Analysis of the thiol status of peripheral blood leukocytes in rheumatoid arthritis patients

Journal of Leukocyte Biology

Volumn 81, Issue 4, 2007, Pages 934-941

  Pedersen Lane, Joan H ^a   Zurier, Robert B ^b   Lawrence, David A ^a  

^a WADSWORTH CENTER   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

CD53; Flow cytometry; Glutathione; Telomeres

Indexed keywords

CD19 ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; CD53 ANTIGEN; CD8 ANTIGEN; GAMMA GLUTAMYLTRANSFERASE; GLUTATHIONE; LEUKOSIALIN; REACTIVE OXYGEN METABOLITE; THIOL DERIVATIVE;

ADULT; AGED; ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; CELL AGING; CELL PROTECTION; DISEASE CLASSIFICATION; ENZYME ANALYSIS; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LEUKOCYTE; LONGEVITY; LYMPHOCYTE; MALE; NATURAL KILLER CELL; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; RHEUMATOID ARTHRITIS; TELOMERE;

ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; ARTHRITIS, RHEUMATOID; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CELL MEMBRANE; CHRONIC DISEASE; FEMALE; HUMANS; LEUKOCYTES; MALE; MIDDLE AGED; SULFHYDRYL COMPOUNDS; TELOMERE;

EID: 33947683316     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0806533     Document Type: Article

References (56)

1. Firestein, G. S. (2003) Evolving concepts of rheumatoid arthritis. Nature 423, 356-361.
2. Goronzy, J. J., Weyand, C. M. (2005) Rheumatoid arthritis. Immunol. Rev. 204, 55-73.
3. Darlington, L. G., Stone, T. W. (2001) Antioxidants and fatty acids in the amelioration of rheumatoid arthritis and related disorders. Br. J. Nutr. 85, 251-269.
4. Winyard, P. G., Moody, C. J., Jacob, C. (2005) Oxidative activation of antioxidant defense. Trends Biochem. Sci. 30, 453-461.
5. Dröge, W. (2002) Free radicals in the physiological control of cell function. Physiol. Rev. 82, 47-95.
6. Dickinson, D. A., Forman, H. J. (2002) Cellular glutathione and thiols metabolism. Biochem. Pharmacol. 64, 1019-1026.
7. Cuozzo, J. W., Kaiser, C. A. (1999) Competition between glutathione and protein thiols for disulfide-bond formation. Nat. Cell Biol. 1, 130-135.
8. Deneke, S. M. (2000) Thiol-based antioxidants. Curr. Top. Cell. Regul. 36, 151-180.
9. Remans, P. H. J., van Oosterhout, M., Smeets, T. J. M., Sanders, M., Frederiks, W. M., Reesquist, K. A., Tak, P. P., Breedveld, F. C., van Laar, J. M. (2005) Intracellular free radical production in synovial T lymphocytes from patients with rheumatoid arthritis. Arthritis Rheum. 52, 2003-2009.
10. Brown-Galatola, C. H., Hall, N. D. (1992) Impaired suppressor cell activity to surface sulfydryl oxidation in rheumatoid arthritis. Br. J. Rheumatol. 31, 599-603.
11. Lawrence, D. A., Song, R., Weber, P. (1996) Surface thiols in human lymphocytes and their changes after in vitro and in vivo activation. J. Leukoc. Biol. 60, 611-618.
12. Kanner, S. B., Kvanagh, T. J., Grossmann, A., Hu, S-L., Bolen, J. B., Rabinovitch, P. S., Ledbetter, J. (1992) Sulfhydryl oxidation down-regulates T-cell signaling and inhibits tyrosine phosphorylation of phospholipase Cγ1. Proc. Natl. Acad. Sci. USA 89, 300-304.
13. Hanigan, M. H., Ricketts, W. A. (1993) Extracellular glutathione is a source of cysteine for cells that express γ-glutamyl transpeptidase. Biochemistry 32, 6302-6306.
14. Carlisle, M. L., King, M. R., Karp, D. R. (2003) γ-Glutamyl transpeptidase activity alters the T cell response to oxidative stress and FAS-induced apoptosis. Int. Immunol. 15, 17-27.
15. Nichols, T. C., Guthridge, J. M., Karp, D. R., Molina, H., Fletcher, D. R., Holers, V. M. (1998) γ-Glutamyl transpeptidase, an ecto-enzyme regulator of intracellular redox potential, is a component of TM4 signal transduction complexes. Eur. J. Immunol. 28, 4123-4129.
16. Maecker, H. T., Todd, S. C., Levy, S. (1997) The tetraspanin superfamily: molecular facilitators. FASEB J. 11, 428-442.
17. Kim, T-R., Yoon, J-H., Kim, Y-C., Yook, Y-H., Kim, I-G., Kim, Y-S., Lee, H., Paik, S-G. (2004) LPS-induced CD53 expression: a protection mechanism against oxidative and radiation stress. Mol. Cells 17, 125-131.
18. Voehringer, D. W., Hircschberg, D. L., Xiao, J., Roederer, M., Lock, C. B., Herzenberg, L. A., Steinman, L., Herzenberg, L. A. (2000) Gene microarray identification of redox and mitochondrial elements that control resistance or sensitivity to apoptosis. Proc. Natl. Acad. Sci. USA 97, 2680-2685.
19. Yunta, M., Lazo, P. A. (2003) Apoptosis protection and survival signal by the CD53 tetraspanin antigen. Oncogene 22, 1219-1224.
20. Liu, H., Pope, R. M. (2003) The role of apoptosis in rheumatoid arthritis. Curr. Opin. Pharmacol. 3, 317-322.
21. Epel, E. S., Balckburn, E. H., Lin, J., Dhabhar, F. S., Adler, N. E., Morrow, J. D., Cawthon, R. M. (2004) Accelerated telomere shortening in response to life stress. Proc. Natl. Acad. Sci. USA 101, 17312-17315.
22. Goronzy, J. J., Fujii, H., Weyand, C. M. (2006) Telomeres, immune aging and autoimmunity. Exp. Gerontol. 41, 246-251.
23. Kurz, D. J., Decary, S., Hong, Y., Trivier, E., Akhmedov, A., Eruslimsky, J. D. (2004) Chronic oxidative stress compromises telomere integrity and accelerates the onset of senescence in human endothelial cells. J. Cell Sci. 117, 2417-2426.
24. Townsend, D. M., Tew, K. D., Tapiero, H. (2003) The importance of glutathione in human disease. Biomed. Pharmacother. 57, 145-155.
25. Franceschi, C., Bonafè, M. (2003) Centenarians as a model for healthy aging. Biochem. Soc. Trans. 31, 457-461.
26. Hochberg, M. C., Chang, R. W., Dwosh, I., Lindsey, S., Pincus, T., Wolfe, F. (1992) The American College of Rheumatology 1991 revised criteria for the classification of global functional status in rheumatoid arthritis. Arthritis Rheum. 35, 498-502.
27. Messina, J. P., Mazurkiewicz, J., Lawrence, D. A. (1987) Production and characterization of monoclonal antibodies to thiol-modified glutathione. In Anticarcinogenesis and Radiation Protection (P. A. Cerutti, M. G. Nygaard, M. G. Simic, eds.), New York, NY, USA, Plenum, 407-412.
28. Ault, J. G., Lawrence, D. A. (2003) Glutathione distribution in normal and oxidatively stressed cells. Exp. Cell Res. 285, 9-14.
29. Kapoor, V., Telford, W. G. (2004) Telomere length measurement by fluorescence in situ hybridization and flow cytometry. In Methods in Molecular Biology: Flow Cytometry Protocols, 2nd ed. (T. S. Hawley, R. G. Hawley, eds.), Totowa, NJ, USA, Humana. pp. 385-398.
30. Donoghue, N., Yam, P. T. W., Jiang, X-M., Hogg, P. (2000) Presence of closely spaced protein thiols on the surface of mammalian cells. Protein Sci. 9, 2436-2445.
31. Duncan, D. D., Lawrence, D. A. (1991) Residual activation events functional after irradiation of mouse splenic lymphocytes. Radiat. Res. 125, 6-13.
32. Duncan, D. D., Lawrence, D. A. (1988) Four sulfhydryl-modifying compounds cause different structural damage but similar functional damage in murine lymphocytes. Chem. Biol. Interact. 68, 137-152.
33. Finkel, T., Holbrook, N. J. (2000) Oxidants, oxidative stress and the biology of aging. Nature 408, 239-247.
34. Härle, P., Straub, R. H. (2005) Neuroendocrine-immune aspects of accelerated aging in rheumatoid arthritis. Curr. Rheumatol. Rep. 7, 389-394.
35. Dröge, W., Breitkreutz, R. (2000) Glutathione and immune function. Proc. Nutr. Soc. 59, 595-600.
36. Roederer, M., Staal, F. J. T., Osada, H., Herzenberg, L. A., Herzenberg, L. A. (1991) CD4 and CD8 cells with high intracellular glutathione levels are selectively lost as the HIV infection progresses. Int. Immunol. 3, 933-937.
37. Tohami, T., Drucker, L., Radnay, J., Shapira, H., Lishner, M. (2004) Expression of tetraspanins in peripheral blood leukocytes: a comparison between normal and infectious conditions. Tissue Antigens 64, 235-242.
38. Koetz, K., Bryl, E., Spickschen, K., O'Fallon, W. M., Goronzy, J. J., Weyand, C. M. (2000) T cell homeostasis in patients with rheumatoid arthritis. Proc. Natl. Acad. Sci. USA 97, 9203-9208.
39. Castro, L., Freeman, B. A. (2001) Reactive oxygen species in human health and disease. Nutrition 17, 161-165.
40. Lunec, J., Halloran, S. P., White, A. G., Dormandy, T. L. (1981) Freeradical oxidation (peroxidation) products in serum and synovial fluid in rheumatoid arthritis. J. Rheumatol. 8, 233-245.
41. Gambhir, J. K., Lali, P., Jain, A. L. (1997) Correlation between blood antioxidant levels and lipid peroxidation in rheumatoid arthritis. Clin. Biochem. 30, 351-355.
42. Giustarini, D., Lorenzini, S., Rossi, R., Chindamo, D., DiSimplicio, P., Marcolongo, R. (2005) Altered thiol patterns in plasma of subjects affected by rheumatoid arthritis. Clin. Exp. Rheumatol. 23, 205-212.
43. Halliwell, B., Gutteridge, J. M. (1990) The antioxidants of human extracellular fluids. Arch. Biochem. Biophys. 280, 1-8.
44. Sahaf, B., Heydrai, K., Herzenberg, L. A., Herzenberg, L. A. (2005) The extracellular microenvironment plays a key role in regulating the redox status of cell surface proteins in HIV-infected subjects. Arch. Biochem. Biophys. 434, 26-32.
45. Meister, A. (1988) Glutathione metabolism and its selective modification. J. Biol. Chem. 263, 17205-17208.
46. Roozendaal, R., Vellenga, E., de Jong, M. A., Traanberg, K. F., Postma, D. S., de Monchy, J. G. R., Kauffman, H. F. (2001) Resistance of activated human Th2 cells to NO-induced apoptosis is mediated by γ-glutamyl transpeptidase. Int. Immunol. 13, 519-528.
47. Del Bello, B., Paolicchi, A., Comporti, M., Pompella, A., Maellaro, E. (1999) Hydrogen peroxide produced during γ-glutamyl transpeptidase activity is involved in prevention of apoptosis and maintenance of proliferation in U937 cells. FASEB J. 13, 69-79.
48. Pope, R. M. (2002) Apoptosis as a therapeutic tool in rheumatoid arthritis. Nat. Rev. Immunol. 2, 527-535.
49. Peng, S. L. (2006) FAS (CD95)-related apoptosis and rheumatoid arthritis. Rheumatology (Oxford) 45, 26-30.
50. Liu, H., Pope, R. (2004) Apoptosis in rheumatoid arthritis: friend or foe. Rheum. Dis. Clin. North Am. 30, 603-625.
51. Leppa, S., Bohmann, D. (1999) Diverse functions of JNK signaling and c-Jun in stress response and apoptosis. Oncogene 18, 6158-6162.
52. Lazo, P. A., Cuevas, L., Gutierrez del Arroyo, A., Orue, E. (1997) Ligation of CD53/OX44, a tetraspan antigen, induces homotypic adhesion mediated by specific cell-cell interactions. Cell. Immunol. 178, 132-140.
53. Sarkar, D., Fisher, P. B. (2006) Molecular mechanisms of aging-associated inflammation. Cancer Lett. 236, 13-23.
54. Von Zglinicki, T., Martin-Ruiz, C. M. (2005) Telomeres as biomarkers for ageing and age-related diseases. Curr. Mol. Med. 5, 197-203.
55. Saretzki, G., von Zglinicki, T. (2002) Replicative aging, telomeres, and oxidative stress. Ann. N. Y. Acad. Sci. 959, 24-29.
56. Schönland, S. O., Lopez, C., Wildman, T., Zimmer, J., Bryl, E., Goronsky, J. J., Weyand, C. M. (2003) Premature telomeric loss in rheumatoid arthritis is genetically determined and involves both myeloid and lymphoid cell lineages. Proc. Natl. Acad. Sci. USA 100, 13471-13476.