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Volumn 1389, Issue , 2011, Pages 50-60

Hypoxia-induced angiogenesis is delayed in aging mouse brain

Author keywords

Ang 2; Brain capillary density; COX 2; HIF 1; VEGF

Indexed keywords

ANGIOPOIETIN 2; CYCLOOXYGENASE 2; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; VASCULOTROPIN;

EID: 79955483643     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2011.03.016     Document Type: Article
Times cited : (59)

References (61)
  • 1
    • 70450184309 scopus 로고    scopus 로고
    • Impaired expression of neuroprotective molecules in the HIF-1alpha pathway following traumatic brain injury in aged mice
    • J. Anderson, R. Sandhir, E.S. Hamilton, and N.E. Berman Impaired expression of neuroprotective molecules in the HIF-1alpha pathway following traumatic brain injury in aged mice J. Neurotrauma 26 2009 1557 1566
    • (2009) J. Neurotrauma , vol.26 , pp. 1557-1566
    • Anderson, J.1    Sandhir, R.2    Hamilton, E.S.3    Berman, N.E.4
  • 3
    • 0030865278 scopus 로고    scopus 로고
    • Vascular endothelial growth factor increases microvascular permeability via a Ca(2+)-dependent pathway
    • D.O. Bates, and F.E. Curry Vascular endothelial growth factor increases microvascular permeability via a Ca(2+)-dependent pathway Am. J. Physiol. 273 1997 H687 H694
    • (1997) Am. J. Physiol. , vol.273
    • Bates, D.O.1    Curry, F.E.2
  • 4
    • 33747152779 scopus 로고    scopus 로고
    • Cytokines and chemokines as regulators of angiogenesis in health and disease
    • DOI 10.2174/138161206777947461
    • R. Benelli, G. Lorusso, A. Albini, and D.M. Noonan Cytokines and chemokines as regulators of angiogenesis in health and disease Curr. Pharm. Des. 12 2006 3101 3115 (Pubitemid 44227572)
    • (2006) Current Pharmaceutical Design , vol.12 , Issue.24 , pp. 3101-3115
    • Benelli, R.1    Lorusso, G.2    Albini, A.3    Noonan, D.M.4
  • 7
    • 0037699955 scopus 로고    scopus 로고
    • Angiogenesis in health and disease
    • DOI 10.1038/nm0603-653
    • P. Carmeliet Angiogenesis in health and disease Nat. Med. 9 2003 653 660 (Pubitemid 36749213)
    • (2003) Nature Medicine , vol.9 , Issue.6 , pp. 653-660
    • Carmeliet, P.1
  • 8
    • 1342329226 scopus 로고    scopus 로고
    • Molecular and morphological modifications occurring in rat heart exposed to intermittent hypoxia: Role for protein kinase C α
    • DOI 10.1016/j.exger.2003.11.010
    • A. Cataldi, G. Bianchi, C. Rapino, N. Sabatini, L. Centurione, G.C. Di, D. Bosco, and A. Antonucci Molecular and morphological modifications occurring in rat heart exposed to intermittent hypoxia: role for protein kinase C alpha Exp. Gerontol. 39 2004 395 405 (Pubitemid 38264370)
    • (2004) Experimental Gerontology , vol.39 , Issue.3 , pp. 395-405
    • Cataldi, A.1    Bianchi, G.2    Rapino, C.3    Sabatini, N.4    Centurione, L.5    Di Giulio, C.6    Bosco, D.7    Antonucci, A.8
  • 9
    • 37349021749 scopus 로고    scopus 로고
    • Age decreases endothelial progenitor cell recruitment through decreases in hypoxia-inducible factor 1α stabilization during ischemia
    • DOI 10.1161/CIRCULATIONAHA.107.715847
    • E.I. Chang, S.A. Loh, D.J. Ceradini, E.I. Chang, S.E. Lin, N. Bastidas, S. Aarabi, D.A. Chan, M.L. Freedman, A.J. Giaccia, and G.C. Gurtner Age decreases endothelial progenitor cell recruitment through decreases in hypoxia-inducible factor 1alpha stabilization during ischemia Circulation 116 2007 2818 2829 (Pubitemid 350291224)
    • (2007) Circulation , vol.116 , Issue.24 , pp. 2818-2829
    • Chang, E.I.1    Loh, S.A.2    Ceradini, D.J.3    Chang, E.I.4    Lin, S.-E.5    Bastidas, N.6    Aarabi, S.7    Chan, D.A.8    Freedman, M.L.9    Giaccia, A.J.10    Gurtner, G.C.11
  • 10
    • 0033763820 scopus 로고    scopus 로고
    • Expression of hypoxia-inducible factor-1alpha in the brain of rats during chronic hypoxia
    • J.C. Chavez, F. Agani, P. Pichiule, and J.C. LaManna Expression of hypoxia-inducible factor-1alpha in the brain of rats during chronic hypoxia J. Appl. Physiol. 89 2000 1937 1942
    • (2000) J. Appl. Physiol. , vol.89 , pp. 1937-1942
    • Chavez, J.C.1    Agani, F.2    Pichiule, P.3    Lamanna, J.C.4
  • 11
    • 33748714735 scopus 로고    scopus 로고
    • The transcriptional activator hypoxia inducible factor 2 (HIF-2/EPAS-1) regulates the oxygen-dependent expression of erythropoietin in cortical astrocytes
    • DOI 10.1523/JNEUROSCI.2838-06.2006
    • J.C. Chavez, O. Baranova, J. Lin, and P. Pichiule The transcriptional activator hypoxia inducible factor 2 (HIF-2/EPAS-1) regulates the oxygen-dependent expression of erythropoietin in cortical astrocytes J. Neurosci. 26 2006 9471 9481 (Pubitemid 44396860)
    • (2006) Journal of Neuroscience , vol.26 , Issue.37 , pp. 9471-9481
    • Chavez, J.C.1    Baranova, O.2    Lin, J.3    Pichiule, P.4
  • 12
    • 0037223713 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1α accumulation in the rat brain in response to hypoxia and ischemia is attenuated during aging
    • J.C. Chavez, and J.C. LaManna Hypoxia-inducible factor-1alpha accumulation in the rat brain in response to hypoxia and ischemia is attenuated during aging Adv. Exp. Med. Biol. 510 2003 337 341 (Pubitemid 36307798)
    • (2003) Advances in Experimental Medicine and Biology , vol.510 , pp. 337-341
    • Chavez, J.C.1    LaManna, J.C.2
  • 15
    • 34547916146 scopus 로고    scopus 로고
    • Physiologic angiodynamics in the brain
    • DOI 10.1089/ars.2007.1713
    • P. Dore-Duffy, and J.C. LaManna Physiologic angiodynamics in the brain Antioxid. Redox Signal. 9 2007 1363 1371 (Pubitemid 47255015)
    • (2007) Antioxidants and Redox Signaling , vol.9 , Issue.9 , pp. 1363-1371
    • Dore-Duffy, P.1    LaManna, J.C.2
  • 16
    • 33344477298 scopus 로고    scopus 로고
    • Tie receptors and their angiopoietin ligands are context-dependent regulators of vascular remodeling
    • DOI 10.1016/j.yexcr.2005.09.002, PII S0014482705004143
    • L. Eklund, and B.R. Olsen Tie receptors and their angiopoietin ligands are context-dependent regulators of vascular remodeling Exp. Cell Res. 312 2006 630 641 (Pubitemid 43290339)
    • (2006) Experimental Cell Research , vol.312 , Issue.5 , pp. 630-641
    • Eklund, L.1    Olsen, B.R.2
  • 18
    • 0037699954 scopus 로고    scopus 로고
    • The biology of VEGF and its receptors
    • DOI 10.1038/nm0603-669
    • N. Ferrara, H.P. Gerber, and J. LeCouter The biology of VEGF and its receptors Nat. Med. 9 2003 669 676 (Pubitemid 36749215)
    • (2003) Nature Medicine , vol.9 , Issue.6 , pp. 669-676
    • Ferrara, N.1    Gerber, H.-P.2    LeCouter, J.3
  • 19
    • 0031039243 scopus 로고    scopus 로고
    • The biology of vascular endothelial growth factor
    • DOI 10.1210/er.18.1.4
    • N. Ferrara, and T. vis-Smyth The biology of vascular endothelial growth factor Endocr. Rev. 18 1997 4 25 (Pubitemid 27076453)
    • (1997) Endocrine Reviews , vol.18 , Issue.1 , pp. 4-25
    • Ferrara, N.1    Davis-Smyth, T.2
  • 20
    • 0032748767 scopus 로고    scopus 로고
    • The function of hypoxia-inducible factor 1 (HIF-1) is impaired in senescent mice
    • G. Frenkel-Denkberg, D. Gershon, and A.P. Levy The function of hypoxia-inducible factor 1 (HIF-1) is impaired in senescent mice FEBS Lett. 462 1999 341 344
    • (1999) FEBS Lett. , vol.462 , pp. 341-344
    • Frenkel-Denkberg, G.1    Gershon, D.2    Levy, A.P.3
  • 21
    • 0032557564 scopus 로고    scopus 로고
    • Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1 in vascular endothelial cells
    • DOI 10.1074/jbc.273.21.13313
    • H.P. Gerber, V. Dixit, and N. Ferrara Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1 in vascular endothelial cells J. Biol. Chem. 273 1998 13313 13316 (Pubitemid 28246905)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.21 , pp. 13313-13316
    • Gerber, H.-P.1    Dixit, V.2    Ferrara, N.3
  • 22
    • 15944397647 scopus 로고    scopus 로고
    • Cytokines and the regulation of hypoxia-inducible factor (HIF)-1α
    • DOI 10.1016/j.intimp.2004.11.009
    • J.J. Haddad, and H.L. Harb Cytokines and the regulation of hypoxia-inducible factor (HIF)-1alpha Int. Immunopharmacol. 5 2005 461 483 (Pubitemid 40430755)
    • (2005) International Immunopharmacology , vol.5 , Issue.3 , pp. 461-483
    • Haddad, J.J.1    Harb, H.L.2
  • 23
    • 33646248422 scopus 로고    scopus 로고
    • Differential regulation of the transcriptional activities of hypoxia-inducible factor 1 alpha (HIF-1alpha) and HIF-2alpha in stem cells
    • C.J. Hu, S. Iyer, A. Sataur, K.L. Covello, L.A. Chodosh, and M.C. Simon Differential regulation of the transcriptional activities of hypoxia-inducible factor 1 alpha (HIF-1alpha) and HIF-2alpha in stem cells Mol. Cell. Biol. 26 2006 3514 3526
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 3514-3526
    • Hu, C.J.1    Iyer, S.2    Sataur, A.3    Covello, K.L.4    Chodosh, L.A.5    Simon, M.C.6
  • 24
    • 0036420517 scopus 로고    scopus 로고
    • How mitochondrial damage affects cell function
    • A.M. James, and M.P. Murphy How mitochondrial damage affects cell function J. Biomed. Sci. 9 2002 475 487 (Pubitemid 35316860)
    • (2002) Journal of Biomedical Science , vol.9 , Issue.5-6 , pp. 475-487
    • James, A.M.1    Murphy, M.P.2
  • 25
    • 33646764620 scopus 로고    scopus 로고
    • Is there a molecular connection between hypoxia and aging?
    • DOI 10.1016/j.exger.2005.12.003, PII S0531556505003153
    • D.M. Katschinski Is there a molecular connection between hypoxia and aging? Exp. Gerontol. 41 2006 482 484 (Pubitemid 43765900)
    • (2006) Experimental Gerontology , vol.41 , Issue.5 , pp. 482-484
    • Katschinski, D.M.1
  • 26
    • 4644371659 scopus 로고    scopus 로고
    • Structural and functional adaptation to hypoxia in the rat brain
    • DOI 10.1242/jeb.00976
    • J.C. LaManna, J.C. Chavez, and P. Pichiule Structural and functional adaptation to hypoxia in the rat brain J. Exp. Biol. 207 2004 3163 3169 (Pubitemid 39275291)
    • (2004) Journal of Experimental Biology , vol.207 , Issue.18 , pp. 3163-3169
    • LaManna, J.C.1    Chavez, J.C.2    Pichiule, P.3
  • 27
    • 84934442810 scopus 로고    scopus 로고
    • Is cycloxygenase-2 (COX-2) a major component of the mechanism responsible for microvascular remodeling in the brain?
    • J.C. LaManna, X. Sun, A.D. Ivy, and N.L. Ward Is cycloxygenase-2 (COX-2) a major component of the mechanism responsible for microvascular remodeling in the brain? Adv. Exp. Med. Biol. 578 2006 297 303
    • (2006) Adv. Exp. Med. Biol. , vol.578 , pp. 297-303
    • Lamanna, J.C.1    Sun, X.2    Ivy, A.D.3    Ward, N.L.4
  • 28
    • 0015217907 scopus 로고
    • Adaptation to high altitude
    • C. Lenfant, and K. Sullivan Adaptation to high altitude N. Engl. J. Med. 284 1971 1298 1309
    • (1971) N. Engl. J. Med. , vol.284 , pp. 1298-1309
    • Lenfant, C.1    Sullivan, K.2
  • 29
    • 77953135754 scopus 로고    scopus 로고
    • Integrity of the prolyl hydroxylase domain protein 2:erythropoietin pathway in aging mice
    • X. Li, S. Sutherland, K. Takeda, G.H. Fong, and F.S. Lee Integrity of the prolyl hydroxylase domain protein 2:erythropoietin pathway in aging mice Blood Cells Mol. Dis. 45 2010 9 19
    • (2010) Blood Cells Mol. Dis. , vol.45 , pp. 9-19
    • Li, X.1    Sutherland, S.2    Takeda, K.3    Fong, G.H.4    Lee, F.S.5
  • 31
    • 2142771727 scopus 로고    scopus 로고
    • Prostanoids, Not Reactive Oxygen Species, Mediate COX-2-Dependent Neurotoxicity
    • DOI 10.1002/ana.20078
    • Y. Manabe, J. Anrather, T. Kawano, K. Niwa, P. Zhou, M.E. Ross, and C. Iadecola Prostanoids, not reactive oxygen species, mediate COX-2-dependent neurotoxicity Ann. Neurol. 55 2004 668 675 (Pubitemid 38544327)
    • (2004) Annals of Neurology , vol.55 , Issue.5 , pp. 668-675
    • Manabe, Y.1    Anrather, J.2    Kawano, T.3    Niwa, K.4    Zhou, P.5    Ross, M.E.6    Iadecola, C.7
  • 32
    • 33845985586 scopus 로고    scopus 로고
    • Aging stimulates cyclooxygenase-2 expression and prostaglandin E2 production in human periodontal ligament cells after the application of compressive force
    • K. Mayahara, Y. Kobayashi, K. Takimoto, N. Suzuki, N. Mitsui, and N. Shimizu Aging stimulates cyclooxygenase-2 expression and prostaglandin E2 production in human periodontal ligament cells after the application of compressive force J. Periodontal Res. 42 2007 8 14
    • (2007) J. Periodontal Res. , vol.42 , pp. 8-14
    • Mayahara, K.1    Kobayashi, Y.2    Takimoto, K.3    Suzuki, N.4    Mitsui, N.5    Shimizu, N.6
  • 33
    • 0028337253 scopus 로고
    • Metabolism and ventilation in hypoxic rats: Effect of body mass
    • DOI 10.1016/0034-5687(94)90028-0
    • J.P. Mortola, T. Matsuoka, C. Saiki, and L. Naso Metabolism and ventilation in hypoxic rats: effect of body mass Respir. Physiol. 97 1994 225 234 (Pubitemid 24223397)
    • (1994) Respiration Physiology , vol.97 , Issue.2 , pp. 225-234
    • Mortola, J.P.1    Matsuoka, T.2    Saiki, C.3    Naso, L.4
  • 35
    • 67650065272 scopus 로고    scopus 로고
    • Increased prolyl 4-hydroxylase (PHD) expression and differential regulation of hypoxia inducible factors (HIFs) in the aged rat brain
    • O.I. Ndubuizu, J.C. Chavez, and J.C. LaManna Increased prolyl 4-hydroxylase (PHD) expression and differential regulation of hypoxia inducible factors (HIFs) in the aged rat brain Am. J. Physiol. Regul. Integr. Comp. Physiol. 279 2009 R158 R165
    • (2009) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.279
    • Ndubuizu, O.I.1    Chavez, J.C.2    Lamanna, J.C.3
  • 36
    • 79251604405 scopus 로고    scopus 로고
    • Hypoxia inducible factor-1 (HIF-1) independent microvascular angiogenesis in the aged rat brain
    • O.I. Ndubuizu, C.P. Tsipis, A. Li, and J.C. LaManna Hypoxia inducible factor-1 (HIF-1) independent microvascular angiogenesis in the aged rat brain Brain Res. 1366 2010 101 109
    • (2010) Brain Res. , vol.1366 , pp. 101-109
    • Ndubuizu, O.I.1    Tsipis, C.P.2    Li, A.3    Lamanna, J.C.4
  • 37
    • 1842478183 scopus 로고    scopus 로고
    • Hypoxic Regulation of Angiopoietin-2 Expression in Endothelial Cells
    • DOI 10.1074/jbc.M305146200
    • P. Pichiule, J.C. Chavez, and J.C. LaManna Hypoxic regulation of angiopoietin-2 expression in endothelial cells J. Biol. Chem. 279 2004 12171 12180 (Pubitemid 38445782)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.13 , pp. 12171-12180
    • Pichiule, P.1    Chavez, J.C.2    LaManna, J.C.3
  • 38
    • 0036707853 scopus 로고    scopus 로고
    • Angiopoietin-2 and rat brain capillary remodeling during adaptation and deadaptation to prolonged mild hypoxia
    • P. Pichiule, and J.C. LaManna Angiopoietin-2 and rat brain capillary remodeling during adaptation and deadaptation to prolonged mild hypoxia J. Appl. Physiol. 93 2002 1131 1139 (Pubitemid 34919687)
    • (2002) Journal of Applied Physiology , vol.93 , Issue.3 , pp. 1131-1139
    • Pichiule, P.1    Lamanna, J.C.2
  • 39
    • 0037222832 scopus 로고    scopus 로고
    • Expression of angiopoietin-1 and -2 in the rat brain during chronic hypoxia and de-adaptation
    • P. Pichiule, and J.C. LaManna Expression of angiopoietin-1 and -2 in the rat brain during chronic hypoxia and de-adaptation Adv. Exp. Med. Biol. 510 2003 331 335 (Pubitemid 36312999)
    • (2003) Advances in Experimental Medicine and Biology , vol.510 , pp. 331-335
    • Pichiule, P.1    LaManna, J.C.2
  • 40
    • 0034703017 scopus 로고    scopus 로고
    • Age-dependent defect in vascular endothelial growth factor expression is associated with reduced hypoxia-inducible factor 1 activity
    • DOI 10.1074/jbc.M001029200
    • A. Rivard, L. Berthou-Soulie, N. Principe, M. Kearney, C. Curry, D. Branellec, G.L. Semenza, and J.M. Isner Age-dependent defect in vascular endothelial growth factor expression is associated with reduced hypoxia-inducible factor 1 activity J. Biol. Chem. 275 2000 29643 29647 (Pubitemid 32043844)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.38 , pp. 29643-29647
    • Rivard, A.1    Berthou-Soulie, L.2    Principe, N.3    Kearney, M.4    Curry, C.5    Branellec, D.6    Semenza, G.L.7    Isner, J.M.8
  • 41
    • 0033975589 scopus 로고    scopus 로고
    • Age-dependent increase in c-fos activity and cyclin A expression in vascular smooth muscle cells: A potential link between aging, smooth muscle cell proliferation and atherosclerosis
    • DOI 10.1016/S0008-6363(99)00385-5, PII S0008636399003855
    • A. Rivard, N. Principe, and V. Andres Age-dependent increase in c-fos activity and cyclin A expression in vascular smooth muscle cells. A potential link between aging, smooth muscle cell proliferation and atherosclerosis Cardiovasc. Res. 45 2000 1026 1034 (Pubitemid 30089665)
    • (2000) Cardiovascular Research , vol.45 , Issue.4 , pp. 1026-1034
    • Rivard, A.1    Principe, N.2    Andres, V.3
  • 42
    • 23644461909 scopus 로고    scopus 로고
    • Age-dependent increase of prolyl-4-hydroxylase domain (PHD) 3 expression in human and mouse heart
    • DOI 10.1007/s10522-005-7950-9
    • S. Rohrbach, A. Simm, R. Pregla, C. Franke, and D.M. Katschinski Age-dependent increase of prolyl-4-hydroxylase domain (PHD) 3 expression in human and mouse heart Biogerontology 6 2005 165 171 (Pubitemid 41131166)
    • (2005) Biogerontology , vol.6 , Issue.3 , pp. 165-171
    • Rohrbach, S.1    Simm, A.2    Pregla, R.3    Franke, C.4    Katschinski, D.M.5
  • 43
    • 0142166332 scopus 로고    scopus 로고
    • Targeting HIF-1 for cancer therapy
    • G.L. Semenza Targeting HIF-1 for cancer therapy Nat. Rev. Cancer 3 2003 721 732 (Pubitemid 37328811)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.10 , pp. 721-732
    • Semenza, G.L.1
  • 44
    • 8344237449 scopus 로고    scopus 로고
    • Hydroxylation of HIF-1: Oxygen sensing at the molecular level
    • G.L. Semenza Hydroxylation of HIF-1: oxygen sensing at the molecular level Physiol. (Bethesda) 19 2004 176 182 (Pubitemid 39481932)
    • (2004) Physiology , Issue.4 , pp. 176-182
    • Semenza, G.L.1
  • 45
    • 38449106142 scopus 로고    scopus 로고
    • Effect of aging on respiratory system physiology and immunology
    • G. Sharma, and J. Goodwin Effect of aging on respiratory system physiology and immunology Clin. Interv. Aging 1 2006 253 260
    • (2006) Clin. Interv. Aging , vol.1 , pp. 253-260
    • Sharma, G.1    Goodwin, J.2
  • 46
    • 77950900273 scopus 로고    scopus 로고
    • Regulation of hypoxia-inducible genes by PGC-1 alpha
    • J. Shoag, and Z. Arany Regulation of hypoxia-inducible genes by PGC-1 alpha Arterioscler. Thromb. Vasc. Biol. 30 2010 662 666
    • (2010) Arterioscler. Thromb. Vasc. Biol. , vol.30 , pp. 662-666
    • Shoag, J.1    Arany, Z.2
  • 47
    • 0039174315 scopus 로고    scopus 로고
    • Mitochondrial aconitase is a source of hydroxyl radical. An electron spin resonance investigation
    • DOI 10.1074/jbc.275.19.14064
    • J. Vasquez-Vivar, B. Kalyanaraman, and M.C. Kennedy Mitochondrial aconitase is a source of hydroxyl radical. An electron spin resonance investigation J. Biol. Chem. 275 2000 14064 14069 (Pubitemid 30339680)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.19 , pp. 14064-14069
    • Vasquez-Vivar, J.1    Kalyanaraman, B.2    Kennedy, M.C.3
  • 48
    • 34247893743 scopus 로고    scopus 로고
    • Cerebral angiogenic factors, angiogenesis, and physiological response to chronic hypoxia differ among four commonly used mouse strains
    • DOI 10.1152/japplphysiol.00909.2006
    • N.L. Ward, E. Moore, K. Noon, N. Spassil, E. Keenan, T.L. Ivanco, and J.C. LaManna Cerebral angiogenic factors, angiogenesis, and physiological response to chronic hypoxia differ among four commonly used mouse strains J. Appl. Physiol. 102 2007 1927 1935 (Pubitemid 46701964)
    • (2007) Journal of Applied Physiology , vol.102 , Issue.5 , pp. 1927-1935
    • Ward, N.L.1    Moore, E.2    Noon, K.3    Spassil, N.4    Keenan, E.5    Ivanco, T.L.6    LaManna, J.C.7
  • 49
    • 0016466780 scopus 로고
    • Membrane structure and its relation to haemolysis
    • R.I. Weed Membrane structure and its relation to haemolysis Clin. Haematol. 4 1975 3 28
    • (1975) Clin. Haematol. , vol.4 , pp. 3-28
    • Weed, R.I.1
  • 50
    • 0036320934 scopus 로고    scopus 로고
    • 2- regulated gene expression
    • DOI 10.1096/fj.01-0944rev
    • R.H. Wenger Cellular adaptation to hypoxia: O2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O2-regulated gene expression FASEB J. 16 2002 1151 1162 (Pubitemid 34815403)
    • (2002) FASEB Journal , vol.16 , Issue.10 , pp. 1151-1162
    • Wenger, R.H.1
  • 52
    • 0037838859 scopus 로고    scopus 로고
    • Ceramide-induced and age-associated increase in macrophage COX-2 expression is mediated through up-regulation of NF-κB activity
    • DOI 10.1074/jbc.M207470200
    • D. Wu, M. Marko, K. Claycombe, K.E. Paulson, and S.N. Meydani Ceramide-induced and age-associated increase in macrophage COX-2 expression is mediated through up-regulation of NF-kappa B activity J. Biol. Chem. 278 2003 10983 10992 (Pubitemid 36792646)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.13 , pp. 10983-10992
    • Dayong, W.1    Marko, M.2    Claycombe, K.3    Paulson, K.E.4    Meydani, S.N.5
  • 53
    • 41249098290 scopus 로고    scopus 로고
    • Aging up-regulates expression of inflammatory mediators in mouse adipose tissue
    • D. Wu, Z. Ren, M. Pae, W. Guo, X. Cui, A.H. Merrill, and S.N. Meydani Aging up-regulates expression of inflammatory mediators in mouse adipose tissue J. Immunol. 179 2007 4829 4839
    • (2007) J. Immunol. , vol.179 , pp. 4829-4839
    • Wu, D.1    Ren, Z.2    Pae, M.3    Guo, W.4    Cui, X.5    Merrill, A.H.6    Meydani, S.N.7
  • 54
    • 0030722269 scopus 로고    scopus 로고
    • Effect of chronic hypoxia on glucose transporters in heart and skeletal muscle of immature and adult rats
    • Y. Xia, J.B. Warshaw, and G.G. Haddad Effect of chronic hypoxia on glucose transporters in heart and skeletal muscle of immature and adult rats Am. J. Physiol. 273 1997 R1734 R1741
    • (1997) Am. J. Physiol. , vol.273
    • Xia, Y.1    Warshaw, J.B.2    Haddad, G.G.3
  • 55
    • 33646346397 scopus 로고    scopus 로고
    • Chronic hypoxia and the cerebral circulation
    • DOI 10.1152/japplphysiol.00940.2005
    • K. Xu, and J.C. LaManna Chronic hypoxia and the cerebral circulation J. Appl. Physiol. 100 2006 725 730 (Pubitemid 43671631)
    • (2006) Journal of Applied Physiology , vol.100 , Issue.2 , pp. 725-730
    • Xu, K.1    LaManna, J.C.2
  • 56
    • 5644261714 scopus 로고    scopus 로고
    • Renormalization of regional brain blood flow during prolonged mild hypoxic exposure in rats
    • DOI 10.1016/j.brainres.2004.08.046, PII S0006899304013381
    • K. Xu, M.A. Puchowicz, and J.C. LaManna Renormalization of regional brain blood flow during prolonged mild hypoxic exposure in rats Brain Res. 1027 2004 188 191 (Pubitemid 39371008)
    • (2004) Brain Research , vol.1027 , Issue.1-2 , pp. 188-191
    • Xu, K.1    Puchowicz, M.A.2    LaManna, J.C.3
  • 57
    • 77950594171 scopus 로고    scopus 로고
    • Decreased brainstem function following cardiac arrest and resuscitation in aged rat
    • K. Xu, M.A. Puchowicz, X. Sun, and J.C. LaManna Decreased brainstem function following cardiac arrest and resuscitation in aged rat Brain Res. 1328 2010 181 189
    • (2010) Brain Res. , vol.1328 , pp. 181-189
    • Xu, K.1    Puchowicz, M.A.2    Sun, X.3    Lamanna, J.C.4
  • 61
    • 0037291540 scopus 로고    scopus 로고
    • Normative aging of the respiratory system
    • DOI 10.1016/S0749-0690(02)00063-0, PII S0749069002000630
    • J. Zeleznik Normative aging of the respiratory system Clin. Geriatr. Med. 19 2003 1 18 (Pubitemid 36020192)
    • (2003) Clinics in Geriatric Medicine , vol.19 , Issue.1 , pp. 1-18
    • Zeleznik, J.1


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