Blockade of class IB phosphoinositide-3 kinase ameliorates obesity-induced inflammation and insulin resistance

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 14, 2011, Pages 5753-5758

  Kobayashi, Naoki ^a   Ueki, Kohjiro ^a   Okazaki, Yukiko ^a   Iwane, Aya ^a   Kubota, Naoto ^a,b   Ohsugi, Mitsuru ^a   Awazawa, Motoharu ^a,b   Kobayashi, Masatoshi ^a   Sasako, Takayoshi ^a   Kaneko, Kazuma ^a   Suzuki, Miho ^a   Nishikawa, Yoshitaka ^a   Hara, Kazuo ^a   Yoshimura, Kotaro ^a   Koshima, Isao ^a   Goyama, Susumu ^a   Murakami, Koji ^c   Sasaki, Junko ^d   Nagai, Ryozo ^e   Kurokawa, Mineo ^a   Sasaki, Takehiko ^d   Kadowaki, Takashi ^a,b   more..

^a UNIVERSITY OF TOKYO   (Japan)

^b NATIONAL INSTITUTE OF HEALTH AND NUTRITION   (Japan)

^c KYORIN PHARMACEUTICAL CO LTD   (Japan)

^d AKITA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

5 (6 QUINOXALINYLMETHYLENE) 2,4 THIAZOLIDINEDIONE; PHOSPHATIDYLINOSITOL 3 KINASE GAMMA;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CONFERENCE PAPER; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE COURSE; ENZYME INHIBITION; GENE DELETION; INFLAMMATION; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIVER; MACROPHAGE; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALIA; MURINAE; MUS;

EID: 79955012753     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1016430108     Document Type: Article

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