Cathepsin D displays in vitro β-secretase-like specificity

Brain Research

Volumn 750, Issue 1-2, 1997, Pages 11-19

  Chevallier, Nathalie ^a   Vizzavona, Jean ^a   Marambaud, Philippe ^a   Baur, Claus Peter ^b   Spillantini, Maria ^b   Fulcrand, Pierre ^a   Martinez, Jean ^a   Goedert, Michel ^b   Vincent, Jean Pierre ^a   Checler, Frédéric ^a  

^a CNRS   (France)

^b MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

secretase; acidic protease; Alzheimer's disease; cathepsin D; FCA18 antibody; recombinant APP; Swedish mutation

Indexed keywords

ACIDIC PROTEINASE; AMYLOID BETA PROTEIN; BETA SECRETASE; CATHEPSIN D; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN TISSUE; CELL CULTURE; CELL STRAIN; CONTROLLED STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; MUTATION; NONHUMAN; PRIORITY JOURNAL; RAT;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ENDOPEPTIDASES; ASTROCYTES; BRAIN; CATHEPSIN D; CELL LINE; ENDOPEPTIDASES; HUMANS; KINETICS; MICE; MUTAGENESIS, SITE-DIRECTED; OLIGOPEPTIDES; PC12 CELLS; PEPSTATINS; POINT MUTATION; PROTEASE INHIBITORS; RATS; RECOMBINANT PROTEINS; SPODOPTERA; SUBSTRATE SPECIFICITY; TRANSFECTION;

EID: 0031043282     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(96)01330-3     Document Type: Article

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