LXR-activating oxysterols induce the expression of inflammatory markers in endothelial cells through LXR-independent mechanisms

Atherosclerosis

Volumn 207, Issue 1, 2009, Pages 38-44

  Morello, Fulvio ^a   Saglio, Elisa ^a   Noghero, Alessio ^b   Schiavone, Domenica ^a   Williams, Tracy Ann ^a   Verhovez, Andrea ^a   Bussolino, Federico ^b   Veglio, Franco ^a   Mulatero, Paolo ^a  

^a MOLINETTE HOSPITAL   (Italy)

^b CANDIOLO CANCER INSTITUTE   (Italy)

Author keywords

Endothelium; Inflammation; LXR; Oxysterols

Indexed keywords

22 HYDROXYCHOLESTEROL; 24,25 EPOXYCHOLESTEROL; 25 HYDROXYCHOLESTEROL; 26 HYDROXYCHOLESTEROL; 3 [3 [[2 CHLORO 3 (TRIFLUOROMETHYL)BENZYL](2 DIPHENYLETHYL)AMINO]PROPOXY]PHENYLACETIC ACID; CELL ADHESION MOLECULE; CHOLESTEROL; CYTOKINE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; INTERCELLULAR ADHESION MOLECULE 1; LIPOPOLYSACCHARIDE; LIVER X RECEPTOR AGONIST; LIVER X RECEPTOR ALPHA; LIVER X RECEPTOR BETA; N (2,2,2 TRIFLUOROETHYL) N [4 [2,2,2 TRIFLUORO 1 HYDROXY 1 (TRIFLUOROMETHOXY)ETHYL]PHENYL]BENZENESULFONAMIDE; OXYSTEROL; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

APOPTOSIS; ARTICLE; CELL INTERACTION; CONTROLLED STUDY; DOWN REGULATION; DRUG SAFETY; ENDOTHELIUM CELL; GENE EXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; LEUKOCYTE; MICROARRAY ANALYSIS; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; UPREGULATION;

ANTICHOLESTEREMIC AGENTS; BENZOIC ACIDS; BENZYLAMINES; CELLS, CULTURED; CHEMOKINES; CHOLESTEROL; E-SELECTIN; ENDOTHELIAL CELLS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; HYDROCARBONS, FLUORINATED; HYDROXYCHOLESTEROLS; INFLAMMATION MEDIATORS; INTERCELLULAR ADHESION MOLECULE-1; LIPOPOLYSACCHARIDES; ORPHAN NUCLEAR RECEPTORS; RNA INTERFERENCE; RNA, MESSENGER; SIGNAL TRANSDUCTION; SULFONAMIDES; TRANSCRIPTION FACTORS; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR CELL ADHESION MOLECULE-1;

EID: 70350570592     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2009.04.001     Document Type: Article

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