Lycopene prevention of oxysterol-induced proinflammatory cytokine cascade in human macrophages: Inhibition of NF-κB nuclear binding and increase in PPARγ expression

Journal of Nutritional Biochemistry

Volumn 22, Issue 3, 2011, Pages 259-268

  Palozza, Paola ^a   Simone, Rossella ^a   Catalano, Assunta ^a   Monego, Giovanni ^a   Barini, Angela ^a   Mele, Maria Cristina ^a   Parrone, Nadia ^b   Trombino, Sonia ^b   Picci, Nevio ^b   Ranelletti, Franco O ^a  

^a CATHOLIC UNIVERSITY   (Italy)

^b UNIVERSITY OF CALABRIA   (Italy)

Author keywords

Lycopene; NF B; Oxysterols; PPAR ; Pro inflammatory cytokine cascade; ROS

Indexed keywords

25 HYDROXYCHOLESTEROL; 7 KETO CHOLESTEROL; DIHYDROPTERIDINE REDUCTASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LYCOPENE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OXYSTEROL; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; DRUG MECHANISM; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; MACROPHAGE; PROTEIN EXPRESSION;

CAROTENOIDS; CELL LINE; CYTOKINES; HUMANS; HYDROXYCHOLESTEROLS; INTERLEUKIN-1BETA; INTERLEUKIN-6; INTERLEUKIN-8; KETOCHOLESTEROLS; MACROPHAGES; MITOGEN-ACTIVATED PROTEIN KINASES; NADPH OXIDASE; NF-KAPPA B; PHOSPHORYLATION; PLAQUE, ATHEROSCLEROTIC; PPAR GAMMA; PROTEIN BINDING; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

LYCOPERSICON ESCULENTUM;

EID: 79951669719     PISSN: 09552863     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2010.02.003     Document Type: Article

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