Decreased VEGF expression and microvascular density, but increased HIF-1 and 2α accumulation and EPO expression in chronic moderate hyperoxia in the mouse brain

Brain Research

Volumn 1471, Issue , 2012, Pages 46-55

  Benderro, Girriso F ^a   Sun, Xiaoyan ^b   Kuang, Youzhi ^b   Lamanna, Joseph C ^b  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Ang 2; Brain angioplasticity; COX 2; PGC 1 ; PHD 2

Indexed keywords

ANGIOPOIETIN 2; CYCLOOXYGENASE 2; ERYTHROPOIETIN; HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 2ALPHA; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2; VON HIPPEL LINDAU PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL PARAMETERS; BRAIN; BRAIN TISSUE; CONTROLLED STUDY; HYPEROXIA; IMMUNOHISTOCHEMISTRY; MALE; MICROVASCULAR DENSITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANGIOPOIETIN-2; ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BODY WEIGHT; CEREBRAL CORTEX; CYCLOOXYGENASE 2; DISEASE MODELS, ANIMAL; ERYTHROPOIETIN; GENE EXPRESSION REGULATION; HEMATOCRIT; HYPEROXIA; HYPOXIA-INDUCIBLE FACTOR 1; MALE; MICE; MICE, INBRED C57BL; MICROVESSELS; OXYGEN; RNA, MESSENGER; TIME FACTORS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

MUS;

EID: 84864699868     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2012.06.055     Document Type: Article

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