1995;14:6107-15.
-
(1995)
Embo J
, vol.14
, pp. 6107-6115
-
-
Berx, G.1
Cleton-Jansen, A.M.2
Nollet, F.3
de Leeuw, W.J.4
van de Vijver, M.5
Cornelisse, C.6
van Roy, F.7
-
10
-
-
0035932396
-
E-cadherin gene (CDH1) promoter methylation as the second hit in sporadic diffuse gastric carcinoma
-
Machado JC, Oliveira C, Carvalho R, Soares P, Berx G, Caldas C, Seruca R, Carneiro F, Sobrinho-Simoes M. E-cadherin gene (CDH1) promoter methylation as the second hit in sporadic diffuse gastric carcinoma. Oncogene 2001;20:1525-8.
-
(2001)
Oncogene
, vol.20
, pp. 1525-1528
-
-
Machado, J.C.1
Oliveira, C.2
Carvalho, R.3
Soares, P.4
Berx, G.5
Caldas, C.6
Seruca, R.7
Carneiro, F.8
Sobrinho-Simoes, M.9
-
11
-
-
0029951738
-
E-cadherin is inactivated in a majority of invasive human lobular breast cancers by truncation mutations throughout its extracellular domain
-
Berx G, Cleton-Jansen AM, Strumane K, de Leeuw WJ, Nollet F, van Roy F, Cornelisse C. E-cadherin is inactivated in a majority of invasive human lobular breast cancers by truncation mutations throughout its extracellular domain. Oncogene 1996;13:1919-25.
-
(1996)
Oncogene
, vol.13
, pp. 1919-1925
-
-
Berx, G.1
Cleton-Jansen, A.M.2
Strumane, K.3
de Leeuw, W.J.4
Nollet, F.5
van Roy, F.6
Cornelisse, C.7
-
12
-
-
0032806475
-
Diffuse type gastric and lobular breast carcinoma in a familial gastric cancer patient with an E-cadherin germline mutation
-
Keller G, Vogelsang H, Becker I, Hutter J, Ott K, Candidus S, Grundei T, Becker KF, Mueller J, Siewert JR, Hofler H. Diffuse type gastric and lobular breast carcinoma in a familial gastric cancer patient with an E-cadherin germline mutation. Am J Pathol 1999;155:337-42.
-
(1999)
Am J Pathol
, vol.155
, pp. 337-342
-
-
Keller, G.1
Vogelsang, H.2
Becker, I.3
Hutter, J.4
Ott, K.5
Candidus, S.6
Grundei, T.7
Becker, K.F.8
Mueller, J.9
Siewert, J.R.10
Hofler, H.11
-
13
-
-
34249989159
-
-
Kaurah P, MacMillan A, Boyd N, Senz J, De Luca A, Chun N, Suriano G, Zaor S, Van Manen L, Gilpin C, Nikkel S, Connolly-Wilson M, Weissman S, Rubinstein WS, Sebold C, Greenstein R, Stroop J, Yim D, Panzini B, McKinnon W, Greenblatt M, Wirtzfeld D, Fontaine D, Coit D, Yoon S, Chung D, Lauwers G, Pizzuti A, Vaccaro C, Redal MA, Oliveira C, Tischkowitz M, Olschwang S, Gallinger S, Lynch H, Green J, Ford J, Pharoah P, Fernandez B, Huntsman D. Founder and recurrent CDH1 mutations in families with hereditary diffuse gastric cancer. JAMA 2007;297:2360-72.
-
Kaurah P, MacMillan A, Boyd N, Senz J, De Luca A, Chun N, Suriano G, Zaor S, Van Manen L, Gilpin C, Nikkel S, Connolly-Wilson M, Weissman S, Rubinstein WS, Sebold C, Greenstein R, Stroop J, Yim D, Panzini B, McKinnon W, Greenblatt M, Wirtzfeld D, Fontaine D, Coit D, Yoon S, Chung D, Lauwers G, Pizzuti A, Vaccaro C, Redal MA, Oliveira C, Tischkowitz M, Olschwang S, Gallinger S, Lynch H, Green J, Ford J, Pharoah P, Fernandez B, Huntsman D. Founder and recurrent CDH1 mutations in families with hereditary diffuse gastric cancer. JAMA 2007;297:2360-72.
-
-
-
-
14
-
-
17744386128
-
Low frequency of E-cadherin alterations in familial breast cancer
-
Salahshor S, Haixin L, Huo H, Kristensen VN, Loman N, Sjoberg-Margolin S, Bora A, Borresen-Dale AL, Vorechovsky I, Lindblom A. Low frequency of E-cadherin alterations in familial breast cancer. Breast Cancer Res 2001;3:199-207.
-
(2001)
Breast Cancer Res
, vol.3
, pp. 199-207
-
-
Salahshor, S.1
Haixin, L.2
Huo, H.3
Kristensen, V.N.4
Loman, N.5
Sjoberg-Margolin, S.6
Bora, A.7
Borresen-Dale, A.L.8
Vorechovsky, I.9
Lindblom, A.10
-
15
-
-
33644644574
-
E-cadherin status in breast cancer correlates with histological type but does not correlate with established prognostic parameters
-
Qureshi HS, Linden MD, Divine G, Raju UB. E-cadherin status in breast cancer correlates with histological type but does not correlate with established prognostic parameters. Am J Clin Pathol 2006;125:377- 85.
-
(2006)
Am J Clin Pathol
, vol.125
, pp. 377-385
-
-
Qureshi, H.S.1
Linden, M.D.2
Divine, G.3
Raju, U.B.4
-
16
-
-
0037051099
-
CDH1 mutations are present in both ductal and lobular breast cancer, but promoter allelic variants show no detectable breast cancer risk
-
Lei H, Sjoberg-Margolin S, Salahshor S, Werelius B, Jandakova E, Hemminki K, Lindblom A, Vorechovsky I. CDH1 mutations are present in both ductal and lobular breast cancer, but promoter allelic variants show no detectable breast cancer risk. Int J Cancer 2002;98:199-204.
-
(2002)
Int J Cancer
, vol.98
, pp. 199-204
-
-
Lei, H.1
Sjoberg-Margolin, S.2
Salahshor, S.3
Werelius, B.4
Jandakova, E.5
Hemminki, K.6
Lindblom, A.7
Vorechovsky, I.8
-
17
-
-
0033953546
-
Lobular carcinoma in situ of the breast is not caused by constitutional mutations in the E-cadherin gene
-
Rahman N, Stone JG, Coleman G, Gusterson B, Seal S, Marossy A, Lakhani SR, Ward A, Nash A, McKinna A, A'Hern R, Stratton MR, Houlston RS. Lobular carcinoma in situ of the breast is not caused by constitutional mutations in the E-cadherin gene. Br J Cancer 2000;82:568-70.
-
(2000)
Br J Cancer
, vol.82
, pp. 568-570
-
-
Rahman, N.1
Stone, J.G.2
Coleman, G.3
Gusterson, B.4
Seal, S.5
Marossy, A.6
Lakhani, S.R.7
Ward, A.8
Nash, A.9
McKinna, A.10
A'Hern, R.11
Stratton, M.R.12
Houlston, R.S.13
-
18
-
-
0037479867
-
Epigenetic and genetic alterations of APC and CDH1 genes in lobular breast cancer: Relationships with abnormal E-cadherin and catenin expression and microsatellite instability
-
Sarrio D, Moreno-Bueno G, Hardisson D, Sanchez-Estevez C, Guo M, Herman JG, Gamallo C, Esteller M, Palacios J. Epigenetic and genetic alterations of APC and CDH1 genes in lobular breast cancer: relationships with abnormal E-cadherin and catenin expression and microsatellite instability. Int J Cancer 2003;106:208-15.
-
(2003)
Int J Cancer
, vol.106
, pp. 208-215
-
-
Sarrio, D.1
Moreno-Bueno, G.2
Hardisson, D.3
Sanchez-Estevez, C.4
Guo, M.5
Herman, J.G.6
Gamallo, C.7
Esteller, M.8
Palacios, J.9
-
19
-
-
0033822499
-
Mechanism of homophilic cadherin adhesion
-
Leckband D, Sivasankar S. Mechanism of homophilic cadherin adhesion. Curr Opin Cell Biol 2000;12:587-92.
-
(2000)
Curr Opin Cell Biol
, vol.12
, pp. 587-592
-
-
Leckband, D.1
Sivasankar, S.2
-
20
-
-
1042267263
-
Cell adhesion and signalling by cadherins and Ig-CAMs in cancer
-
Cavallaro U, Christofori G. Cell adhesion and signalling by cadherins and Ig-CAMs in cancer. Nat Rev Cancer 2004;4:118-32.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 118-132
-
-
Cavallaro, U.1
Christofori, G.2
-
21
-
-
1842591223
-
Intragenic deletion of CDH1 as the inactivating mechanism of the wild-type allele in an HDGC tumour
-
Oliveira C, de Bruin J, Nabais S, Ligtenberg M, Moutinho C, Nagengast FM, Seruca R, van Krieken H, Carneiro F. Intragenic deletion of CDH1 as the inactivating mechanism of the wild-type allele in an HDGC tumour. Oncogene 2004;23:2236-40.
-
(2004)
Oncogene
, vol.23
, pp. 2236-2240
-
-
Oliveira, C.1
de Bruin, J.2
Nabais, S.3
Ligtenberg, M.4
Moutinho, C.5
Nagengast, F.M.6
Seruca, R.7
van Krieken, H.8
Carneiro, F.9
-
22
-
-
0035342577
-
Multiple ways of silencing E-cadherin gene expression in lobular carcinoma of the breast
-
Droufakou S, Deshmane V, Roylance R, Hanby A, Tomlinson I, Hart IR. Multiple ways of silencing E-cadherin gene expression in lobular carcinoma of the breast. Int J Cancer 2001;92:404-8.
-
(2001)
Int J Cancer
, vol.92
, pp. 404-408
-
-
Droufakou, S.1
Deshmane, V.2
Roylance, R.3
Hanby, A.4
Tomlinson, I.5
Hart, I.R.6
-
23
-
-
0033816924
-
Methylation of the CDH1 promoter as the second genetic hit in hereditary diffuse gastric cancer
-
Grady WM, Willis J, Guilford PJ, Dunbier AK, Toro TT, Lynch H, Wiesner G, Ferguson K, Eng C, Park JG, Kim SJ, Markowitz S. Methylation of the CDH1 promoter as the second genetic hit in hereditary diffuse gastric cancer. Nat Genet 2000;26:16-17.
-
(2000)
Nat Genet
, vol.26
, pp. 16-17
-
-
Grady, W.M.1
Willis, J.2
Guilford, P.J.3
Dunbier, A.K.4
Toro, T.T.5
Lynch, H.6
Wiesner, G.7
Ferguson, K.8
Eng, C.9
Park, J.G.10
Kim, S.J.11
Markowitz, S.12
-
24
-
-
12944286550
-
The pathology of familial breast cancer: Histological features of cancers in families not attributable to mutations in BRCA1 or BRCA2
-
Lakhani SR, Gusterson BA, Jacquemier J, Sloane JP, Anderson TJ, van de Vijver MJ, Venter D, Freeman A, Antoniou A, McGuffog L, Smyth E, Steel CM, Haites N, Scott RJ, Goldgar D, Neuhausen S, Daly PA, Ormiston W, McManus R, Scherneck S, Ponder BA, Futreal PA, Peto J, Stoppa-Lyonnet D, Bignon YJ, Stratton MR. The pathology of familial breast cancer: histological features of cancers in families not attributable to mutations in BRCA1 or BRCA2. Clin Cancer Res 2000;6:782-9.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 782-789
-
-
Lakhani, S.R.1
Gusterson, B.A.2
Jacquemier, J.3
Sloane, J.P.4
Anderson, T.J.5
van de Vijver, M.J.6
Venter, D.7
Freeman, A.8
Antoniou, A.9
McGuffog, L.10
Smyth, E.11
Steel, C.M.12
Haites, N.13
Scott, R.J.14
Goldgar, D.15
Neuhausen, S.16
Daly, P.A.17
Ormiston, W.18
McManus, R.19
Scherneck, S.20
Ponder, B.A.21
Futreal, P.A.22
Peto, J.23
Stoppa-Lyonnet, D.24
Bignon, Y.J.25
Stratton, M.R.26
more..
-
25
-
-
0242608613
-
The genetic basis of cancer of the kidney
-
Linehan WM, Walther MM, Zbar B. The genetic basis of cancer of the kidney. J Urol 2003;170:2163-72.
-
(2003)
J Urol
, vol.170
, pp. 2163-2172
-
-
Linehan, W.M.1
Walther, M.M.2
Zbar, B.3
-
26
-
-
0036569877
-
The pathology of familial breast cancer: Predictive value of immunohistochemical markers estrogen receptor, progesterone receptor, HER-2, and p53 in patients with mutations in BRCA1 and BRCA2
-
Lakhani SR, Van De Vijver MJ, Jacquemier J, Anderson TJ, Osin PP, McGuffog L, Easton DF. The pathology of familial breast cancer: predictive value of immunohistochemical markers estrogen receptor, progesterone receptor, HER-2, and p53 in patients with mutations in BRCA1 and BRCA2. J Clin Oncol 2002;20:2310-18.
-
(2002)
J Clin Oncol
, vol.20
, pp. 2310-2318
-
-
Lakhani, S.R.1
Van De Vijver, M.J.2
Jacquemier, J.3
Anderson, T.J.4
Osin, P.P.5
McGuffog, L.6
Easton, D.F.7
-
27
-
-
36349033681
-
-
Kandel MJ, Stadler Z, Masciari S, Collins L, Schnitt S, Harris L, Miron A, Richardson A, Garber JE. Prevalence of BRCA1 mutations in triple negative breast cancer (BC). J Clin Oncol ASCO Annual Meeting Proceedings Part I 2006;24(Suppl:), 508.
-
Kandel MJ, Stadler Z, Masciari S, Collins L, Schnitt S, Harris L, Miron A, Richardson A, Garber JE. Prevalence of BRCA1 mutations in triple negative breast cancer (BC). J Clin Oncol ASCO Annual Meeting Proceedings Part I 2006;24(Suppl:), 508.
-
-
-
-
28
-
-
3142765936
-
Infiltrating lobular carcinoma of the breast: Tumor characteristics and clinical outcome
-
Arpino G, Bardou VJ, Clark GM, Elledge RM. Infiltrating lobular carcinoma of the breast: tumor characteristics and clinical outcome. Breast Cancer Res 2004;6:R149-56.
-
(2004)
Breast Cancer Res
, vol.6
-
-
Arpino, G.1
Bardou, V.J.2
Clark, G.M.3
Elledge, R.M.4
-
29
-
-
0035927967
-
Early gastric cancer in young, asymptomatic carriers of germ-line E-cadherin mutations
-
Huntsman DG, Carneiro F, Lewis FR, MacLeod PM, Hayashi A, Monaghan KG, Maung R, Seruca R, Jackson CE, Caldas C. Early gastric cancer in young, asymptomatic carriers of germ-line E-cadherin mutations. N Engl J Med 2001;344:1904-9.
-
(2001)
N Engl J Med
, vol.344
, pp. 1904-1909
-
-
Huntsman, D.G.1
Carneiro, F.2
Lewis, F.R.3
MacLeod, P.M.4
Hayashi, A.5
Monaghan, K.G.6
Maung, R.7
Seruca, R.8
Jackson, C.E.9
Caldas, C.10
-
30
-
-
34249302080
-
CDH1 truncating mutations in the E-cadherin gene: An indication for total gastrectomy to treat hereditary diffuse gastric cancer
-
Norton JA, Ham CM, Van Dam J, Jeffrey RB, Longacre TA, Huntsman DG, Chun N, Kurian AW, Ford JM. CDH1 truncating mutations in the E-cadherin gene: an indication for total gastrectomy to treat hereditary diffuse gastric cancer. Ann Surg 2007;245:873-9.
-
(2007)
Ann Surg
, vol.245
, pp. 873-879
-
-
Norton, J.A.1
Ham, C.M.2
Van Dam, J.3
Jeffrey, R.B.4
Longacre, T.A.5
Huntsman, D.G.6
Chun, N.7
Kurian, A.W.8
Ford, J.M.9
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