Neuroprotection of erythropoietin and methylprednisolone against spinal cord ischemia-reperfusion injury

Journal of Huazhong University of Science and Technology - Medical Science

Volumn 31, Issue 5, 2011, Pages 652-656

  Xiong, Min ^a,b   Chen, Sen ^b   Yu, Hualong ^b   Liu, Zhigang ^b   Zeng, Yun ^b   Li, Feng ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b HUBEI UNIVERSITY OF MEDICINE   (China)

Author keywords

erythropoietin; ischemia reperfusion injury; methylprednisolone; neuroprotection; spinal cord

Indexed keywords

ERYTHROPOIETIN; METHYLPREDNISOLONE; NEUROPROTECTIVE AGENT;

ADULT; AGED; ARTICLE; DECOMPRESSION SURGERY; FEMALE; HUMAN; MALE; MIDDLE AGED; REPERFUSION INJURY; RETROSPECTIVE STUDY; SPINAL CORD; SPINAL CORD COMPRESSION; SPINAL CORD ISCHEMIA;

ADULT; AGED; DECOMPRESSION, SURGICAL; ERYTHROPOIETIN; FEMALE; HUMANS; MALE; METHYLPREDNISOLONE; MIDDLE AGED; NEUROPROTECTIVE AGENTS; REPERFUSION INJURY; RETROSPECTIVE STUDIES; SPINAL CORD; SPINAL CORD COMPRESSION; SPINAL CORD ISCHEMIA;

EID: 80455137112     PISSN: 16720733     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11596-011-0576-z     Document Type: Article

References (17)

1. C. Dame S. Juul R.D. Christensen 2001 The biology of erythropoietin in the central nervous system and its neurotrophic and neuroprotective potential Biol Neonate 79 3-4 228 235 11275657 1:CAS:528:DC%2BD3MXjsVWgu7o%3D (Pubitemid 32247092)
2. R. Liu A. Suzuki Z. Guo, et al. 2006 Intrinsic and extrinsic ery thropoietin enhances neuroprotection against ischemia and reperfusion injury in vitro J Neurochem 96 4 1101 1110 16417583 10.1111/j.1471-4159.2005.03597.x 1:CAS:528:DC%2BD28XivFWjs74%3D
3. M. Capaul H. Zollinger N. Satz, et al. 1994 Analyses of 94 consecutive spinal cord injury patients using ASIA definition and modified Frankel score classification Paraplegia 32 9 583 587 7997337 10.1038/sc.1994.92 1:STN:280:DyaK2M%2FovFyqsg%3D%3D (Pubitemid 24280647)
4. W.S. EI Masry M. Tsubo S. Katoh, et al. 1996 Validation of the American Spinal Injury Association (ASIA) motor score and the National Acute Spinal Cord Injury Study (NASCIS) motor score Spine 21 5 614 619 10.1097/00007632-199603010- 00015 (Pubitemid 26077802)
5. G. Grasso A. Sfacteria F. Meli, et al. 2007 The role of erythropoietin in neuroprotection: therapeutic perspectives Drug News Perspect 20 5 315 320 17878959 10.1358/dnp.2007.20.5.1120219 1:CAS:528:DC%2BD2sXhtVKrtbjK (Pubitemid 47345223)
6. O. Okutan I. Solaroglu E. Beskonakli, et al. 2007 Recombinant human erythropoietin decreases myeloperoxidase and caspase-3 activity and improves early functional results after spinal cord injury in rats J Clin Neurosci 14 4 364 368 17236773 10.1016/j.jocn.2006.01.022 1:CAS:528:DC%2BD2sXisVWitb8%3D
7. B.H. Choi Y. Ha C.H. Ahn, et al. 2007 A hypoxia-inducible gene expression system using erythropoietin 3′ untranslated region for the gene therapy of rat spinal cord injury Neurosci Lett 412 2 118 122 17178192 10.1016/j.neulet.2006.11.015 1:CAS:528:DC%2BD2sXltVWnsw%3D%3D (Pubitemid 46074362)
8. L. Vitellaro-Zuccarello S. Mazzetti L. Madaschi, et al. 2007 Erythropoietin-mediated preservation of the white matter in rat spinal cord injury Neuroscience 144 3 865 877 17141961 10.1016/j.neuroscience.2006.10.023 1:CAS:528:DC%2BD2sXhsFKrtw%3D%3D (Pubitemid 46013988)
9. C. Mann J.H. Lee J. Liu, et al. 2008 Delayed treatment of spinal cord injury with erythropoietin or darbepoetin-a lack of neuroprotective efficacy in a contusion model of cord injury Exp Neurol 211 1 34 40 18313052 10.1016/j.expneurol.2007.12.013 1:CAS:528:DC%2BD1cXlsF2qtbo%3D
10. L. Vitellaro-Zuccarello S. Mazzetti L. Madaschi, et al. 2008 Chronic erythropoietin-mediated effects on the expression of astrocyte markers in a rat model of contusive spinal cord injury Neuroscience 151 2 452 466 18065151 10.1016/j.neuroscience.2007.11.004 1:CAS:528:DC%2BD1cXls1Ggug%3D%3D
11. X.Q. Fang M. Fang S.W. Fan, et al. 2009 Protection of erythropoietin on experimental spinal cord injury by reducing the expression of thrombospondin-1 and transforming growth factor-beta Chin Med J (Engl) 122 14 1631 1635
12. G.K. Matis T.A. Birbilis 2009 Erythropoietin in spinal cord injury Eur Spine J 18 3 314 323 19030901 10.1007/s00586-008-0829-0
13. V.A. Kontogeorgakos S. Voulgaris A.V. Korompilias, et al. 2009 The efficacy of erythropoietin on acute spinal cord injury. An experimental study on a rat model Arch Orthop Trauma Surg 129 2 189 194 18309506 10.1007/s00402-008- 0594-x
14. A. Gorio L. Madaschi B. Di Stefano, et al. 2005 Methylprednisolone neutralizes the beneficial effects of erythropoietin in experimental spinal cord injury Proc Natl Acad Sci USA 102 45 16 379 16 384 10.1073/pnas.0508479102 1:CAS:528:DC%2BD2MXht1CgurvK (Pubitemid 41688922)
15. M.S. Kim Y.K. Seo H.J. Park, et al. 2010 The neuroprotective effect of recombinant human erythropoietin via an antiapoptotic mechanism on hypoxic-ischemic brain injury in neonatal rats Korean J Pediatr 53 10 898 908 21189961 10.3345/kjp.2010.53.10.898 1:CAS:528:DC%2BC3MXkvVaqtLw%3D
16. K. Maiese Z.Z. Chong J. Hou, et al. 2009 New strategies for Alzheimers disease and cognitive impairment Oxid Med Cell Longev 2 5 279 289 20716915 10.4161/oxim.2.5.9990
17. M. Xiong S. Chen Y. Zeng, et al. 2011 The effect of erythropoietin on the mobility of bone marrow mesenchymal stem cell to the sites of injured spinal cord Chin J Exp Surg (Chinese) 28 4 618 520 1:CAS:528:DC%2BC3MXpt1ajs74%3D