Regulation of myo-inositol homeostasis in differentiated human NT2-N neurons

Neurochemical Research

Volumn 25, Issue 5, 2000, Pages 561-566

  Novak, James E ^a,b   Agranoff, Bernard W ^a,b   Fisher, Stephen K ^a,b,c  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Calcium; Inositol efflux; Inositol uptake; Neuron; Protein kinase C; Second messenger

Indexed keywords

INOSITOL;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; HUMAN; HUMAN CELL; NERVE CELL DIFFERENTIATION; PRIORITY JOURNAL; SECOND MESSENGER;

4,4'-DIISOTHIOCYANOSTILBENE-2,2'-DISULFONIC ACID; BIOLOGICAL TRANSPORT; CALCIUM; CELL DIFFERENTIATION; CYCLIC GMP; ENZYME ACTIVATION; HUMANS; HYPOTONIC SOLUTIONS; INOSITOL; IONOMYCIN; LITHIUM; NEURONS; OXOTREMORINE; PROTEIN KINASE C; SECOND MESSENGER SYSTEMS; SIGNAL TRANSDUCTION; TERATOCARCINOMA; TETRADECANOYLPHORBOL ACETATE; TRITIUM; TUMOR CELLS, CULTURED;

EID: 0033932696     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1007538431486     Document Type: Article

References (34)

1. Pasantes-Morales, H., Alavez, S., Sánchez-Olea, R., and Morán, J. 1993. Contribution of organic and inorganic osmolytes to volume regulation in rat brain cells in culture. Neurochem. Res. 18: 445-452.
2. Prockop, L. D. 1971. Hyperglycemia, polyol accumulation, and increased intracranial pressure. Arch. Neurol. 25:126-140.
3. Lien, Y-H. H., Shapiro, J. I., and Chan, L. 1990. Effects of hypernatremia on organic brain osmoles. J. Clin. Invest. 85:1427-1435.
4. Lee, J. H., Arcinue, E., and Ross, B. D. 1994. Brief report: organic osmolytes in the brain of an infant with hypernatremia. N. Engl. J. Med. 331:439-442.
5. Jackson, P. S. and Madsen, J. R. 1997. Identification of the volume-sensitive organic osmolyte/anion channel in human glial cells. Pediatr. Neurosurg. 27:286-291.
6. Gullans, S. R. and Verbalis, J. G. 1993. Control of brain volume during hyperosmolar and hypoosmolar conditions. Annu. Rev. Med. 44:289-301.
7. Nonaka, M., Yoshimine, T., Kohmura, E., Wakayama, A., Yamashita, T., and Hayakawa, T. 1998. Changes in brain organic osmolytes in experimental cerebral ischemia. J. Neurol. Sci. 157:25-30.
8. Jackson, P. S., Morrison, R., and Strange, K. 1994. The volume-sensitive organic osmolyte-anion channel VSOAC is regulated by nonhydrolytic ATP binding. Am. J. Physiol. 267:C1203-C1209.
9. - channel blockers of the volume-activated, diffusional mechanism of inositol transport in primary astrocytes in culture. Neurochem. Res. 20:895-900.
10. Strange, K., Morrison, R., Shrode, L., and Putnam, R. 1993. Mechanism and regulation of swelling-activated inositol efflux in brain glial cells. Am. J. Physiol. 265:C244-C256.
11. 2+ modulation of myo-inositol transport in cultured retinal pigment epithelial cells. Am. J. Physiol. 273: C671-C678.
12. Reeves, R. E. and Cammarata, P. R. 1996. Osmoregulatory alterations in myo-inositol uptake by bovine lens epithelial cells. Invest. Ophthalmol. Vis. Sci. 37:619-629.
13. Ruhfus, B. and Kinne, R. K. H. 1996. Hypotonicity-activated efflux of taurine and myo-inositol in rat inner medullary collecting duct cells: evidence for a major common pathway. Kidney Blood Press. Res. 19:317-324.
14. Ruhfus, B., Tinel, H., and Kinne, R. K. H. 1996. Role of G-proteins in the regulation of organic osmolyte efflux from isolated rat renal inner medullary collecting duct cells. Eur. J. Physiol. 433:35-41.
15. Preston, A. S., Yamauchi, A., Kwon, H. M., and Handler, J. S. 1995. Activators of protein kinase A and of protein kinase C inhibit MDCK cell myo-inositol and betaine uptake. J. Am. Soc. Nephrol. 6:1559-1564.
16. Bagnasco, S. M., Montrose, M. H., and Handler, J. S. 1993. Role of calcium in organic osmolyte efflux when MDCK cells are shifted from hypertonic to isotonic medium. Am. J. Physiol. 264:C1165-C1170.
17. Andrews, P. W. 1984. Retinoic acid induces neuronal differentiation of a cloned human embryonal carcinoma cell line in vitro. Dev. Biol. 103:285-293.
18. Andrews, P. W., Damjanov, I., Simon, D., Banting, G. S., Carlin, C., Dracopoli, N. C., and Føgh, J. 1984. Pluripotent embryonal carcinoma clones derived from the human teratocarcinoma cell line Tera-2. Lab. Invest. 50:147-162.
19. Pleasure, S. J., Page, C., and Lee, V. M.-Y. 1992. Pure, postmitotic, polarized human neurons derived from NTera 2 cells provide a system for expressing exogenous proteins in terminally differentiated neurons. J. Neurosci. 12:1802-1815.
20. Lee, V. M.-Y. and Andrews, P. W. 1986. Differentiation of NTERA-2 clonal human embryonal carcinoma cells into neurons involves the induction of all three neurofilament proteins. J. Neurosci. 6:514-521.
21. Hartley, R. S., Margulis, M., Fishman, P. S., Lee, V. M.-Y., and Tang, C.-M. 1999. Functional synapses are formed between human NTera2 (NT2N, hNT) neurons grown on astrocytes. J. Comp. Neurol. 407:1-10.
22. Novak, J. E., Turner, R. S., Agranoff, B. W., and Fisher, S. K. 1999. Differentiated human NT2-N neurons possess a high intracellular content of myo-inositol. J. Neurochem. 72:1431-1440.
23. Batty, I. H., Michie, A., Fennel, M., and Downes, C. P. 1993. The characteristics, capacity and receptor regulation of inositol uptake in 1321N1 astrocytoma cells. Biochem. J. 294:49-55.
24. 2+ influx, and protein kinase C activation in sustained cellular responses. Endocr. Rev. 16:649-681.
25. +-inositol cotransporter activity and mRNA levels in brain glial cells. Am. J. Physiol. 263:C1282-C1288.
26. Wiese, T. J., Dunlap, J. A., Conner, C. E., Grzybowski, J. A., Lowe, W. L., Jr., and Yorek, M. A. 1996. Osmotic regulation of Na-myo-inositol cotransporter mRNA level and activity in endothelial and neural cells. Am. J. Physiol. 270:C990-C997.
27. Wolfson, M., Hertz, E., Belmaker, R. H., and Hertz, L. 1998. Chronic treatment with lithium and pretreatment with excess inositol reduce inositol pool size in astrocytes by different mechanisms. Brain Res. 787:34-40.
28. Goldstein, L. and Davis, E. M. 1994. Taurine, betaine, and inositol share a volume-sensitive transporter in skate erythrocyte cell membrane. Am. J. Physiol. 267:R426-R431.
29. Bender, A. S. and Norenberg, M. D. 1994. Calcium dependence of hypoosmotically induced potassium release in cultured astrocytes. J. Neurosci. 14:4237-4243.
30. Jackson, P. S. and Strange, K. 1993. Volume-sensitive anion channels mediate swelling-activated inositol and taurine efflux. Am. J. Physiol. 265:C1489-C1500.
31. Liedtke, C. M. 1995. The role of protein kinase C in α-adrenergic regulation of NaCl(K) cotransport in human airway epithelial cells. Am. J. Physiol. 268:L414-L423.
32. Cln mRNA in cultured bovine lens epithelial cells: response to changes in cell volume. Curr. Eye Res. 17:861-869.
33. Cln forms highly cation-selective channels when reconstituted into artificial and biological membranes. J. Gen. Physiol. 112:727-736.
34. Patel, A. J., Lauritzen, I., Lazdunski, M., and Honoré, E. 1998. Disruption of mitochondrial respiration inhibits volume-regulated anion channels and provokes neuronal cell swelling. J. Neurosci. 18:3117-3123.