-
1
-
-
2942667688
-
Development of insulin resistance and obesity in mice overexpressing cellular glutathione peroxidase
-
McClung, J.P. et al. Development of insulin resistance and obesity in mice overexpressing cellular glutathione peroxidase. Proc. Natl. Acad. Sci. USA 101, 8852-8857 (2004).
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 8852-8857
-
-
McClung, J.P.1
-
2
-
-
0037177625
-
Genetic dissection of transcriptional regulation in budding yeast
-
Brem, R.B., Yvert, G., Clinton, R. & Kruglyak, L. Genetic dissection of transcriptional regulation in budding yeast. Science 296, 752-755 (2002).
-
(2002)
Science
, vol.296
, pp. 752-755
-
-
Brem, R.B.1
Yvert, G.2
Clinton, R.3
Kruglyak, L.4
-
3
-
-
0035827344
-
In silico mapping of complex disease-related traits in mice
-
Grupe, A. et al. In silico mapping of complex disease-related traits in mice. Science 292, 1915-1918 (2001).
-
(2001)
Science
, vol.292
, pp. 1915-1918
-
-
Grupe, A.1
-
4
-
-
5944254200
-
Identification of complement factor 5 as a susceptibility locus for experimental allergic asthma
-
Karp, C.L. et al. Identification of complement factor 5 as a susceptibility locus for experimental allergic asthma. Nat. Immunol. 1, 221-226 (2000).
-
(2000)
Nat. Immunol.
, vol.1
, pp. 221-226
-
-
Karp, C.L.1
-
5
-
-
18544382234
-
Genetic analysis of the mouse brain proteome
-
Klose, J. et al. Genetic analysis of the mouse brain proteome. Nat. Genet. 30, 385-393 (2002).
-
(2002)
Nat. Genet.
, vol.30
, pp. 385-393
-
-
Klose, J.1
-
6
-
-
7444225272
-
In silico genetics: Identification of a functional element regulating H2-Ealpha gene expression
-
Liao, G. et al. In silico genetics: identification of a functional element regulating H2-Ealpha gene expression. Science 306, 690-695 (2004).
-
(2004)
Science
, vol.306
, pp. 690-695
-
-
Liao, G.1
-
7
-
-
8844244726
-
Genetic inheritance of gene expression in human cell lines
-
Monks, S.A. et al. Genetic inheritance of gene expression in human cell lines. Am. J. Hum. Genet. 75, 1094-1105 (2004).
-
(2004)
Am. J. Hum. Genet.
, vol.75
, pp. 1094-1105
-
-
Monks, S.A.1
-
8
-
-
4043128071
-
Genetic analysis of genome-wide variation in human gene expression
-
Morley, M. et al. Genetic analysis of genome-wide variation in human gene expression. Nature 430, 743-747 (2004).
-
(2004)
Nature
, vol.430
, pp. 743-747
-
-
Morley, M.1
-
9
-
-
0037456823
-
Genetics of gene expression surveyed in maize, mouse and man
-
Schadt, E.E. et al. Genetics of gene expression surveyed in maize, mouse and man. Nature 422, 297-302 (2003).
-
(2003)
Nature
, vol.422
, pp. 297-302
-
-
Schadt, E.E.1
-
10
-
-
20144383240
-
Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics'
-
Bystrykh, L. et al. Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics'. Nat. Genet. 37, 225-232 (2005).
-
(2005)
Nat. Genet.
, vol.37
, pp. 225-232
-
-
Bystrykh, L.1
-
11
-
-
20144386111
-
Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function
-
Chesler, E.J. et al. Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function. Nat. Genet. 37, 233-242 (2005).
-
(2005)
Nat. Genet.
, vol.37
, pp. 233-242
-
-
Chesler, E.J.1
-
12
-
-
20144377218
-
Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease
-
Hubner, N. et al. Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease. Nat. Genet. 37, 243-253 (2005).
-
(2005)
Nat. Genet.
, vol.37
, pp. 243-253
-
-
Hubner, N.1
-
13
-
-
0032561246
-
The transcriptional program of sporulation in budding yeast
-
Chu, S. et al. The transcriptional program of sporulation in budding yeast. Science 282, 699-705 (1998).
-
(1998)
Science
, vol.282
, pp. 699-705
-
-
Chu, S.1
-
14
-
-
0032441150
-
Cluster analysis and display of genome-wide expression patterns
-
Eisen, M.B., Spellman, P.T., Brown, P.O. & Botstein, D. Cluster analysis and display of genome-wide expression patterns. Proc. Natl. Acad. Sci. USA 95, 14863-14868 (1998).
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 14863-14868
-
-
Eisen, M.B.1
Spellman, P.T.2
Brown, P.O.3
Botstein, D.4
-
15
-
-
0034616930
-
Functional discovery via a compendium of expression profiles
-
Hughes, T.R. et al. Functional discovery via a compendium of expression profiles. Cell 102, 109-126 (2000).
-
(2000)
Cell
, vol.102
, pp. 109-126
-
-
Hughes, T.R.1
-
16
-
-
0038054341
-
PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
-
Mootha, V.K. et al. PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat. Genet. 34, 267-273 (2003).
-
(2003)
Nat. Genet.
, vol.34
, pp. 267-273
-
-
Mootha, V.K.1
-
17
-
-
0034704219
-
Functional genomics identifies monopolin: A kinetochore protein required for segregation of homologs during meiosis i
-
Toth, A. et al. Functional genomics identifies monopolin: a kinetochore protein required for segregation of homologs during meiosis i. Cell 103, 1155-1168 (2000).
-
(2000)
Cell
, vol.103
, pp. 1155-1168
-
-
Toth, A.1
-
18
-
-
0345876776
-
Genetic loci determining bone density in mice with diet-induced atherosclerosis
-
Drake, T.A. et al. Genetic loci determining bone density in mice with diet-induced atherosclerosis. Physiol. Genomics 5, 205-215 (2001).
-
(2001)
Physiol. Genomics
, vol.5
, pp. 205-215
-
-
Drake, T.A.1
-
19
-
-
0034277623
-
Genetics of atherosclerosis: The search for genes acting at the level of the vessel wall
-
Villa-Colinayo, V., Shi, W., Araujo, J. & Lusis, A.J. Genetics of atherosclerosis: the search for genes acting at the level of the vessel wall. Curr. Atheroscler. Rep. 2, 380-389 (2000).
-
(2000)
Curr. Atheroscler. Rep.
, vol.2
, pp. 380-389
-
-
Villa-Colinayo, V.1
Shi, W.2
Araujo, J.3
Lusis, A.J.4
-
20
-
-
0031975307
-
Experimental strategies for the genetic dissection of complex traits in animal models
-
Darvasi, A. Experimental strategies for the genetic dissection of complex traits in animal models. Nat. Genet. 18, 19-24 (1998).
-
(1998)
Nat. Genet.
, vol.18
, pp. 19-24
-
-
Darvasi, A.1
-
21
-
-
18444402182
-
The Ensembl genome database project
-
Hubbard, T. et al. The Ensembl genome database project. Nucleic Acids Res. 30, 38-41 (2002).
-
(2002)
Nucleic Acids Res.
, vol.30
, pp. 38-41
-
-
Hubbard, T.1
-
22
-
-
0037204994
-
A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome
-
Mural, R.J. et al. A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome. Science 296, 1661-1671 (2002).
-
(2002)
Science
, vol.296
, pp. 1661-1671
-
-
Mural, R.J.1
-
23
-
-
1542563409
-
Initial sequencing and comparative analysis of the mouse genome
-
Waterston, R.H. et al. Initial sequencing and comparative analysis of the mouse genome. Nature 420, 520-562 (2002).
-
(2002)
Nature
, vol.420
, pp. 520-562
-
-
Waterston, R.H.1
-
24
-
-
19844366096
-
Cis-acting expression quantitative trait loci in mice
-
Doss, S., Schadt, E.E., Drake, T.A. & Lusis, A.J. Cis-acting expression quantitative trait loci in mice. Genome Res. 15, 681-691 (2005).
-
(2005)
Genome Res.
, vol.15
, pp. 681-691
-
-
Doss, S.1
Schadt, E.E.2
Drake, T.A.3
Lusis, A.J.4
-
25
-
-
9144272249
-
Regulation of bone mass in mice by the lipoxygenase gene Alox15
-
Klein, R.F. et al. Regulation of bone mass in mice by the lipoxygenase gene Alox15. Science 303, 229-232 (2004).
-
(2004)
Science
, vol.303
, pp. 229-232
-
-
Klein, R.F.1
-
26
-
-
22844446947
-
An integrative genomics approach to infer causal associations between gene expression and disease
-
Schadt, E.E. et al. An integrative genomics approach to infer causal associations between gene expression and disease. Nat. Genet. 37, 710-717 (2005).
-
(2005)
Nat. Genet.
, vol.37
, pp. 710-717
-
-
Schadt, E.E.1
-
27
-
-
0037178728
-
Identification of 5-lipoxygenase as a major gene contributing to atherosclerosis susceptibility in mice
-
Mehrabian, M. et al. Identification of 5-lipoxygenase as a major gene contributing to atherosclerosis susceptibility in mice. Circ. Res. 91, 120-126 (2002).
-
(2002)
Circ. Res.
, vol.91
, pp. 120-126
-
-
Mehrabian, M.1
-
28
-
-
0037495055
-
Amino acid differences in the deduced 5-lipoxygenase sequence of CAST atherosclerosis-resistance mice confer impaired activity when introduced into the human ortholog
-
Kuhn, H., Anton, M., Gerth, C. & Habenicht, A. Amino acid differences in the deduced 5-lipoxygenase sequence of CAST atherosclerosis-resistance mice confer impaired activity when introduced into the human ortholog. Arterioscler. Thromb. Vasc. Biol. 23, 1072-1076 (2003).
-
(2003)
Arterioscler. Thromb. Vasc. Biol.
, vol.23
, pp. 1072-1076
-
-
Kuhn, H.1
Anton, M.2
Gerth, C.3
Habenicht, A.4
-
30
-
-
0346003777
-
Adipocyte-specific gene expression and adipogenic steatosis in the mouse liver due to peroxisome proliferator-activated receptor gamma1 (PPARgamma1) overexpression
-
Yu, S. et al. Adipocyte-specific gene expression and adipogenic steatosis in the mouse liver due to peroxisome proliferator-activated receptor gamma1 (PPARgamma1) overexpression. J. Biol. Chem. 278, 498-505 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 498-505
-
-
Yu, S.1
-
31
-
-
3242806720
-
An integrative genomics approach to the reconstruction of gene networks in segregating populations
-
Zhu, J. et al. An integrative genomics approach to the reconstruction of gene networks in segregating populations. Cytogenet. Genome Res. 105, 363-374 (2004).
-
(2004)
Cytogenet. Genome Res.
, vol.105
, pp. 363-374
-
-
Zhu, J.1
-
32
-
-
0033529194
-
Osteopontin-deficient mice are resistant to ovariectomy-induced bone resorption
-
Yoshitake, H., Rittling, S.R., Denhardt, D.T. & Noda, M. Osteopontin-deficient mice are resistant to ovariectomy-induced bone resorption. Proc. Natl. Acad. Sci. USA 96, 8156-8160 (1999).
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 8156-8160
-
-
Yoshitake, H.1
Rittling, S.R.2
Denhardt, D.T.3
Noda, M.4
-
33
-
-
0031892092
-
Obesity and hyperleptinemia in metallothionein (-I and -II) null mice
-
Beattie, J.H. et al. Obesity and hyperleptinemia in metallothionein (-I and -II) null mice. Proc. Natl. Acad. Sci. USA 95, 358-363 (1998).
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 358-363
-
-
Beattie, J.H.1
-
34
-
-
2142808834
-
Fat's loss is bone's gain
-
Pei, L. & Tontonoz, P. Fat's loss is bone's gain. J. Clin. Invest. 113, 805-806 (2004).
-
(2004)
J. Clin. Invest.
, vol.113
, pp. 805-806
-
-
Pei, L.1
Tontonoz, P.2
-
35
-
-
0033569406
-
Molecular classification of cancer: Class discovery and class prediction by gene expression monitoring
-
Golub, T.R. et al. Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. Science 286, 531-537 (1999).
-
(1999)
Science
, vol.286
, pp. 531-537
-
-
Golub, T.R.1
-
36
-
-
0037226593
-
A molecular signature of metastasis in primary solid tumors
-
Ramaswamy, S., Ross, K.N., Lander, E.S. & Golub, T.R. A molecular signature of metastasis in primary solid tumors. Nat. Genet. 33, 49-54 (2003).
-
(2003)
Nat. Genet.
, vol.33
, pp. 49-54
-
-
Ramaswamy, S.1
Ross, K.N.2
Lander, E.S.3
Golub, T.R.4
-
37
-
-
33947219859
-
The functional landscape of mouse gene expression
-
Zhang, W. et al. The functional landscape of mouse gene expression. J. Biol. 3, 21 (2004).
-
(2004)
J. Biol.
, vol.3
, pp. 21
-
-
Zhang, W.1
-
38
-
-
0035072249
-
Expression profiling using microarrays fabricated by an ink-jet oligonucleotide synthesizer
-
Hughes, T.R. et al. Expression profiling using microarrays fabricated by an ink-jet oligonucleotide synthesizer. Nat. Biotechnol. 19, 342-347 (2001).
-
(2001)
Nat. Biotechnol.
, vol.19
, pp. 342-347
-
-
Hughes, T.R.1
-
39
-
-
0037944217
-
Microarray standard data set and figures of merit for comparing data processing methods and experiment designs
-
He, Y.D. et al. Microarray standard data set and figures of merit for comparing data processing methods and experiment designs. Bioinformatics 19, 956-965 (2003).
-
(2003)
Bioinformatics
, vol.19
, pp. 956-965
-
-
He, Y.D.1
-
40
-
-
0035920262
-
Genetic locus in mice that blocks development of atherosclerosis despite extreme hyperlipidemia
-
Mehrabian, M. et al. Genetic locus in mice that blocks development of atherosclerosis despite extreme hyperlipidemia. Circ. Res. 89, 125-130 (2001).
-
(2001)
Circ. Res.
, vol.89
, pp. 125-130
-
-
Mehrabian, M.1
-
41
-
-
0035158822
-
Atherogenic high-fat diet reduces bone mineralization in mice
-
Parhami, F. et al. Atherogenic high-fat diet reduces bone mineralization in mice. J. Bone Miner. Res. 16, 182-188 (2001).
-
(2001)
J. Bone Miner. Res.
, vol.16
, pp. 182-188
-
-
Parhami, F.1
|