메뉴 건너뛰기




Volumn 11, Issue 4, 2010, Pages 1509-1526

Oxidative stress, molecular inflammation and sarcopenia

Author keywords

Chronic inflammation; Interventions; Oxidative stress; Sarcopenia; Signaling

Indexed keywords

ATROGIN 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; MUSCLE RING FINGER 1 PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PROTEIN KINASE B; SOMATOMEDIN C; TRANSCRIPTION FACTOR FOXO;

EID: 77951922812     PISSN: None     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms11041509     Document Type: Review
Times cited : (416)

References (102)
  • 1
    • 0030968884 scopus 로고    scopus 로고
    • Sarcopenia: Origins and clinical relevance
    • Rosenberg, I.H. Sarcopenia: Origins and clinical relevance. J. Nutr. 1997, 127, 990S-991S.
    • (1997) J. Nutr , vol.127
    • Rosenberg, I.H.1
  • 4
    • 0023923274 scopus 로고
    • Muscle atrophy and hypoplasia with aging: Impact of training and food restriction
    • Daw, C.K.; Starnes, J.W.; White, T.P. Muscle atrophy and hypoplasia with aging: Impact of training and food restriction. J. Appl. Physiol. 1988, 64, 2428-2432.
    • (1988) J. Appl. Physiol , vol.64 , pp. 2428-2432
    • Daw, C.K.1    Starnes, J.W.2    White, T.P.3
  • 5
    • 0023856536 scopus 로고
    • What is the cause of the ageing atrophy? Total number, size and proportion of different fiber types studied in whole vastus lateralis muscle from 15- to 83-year-old men
    • Lexell, J.; Taylor, C.C.; Sjostrom, M. What is the cause of the ageing atrophy? Total number, size and proportion of different fiber types studied in whole vastus lateralis muscle from 15- to 83-year-old men. J. Neurol. Sci. 1988, 84, 275-294.
    • (1988) J. Neurol. Sci , vol.84 , pp. 275-294
    • Lexell, J.1    Taylor, C.C.2    Sjostrom, M.3
  • 6
    • 36148957445 scopus 로고    scopus 로고
    • Molecular mechanisms of life- and health- span extension: Role of calorie restriction and exercise intervention
    • Carter, C.S.; Hofer, T.; Seo, A.T.; Leeuwenburgh, C. Molecular mechanisms of life- and health- span extension: Role of calorie restriction and exercise intervention. Appl. Physiol. Nutr. Metab. 2007, 32, 954-966.
    • (2007) Appl. Physiol. Nutr. Metab , vol.32 , pp. 954-966
    • Carter, C.S.1    Hofer, T.2    Seo, A.T.3    Leeuwenburgh, C.4
  • 7
    • 33846243745 scopus 로고    scopus 로고
    • An integrated view of oxidative stress in aging: Basic mechanisms, functional effects, and pathological considerations
    • Kregel, K.C.; Zhang, H.J. An integrated view of oxidative stress in aging: Basic mechanisms, functional effects, and pathological considerations. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2007, 292, R18-R36.
    • (2007) Am. J. Physiol. Regul. Integr. Comp. Physiol , vol.292
    • Kregel, K.C.1    Zhang, H.J.2
  • 8
    • 57349109417 scopus 로고    scopus 로고
    • Age-dependent increase in oxidative stress in gastrocnemius muscle with unloading
    • Siu, P.M.; Pistilli, E.E.; Alway, S.E. Age-dependent increase in oxidative stress in gastrocnemius muscle with unloading. J. Appl. Physiol. 2008, 105, 1695-705.
    • (2008) J. Appl. Physiol , vol.105 , pp. 1695-705
    • Siu, P.M.1    Pistilli, E.E.2    Alway, S.E.3
  • 9
    • 34047213532 scopus 로고    scopus 로고
    • Oxidative stress, chronic disease, and muscle wasting
    • Moylan, J.S.; Reid, M.B. Oxidative stress, chronic disease, and muscle wasting. Muscle Nerve. 2007, 35, 411-429.
    • (2007) Muscle Nerve , vol.35 , pp. 411-429
    • Moylan, J.S.1    Reid, M.B.2
  • 10
    • 33846829277 scopus 로고    scopus 로고
    • Carotenoids as protection against sarcopenia in older adults. Arch. Biochem
    • Samba, R.D.; Lauretani, F.; Ferrucci, L. Carotenoids as protection against sarcopenia in older adults. Arch. Biochem. Biophys. 2007, 458, 141-145.
    • (2007) Biophys , vol.458 , pp. 141-145
    • Samba, R.D.1    Lauretani, F.2    Ferrucci, L.3
  • 12
    • 66149092830 scopus 로고    scopus 로고
    • Aging, exercise and muscle protein metabolism
    • Koopman, R.; van Loon, L.J. Aging, exercise and muscle protein metabolism. J. Appl. Physiol. 2009, 106, 2040-2048.
    • (2009) J. Appl. Physiol , vol.106 , pp. 2040-2048
    • Koopman, R.1    van Loon, L.J.2
  • 14
    • 0035722694 scopus 로고    scopus 로고
    • Tumor necrosis factor-α and muscle wasting: A cellular perspective
    • Reid, M.B.; Li, Y.P. Tumor necrosis factor-α and muscle wasting: A cellular perspective. Respir. Res. 2001, 2, 269-272.
    • (2001) Respir. Res , vol.2 , pp. 269-272
    • Reid, M.B.1    Li, Y.P.2
  • 16
    • 17444418617 scopus 로고    scopus 로고
    • Age-related differences in skeletal muscle protein synthesis: Relation to markers of immune activation
    • Toth, M.J.; Matthews, D.E.; Tracy, R.P.; Previs, M.J. Age-related differences in skeletal muscle protein synthesis: Relation to markers of immune activation. Am. J. Physiol. Endocrinol. Metab. 2005, 288, E883-E891.
    • (2005) Am. J. Physiol. Endocrinol. Metab , vol.288
    • Toth, M.J.1    Matthews, D.E.2    Tracy, R.P.3    Previs, M.J.4
  • 17
    • 0037927688 scopus 로고    scopus 로고
    • Catabolism of aging: Is it an inflammatory process?
    • Roubenoff, R. Catabolism of aging: Is it an inflammatory process? Curr. Opin. Clin. Nutr. Metab. Care. 2003, 6, 295-299.
    • (2003) Curr. Opin. Clin. Nutr. Metab. Care , vol.6 , pp. 295-299
    • Roubenoff, R.1
  • 18
    • 33748643416 scopus 로고    scopus 로고
    • Mitochondrial DNA-deletion mutations accumulate intracellularly to detrimental levels in aged human skeletal muscle fibers
    • Bua, E.; Johnson, J.; Herbst, A.; Delong, B.; McKenzie, D.; Salamat, S.; Aiken, J.M. Mitochondrial DNA-deletion mutations accumulate intracellularly to detrimental levels in aged human skeletal muscle fibers. Am. J. Hum. Genet. 2006, 79, 469-480.
    • (2006) Am. J. Hum. Genet , vol.79 , pp. 469-480
    • Bua, E.1    Johnson, J.2    Herbst, A.3    Delong, B.4    McKenzie, D.5    Salamat, S.6    Aiken, J.M.7
  • 19
    • 58949095755 scopus 로고    scopus 로고
    • TNF-induced mitochondrial damage: A link between mitochondrial complex I activity and left ventricular dysfunction
    • Mariappan, N.; Elks, C.M.; Fink, B.; Francis, J. TNF-induced mitochondrial damage: A link between mitochondrial complex I activity and left ventricular dysfunction. Free Radic Biol. Med. 2009, 46, 462-470.
    • (2009) Free Radic Biol. Med , vol.46 , pp. 462-470
    • Mariappan, N.1    Elks, C.M.2    Fink, B.3    Francis, J.4
  • 21
    • 46649114727 scopus 로고    scopus 로고
    • Age- related activation of mitochondrial caspase-independent apoptotic signaling in rat gastrocnemius muscle
    • Marzetti, E.; Wohlgemutz, S.E.; Lees, H.A.; Chung, H.; Giovannini, S.; Leeuwenburgh, C. Age- related activation of mitochondrial caspase-independent apoptotic signaling in rat gastrocnemius muscle. Mech. Ageing Dev. 2008, 129, 542-549.
    • (2008) Mech. Ageing Dev , vol.129 , pp. 542-549
    • Marzetti, E.1    Wohlgemutz, S.E.2    Lees, H.A.3    Chung, H.4    Giovannini, S.5    Leeuwenburgh, C.6
  • 23
    • 4544293878 scopus 로고    scopus 로고
    • IGF-1 stimulates muscle growth by suppressing protein breakdown and expression of atrphy-related ubiquitin-ligases, atrogin-1 and MuRF1
    • Sacheck, J.M.; Ohtsuka, A.; McLary, S.C.; Goldberg, A.L. IGF-1 stimulates muscle growth by suppressing protein breakdown and expression of atrphy-related ubiquitin-ligases, atrogin-1 and MuRF1. Am. J. Physiol. Endocrinol. Metab. 2004, 287, E591-E601.
    • (2004) Am. J. Physiol. Endocrinol. Metab , vol.287
    • Sacheck, J.M.1    Ohtsuka, A.2    McLary, S.C.3    Goldberg, A.L.4
  • 24
    • 0142106463 scopus 로고    scopus 로고
    • Age-related differences in the des IGF-I-mediated activation of Akt-1 and p70 S6K in mouse skeletal muscle
    • Li, M.; Li, C.; Parkhouse, W.S. Age-related differences in the des IGF-I-mediated activation of Akt-1 and p70 S6K in mouse skeletal muscle. Mech. Ageing Dev. 2003, 124, 771-778.
    • (2003) Mech. Ageing Dev , vol.124 , pp. 771-778
    • Li, M.1    Li, C.2    Parkhouse, W.S.3
  • 27
    • 13244298415 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 (IGF-1) inversely regulates atrophy-induced genes via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR) pathway
    • Latres, E.; Amini, A.R.; Amini, A.A.; Griffiths, J.; Martin, F.J.; Wei, Y.; Lin, H.C.; Yancopoulous, G.D.; Glass, D.J. Insulin-like growth factor-1 (IGF-1) inversely regulates atrophy-induced genes via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR) pathway. J. Biol. Chem. 2005, 280, 2737-2744.
    • (2005) J. Biol. Chem , vol.280 , pp. 2737-2744
    • Latres, E.1    Amini, A.R.2    Amini, A.A.3    Griffiths, J.4    Martin, F.J.5    Wei, Y.6    Lin, H.C.7    Yancopoulous, G.D.8    Glass, D.J.9
  • 29
    • 33750735034 scopus 로고    scopus 로고
    • MTOR signaling and the molecular adaptation to resistance exercise
    • Bodine, S.C. mTOR signaling and the molecular adaptation to resistance exercise. Med. Sci. Sprots Exerc. 2006, 38, 1950-1957.
    • (2006) Med. Sci. Sprots Exerc , vol.38 , pp. 1950-1957
    • Bodine, S.C.1
  • 30
    • 33744939435 scopus 로고    scopus 로고
    • Increase in S6K1 phosphorylation in human skeletal muscle following resistance exercise occurs mainly in type IImuscle fibers
    • Koopman, R.; Zorenc, A.H.; Gransier, R.J.; Cameron-Smith, D.; van Loon L.J. Increase in S6K1 phosphorylation in human skeletal muscle following resistance exercise occurs mainly in type IImuscle fibers. Am. J. Physiol. Endocrinol. Metab. 2006, 290, E1245-E1252.
    • (2006) Am. J. Physiol. Endocrinol. Metab , vol.290
    • Koopman, R.1    Zorenc, A.H.2    Gransier, R.J.3    Cameron-Smith, D.4    van Loon, L.J.5
  • 31
    • 0035860421 scopus 로고    scopus 로고
    • Age-related loss of skeletal muscle function and the inability to express the autocrine form of insulin-like growth factor-1 (MGF) in response to mechanical overload
    • Owino, V.; Yang, S.Y.; Goldspink, G. Age-related loss of skeletal muscle function and the inability to express the autocrine form of insulin-like growth factor-1 (MGF) in response to mechanical overload. FEBS Lett. 2001, 505, 259-263.
    • (2001) FEBS Lett , vol.505 , pp. 259-263
    • Owino, V.1    Yang, S.Y.2    Goldspink, G.3
  • 32
    • 33646357762 scopus 로고    scopus 로고
    • Aging-sensitive cellular and molecular mechanisms associated with skeletal muscle hypertrophy
    • Haddad, F.; Adams, G.R. Aging-sensitive cellular and molecular mechanisms associated with skeletal muscle hypertrophy. J. Appl. Physoil. 2006, 100, 1188-1203.
    • (2006) J. Appl. Physoil , vol.100 , pp. 1188-1203
    • Haddad, F.1    Adams, G.R.2
  • 33
    • 41849117809 scopus 로고    scopus 로고
    • Regulation of IGF-I Function by Proinflammatory Cytokines: At the Interface of Immunology and Endocrinology
    • O'Connor, J.C.; McCusker, R.H.; Strle, K.; Johnson, R.W.; Dantzer, R; Kelley, K.W. Regulation of IGF-I Function by Proinflammatory Cytokines: At the Interface of Immunology and Endocrinology. Cell Immunol. 2008, 252, 91-110.
    • (2008) , vol.252 , pp. 91-110
    • O'Connor, J.C.1    McCusker, R.H.2    Strle, K.3    Johnson, R.W.4    Dantzer, R.5    Kelley, K.W.6
  • 34
    • 58349097705 scopus 로고    scopus 로고
    • Insulin/IGF-1 and ROS signaling pathway cross-talk in aging and longevity determination
    • Papaconstantinou, J. Insulin/IGF-1 and ROS signaling pathway cross-talk in aging and longevity determination. Mol. Cell Endocrinol. 2009, 299, 89-100.
    • (2009) Mol. Cell Endocrinol , vol.299 , pp. 89-100
    • Papaconstantinou, J.1
  • 36
    • 33745206561 scopus 로고    scopus 로고
    • Impaired overload-induced muscle growth is associated with diminished translational signaling in aged rat fast-twitch skeletal muscle
    • Thomson, D.M.; Gordon, S.E. Impaired overload-induced muscle growth is associated with diminished translational signaling in aged rat fast-twitch skeletal muscle. J. Physiol. 2006, 574, 291-305.
    • (2006) J. Physiol , vol.574 , pp. 291-305
    • Thomson, D.M.1    Gordon, S.E.2
  • 37
    • 33646474863 scopus 로고    scopus 로고
    • Age associated decrease in contraction-induced activation of downstream targets of Akt/mTOR signaling in skeletal muscle
    • Funai, F.; Parkington, J.D.; Carambula, S.; Fielding, R.A. Age associated decrease in contraction-induced activation of downstream targets of Akt/mTOR signaling in skeletal muscle. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2006, 290, R1080-R1086.
    • (2006) Am. J. Physiol. Regul. Integr. Comp. Physiol , vol.290
    • Funai, F.1    Parkington, J.D.2    Carambula, S.3    Fielding, R.A.4
  • 38
    • 39449100832 scopus 로고    scopus 로고
    • Human sarcopenia reveals an increase in SOCS- 3 and myostatin and a reduced efficiency of akt phosphorylation
    • Léger, B.; Bock, K.D.; Hespel, P.; Russell, A.P. Human sarcopenia reveals an increase in SOCS- 3 and myostatin and a reduced efficiency of akt phosphorylation. Rejuv. Res. 2008, 11, 163-175.
    • (2008) Rejuv. Res , vol.11 , pp. 163-175
    • Léger, B.1    Bock, K.D.2    Hespel, P.3    Russell, A.P.4
  • 39
    • 55949123726 scopus 로고    scopus 로고
    • Antioxidant Supplementation Restores Defective Leucine Stimulation of Protein Synthesis in Skeletal Muscle from Old Rats
    • Marzani, B.; Balage, M.; Vénien, A.; Astruc, T.; Papet, I.; Dardevet, D.; Mosoni, L. Antioxidant Supplementation Restores Defective Leucine Stimulation of Protein Synthesis in Skeletal Muscle from Old Rats. J. Nutr. 2008, 138, 2205-2211.
    • (2008) J. Nutr , vol.138 , pp. 2205-2211
    • Marzani, B.1    Balage, M.2    Vénien, A.3    Astruc, T.4    Papet, I.5    Dardevet, D.6    Mosoni, L.7
  • 40
    • 17644379936 scopus 로고    scopus 로고
    • FOXO transcription factors in cell- cycle regulation and the response to oxidative stress
    • Furukawa-Hibi, Y.; Kobayashi, Y.; Chen, C.; Motoyama, N. FOXO transcription factors in cell- cycle regulation and the response to oxidative stress. Antioxid Redox Signal. 2005, 7, 752-760.
    • (2005) Antioxid Redox Signal , vol.7 , pp. 752-760
    • Furukawa-Hibi, Y.1    Kobayashi, Y.2    Chen, C.3    Motoyama, N.4
  • 42
    • 4544358547 scopus 로고    scopus 로고
    • Skeletal muscle FOXO1(FKHR) transgenic mice have less skeletal muscle mass, down-regulated type I(slow twitch /red muscle) fiber genes, and impaired glycemic control
    • Kamei, Y.; Miura, S.; Suzuki, M.; Kai, Y.; Mizukami, J.; Taniguchi, T.; Mochida, K.; Hata, T.; Matsuda, J.; Aburatani, H.; et al. Skeletal muscle FOXO1(FKHR) transgenic mice have less skeletal muscle mass, down-regulated type I(slow twitch /red muscle) fiber genes, and impaired glycemic control. J. Biol. Chem. 2004, 279, 41114-41123.
    • (2004) J. Biol. Chem , vol.279 , pp. 41114-41123
    • Kamei, Y.1    Miura, S.2    Suzuki, M.3    Kai, Y.4    Mizukami, J.5    Taniguchi, T.6    Mochida, K.7    Hata, T.8    Matsuda, J.9    Aburatani, H.10
  • 43
    • 2042425906 scopus 로고    scopus 로고
    • The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors
    • Stitt, T.N.; Drujan, D.; Clarke, B.A.; Panaro, F.; Timofeyva, Y.; Kline, W.O.; Gonzalez, M.; Yancopoulos, G.D.; Glass, D.J. The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors. Mol. Cell. 2004, 14, 395-403.
    • (2004) Mol. Cell , vol.14 , pp. 395-403
    • Stitt, T.N.1    Drujan, D.2    Clarke, B.A.3    Panaro, F.4    Timofeyva, Y.5    Kline, W.O.6    Gonzalez, M.7    Yancopoulos, G.D.8    Glass, D.J.9
  • 45
    • 6944247865 scopus 로고    scopus 로고
    • Increased nuclear proteins in muscle satellite cells in aged animals as compared to young growing animals
    • Machida S.; Booth, F.W. Increased nuclear proteins in muscle satellite cells in aged animals as compared to young growing animals. Exp. Gerontol. 2004, 39, 1521-1525.
    • (2004) Exp. Gerontol , vol.39 , pp. 1521-1525
    • Machida, S.1    Booth, F.W.2
  • 49
    • 33744542153 scopus 로고    scopus 로고
    • Tumor necrosis factor-like weak inducer of apoptosis inhibits skeletal myogenesis through sustained activation of nuclear factor-kappaB and degradation of MyoD protein
    • Dogra C.; Changotra, H.; Mohan, S.; Kumar, A. Tumor necrosis factor-like weak inducer of apoptosis inhibits skeletal myogenesis through sustained activation of nuclear factor-kappaB and degradation of MyoD protein. J. Biol. Chem. 2006, 281, 10327-10336.
    • (2006) J. Biol. Chem , vol.281 , pp. 10327-10336
    • Dogra, C.1    Changotra, H.2    Mohan, S.3    Kumar, A.4
  • 51
    • 11144317940 scopus 로고    scopus 로고
    • Disruption of either the Nfkb1 or the Bcl3 gene inhibits skeletal muscle atrophy
    • Hunter, R.B.; Kandarian, S.C. Disruption of either the Nfkb1 or the Bcl3 gene inhibits skeletal muscle atrophy. J. Clin. Invest. 2004, 114, 1504-1511.
    • (2004) J. Clin. Invest , vol.114 , pp. 1504-1511
    • Hunter, R.B.1    Kandarian, S.C.2
  • 52
    • 33947097911 scopus 로고    scopus 로고
    • Alterations in mRNA expression and protein products following spinal cord injury in humans
    • Urso, M.L.; Chen, Y.W.; Scrimgeour, A.G.; Lee, P.C.; Lee, K.F.; Clarkson, P.M. Alterations in mRNA expression and protein products following spinal cord injury in humans. J. Physiol. 2007, 579, 877-892.
    • (2007) J. Physiol , vol.579 , pp. 877-892
    • Urso, M.L.1    Chen, Y.W.2    Scrimgeour, A.G.3    Lee, P.C.4    Lee, K.F.5    Clarkson, P.M.6
  • 54
    • 16344385647 scopus 로고    scopus 로고
    • Muscle fiber specific apoptosis and TNF-α signaling in sarcopenia are attenuated by life-long calorie restriction
    • Phillips, T.; Leeuwenburgh, C. Muscle fiber specific apoptosis and TNF-α signaling in sarcopenia are attenuated by life-long calorie restriction. FASEB J. 2005, 19, 668-670.
    • (2005) FASEB J , vol.19 , pp. 668-670
    • Phillips, T.1    Leeuwenburgh, C.2
  • 55
    • 14644400387 scopus 로고    scopus 로고
    • TNF-alpha acts via p38 MAPK to stimulate expression of the ubiquitin ligase atrogin1/MAFbx in skeletal muscle
    • Li, Y.P.; Chen, Y.; John, J.; Moylan, J.; Jin, B.; Mann, D.L.; Reid, M.B. TNF-alpha acts via p38 MAPK to stimulate expression of the ubiquitin ligase atrogin1/MAFbx in skeletal muscle. FASEB J. 2005, 19, 362-370.
    • (2005) FASEB J , vol.19 , pp. 362-370
    • Li, Y.P.1    Chen, Y.2    John, J.3    Moylan, J.4    Jin, B.5    Mann, D.L.6    Reid, M.B.7
  • 56
    • 0032562574 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase pathway is involved in the differentiation of muscle cells
    • Gredinger, E.; Gerber, A.; Tamir, Y.; Tapscott, S.; Bengal, E. Mitogen-activated protein kinase pathway is involved in the differentiation of muscle cells. J. Biol. Chem. 1998, 273, 10436-10444.
    • (1998) J. Biol. Chem , vol.273 , pp. 10436-10444
    • Gredinger, E.1    Gerber, A.2    Tamir, Y.3    Tapscott, S.4    Bengal, E.5
  • 58
    • 0037444470 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase (MAPK) pathway activation: Effects of age and acute exercise on human skeletal muscle
    • Williamson, D.; Gallagher, P.; Harber, M.; Hollon, C.; Trappe, S. Mitogen-activated protein kinase (MAPK) pathway activation: Effects of age and acute exercise on human skeletal muscle. J. Physiol. 2003, 547, 977-987.
    • (2003) J. Physiol , vol.547 , pp. 977-987
    • Williamson, D.1    Gallagher, P.2    Harber, M.3    Hollon, C.4    Trappe, S.5
  • 60
    • 0028935270 scopus 로고
    • Pro- inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine
    • Raingeaud, J.; Gupta, S.; Rogers, J.; Dickens, M.; Han, J.; Ulevitch, R.J.; Davis, R.J. Pro- inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine. J. Biol. Chem. 1995, 270, 7420-7426.
    • (1995) J. Biol. Chem , vol.270 , pp. 7420-7426
    • Raingeaud, J.1    Gupta, S.2    Rogers, J.3    Dickens, M.4    Han, J.5    Ulevitch, R.J.6    Davis, R.J.7
  • 61
    • 33644862368 scopus 로고    scopus 로고
    • JNK signaling pathway is a key modulator in cell death mediated by reactive oxygen and nitrogen species
    • Shen, H.M.; Liu, Z.G. JNK signaling pathway is a key modulator in cell death mediated by reactive oxygen and nitrogen species. Free Radic. Biol. Med. 2006, 40, 928-939.
    • (2006) Free Radic. Biol. Med , vol.40 , pp. 928-939
    • Shen, H.M.1    Liu, Z.G.2
  • 62
    • 44149119740 scopus 로고    scopus 로고
    • Involvement of oxidative stress and caspase 2-mediated intrinsic pathway signaling in age-related increase in muscle cell apoptosis in mice
    • Braga, M.; Sinha-Hikim, A.P.; Datta, S.; Ferrini, M.G.; Brown, D.; Kovacheva, E.L.; Gonzalez- Cadavid, N.F.; Sinha-Hikim, I. Involvement of oxidative stress and caspase 2-mediated intrinsic pathway signaling in age-related increase in muscle cell apoptosis in mice. Apoptosis 2008, 13, 822-832.
    • (2008) Apoptosis , vol.13 , pp. 822-832
    • Braga, M.1    Sinha-Hikim, A.P.2    Datta, S.3    Ferrini, M.G.4    Brown, D.5    Kovacheva, E.L.6    Gonzalez- Cadavid, N.F.7    Sinha-Hikim, I.8
  • 63
    • 23944456384 scopus 로고    scopus 로고
    • Skeletal muscle hypertrophy and atrophy signaling pathways
    • Glass, D.J. Skeletal muscle hypertrophy and atrophy signaling pathways. Int. J. Biochem. Cell Biol. 2005, 37, 1974-1984.
    • (2005) Int. J. Biochem. Cell Biol , vol.37 , pp. 1974-1984
    • Glass, D.J.1
  • 65
    • 9644270401 scopus 로고    scopus 로고
    • Atrogin-1/muscle atrophy F- box inhibits calcineurin-dependent cardiac hypertrophy by participating in an SCF ubiquitin ligase complex
    • Li, H.H.; Kedar, V.; Zhang, C.; Arya, R.; Wang, D.Z.; Patterson, C. Atrogin-1/muscle atrophy F- box inhibits calcineurin-dependent cardiac hypertrophy by participating in an SCF ubiquitin ligase complex. J. Clin. Invest. 2004, 114, 1058-1071.
    • (2004) J. Clin. Invest , vol.114 , pp. 1058-1071
    • Li, H.H.1    Kedar, V.2    Zhang, C.3    Arya, R.4    Wang, D.Z.5    Patterson, C.6
  • 66
    • 2042425906 scopus 로고    scopus 로고
    • The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors
    • Stitt, T.N.; Drujan, D.; Clarke, B.A.; Panaro, F.J.; Timofeyva, Y.; Kline, W.O.; Gonzalez, M.; Yancopoulos, G.D.; Glass, D.J. The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors. Mol. Cell 2004, 14, 395-403.
    • (2004) Mol. Cell , vol.14 , pp. 395-403
    • Stitt, T.N.1    Drujan, D.2    Clarke, B.A.3    Panaro, F.J.4    Timofeyva, Y.5    Kline, W.O.6    Gonzalez, M.7    Yancopoulos, G.D.8    Glass, D.J.9
  • 68
    • 33748526240 scopus 로고    scopus 로고
    • Atrophy-related ubiquitin ligases, atrogin-1 and MuRF1 are up-regulated in aged rat tibialis anterior muscle
    • Clavel, S.; Coldefy, A.S.; Kurkdjian, E.; Salles, J.; Margaritis, I.; Derijard, B. Atrophy-related ubiquitin ligases, atrogin-1 and MuRF1 are up-regulated in aged rat tibialis anterior muscle. Mech. Ageing Dev. 2006, 127, 794-801.
    • (2006) Mech. Ageing Dev , vol.127 , pp. 794-801
    • Clavel, S.1    Coldefy, A.S.2    Kurkdjian, E.3    Salles, J.4    Margaritis, I.5    Derijard, B.6
  • 69
    • 33746611524 scopus 로고    scopus 로고
    • Atrogin-1/MAFbx and MuRF1 are downregulated in aging-related loss of skeletal muscle
    • Edstrom, E.; Altun, M.; Hagglund, M.; Ulfhake, B. Atrogin-1/MAFbx and MuRF1 are downregulated in aging-related loss of skeletal muscle. J. Gerontol. A: Biol. Sci. Med. Sci. 2006, 61, 663-674.
    • (2006) J. Gerontol. A: Biol. Sci. Med. Sci , vol.61 , pp. 663-674
    • Edstrom, E.1    Altun, M.2    Hagglund, M.3    Ulfhake, B.4
  • 70
    • 25644432770 scopus 로고    scopus 로고
    • Contributions of the ubiquitin- proteasome pathway and apoptosis to human skeletal muscle wasting with age
    • Whitman, S.A.; Wacker, M.J.; Richmond, S.R.; Godard, M.P. Contributions of the ubiquitin- proteasome pathway and apoptosis to human skeletal muscle wasting with age. Pflugers Arch. 2005, 450, 437-446.
    • (2005) Pflugers Arch , vol.450 , pp. 437-446
    • Whitman, S.A.1    Wacker, M.J.2    Richmond, S.R.3    Godard, M.P.4
  • 71
    • 38749140252 scopus 로고    scopus 로고
    • Proteolytic gene expression differs at rest and after resistance exercise between young and old women
    • Raue, U.; Slivka, D.; Jemiolo, B.; Hollon, C.; Trappe, S. Proteolytic gene expression differs at rest and after resistance exercise between young and old women. J. Gerontol. A Biol. Sci. Med. Sci. 2007, 62, 1407-1412.
    • (2007) J. Gerontol. a Biol. Sci. Med. Sci , vol.62 , pp. 1407-1412
    • Raue, U.1    Slivka, D.2    Jemiolo, B.3    Hollon, C.4    Trappe, S.5
  • 72
    • 47949104798 scopus 로고    scopus 로고
    • The role of exercise and PGC1α in inflammation and chronic disease
    • Christoph, H.; Spiegelman, M. The role of exercise and PGC1α in inflammation and chronic disease. Nature 2008, 454, 463-469.
    • (2008) Nature , vol.454 , pp. 463-469
    • Christoph, H.1    Spiegelman, M.2
  • 73
    • 46749125376 scopus 로고    scopus 로고
    • Transcriptional control of mitochondrial biogenesis: The central role of PGC-1α
    • Ventura-Clapier, R.; Garnier, A.; Veksler, V. Transcriptional control of mitochondrial biogenesis: The central role of PGC-1α. Cardiovasc. Res. 2008, 79, 208-217.
    • (2008) Cardiovasc. Res , vol.79 , pp. 208-217
    • Ventura-Clapier, R.1    Garnier, A.2    Veksler, V.3
  • 75
    • 34147109662 scopus 로고    scopus 로고
    • PGC- 1alpha regulates the neuromuscular junction program and ameliorates Duchenne muscular dystrophy
    • Handschin, C.; Kobayashi, Y.M.; Chin, S.; Seale, P.; Campbell, K.P.; Spiegelman, B.M. PGC- 1alpha regulates the neuromuscular junction program and ameliorates Duchenne muscular dystrophy. Genes Dev. 2007, 21, 770-783.
    • (2007) Genes Dev , vol.21 , pp. 770-783
    • Handschin, C.1    Kobayashi, Y.M.2    Chin, S.3    Seale, P.4    Campbell, K.P.5    Spiegelman, B.M.6
  • 77
    • 33746009957 scopus 로고    scopus 로고
    • Coordination of metabolic plasticity in skeletal muscle
    • Hood, D.A.; Irrcher, I.; Ljubicic, V.; Joseph, A.M. Coordination of metabolic plasticity in skeletal muscle. J. Exp. Bio. 2006, 209, 2265-2275.
    • (2006) J. Exp. Bio , vol.209 , pp. 2265-2275
    • Hood, D.A.1    Irrcher, I.2    Ljubicic, V.3    Joseph, A.M.4
  • 78
    • 34547545892 scopus 로고    scopus 로고
    • AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha
    • Jager, S.; Handschin, C.; St-Pierre, J.; Spiegelman, B.M. AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha. Proc. Natl. Acad. Sci. USA 2007, 104, 12017-12022.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 12017-12022
    • Jager, S.1    Handschin, C.2    St-Pierre, J.3    Spiegelman, B.M.4
  • 79
    • 38349087249 scopus 로고    scopus 로고
    • Mitochondrial function and apoptotic susceptibility in aging skeletal muscle
    • Chabi, B.; Ljubicic, V.; Menzies, K.J.; Huang, J.H.; Sallem, A.; Hood, D.A. Mitochondrial function and apoptotic susceptibility in aging skeletal muscle. Aging Cell 2008, 7, 2-12.
    • (2008) Aging Cell , vol.7 , pp. 2-12
    • Chabi, B.1    Ljubicic, V.2    Menzies, K.J.3    Huang, J.H.4    Sallem, A.5    Hood, D.A.6
  • 80
    • 49649128985 scopus 로고    scopus 로고
    • Mitochondrial biogenesis and healthy aging. Exp
    • López-Lluch, G.; Irusta, P.M.; Navas, P.; de Cabo, R. Mitochondrial biogenesis and healthy aging. Exp. Gerontol. 2008, 43, 813-819.
    • (2008) Gerontol , vol.43 , pp. 813-819
    • López-Lluch, G.1    Irusta, P.M.2    Navas, P.3    de Cabo, R.4
  • 81
    • 0344153764 scopus 로고    scopus 로고
    • Role of apoptosis in sarcopenia
    • Leeuwenburgh, C. Role of apoptosis in sarcopenia. J. Gerontol. Med. Sci. 2003, 58, 999-1001.
    • (2003) J. Gerontol. Med. Sci , vol.58 , pp. 999-1001
    • Leeuwenburgh, C.1
  • 83
    • 0033796250 scopus 로고    scopus 로고
    • Mitochondrial free radical generation, oxidative stress, and aging. Free Rad. Biol
    • Cadenas, E.; Davies, K.J. Mitochondrial free radical generation, oxidative stress, and aging. Free Rad. Biol. Med. 2000, 29, 222-230.
    • (2000) Med , vol.29 , pp. 222-230
    • Cadenas, E.1    Davies, K.J.2
  • 84
    • 33646697753 scopus 로고    scopus 로고
    • Exercise training attenuates age-induced changes in apoptotic signaling in rat skeletal muscle
    • Song, W.; Kwak, H.; Lawler, J.M. Exercise training attenuates age-induced changes in apoptotic signaling in rat skeletal muscle. Antioxid. Redox. Signal. 2006, 8, 517-528.
    • (2006) Antioxid. Redox. Signal , vol.8 , pp. 517-528
    • Song, W.1    Kwak, H.2    Lawler, J.M.3
  • 85
    • 0035127960 scopus 로고    scopus 로고
    • Resistance exercise decreases skeletal muscle tumor necrosis factor alpha in frail elderly humans
    • Greiwe, J.S.; Cheng, B.; Rubin, D.C.; Yarasheski, K.E.; Semenkovich, C.F. Resistance exercise decreases skeletal muscle tumor necrosis factor alpha in frail elderly humans. FASEB J. 2001, 15, 475-482.
    • (2001) FASEB J , vol.15 , pp. 475-482
    • Greiwe, J.S.1    Cheng, B.2    Rubin, D.C.3    Yarasheski, K.E.4    Semenkovich, C.F.5
  • 87
    • 10744228606 scopus 로고    scopus 로고
    • Endurance training in humans leads to fiber type-specific increases in levels of peroxisome proliferatoractivated receptor-gamma coactivator-1 and peroxisome proliferator-activated receptor-alpha in skeletal muscle
    • Russell, A.P.; Schreiber, S.; Crettenand, A.; Meier, C.A.; Kralli, A.; Deriaz, O. Endurance training in humans leads to fiber type-specific increases in levels of peroxisome proliferatoractivated receptor-gamma coactivator-1 and peroxisome proliferator-activated receptor-alpha in skeletal muscle. Diabetes 2003, 52, 2874-2881.
    • (2003) Diabetes , vol.52 , pp. 2874-2881
    • Russell, A.P.1    Schreiber, S.2    Crettenand, A.3    Meier, C.A.4    Kralli, A.5    Deriaz, O.6
  • 89
    • 15444374348 scopus 로고    scopus 로고
    • The anti-inflammatory effect of exercise
    • Petersen, A.M.; Pedersen, B.K. The anti-inflammatory effect of exercise. J. Appl. Physiol. 2005, 98, 1154-1162.
    • (2005) J. Appl. Physiol , vol.98 , pp. 1154-1162
    • Petersen, A.M.1    Pedersen, B.K.2
  • 90
    • 0037440667 scopus 로고    scopus 로고
    • Expression of IGF-I splice variants in young and old human skeletal muscle after high resistance exercise
    • Hameed, M.; Orrell, R.W.; Cobbold, M.; Goldspink, G.; Harridge, S.D. Expression of IGF-I splice variants in young and old human skeletal muscle after high resistance exercise. J. Physiol. 2003, 547, 247-254.
    • (2003) J. Physiol , vol.547 , pp. 247-254
    • Hameed, M.1    Orrell, R.W.2    Cobbold, M.3    Goldspink, G.4    Harridge, S.D.5
  • 91
    • 33746691931 scopus 로고    scopus 로고
    • Efficacy of 3 days/wk resistance training on myofiber hypertrophy and myogenic mechanisms in young vs. older adults
    • Kosek, D.J.; Kim, J.; Petrella, J.K.; Cross, J.M.; Bamman, M.M. Efficacy of 3 days/wk resistance training on myofiber hypertrophy and myogenic mechanisms in young vs. older adults. J. Appl. Physiol. 2006, 101, 531-544.
    • (2006) J. Appl. Physiol , vol.101 , pp. 531-544
    • Kosek, D.J.1    Kim, J.2    Petrella, J.K.3    Cross, J.M.4    Bamman, M.M.5
  • 94
    • 33750736640 scopus 로고    scopus 로고
    • Concurrent strength and endurance training: From molecules to man
    • Nader, G.A. Concurrent strength and endurance training: From molecules to man. Med. Sci. Sports Exerc. 2006, 38, 1965-1970.
    • (2006) Med. Sci. Sports Exerc , vol.38 , pp. 1965-1970
    • Nader, G.A.1
  • 95
    • 18144386162 scopus 로고    scopus 로고
    • Selective activation of AMPK-PGC-1alpha or PKB-TSC2-mTOR signaling can explain specific adaptive responses to endurance or resistance training-like electrical muscle stimulation
    • Atherton, P.J.; Babraj, J.; Smith, K.; Singh, J.; Rennie, M.J.; Wackerhage, H. Selective activation of AMPK-PGC-1alpha or PKB-TSC2-mTOR signaling can explain specific adaptive responses to endurance or resistance training-like electrical muscle stimulation. FASEB J. 2005, 19, 786-798.
    • (2005) FASEB J , vol.19 , pp. 786-798
    • Atherton, P.J.1    Babraj, J.2    Smith, K.3    Singh, J.4    Rennie, M.J.5    Wackerhage, H.6
  • 96
    • 0031260095 scopus 로고    scopus 로고
    • Caloric restriction attenuates dityrosine cross-linking of cardiac and skeletal muscle proteins in aging mice
    • Leeuwenburgh, C.; Wagner, P.; Holloszy, J.O.; Sohal, R.S.; Heinecke, J.W. Caloric restriction attenuates dityrosine cross-linking of cardiac and skeletal muscle proteins in aging mice. Arch. Biochem. Biophys. 1997, 346, 74-80.
    • (1997) Arch. Biochem. Biophys , vol.346 , pp. 74-80
    • Leeuwenburgh, C.1    Wagner, P.2    Holloszy, J.O.3    Sohal, R.S.4    Heinecke, J.W.5
  • 97
    • 2442711771 scopus 로고    scopus 로고
    • Early-onset calorie restriction conserves fiber number in aging rat skeletal muscle
    • McKiernan, S.; Bua, E.; McGorray, J.; Aiken, J. Early-onset calorie restriction conserves fiber number in aging rat skeletal muscle. FASEB J. 2004, 18, 580-581.
    • (2004) FASEB J , vol.18 , pp. 580-581
    • McKiernan, S.1    Bua, E.2    McGorray, J.3    Aiken, J.4
  • 98
    • 40849139052 scopus 로고    scopus 로고
    • Lifelong Exercise and Mild (8%) Caloric Restriction Attenuate Age-induced Alterations in Plantaris Muscle Morphology, Oxidative Stress and IGF-1 in the Fischer-344 Rat. Exp
    • Kim, J.; Kwak, H.; Leeuwenburgh C.; Lawler, J.M. Lifelong Exercise and Mild (8%) Caloric Restriction Attenuate Age-induced Alterations in Plantaris Muscle Morphology, Oxidative Stress and IGF-1 in the Fischer-344 Rat. Exp. Gerontol. 2008, 43, 317-329.
    • (2008) Gerontol , vol.43 , pp. 317-329
    • Kim, J.1    Kwak, H.2    Leeuwenburgh, C.3    Lawler, J.M.4
  • 99
    • 16844382376 scopus 로고    scopus 로고
    • Role of protein and amino acids in the pathophysiology and treatment of sarcopenia
    • Dreyer, H.C.; Volpi, E. Role of protein and amino acids in the pathophysiology and treatment of sarcopenia. J. Am. Coll. Nutr. 2005, 24, 140S-145S.
    • (2005) J. Am. Coll. Nutr , vol.24
    • Dreyer, H.C.1    Volpi, E.2
  • 101
    • 3042822477 scopus 로고    scopus 로고
    • Branched-chain amino acids increase p70S6k phosphorylation in human skeletal muscle after resistance exercise
    • Karlsson, H.K.; Nilsson, P.A.; Nilsson, J.; Chibalin, A.V.; Zierath, J.R.; Blomstrand, E. Branched-chain amino acids increase p70S6k phosphorylation in human skeletal muscle after resistance exercise. Am. J. Physiol. 2004, 287, E1-E7.
    • (2004) Am. J. Physiol , vol.287
    • Karlsson, H.K.1    Nilsson, P.A.2    Nilsson, J.3    Chibalin, A.V.4    Zierath, J.R.5    Blomstrand, E.6
  • 102
    • 33845645391 scopus 로고    scopus 로고
    • Synergistic effects of caloric restriction with maintained protein intake on skeletal muscle performance in 21-month-old rats: A mitochondria-mediated pathway
    • Zangarelli, A.; Chanseaume, E.; Morio, B.; Brugère, C.; Mosoni, L.; Rousset, P.; Giraudet, C.; Patrac, V.; Gachon, P.; Boirie, Y.; et al. Synergistic effects of caloric restriction with maintained protein intake on skeletal muscle performance in 21-month-old rats: A mitochondria-mediated pathway. FASEB J. 2006, 20, 2439-2450.
    • (2006) FASEB J , vol.20 , pp. 2439-2450
    • Zangarelli, A.1    Chanseaume, E.2    Morio, B.3    Brugère, C.4    Mosoni, L.5    Rousset, P.6    Giraudet, C.7    Patrac, V.8    Gachon, P.9    Boirie, Y.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.