Macrophage ABCA1 reduces MyD88-dependent toll-like receptor trafficking to lipid rafts by reduction of lipid raft cholesterol

Journal of Lipid Research

Volumn 51, Issue 11, 2010, Pages 3196-3206

  Zhu, Xuewei ^a   Owen, John S ^a   Wilson, Martha D ^a   Li, Haitao ^b   Griffiths, Gary L ^b   Thomas, Michael J ^a   Hiltbold, Elizabeth M ^a   Fessler, Michael B ^c   Parks, John S ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^c NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Cytokines; Free cholesterol; Immunology; Lipid droplets; Lymphocytes; Retinoids

Indexed keywords

ABC TRANSPORTER A1; CAVEOLIN 1; CD14 ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 9;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CPG ISLAND; FLOW CYTOMETRY; GENE DELETION; GENE MUTATION; IMMUNOBLOTTING; IMMUNOPRECIPITATION; IN VITRO STUDY; IN VIVO STUDY; LIPID ANALYSIS; LIPID RAFT; LIPIDOMICS; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN TRANSPORT;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CHOLESTEROL; GENE DELETION; INFLAMMATION; LIPOPOLYSACCHARIDES; MACROPHAGES; MEMBRANE MICRODOMAINS; MICE; MICE, INBRED C57BL; MYELOID DIFFERENTIATION FACTOR 88; NF-KAPPA B; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTOR 9; TOLL-LIKE RECEPTORS;

EID: 78149355932     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M006486     Document Type: Article

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