Role of adapters in Toll-like receptor signalling

Biochemical Society Transactions

Volumn 31, Issue 3, 2003, Pages 637-642

  Akira, S ^a   Yamamoto, M ^a   Takeda, K ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

Immune response; Interferon; Interleukin; Myd88; Signal transduction; Toll like receptor (TLR)

Indexed keywords

ADAPTOR PROTEIN; ADAPTOR PROTEIN MYD88; ALPHA INTERFERON; ANTIVIRUS AGENT; BETA INTERFERON; CD40 ANTIGEN; COMPLEMENTARY DNA; CYTOKINE; CYTOSINE; DNA; DOUBLE STRANDED RNA; FLAGELLIN; GUANINE; IMIDAZOQUINOLINE DERIVATIVE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE; INTERLEUKIN 12; LIPOPOLYSACCHARIDE; LIPOPROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PEPTIDOGLYCAN; TIR DOMAIN CONTAINING ADAPTER INDUCING INTERFERON BETA; TIR DOMAIN CONTAINING ADAPTER PROTEIN; TOLL LIKE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL MODEL; CONFERENCE PAPER; CPG ISLAND; ENZYME ACTIVATION; GENE INDUCTION; IMMUNE RESPONSE; INFLAMMATION; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTIGENS, DIFFERENTIATION; CELL DIFFERENTIATION; LIPOPOLYSACCHARIDES; MAMMALS; MEMBRANE GLYCOPROTEINS; MUSCLE, SKELETAL; MYELOID DIFFERENTIATION FACTOR 88; RECEPTORS, CELL SURFACE; RECEPTORS, IMMUNOLOGIC; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTORS;

ANIMALIA;

EID: 0038202226     PISSN: 03005127     EISSN: None     Source Type: Journal    
DOI: 10.1042/BST0310637     Document Type: Conference Paper

References (36)

1. Akira, S., Takeda, K. and Kaisho, T. (2001) Nat. Immunol. 2, 675-680
2. Aderem, A. and Ulevitch, R.J. (2000) Nature (London) 406, 782-787
3. Janeway, Jr, C.A. and Medzhitov, R. (2002) 20, 197-216.
4. Poltorak, A., He, X., Smirnova, I., Liu, M.Y., Huffel, C.V., Du, X., Birdwell, O., Alejos, E., Silva, M., Galanos, C. et al. (1998) Science 282, 2085-2088
5. Hoshino, K., Takeuchi, O., Kawai, T., Sanjo, H., Ogawa, T., Takeda, Y., Takeda, K. and Akira, S. (1999) J. Immunol. 162, 3749-3752
6. Shimazu, R., Akashi, S., Ogata, H., Nagai, Y., Fukudome, K., Miyake, K. and Kimoto, M. (1999) J. Exp Med. 189, 1777-1782
7. Brightbill, H.D., Libraty, D.H., Krutzik, S.R., Yang, R.-B., Belisle, J.T., Bleharski, J.R., Maitland, M., Norgard, M.V., Plevy, S.E., Smale, S.T. et al. (1999) Science 285, 32-36
8. Aliprantis, A.O., Yang, R.-B., Mark, M.R., Suggett, S., Devaux, B., Radolf, J.D., Klimpel, G.R., Godowski, P. and Zychlinsky, A. (1999) Science 285, 736-739
9. Takeuchi, O., Hoshino, K., Kawai, T., Sanjo, H, Takada, H., Ogawa, T., Takeda, K. and Akira, S. (1999) Immunity 11, 443-451
10. Hirschfeld, M., Kirschning, C.J., Schwandner, R., Wesche, H., Weis, J.H., Wooten, R.M. and Weis, J.J. (1999) J. Immunol. 163, 2382-2386
11. Takeuchi, O., Kaufmann, A., Grote, K., Kawai, T., Hoshino, K., Morr, M., Muhlradt, P.F. and Akira, S. (2000) J. Immunol. 164, 554-557
12. Campos, M.A., Almeida, I.C, Takeuchi, O., Akira, S., Valente, E.P., Procopio, D.O., Travassos, L.R., Smith, J.A., Golenbock, D.T. and Gazzinelli, R.T. (2001) J. Immunol. 167, 416-423
13. Underhill, D.M., Ozinsky, A., Hajjar, A.M., Stevens, A., Wilson, C.B., Bassetti, M. and Aderem, A. (1999) Nature (London) 401, 811-815
14. Ozinsky, A., Underhill, D.M., Fontenot, J.D., Hajjar, A.M., Smith, K.D., Wilson, C.B., Schroeder, L. and Aderem, A. Proc. Natl. Acad Sci. U.S.A. 97, 13766-13771
15. Takeuchi, O., Kawai, T., Muhlradt, P.F., Radolf, J.D., Zychlinsky, A., Takeda, K. and Akira, S. (2001) Int. Immunol. 13, 933-940
16. Takeuchi, O., Sato, S., Horiuchi, T., Hoshino, K., Takeda, K., Dong, Z., Modlin, R.L. and Akira, S. (2002) J. Immunol. 169, 10-14
17. Hemmi, H., Takeuchi, O., Kawai, T., Kaisho, T., Sato, S., Sanjo, H., Matsumoto, M., Hoshino, K., Wagner, H., Takeda, K. and Akira, S. (2000) Nature (London) 408, 740-745
18. Hayashi, F., Smith, K.D., Ozinsky, A., Hawn, T.R., Yi, E.C., Goodlett, D.R., Eng, J.K., Akira, S., Underhill, D.M. and Aderem, A. (2001) Nature (London) 410, 1099-1103
19. Alexopoulou, L., Holt, A.C., Medzhitov, R. and Flavell, R.A. (2001) Nature (London) 413, 732-738
20. Hemmi, H., Kaisho, T., Takeuchi, O., Sato, S., Sanjo, H., Hoshino, K., Horiuchi, T., Tomizawa, H., Takeda, K. and Akira, S. (2002) Nat. Immunol. 3, 196-200
21. Lord, K.A., Hoffman-Liebermann, B. and Liebermann, D.A. (1990) Oncogene 5, 1095-1097
22. Hultmark, D. (1994) Biochem. Biophys. Res. Commun. 199, 144-146
23. Wesche, H., Henzel, W.J., Shillinglaw, W., Li, S. and Cao, Z. (1997) Immunity 7, 837-847
24. Muzio, M., Ni, J., Feng, P. and Dixit, V.M. (1997) Science 278, 1612-1615
25. Adachi, O., Kawai, T., Takeda, K., Matsumoto, M., Tsutsui, H., Sakagami, M., Nakanishi, K. and Akira, S. (1998) Immunity 9, 143-150
26. Kawai, T., Adachi, O., Ogawa, T., Takeda, K. and Akira, S. (1999) Immunity 11, 115-122
27. Kawai, T., Takeuchi, O., Fujita, T., Inoue, J., Muhlradt, P.F., Sato, S., Hoshino, K. and Akira, S. (2001) J. Immunol. 167, 5887-5894
28. Toshchakov, V., Jones, B.W., Perera, P.Y., Thomas, K., Cody, M.J., Zhang, S., Williams, B.R., Major, J., Hamilton, T.A., Fenton, M.J. and Vogel, S.N. (2002) Nat. Immunol. 3, 392-398
29. Hoshino, K., Kaisho, T., Iwabe, T., Takeuchi, O. and Akira, S. (2002) Int. Immunol. 14, 1225-1231
30. Hiscott, J., Pitha, P., Genin, P., Nguyen, H., Heylbroeck, C., Mamane, Y., Algarte, M. and Lin, R. (1999) J. Interferon Cytokine Res. 19, 1-13
31. Kaisho, T., Takeuchi, O., Kawai, T., Hoshino, K. and Akira, S. (2001) J. Immunol. 166, 5688-5694
32. Horng, T., Barton, G.M. and Medzhitov, R. (2001) Nat. Immunol. 2, 835-841
33. Fitzgerald, K.A., Palsson-McDermott, E.M., Bowie, A.G., Jefferies, C., Mansell, A.S., Brady, G., Brint, E., Dunne, A., Gray, P., Harte, M.T. et al. (2001) Nature (London) 413, 78-83
34. Yamamoto, M., Sato, S., Hemmi, H., Sanjo, H., Uematsu, S., Kaisho, T., Hoshino, K., Takeuchi, O., Kobayashi, M., Fujita, T. et al. (2002) Nature (London) 420, 324-329
35. Horng, T., Barton, G.M., Flavell, R.A. and Medzhitov, R. (2002) Nature (London) 420, 329-333
36. Yamamoto, M., Sato, S., Mori, K., Takeuchi, O., Hoshino, K., Takeda, K. and Akira, S. (2002) J. Immunol. 169, 6668-6672