Oxygen resuscitation after hypoxia ischemia stimulates prostaglandin pathway in rat cortex

International Journal of Developmental Neuroscience

Volumn 29, Issue 6, 2011, Pages 639-644

  Perez Polo, J Regino ^a   Reilly, Conor B ^a   Rea, Harriet C ^a  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

Cyclooxygenase; Hyperoxia; Hypoxia ischemia; Nitric oxide synthase; Perinatal ischemia

Indexed keywords

ARACHIDONATE 5 LIPOXYGENASE; CYCLOOXYGENASE 2; INDUCIBLE NITRIC OXIDE SYNTHASE; LEUKOTRIENE; OXYGEN; PROSTAGLANDIN; PROSTAGLANDIN E2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; FEMALE; HYPOXIC ISCHEMIC ENCEPHALOPATHY; NITROSYLATION; NONHUMAN; PERINATAL CARE; PRIORITY JOURNAL; RAT; RESUSCITATION;

ANIMALS; CELL DEATH; CYCLOOXYGENASE 2; FEMALE; HUMANS; HYPOXIA-ISCHEMIA, BRAIN; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS; OXYGEN; PREGNANCY; PROSTAGLANDINS; RANDOM ALLOCATION; RATS; RATS, WISTAR;

RATTUS; RODENTIA;

EID: 80052410726     PISSN: 07365748     EISSN: 1873474X     Source Type: Journal    
DOI: 10.1016/j.ijdevneu.2011.03.009     Document Type: Article

References (65)

1. Allen M.C. Neurodevelopmental outcomes of preterm infants. Curr. Opin. Neurol. 2008, 218:123-128.
2. Almeida A., Bolanos J.P. A transient inhibition of mitochondrial ATP synthesis by nitric oxide synthase activation triggered apoptosis in primary cortical neurons. J. Neurochem. 2001, 77:676-690.
3. Back S.A., Han B.H., Luo N.L., Chrichton C.A., Tam J., Xanthoudakis S., Arvin K.L., Holtzman D.M. Selective vulnerability of late oligodendrocyte progenitors to hypoxia-ischemia. J. Neurosci. 2002, 22:455-463.
4. Bagenholm R., Hagberg H., Kjellmer I. Impact of reoxygenation with oxygen and air on the extent of the brain damage after hypoxia-ischaemia in neonatal rats. Acta Paediatr. 1996, 85:1228-1231.
5. Bissinger R.L., Ohning B.L. Neonatal Resuscitation http://www.emedicine.com/ped/topic2598.htm.
6. Bockhorst K.H., Narayana P.A., Dulin J., Liu R., Rea H.C., Wosik H.K., Perez-Polo J.R. Normobaric hyperoximia increases hypoxia-induced cerebral injury: DTI study in rats. J. Neurosci. Res. 2010, 88:1146-1156. (PMCID: PMC Journal - In Process).
7. Boichot C., Walker P.M., Durand C., Grimaldi M., Chapuis S., Gouyon J.B., Brunotte F. Term neonate prognoses after perinatal asphyxia: contributions of Mr imaging, Mr spectroscopy relaxation times, and apparent diffusion coefficients. Radiology 2006, 239:839-848.
8. Bolanos J.P., Almeida A. Roles of nitric oxide in brain hypoxia-ischemia. Biochim. Biophys. Acta 1999, 1411:415-436.
9. Bonmann E., Suschek C., Spranger M., Kolb-Bachofen V. The dominant role of exogenous or endogenous interleukin-1 beta on expression and activity of inducible nitric oxide synthase in rat microvascular brain endothelial cells. Neurosci. Lett. 1997, 230:109-112.
10. Brown G.C., Bal-Price A. Inflammatory neurodegeneration mediated by nitric oxide, glutamate, and mitochondria. Mol. Neurobiol. 2003, 27:325-355.
11. Cai Z., Xiao F., Lee B., Paul I.A., Rhodes P.G. Prenatal hypoxia-ischemia alters expression and activity of nitric oxide synthase in the young rat brain and causes learning deficits. Brain Res. Bull. 1999, 49:359-365.
12. deMenezes M.S., Shaw D.W. Hypoxic-ischemic Brain Injury in the Newborn http://www.emedicine.com/neuro/topic696.htm.
13. Dunn S.L., Young E.A., Hall M.D., McNulty S. Activation of astrocyte intracellular signaling pathways by interleukin-1 in rat primary striatal cultures. Glia 2002, 37:31-42.
14. Fabian R.H., Perez-Polo J.R., Kent T.A. Perivascular nitric oxide and superoxide in neonatal cerebral hypoxia-ischemia. Am. J. Physiol. 2008, 295:H1809-H1814. (PMCID: PMC2593505).
15. Ferrari D.C., Nesic-Taylor O.B., Perez-Polo J.R. Oxygen resuscitation does not ameliorate neonatal hypoxia/ischemia-induced cerebral edema. J. Neurosci. Res. 2010, 88:2056-2065. (PMCID: PMC Journal - In Process).
16. Ferrari D.C., Nesic O., Perez-Polo J.R. Perspectives on neonatal hypoxia/ischemia-induced edema formation. Neurochem. Res. 2010, 35:1957-1965. 10.1007/s11064-010-0308-y.
17. Flower R.J. The development of COX2 inhibitors. Nat. Drug Discov. 2003, 2:179.
18. Gill M., Bockhorst K.H., Narayana P.A., Perez-Polo J.R. Bax shuttling after neonatal hypoxia-ischemia: hyperoxia effects. J. Neurosci. Res. 2008, 86(December (16)):3584-3604. (PMCID: PMC2585158).
19. Gill M., Perez-Polo J.R. Bax shuttling after rotenone treatment of neuronal primary cultures: effects on cell death phenotypes. J. Neurosci. Res. 2009, 87:2047-2065. (PMCID: PMC Journal - In Process).
20. Hains B.C., Yucra J.A., Hulsebosch C.E. Reduction of pathological and behavioral deficits following spinal cord contusion injury with the selective cycloooxygenase-2 inhibitor NS-398. J. Neurotrauma 2001, 18:409-423.
21. Hamada Y., Hayakawa T., Hattori H., Mikawa H. Inhibitor of nitric oxide synthesis reduces hypoxic-ischemic brain damage in the neonatal rat. Pediatr. Res. 1994, 35:10-14.
22. Hara H., Fink K., Endres M., Friedlander R.M., Gagliardini V., Yuan J., Moskowitz M.A. Attenuation of transient focal cerebral ischemic injury in transgenic mice expressing a mutant ICE inhibitory protein. J. Cereb. Blood Flow Metab. 1997, 17:370-375.
23. Hara H., Huang P.L., Panahian N., Fishman M.C., Moskowitz M.A. Reduced brain edema and infarction volume in mice lacking the neuronal isoform of nitric oxide synthase after transient MCA occlusion. J. Cereb. Blood Flow Metab. 1996, 16:605-611.
24. Hedtjarn M., Leverin A.L., Eriksson K., Blomgren K., Mallard C., Hagberg H. Interleukin-18 involvement in hypoxic-ischemic brain injury. J. Neurosci. 2002, 22:5910-5919.
25. Heron M., Hoyert D.L., Murphy S.L., Xu J., Kochanek K.D., et al. Deaths: Final data for 2006. National Vital Statistics Reports, 57 (14) 2009, U.S. Centers for Disease Control and Prevention, Atlanta.
26. Hu X., Qiu J., Grafe M.R., Rea H.C., Rassin D.K., Perez-Polo J.R. Bcl-2 family members make different contributions to cell death in hypoxia and/or hyperoxia in rat cerebral cortex. Int. J. Dev. Neurosci. 2003, 21:371-378.
27. Hu X., Nesic-Taylor O., Qiu J., Rea H.C., Fabian R., Rassin D.K., Perez-Polo J.R. Activation of nuclear factor-κB signaling pathway by interleukin-1 after hypoxia/ischemia in neonatal rat hippocampus and cortex. J. Neurochem. 2005, 93:26-37.
28. Iadecola C., Zhang F.Y., Xu S., Casey R., Ross M.E. Inducible nitric oxide synthase gene expression in brain following cerebral ischemia. J. Cereb. Blood Flow Metab. 1995, 15:378-384.
29. Ikeno S., Nagata N., Yoshida S., Takahashi H., Kigawa J., Terakawa N. Immature brain injury via peroxynitrite production induced by inducible nitric oxide synthase after hypoxia-ischemia in rats. J. Obstet. Gynaecol. Res. 2000, 26:227-234.
30. Kaufmann W.E., Worley P.F., Pegg J., Bremer M., Isakson P. COX-2, a synaptically induced enzyme, is expressed by excitatory neurons at postsynaptic sites in rat cerebral cortex. Proc. Natl. Acad. Sci. U.S.A. 1996, 93:2317-2321.
31. Kim S.F., Huri D.A., Snyder S.H. Inducible nitric oxide synthase binds S-nitrosylates, and activates cyclooxygenase-2. Science 2005, 310:1966-1970.
32. Kutzsche S., Kirkeby O.J., Rise I.R., Saugstad O.D. Effects of hypoxia and reoxygenation with 21% and 100%-oxygen on cerebral nitric oxide concentration and microcirculation in newborn piglets. Biol. Neonate 1999, 76:153-167.
33. Loepke A.W., McCann J.C., Kurth C.D., McAuliffe J.J. The physiologic effects of isoflurane anesthesia in neonatal mice. Anesth. Analg. 2006, 102:75-80.
34. Lubec B., Kozlov A.V., Krapfenbauer K., Berger A., Hoeger H., Herrera-Marschitz M., Nohl H., Koeck T., Lubec G. Nitric oxide and nitric oxide synthase in the early phase of perinatal asphyxia of the rat. Neuroscience 1999, 93:1017-1023.
35. Lundstrom K.E., Pryds O., Greisen G. Oxygen at birth and prolonged cerebral vasoconstriction in preterm infants. Arch. Dis. Child. Fetal Neonatal Ed. 1995, 73:F81-F86.
36. Martin S.S., Perez-Polo J.R., Noppens K.M., Grafe M.R. Biphasic changes in the levels of poly(ADP-ribose) polymerase-1 and caspase 3 in the immature brain following hypoxia-ischemia. Int. J. Dev. Neurosci. 2005, 23:673-686.
37. Mizushima H., Zhou C.J., Dohi K., Horai R., Asano M., Iwakura Y., Hirabayashi T., Arata S., Nakajo S., Takaki A., Ohtaki H., Shioda S. Reduced postischemic apoptosis in the hippocampus of mice deficient in interleukin-1. J. Comp. Neurol. 2002, 448:203-216.
38. Morita I., Schindler M., Regier M.K., Otto J.C., Hori T., DeWitt D.L., et al. Different intracellular locations for prostaglandin endoperoxidase H synthase-1 and -2. J. Biol. Chem. 1995, 270:10902-10908.
39. Moss W., Darmstadt G.L., Marsh D.R., Black R.E., Santosham M. Research priorities for the reduction of perinatal and neonatal morbidity and mortality in developing country communities. J. Perinatol. 2002, 484-495.
40. Munkeby B.H., Borke W.B., Bjornland K., Sikkeland L.I., Borge G.I., Halvorsen B., Saugstad O.D. Resuscitation with 100% O2 increases cerebral injury in hypoxemic piglets. Pediatr. Res. 2004, 56:783-790.
41. Newton R., Kuitert L.M., Bergmannn M., et al. Evidence for involvement of NF-κB in the transcriptional control of COX-2 gene expression by IL-1β. Biochem. Biophys. Res. Commun. 1997, 237:28-32.
42. Niwa M., Inao S., Takayasu M., et al. Time course of expression of three nitric oxide synthase isoforms after transient middle cerebral artery occlusion in rats. Neurol. Med. Chir. (Tokyo) 2001, 41:63-73.
43. Odding E., Roebroeck M.E., Stam H.J. The epidemiology of cerebral palsy: incidence, impairments and risk factors. Disabil. Rehabil. 2006, 28:183-191.
44. Platt M.J., Cans C., Johnson A., Surman G., Topp M., Torrioli M.G., Krageloh-Mann I. Trends in cerebral palsy among infants of very low birthweight (<1500g) or born prematurely (<32 weeks) in 16 European centres: a database study. Lancet 2007, 369:43-50.
45. Qiu J.-X., Grafe M.R., Schmura S.M., Glasgow J., Kent T.A., Rassin D.K., Perez-Polo.J.R. Differential NF-κB regulation of bcl-x gene expression in Hippocampus and basal forebrain in response to hypoxia. J. Neurosci. Res. 2001, 64:223-234.
46. Qiu J., Hu X., Nesic O., Grafe M.R., Rassin D.K., Perez-Polo J.R. Effects of NF-κB Oligonucleotide " Decoys" on gene expression in p7 rat hippocampus after hypoxia/ischemia. J. Neurosci. Res. 2004, 77:108-118.
47. Raju T.N.K. Hypoxic Ischemic Encephalopathy http://www.emedicine.com/ped/topic149.htm.
48. Resnick D.K., Graham S.H., Dixon C.E., Marion D.W. Role of cyclooxygenase 2 in acute spinal cord injury. J. Neurotrauma 1998, 15:1005-1013.
49. Rice J.E., Vannucci R.C., Brieley J.B. The influence of immaturity on hypoxic-ischemic brain damage in the rat. Ann. Neurol. 1981, 9:131-141.
50. Rodrigo J., Alonso D., Fernandez A.P., Serrano J., Richart A., Lopez J.C., Santacana M., Martinez-Murillo R., Bentura M.L., Ghiglione M., Uttenthal L.O. Neuronal and inducible nitric oxide synthase expression and protein nitration in rat cerebellum alter oxygen and glucose deprivation. Brain Res. 2001, 909:20-45.
51. Saugstad O.D. Oxidative stress in the newborn - a 30-year perspective. Biol. Neonate 2005, 88:228-3631.
52. Serou M.J., DeCoster M.A., Bazan N.G. Interleukin-1 beta activates expression of cyclooxygenase-2 and inducible nitric oxide synthase in primary hippocampal neuronal culture: platelet-activating factor as a preferential mediator of cyclooxygenase-2 expression. J. Neurosci. Res. 1999, 58:593-598.
53. Shimabuku R., Ota A., Pereyra S., Veliz B., Paz E., Nakachi G., More M., Oliveros M. Hyperoxia with 100% oxygen following hypoxia-ischemia increases brain damage in newborn rats. Biol. Neonat. 2005, 88:168-171.
54. Smith W.L., DeWitt D.L., Garavito R.M. Cyclooxygenases: structural, cellular and molecular biology. Annu. Rev. Biochem. 2002, 69:145-182.
55. Spencer A.G., Thuresson E., Otto J.C., Song I., Smith T., DeWitt D.L., et al. The membrane binding domains of prostaglandin endoperoxidase H synthases 1 and 2. Peptide mapping and mutational analysis. J. Biol. Chem. 1999, 274:32936-32942.
56. Szaflarski J., Burtrum D., Silverstein F.S. Cerebral hypoxia-ischemia stimulates cytokine gene expression in perinatal rats. Stroke 1995, 26:1093-1100.
57. Teng X., Zhang H., Snead C., Catravas J.D. Molecular mechanisms of iNOS induction by IL-1 beta and IFN-gamma in rat aortic smooth muscle cells. Am. J. Physiol. Cell Physiol. 2002, 282:C144-C152.
58. Touzani O., Boutin H., Chuquet J., Rothwell N. Potential mechanisms of interleukin-1 involvement in cerebral ischaemia. J. Neuroimmunol. 1999, 100:203-215.
59. Trifiletti R.R. Neuroprotective effects of NG-nitro-l-arginine in focal stroke in the 7-day old rat. Eur. J. Pharmacol. 1992, 218:197-198.
60. Turini M.E., DuBois R.N. Cyclooxygenase 2: a therapeutic target. Annu. Rev. Med. 2002, 53:35-57.
61. Van den Tweel E.R., Nijboer C., Kavelaars A., Heijnen C.J., Groenendaal F., van Bel F. Expression of nitric oxide synthase isoforms and nitrotyrosine formation after hypoxia-ischemia in the neonatal rat brain. J. Neuroimmunol. 2008, 167:64-71.
62. Vannucci R.C., Connor J.R., Mauger D.T., Palmer C., Smith M.B., Towfighi J., Vannucci S.J. Rat model of perinatal hypoxic-ischemic brain damage. J. Neurosci. Res. 1999, 55:158-163.
63. Yamagata K., Andreasson K.I., Kaufmann W.E., Barnes C.A., Worley P.F. Expression of a mitogen-inducible cyclooxygenase in brain neurons: regulation by synaptic activity and glucocorticoids. Neuron 1993, 11:371-386.
64. Zanelli S., Stanley D.P., Kaufman D. Hypoxic-ischemic Encephalopathy http://emedicine.medscape.com/article/973501-overview.
65. Zhang Z.G., Chopp M., Zaloga C., Pollock J.S., Forstermann U. Cerebral endothelial nitric oxide synthase expression after focal cerebral ischemia in rats. Stroke 1993, 24:2016-2022.