Dopamine induces apoptosis in APPswe-expressing Neuro2A cells following Pepstatin-sensitive proteolysis of APP in acid compartments

Brain Research

Volumn 1471, Issue , 2012, Pages 102-117

  Cagnin, Monica ^a   Ozzano, Matteo ^a   Bellio, Natascia ^a   Fiorentino, Ilaria ^a   Follo, Carlo ^a   Isidoro, Ciro ^a  

^a UNIVERSITY OF EASTERN PIEDMONT   (Italy)

Author keywords

Alzheimer's disease; Chloroquine; Lysosome; Parkinson's disease; Pepstatin A

Indexed keywords

AMYLOID PRECURSOR PROTEIN; DOPAMINE; GAMMA SECRETASE INHIBITOR; PEPSTATIN; PHORBOL ESTER;

ALZHEIMER DISEASE; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL DEATH; CONTROLLED STUDY; CYTOTOXICITY; ENDOCYTOSIS; ENDOSOME; HUMAN; HUMAN CELL; LYSOSOME; NERVE CELL; NERVE DEGENERATION; NEUROBLASTOMA CELL; PARKINSONISM; PRIORITY JOURNAL; PROTEIN DEGRADATION;

AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CARBAMATES; CATHEPSIN D; CELL LINE, TUMOR; CHLOROQUINE; DIPEPTIDES; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOCYTOSIS; GENE EXPRESSION REGULATION, NEOPLASTIC; GREEN FLUORESCENT PROTEINS; HUMANS; IN SITU NICK-END LABELING; LYSOSOMES; MICE; MITOCHONDRIAL MEMBRANES; NEUROBLASTOMA; PEPSTATINS; PHORBOL ESTERS; PROTEASE INHIBITORS; PROTEIN BIOSYNTHESIS; PROTEOLYSIS; RNA, SMALL INTERFERING; TRANSFECTION;

PARKINSONIA;

EID: 84864684593     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2012.06.025     Document Type: Article

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