Oxysterols inhibit differentiation and fusion of term primary trophoblasts by activating liver X receptors

Placenta

Volumn 32, Issue 2, 2011, Pages 183-191

  Aye, I L M H ^a   Waddell, B J ^b   Mark, P J ^b   Keelan, J A ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

22(R) hydroxycholesterol; 25 Hydroxycholesterol; 7 Ketocholesterol; Differentiation; Fusion; LXR; Nuclear receptor; Oxysterols; Placenta; Syncytialisation

Indexed keywords

22 HYDROXYCHOLESTEROL; 25 HYDROXYCHOLESTEROL; 7 OXOCHOLESTEROL; ALKALINE PHOSPHATASE; ALKALINE PHOSPHATASE PLACENTA ISOENZYME; CHOLESTEROL DERIVATIVE; CHORIONIC GONADOTROPIN; GERANYLGERANYL PYROPHOSPHATE; LIPID; LIVER X RECEPTOR; MESSENGER RNA; N (2,2,2 TRIFLUOROETHYL) N [4 [2,2,2 TRIFLUORO 1 HYDROXY 1 (TRIFLUOROMETHOXY)ETHYL]PHENYL]BENZENESULFONAMIDE; UVOMORULIN;

ARTICLE; BIOLOGICAL ACTIVITY; BLAST CELL; CELL CULTURE; CELL DIFFERENTIATION; CELL FUSION; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; FIRST TRIMESTER PREGNANCY; HOMEOSTASIS; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER; NORMAL HUMAN; PLACENTA; PRIORITY JOURNAL; PROTEIN SECRETION; REGULATORY MECHANISM; TROPHOBLAST;

ALKALINE PHOSPHATASE; CELL DIFFERENTIATION; CELL FUSION; CHORIONIC GONADOTROPIN; FEMALE; GENE PRODUCTS, ENV; HUMANS; HYDROCARBONS, FLUORINATED; HYDROXYCHOLESTEROLS; KETOCHOLESTEROLS; NUCLEAR PROTEINS; ORPHAN NUCLEAR RECEPTORS; PLACENTA; PREGNANCY; PREGNANCY PROTEINS; RNA, MESSENGER; SULFONAMIDES; TRANSCRIPTION FACTORS; TROPHOBLASTS;

EID: 79951512765     PISSN: 01434004     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.placenta.2010.12.007     Document Type: Article

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