Hyperoxia causes angiopoietin 2-mediated acute lung injury and necrotic cell death

Nature Medicine

Volumn 12, Issue 11, 2006, Pages 1286-1293

  Bhandari, Vineet ^a   Choo Wing, Rayman ^a   Lee, Chun G ^a   Zhu, Zhou ^a   Nedrelow, Jonathan H ^a   Chupp, Geoffrey L ^a   Zhang, Xucher ^a   Matthay, Michael A ^b   Ware, Lorraine B ^c   Homer, Robert J ^a,d   Lee, Patty J ^a   Geick, Anke ^e   De Fougerolles, Antonin R ^e   Elias, Jack A ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^d VA CONNECTICUT HEALTHCARE SYSTEM   (United States)

^e ALNYLAM PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOPOIETIN 2; CASPASE; SMALL INTERFERING RNA;

ACUTE LUNG INJURY; ADULT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CONTROLLED STUDY; ENZYME ACTIVATION; EPITHELIUM CELL; HUMAN; HYPEROXIA; IN VITRO STUDY; IN VIVO STUDY; LUNG; LUNG ALVEOLUS EPITHELIUM; LUNG DYSPLASIA; LUNG EDEMA; MORTALITY; MOUSE; NEWBORN; NONHUMAN; PLASMA; PNEUMONIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRACHEA; WILD TYPE;

ANGIOPOIETIN-2; ANIMALS; CELL DEATH; HYPEROXIA; MICE; PULMONARY EDEMA; RNA, MESSENGER; RNA, SMALL INTERFERING;

EID: 33750699301     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm1494     Document Type: Article

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