Oxysterols exert proinflammatory effects in placental trophoblasts via TLR4-dependent, cholesterol-sensitive activation of NF-κB

Molecular Human Reproduction

Volumn 18, Issue 7, 2012, Pages 341-353

  Aye, Irving L M H ^a   Waddell, Brendan J ^b   Mark, Peter J ^b   Keelan, Jeffrey A ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

25 hydroxycholesterol; 7 ketocholesterol; Cholesterol; Cytokines (IL 6, TNF , MIP 1 ); Nuclear factor kappa B

Indexed keywords

25 HYDROXYCHOLESTEROL; 7 OXOCHOLESTEROL; CHOLESTEROL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; N (2,2,2 TRIFLUOROETHYL) N [4 [2,2,2 TRIFLUORO 1 HYDROXY 1 (TRIFLUOROMETHOXY)ETHYL]PHENYL]BENZENESULFONAMIDE; PARTHENOLIDE; TOLL LIKE RECEPTOR 4;

ARTICLE; ENZYME PHOSPHORYLATION; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; NUCLEAR LOCALIZATION SIGNAL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TROPHOBLAST;

CELLS, CULTURED; CHEMOKINE CCL4; FEMALE; HUMANS; HYDROXYCHOLESTEROLS; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-6; KETOCHOLESTEROLS; LIPOPOLYSACCHARIDES; NF-KAPPA B; PREGNANCY; TROPHOBLASTS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84863753420     PISSN: 13609947     EISSN: 14602407     Source Type: Journal    
DOI: 10.1093/molehr/gas001     Document Type: Article

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