Association of Hck genetic polymorphisms with gene expression and COPD

Human Genetics

Volumn 120, Issue 5, 2007, Pages 681-690

  Zhang, Xiaozhu ^a   Mahmudi Azer, Salahaddin ^a   Connett, John E ^b   Anthonisen, Nicholas R ^c   He, Jian Qing ^a   Paré, Peter D ^a   Sandford, Andrew J ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF MINNESOTA   (United States)

^c UNIVERSITY OF MANITOBA   (Canada)

Author keywords

COPD; Gene expression; Genetic polymorphism; Hck

Indexed keywords

HEMATOPOIETIC CELL KINASE; MESSENGER RNA; MYELOPEROXIDASE;

ADULT; ARTICLE; BRONCHODILATATION; CAUCASIAN; CHRONIC OBSTRUCTIVE LUNG DISEASE; CIGARETTE SMOKING; COHORT ANALYSIS; CONTROLLED STUDY; DEGRANULATION; EFFECTOR CELL; FEMALE; GENE DELETION; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE INSERTION; GENETIC ASSOCIATION; GENETIC MODEL; GENETIC POLYMORPHISM; HUMAN; HUMAN CELL; HYPOTHESIS; INTRON; LUNG FUNCTION; MAJOR CLINICAL STUDY; MALE; MEDIATOR RELEASE; NEUTROPHIL; NORMAL HUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; RESPIRATORY TRACT INFLAMMATION; SINGLE NUCLEOTIDE POLYMORPHISM; TISSUE INJURY;

ADULT; DNA MUTATIONAL ANALYSIS; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION; GENE FREQUENCY; GENOTYPE; HUMANS; IMMUNOHISTOCHEMISTRY; LINKAGE DISEQUILIBRIUM; MALE; MIDDLE AGED; MUTAGENESIS, INSERTIONAL; MUTATION; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTO-ONCOGENE PROTEINS C-HCK; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RNA, MESSENGER; SEQUENCE DELETION;

EID: 33845643690     PISSN: 03406717     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00439-006-0253-7     Document Type: Article

References (34)

1. The International HapMap Project (2003) Nature 426:789-796
2. Albelda SM, Smith CW, Ward PA (1994) Adhesion molecules and inflammatory injury. FASEB J 8:504-512
3. AltoseMD (2003) Approaches to slowing the progression of COPD. Curr Opin Pulm Med 9:125-130
4. Barlic J, Andrews JD, Kelvin AA, Bosinger SE, DeVries ME, Xu L, Dobransky T, Feldman RD, Ferguson SS, Kelvin DJ (2000) Regulation of tyrosine kinase activation and granule release through beta-arrestin by CXCRI. Nat Immunol 1:227-233
5. Barlic J, Khandaker MH, Mahon E, Andrews J, DeVries ME, Mitchell GB, Rahimpour R, Tan CM, Ferguson SS, Kelvin DJ (1999) beta-arrestins regulate interleukin-8-induced CXCR1 internalization. J Biol Chem 274:16287-16294
6. Berton G, Yan SR, Fumagalli L, Lowell CA (1996) Neutrophil activation by adhesion: Mechanisms and pathophysiological implications. Int J Clin Lab Res 26:160-177
7. Bjorge JD, Pang A, Fujita DJ (2000) Identification of protein-tyrosine phosphatase 1B as the major tyrosine phosphatase activity capable of dephosphorylating and activating c-Src in several human breast cancer cell lines. J Biol Chem 275:41439-41446
8. Borregaard N, Kjeldsen L, Lollike K, Sengelov H (1995) Granules and secretory vesicles of the human neutrophil. Clin Exp Immunol 101(Suppl 1):6-9
9. Boyum A (1968) Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g. Scand J Clin Lab Invest 97(Suppl):77-89
10. Bruch M, Bieth JG (1986) Influence of elastin on the inhibition of leucocyte elastase by alpha 1-proteinase inhibitor and bronchial inhibitor. Potent inhibition of elastin-bound elastase by bronchial inhibitor. Biochem J 238:269-273
11. Burkett K, McNeney B, Graham J (2004) A note on inference of trait associations with SNP haplotypes and other attributes in generalized linear models. Hum Hered 57:200-206
12. Carlson CS, Eberle MA, Rieder MJ, Yi Q, Kruglyak L, Nickerson DA (2004) Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibrium. Am J Hum Genet 74:106-120
13. Connett JE, Kusek JW, Bailey WC, O'Hara P, Wu M (1993) Design of the Lung Health Study: A randomized clinical trial of early intervention for chronic obstructive pulmonary disease. Control Clin Trials 14:3S-19S
14. Decramer M, Gosselink R, Bartsch P, Lofdahl CG, Vincken W, Dekhuijzen R, Vestbo J, Pauwels R, Naeije R, Troosters T (2005) Effect of treatments on the progression of COPD: Report of a workshop held in Leuven, 11-12 March 2004. Thorax 60:343-349
15. Doll R, Peto R, Wheatley K, Gray R, Sutherland I (1994) Mortality in relation to smoking: 40 years' observations on male British doctors. BMJ 309:901-911
16. Egan C, Pang A, Durda D, Cheng HC, Wang JH, Fujita DJ (1999) Activation of Src in human breast tumor cell lines: Elevated levels of phosphotyrosine phosphatase activity that preferentially recognizes the Src carboxy terminal negative regulatory tyrosine 530. Oncogene 18:1227-1237
17. Ernst M, Inglese M, Scholz GM, Harder KW, Clay FJ, Bozinovski S, Waring P, Darwiche R, Kay T, Sly P, Collins R, Turner D, Hibbs ML, Anderson GP, Dunn AR (2002) Constitutive activation of the SRC family kinase Hck results in spontaneous pulmonary inflammation and an enhanced innate immune response. J Exp Med 196:589-604
18. Gutkind JS, Robbins KC (1989) Translocation of the FGR protein-tyrosine kinase as a consequence of neutrophil activation. Proc Natl Acad Sci USA 86:8783-8787
19. Kruglyak L, Nickerson DA (2001) Variation is the spice of life. Nat Genet 27:234-236
20. Lichtenberg U, Quintrell N, Bishop JM (1992) Human protein-tyrosine kinase gene HCK: Expression and structural analysis of the promoter region. Oncogene 7:849-858
21. Lowell CA, Soriano P, Varmus HE (1994) Functional overlap in the src gene family: Inactivation of hck and fgr impairs natural immunity. Genes Dev 8:387-398
22. Lucey EC, Stone PJ, Breuer R, Christensen TG, Calore JD, Catanese A, Franzblau C, Snider GL (1985) Effect of combined human neutrophil cathepsin G and elastase on induction of secretory cell metaplasia and emphysema in hamsters, with in vitro observations on elastolysis by these enzymes. Am Rev Respir Dis 132:362-366
23. MacNee W (2005) Pulmonary and systemic oxidant/antioxidant imbalance in chronic obstructive pulmonary disease. Proc Am Thorac Soc 2:50-60
24. Martin-Martin B, Nabokina SM, Blasi J, Lazo PA, Mollinedo F (2000) Involvement of SNAP-23 and syntaxin 6 in human neutrophil exocytosis. Blood 96:2574-2583
25. Mocsai A, Ligeti E, Lowell CA, Berton G (1999) Adhesion-dependent degranulation of neutrophils requires the Src family kinases Fgr and Hck. J Immunol 162:1120-1126
26. Mohn H, Le Cabec V, Fischer S, Maridonneau-Parini I (1995) The src-family protein-tyrosine kinase p59hck is located on the secretory granules in human neutrophils and translocates towards the phagosome during cell activation. Biochem J 309(Pt 2):657-665
27. Mollinedo F, Martin-Martin B, Calafat J, Nabokina SM, Lazo PA (2003) Role of vesicle-associated membrane protein-2, through Q-soluble N -ethylmaleimide-sensitive factor attachment protein receptor/R-soluble N -ethylmaleimide-sensitive factor attachment protein receptor interaction, in the exocytosis of specific and tertiary granules of human neutrophils. J Immunol 170:1034-1042
28. Rigat B, Hubert C, Alhenc-Gelas F, Cambien F, Corvol P, Soubrier F (1990) An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels. J Clin Invest 86:1343-1346
29. Stockley RA (2002) Neutrophils and the pathogenesis of COPD. Chest 121:151S-155S
30. Venter JC, Adams MD, Myers EW, Li PW, Mural RJ, Sutton GG, Smith HO, Yandell M, Evans CA, Holt RA, Gocayne JD, Amanatides P, Ballew RM, Huson DH, Wortman JR, Zhang Q, Kodira CD, Zheng XH, Chen L, Skupski M, Subramanian G, Thomas PD, Zhang J, Gabor Miklos GL, Nelson C, Broder S, Clark AG, Nadeau J, McKusick VA, Zinder N, Levine AJ, Roberts RJ, Simon M, Slayman C, Hunkapiller M, Bolanos R, Delcher A, Dew I, Fasulo D, Flanigan M, Florea L, Halpern A, Hannenhalli S, Kravitz S, Levy S, Mobarry C, Reinert K, Remington K, Abu-Threideh J, Beasley E, Biddick K, Bonazzi V, Brandon R, Cargill M, Chandramouliswaran I, Charlab R, Chaturvedi K, Deng Z, Di Francesco V, Dunn P, Eilbeck K, Evangelista C, Gabrielian AE, Gan W, Ge W, Gong F, Gu Z, Guan P, Heiman TJ, Higgins ME, Ji RR, Ke Z, Ketchum KA, Lai Z, Lei Y, Li Z, Li J, Liang Y, Lin X, Lu F, Merkulov GV, Milshina N, Moore HM, Naik AK, Narayan VA, Neelam B, Nusskern D, Rusch DB, Salzberg S, Shao W, Shue B, Sun J, Wang Z, Wang A, Wang X, Wang J, Wei M, Wides R, Xiao C, Yan C et al (2001) The sequence of the human genome. Science 291:1304-1351
31. Welch H, Mauran C, Maridonneau-Parini II (1996) Nonreceptor protein-tyrosine kinases in neutrophil activation. Methods 9:607-618
32. Witko-Sarsat V, Rieu P, Descamps-Latscha B, Lesavre P, Halbwachs-Mecarelli L (2000) Neutrophils: Molecules, functions and pathophysiological aspects. Lab Invest 80:617-653
33. Zhou W, Liu G, Miller DP, Thurston SW, Xu LL, Wain JC, Lynch TJ, Su L, Christiani DC (2002) Gene-environment interaction for the ERCC2 polymorphisms and cumulative cigarette smoking exposure in lung cancer. Cancer Res 62:1377-1381
34. Zhou W, Thurston SW, Liu G, Xu LL, Miller DP, Wain JC, Lynch TJ, Su L, Christiani DC (2001) The interaction between microsomal epoxide hydrolase polymorphisms and cumulative cigarette smoking in different histological subtypes of lung cancer. Cancer Epidemiol Biomarkers Prev 10:461-466