Helicobacter pylori HtrA is a new secreted virulence factor that cleaves E-cadherin to disrupt intercellular adhesion

EMBO Reports

Volumn 11, Issue 10, 2010, Pages 798-804

  Hoy, Benjamin ^a   Löwer, Martin ^b   Weydig, Christiane ^a   Carra, Gert ^a   Tegtmeyer, Nicole ^c   Geppert, Tim ^d   Schröder, Peter ^e   Sewald, Norbert ^e   Backert, Steffen ^c   Schneider, Gisbert ^b,d   Wessler, Silja ^a,f  

^a PAUL EHRLICH INSTITUT   (Germany)

^b GOETHE UNIVERSITY   (Germany)

^c UNIVERSITY COLLEGE DUBLIN   (Ireland)

^d ETH ZURICH   (Switzerland)

^e BIELEFELD UNIVERSITY   (Germany)

^f UNIVERSITY OF SALZBURG   (Austria)

Author keywords

E cadherin; H. pylori; HtrA

Indexed keywords

HIGH TEMPERATURE REQUIREMENT A PROTEIN; SERINE PROTEINASE; UNCLASSIFIED DRUG; UVOMORULIN; VIRULENCE FACTOR;

ARTICLE; CELL ADHESION; CELL POLARITY; EPITHELIUM CELL; HELICOBACTER PYLORI; INTERCELLULAR SPACE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN SECRETION; PROTEIN STRUCTURE;

BACTERIAL ADHESION; BACTERIAL OUTER MEMBRANE PROTEINS; BLOTTING, WESTERN; CADHERINS; CELL ADHESION MOLECULES; CELL LINE, TUMOR; EPITHELIAL CELLS; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; VIRULENCE FACTORS;

HELICOBACTER PYLORI; MAMMALIA; PROKARYOTA;

EID: 77957232471     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.1038/embor.2010.114     Document Type: Article

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