E-cadherin destabilization accounts for the pathogenicity of missense mutations in hereditary diffuse gastric cancer

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  Simões Correia, Joana ^a,b,d   Figueiredo, Joana ^a,c   Lopes, Rui ^a   Stricher, François ^d   Oliveira, Carla ^a,c   Serrano, Luis ^d,e   Seruca, Raquel ^a,c  

^a UNIVERSITY OF PORTO   (Portugal)

^b UNIVERSITY OF COIMBRA   (Portugal)

^c University of Porto   (Portugal)

^d CENTRE FOR GENOMIC REGULATION CRG   (Spain)

^e INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEASOME; UVOMORULIN; CADHERIN;

AGE DISTRIBUTION; ANIMAL CELL; ARTICLE; CARCINOGENICITY; COMPUTER MODEL; FEMALE; GENETIC CONSERVATION; GENETIC STABILITY; HALF LIFE TIME; HEREDITARY DIFFUSE GASTRIC CANCER; IN VITRO STUDY; IN VIVO STUDY; LOSS OF FUNCTION MUTATION; MISSENSE MUTATION; MUTANT; NONHUMAN; PROTEIN DEGRADATION; PROTEIN STRUCTURE; STOMACH CANCER; ALGORITHM; AMINO ACID SEQUENCE; ANIMAL; CHEMICAL STRUCTURE; CHO CELL; CRICETULUS; GENETICS; HAMSTER; HUMAN; METABOLISM; MOLECULAR GENETICS; PATHOLOGY; STOMACH TUMOR;

ALGORITHMS; AMINO ACID SEQUENCE; ANIMALS; CADHERINS; CHO CELLS; CRICETINAE; CRICETULUS; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; STOMACH NEOPLASMS;

EID: 84858685771     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0033783     Document Type: Article

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