Placental ABCA1 and ABCG1 transporters efflux cholesterol and protect trophoblasts from oxysterol induced toxicity

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1801, Issue 9, 2010, Pages 1013-1024

  Aye, Irving L M H ^a   Waddell, Brendan J ^b   Mark, Peter J ^b   Keelan, Jeffrey A ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

ABCA1; ABCG1; Cholesterol; LXR; Oxysterol; Placenta

Indexed keywords

25 HYDROXYCHOLESTEROL; 7 OXOCHOLESTEROL; ABC TRANSPORTER A1; ABC TRANSPORTER G1; APOLIPOPROTEIN A1; CHOLESTEROL; GLIBENCLAMIDE; HIGH DENSITY LIPOPROTEIN; N (2,2,2 TRIFLUOROETHYL) N [4 [2,2,2 TRIFLUORO 1 HYDROXY 1 (TRIFLUOROMETHOXY)ETHYL]PHENYL]BENZENESULFONAMIDE; OXYSTEROL; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; SMALL INTERFERING RNA; 25-HYDROXYCHOLESTEROL; 7-KETOCHOLESTEROL; ABC TRANSPORTER; ABCA1 PROTEIN, HUMAN; ABCG1 PROTEIN, HUMAN; CHOLESTEROL DERIVATIVE; ENZYME INHIBITOR; MESSENGER RNA;

APOPTOSIS; ARTICLE; BASOLATERAL MEMBRANE; CELL MEMBRANE TRANSPORT; CELL PROTECTION; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SYNCYTIOTROPHOBLAST; TROPHOBLAST; ANTAGONISTS AND INHIBITORS; CELL PROLIFERATION; DRUG EFFECTS; ENZYME IMMUNOASSAY; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; METABOLISM; PLACENTA; PREGNANCY; TRANSPORT AT THE CELLULAR LEVEL; WESTERN BLOTTING;

ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL TRANSPORT; BLOTTING, WESTERN; CELL PROLIFERATION; CHOLESTEROL; ENZYME INHIBITORS; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; HYDROXYCHOLESTEROLS; IMMUNOENZYME TECHNIQUES; KETOCHOLESTEROLS; PLACENTA; PREGNANCY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; TROPHOBLASTS; ATP BINDING CASSETTE TRANSPORTER 1;

EID: 77954660372     PISSN: 13881981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbalip.2010.05.015     Document Type: Article

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