Central role of the EGF receptor in neurometabolic aging

International Journal of Endocrinology

Volumn 2012, Issue , 2012, Pages

  Siddiqui, Sana ^a   Fang, Meng ^a   Ni, Bin ^a   Lu, Daoyuan ^a   Martin, Bronwen ^a   Maudsley, Stuart ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; CARCINOEMBRYONIC ANTIGEN RELATED CELL ADHESION MOLECULE 1; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; GONADORELIN; GROWTH HORMONE; INSULIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE C; SOMATOMEDIN C; TAU PROTEIN; TRANSFORMING GROWTH FACTOR ALPHA;

AGING; ALZHEIMER DISEASE; CARDIOVASCULAR DISEASE; CELL STRESS; CELL TYPE; DIABETES MELLITUS; DISEASE ASSOCIATION; FEMALE INFERTILITY; HUMAN; MALIGNANT NEOPLASTIC DISEASE; METABOLIC SYNDROME X; NERVE CELL DEGENERATION; NEUROENDOCRINOLOGY; NONHUMAN; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIATION EXPOSURE; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; RESPIRATORY TRACT DISEASE; REVIEW; SIGNAL TRANSDUCTION;

EID: 84863696631     PISSN: 16878337     EISSN: 16878345     Source Type: Journal    
DOI: 10.1155/2012/739428     Document Type: Review

References (185)

1. Zwick E., Hackel P. O., Prenzel N., Ullrich A., The EGF receptor as central transducer of heterologous signalling systems Trends in Pharmacological Sciences 1999 20 10 408 412 (Pubitemid 29450362)
2. Hackel P. O., Zwick E., Prenzel N., Ullrich A., Epidermal growth factor receptors: critical mediators of multiple receptor pathways Current Opinion in Cell Biology 1999 11 2 184 189 (Pubitemid 29164032)
3. Sorkina T., Bild A., Tebar F., Sorkin A., Clathrin, adaptors and eps15 in endosomes containing activated epidermal growth factor receptors Journal of Cell Science 1999 112 3 317 327 (Pubitemid 29080654)
4. Levkowitz G., Waterman H., Ettenberg S. A., Katz M., Tsygankov A. Y., Alroy I., Lavi S., Iwai K., Reiss Y., Ciechanover A., Lipkowitz S., Yarden Y., Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1 Molecular Cell 1999 4 6 1029 1040 (Pubitemid 30054908)
5. Ettenberg S. A., Rubinstein Y. R., Banerjee P., Nau M. M., Keane M. M., Lipkowitz S., cbl-b inhibits EGF-receptor-induced apoptosis by enhancing ubiquitination and degradation of activated receptors Molecular Cell Biology Research Communications 1999 2 2 111 118 (Pubitemid 129532315)
6. Martin B., Brenneman R., Golden E., Walent T., Becker K. G., Prabhu V. V., Wood W., Ladenheim B., Cadet J. L., Maudsley S., Growth factor signals in neural cells: coherent patterns of interaction control multiple levels of molecular and phenotypic responses Journal of Biological Chemistry 2009 284 4 2493 2511
7. Cooper J. A., Howell B., The when and how of Src regulation Cell 1993 73 6 1051 1054 (Pubitemid 23180479)
8. Hubbard S. R., Wei L., Ellis L., Hendrickson W. A., Crystal structure of the tyrosine kinase domain of the human insulin receptor Nature 1994 372 6508 746 754
9. Biscardi J. S., Maa M. C., Tice D. A., Cox M. E., Leu T. H., Parsons S. J., C-Src-mediated phosphorylation of the epidermal growth factor receptor on Tyr845 and Tyr1101 is associated with modulation of receptor function Journal of Biological Chemistry 1999 274 12 8335 8343
10. Emlet D. R., Moscatello D. K., Ludlow L. B., Wong A. J., Subsets of epidermal growth factor receptors during activation and endocytosis Journal of Biological Chemistry 1997 272 7 4079 4086 (Pubitemid 27078471)
11. Rojas M., Yao S., Lint Y. Z., Controlling epidermal growth factor (EGF)-stimulated Ras activation in intact cells by a cell-permeable peptide mimicking phosphorylated EGF receptor Journal of Biological Chemistry 1996 271 44 27456 27461 (Pubitemid 26367305)
12. Feinmesser R. L., Wicks S. J., Taverner C. J., Chantry A., Ca2+/calmodulin-dependent kinase II phosphorylates the epidermal growth factor receptor on multiple sites in the cytoplasmic tail and serine 744 within the kinase domain to regulate signal generation Journal of Biological Chemistry 1999 274 23 16168 16173
13. Maudsley S., Chadwick W., Wang L., Zhou Y., Martin B., Park S.-S., Bioinformatic approaches to metabolic pathways analysis Methods in Molecular Biology 2011 756 99 130
14. Watts D. J., Strogatz S. H., Collective dynamics of 'small-world9 networks Nature 1998 393 6684 440 442 (Pubitemid 128728263)
15. Zhang H., Berezov A., Wang Q., Zhang G., Drebin J., Murali R., Greene M. I., ErbB receptors: from oncogenes to targeted cancer therapies Journal of Clinical Investigation 2007 117 8 2051 2058 (Pubitemid 47224766)
16. Gschwind A., Zwick E., Prenzel N., Leserer M., Ullrich A., Cell communication networks: epidermal growth factor receptor transactivation as the paradigm for interreceptor signal transmission Oncogene 2001 20 13 1594 1600 (Pubitemid 32336847)
17. Wu W., Samet J. M., Silbajoris R., Dailey L. A., Sheppard D., Bromberg P. A., Graves L. M., Heparin-binding epidermal growth factor cleavage mediates zinc-induced epidermal growth factor receptor phosphorylation American Journal of Respiratory Cell and Molecular Biology 2004 30 4 540 547 (Pubitemid 38457186)
18. Huang R. P., Wu J. X., Fan Y., Adamson E. D., UV activates growth factor receptors via reactive oxygen intermediates Journal of Cell Biology 1996 133 1 211 220 (Pubitemid 26107108)
19. Coffer P. J., Burgering B. M., Peppelenbosch M. P., Bos J. L., Kruijer W., UV activation of receptor tyrosine kinase activity Oncogene 1995 11 3 561 569
20. Miller C. C., Hale P., Pentland A. P., Ultraviolet B injury increases prostaglandin synthesis through a tyrosine kinase-dependent pathway. Evidence for UVB-induced epidermal growth factor receptor activation Journal of Biological Chemistry 1994 269 5 3529 3533
21. Canguilhem B., Pradines A., Baudouin C., Boby C., Lajoie-Mazenc I., Charveron M., Favre G., RhoB protects human keratinocytes from UVB-induced apoptosis through epidermal growth factor receptor signaling Journal of Biological Chemistry 2005 280 52 43257 43263 (Pubitemid 43049292)
22. Pastore S., Mascia F., Mariani V., Girolomoni G., The epidermal growth factor receptor system in skin repair and inflammation Journal of Investigative Dermatology 2008 128 6 1365 1374 (Pubitemid 351693180)
23. El-Abaseri T. B., Putta S., Hansen L. A., Ultraviolet irradiation induces keratinocyte proliferation and epidermal hyperplasia through the activation of the epidermal growth factor receptor Carcinogenesis 2006 27 2 225 231 (Pubitemid 43159873)
24. Voisin L., Foisy S., Giasson E., Lambert C., Moreau P., Meloche S., EGF receptor transactivation is obligatory for protein synthesis stimulation by G protein-coupled receptors American Journal of Physiology 2002 283 2 C446 C455
25. Daub H., Wallasch C., Lankenau A., Herrlich A., Ullrich A., Signal characteristics of G protein-transactivated EGF receptor EMBO Journal 1997 16 23 7032 7044 (Pubitemid 27520803)
26. Daub H., Weiss F. U., Wallasch C., Ullrich A., Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors Nature 1996 379 6565 557 560 (Pubitemid 26049585)
27. Maudsley S., Zamah A. M., Rahman N., Blitzer J. T., Luttrell L. M., Lefkowitz R. J., Hall R. A., Platelet-derived growth factor receptor association with Na+/H+ exchanger regulatory factor potentiates receptor activity Molecular and Cellular Biology 2000 20 22 8352 8363
28. Chadwick W., Keselman A., Park S. S., Repetitive peroxide exposure reveals pleiotropic mitogen-activated protein kinase signaling mechanisms Journal of Signal Transduction 2011 2011 16
29. Sales K. J., Maudsley S., Jabbour H. N., Elevated prostaglandin EP2 receptor in endometrial adenocarcinoma cells promotes vascular endothelial growth factor expression via cyclic 3′, 5′ -adenosine monophosphate-mediated transactivation of the epidermal growth factor receptor and extracelluar signal-regulated kinase 1/2 signaling pathways Molecular Endocrinology 2004 18 6 1533 1545 (Pubitemid 38692189)
30. Prenzel N., Zwick E., Daub H., Leserer M., Abraham R., Wallasch C., Ullrich A., EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF Nature 1999 402 6764 884 888
31. Kuemmerle J. F., Murthy K. S., Coupling of the insulin-like growth factor-I receptor tyrosine kinase to Gi2 in human intestinal smooth muscle. G -dependent mitogen-activated protein kinase activation and growth Journal of Biological Chemistry 2001 276 10 7187 7194
32. Roudabush F. L., Pierce K. L., Maudsley S., Khan K. D., Luttrell L. M., Transactivation of the EGF receptor mediates IGF-1-stimulated Shc phosphorylation and ERK1/2 activation in COS-7 cells Journal of Biological Chemistry 2000 275 29 22583 22589 (Pubitemid 30621851)
33. Li Q., Hosaka T., Shikama Y., Heparin-binding EGF-like growth factor (HB-EGF) mediates 5-HT-induced insulin resistance through activation of EGF receptor-ERK1/2-mTOR pathway Endocrinology 2012 153 56 68
34. Dong X., Park S., Lin X., Copps K., Yi X., White M. F., Irs1 and Irs2 signaling is essential for hepatic glucose homeostasis and systemic growth Journal of Clinical Investigation 2006 116 1 101 114 (Pubitemid 43121795)
35. Yasumoto K., Yamada T., Kawashima A., Wang W., Li Q., Donev I. S., Tacheuchi S., Mouri H., Yamashita K., Ohtsubo K., Yano S., The EGFR ligands amphiregulin and heparin-binding EGF-like growth factor promote peritoneal carcinomatosis in CXCR4-expressing gastric cancer Clinical Cancer Research 2011 17 11 3619 3630
36. Ferrari C., Barbieri C., Caldara R., Improved oral glucose tolerance following antiserotonin treatment in patients with chemical diabetes European Journal of Clinical Pharmacology 1979 15 6 395 399 (Pubitemid 9235907)
37. Antuna-Puente B., Feve B., Fellahi S., Bastard J. P., Adipokines: the missing link between insulin resistance and obesity Diabetes and Metabolism 2008 34 1 2 11
38. Emanuelli B., Peraldi P., Filloux C., Sawka-Verhelle D., Hilton D., Van Obberghen E., SOCS-3 is an insulin-induced negative regulator of insulin signaling Journal of Biological Chemistry 2000 275 21 15985 15991 (Pubitemid 30366903)
39. Robertson R., Zhou H., Zhang T., Harmon J. S., Chronic oxidative stress as a mechanism for glucose toxicity of the beta cell in type 2 diabetes Cell Biochemistry and Biophysics 2007 48 2-3 139 146 (Pubitemid 47340880)
40. Hotamisligil G. S., Inflammation and endoplasmic reticulum stress in obesity and diabetes International Journal of Obesity 2008 32 7 S52 S54
41. Huang Y., Kim S. O., Jiang J., Frank S. J., Growth hormone-induced phosphorylation of epidermal growth factor (EGF) receptor in 3T3-F442A cells: modulation of EGF-induced trafficking and signaling Journal of Biological Chemistry 2003 278 21 18902 18913 (Pubitemid 36799273)
42. Carty M., Bowie A. G., Evaluating the role of Toll-like receptors in diseases of the central nervous system Biochemical Pharmacology 2011 81 7 825 837
43. Koff J. L., Shao M. X. G., Ueki I. F., Nadel J. A., Multiple TLRs activate EGFR via a signaling cascade to produce innate immune responses in airway epithelium American Journal of Physiology 2008 294 6 L1068 L1075
44. Siddiqui S., Martin J. G., Structural aspects of airway remodeling in asthma Current Allergy and Asthma Reports 2008 8 6 540 547
45. Koff J. L., Shao M. X. G., Kim S., Ueki I. F., Nadel J. A., Pseudomonas lipopolysaccharide accelerates wound repair via activation of a novel epithelial cell signaling cascade Journal of Immunology 2006 177 12 8693 8700 (Pubitemid 44893834)
46. Chokki M., Mitsuhashi H., Kamimura T., Metalloprotease-dependent amphiregulin release mediates tumor necrosis factor- -induced IL-8 secretion in the human airway epithelial cell line NCI-H292 Life Sciences 2006 78 26 3051 3057
47. Yamada M., Ikeuchi T., Hatanaka H., The neurotrophic action and signalling of epidermal growth factor Progress in Neurobiology 1997 51 1 19 37 (Pubitemid 27080813)
48. Fallon J. H., Seroogy K. B., Loughlin S. E., Epidermal growth factor immunoreactive material in the central nervous systemml: location and development Science 1984 224 4653 1107 1109 (Pubitemid 14106386)
49. Werner M. H., Nanney L. B., Stoscheck C. M., King L. E., Localization of immunoreactive epidermal growth factor receptors in human nervous system Journal of Histochemistry and Cytochemistry 1988 36 1 81 86 (Pubitemid 18023407)
50. Namba H., Zheng Y., Abe Y., Nawa H., Epidermal growth factor administered in the periphery influences excitatory synaptic inputs onto midbrain dopaminergic neurons in postnatal mice Neuroscience 2009 158 4 1731 1741
51. Birecree E., King L. E. Jr., Nanney L. B., Epidermal growth factor and its receptor in the developing human nervous system Developmental Brain Research 1991 60 2 145 154
52. Kornblum H. I., Hussain R. J., Bronstein J. M., Gall C. M., Lee D. C., Seroogy K. B., Prenatal ontogeny of the epidermal growth factor receptor and its ligand, transforming growth factor alpha, in the rat brain The Journal of Comparative Neurology 1997 380 243 261 (Pubitemid 27137465)
53. Fu L., Abu-Khalil A., Morrison R. S., Geschwind D. H., Kornblum H. I., Expression patterns of epidermal growth factor receptor and fibroblast growth factor receptor 1 mRNA in fetal human brain Journal of Comparative Neurology 2003 462 2 265 273 (Pubitemid 36723673)
54. Caric D., Raphael H., Viti J., Feathers A., Wancio D., Lillien L., EGFRs mediate chemotactic migration in the developing telencephalon Development 2001 128 21 4203 4216 (Pubitemid 33077032)
55. Oyagi A., Moriguchi S., Nitta A., Murata K., Oida Y., Tsuruma K., Shimazawa M., Fukunaga K., Hara H., Heparin-binding EGF-like growth factor is required for synaptic plasticity and memory formation Brain Research 2011 1419 97 104
56. Sun D., Bullock M. R., Altememi N., Zhou Z., Hagood S., Rolfe A., McGinn M. J., Hamm R., Colello R. J., The effect of epidermal growth factor in the injured brain after trauma in rats Journal of Neurotrauma 2010 27 5 923 938
57. Chillakuri C. R., Sheppard D., Lea S. M., Handford P. A., Notch receptor-ligand binding and activation: insights from molecular studies Seminars in Cell Developmental Biology 2012 23 4 421 428
58. Aguirre A., Rubio M. E., Gallo V., Notch and EGFR pathway interaction regulates neural stem cell number and self-renewal Nature 2010 467 7313 323 327
59. Zhang Y. W., Wang R., Liu Q., Zhang H., Liao F. F., Xu H., Presenilin/ -secretase-dependent processing of -amyloid precursor protein regulates EGF receptor expression Proceedings of the National Academy of Sciences of the United States of America 2007 104 25 10613 10618 (Pubitemid 47185713)
60. Li T., Wen H., Brayton C., Das P., Smithson L. A., Fauq A., Fan X., Crain B. J., Price D. L., Golde T. E., Eberhart C. G., Wong P. C., Epidermal growth factor receptor and notch pathways participate in the tumor suppressor function of -secretase Journal of Biological Chemistry 2007 282 44 32264 32273 (Pubitemid 350106457)
61. Chadwick W., Mitchell N., Caroll J., Zhou Y., Park S. S., Wang L., Becker K. G., Zhang Y., Lehrmann E., Wood W. H., Martin B., Maudsley S., Amitriptyline-mediated cognitive enhancement in aged 3Tg Alzheimer's disease mice is associated with neurogenesis and neurotrophic activity PLoS ONE 2011 6 6
62. Mishima K., Higashiyama S., Nagashima Y., Miyagi Y., Tamura A., Kawahara N., Taniguchi N., Asai A., Kuchino Y., Kirino T., Regional distribution of heparin-binding epidermal growth factor-like growth factor mRNA and protein in adult rat forebrain Neuroscience Letters 1996 213 3 153 156 (Pubitemid 26264367)
63. Stranahan A. M., Lee K., Becker K. G., Zhang Y., Maudsley S., Martin B., Cutler R. G., Mattson M. P., Hippocampal gene expression patterns underlying the enhancement of memory by running in aged mice Neurobiology of Aging 2010 31 11 1937 1949
64. Stranahan A. M., Zhou Y., Martin B., Maudsley S., Pharmacomimetics of exercise: novel approaches for hippocampally-targeted neuroprotective agents Current Medicinal Chemistry 2009 16 35 4668 4678
65. Stranahan A. M., Zhou Y., Martin B., Maudsley S., Pharmacomimetics of exercise: novel approaches for hippocampally-targeted neuroprotective agents Current Medicinal Chemistry 2009 16 35 4668 4678
66. Martin B., Pearson M., Brenneman R., Golden E., Wood W., Prabhu V., Becker K. G., Mattson M. P., Maudsley S., Gonadal transcriptome alterations in response to dietary energy intake: sensing the reproductive environment PLoS ONE 2009 4 1
67. Martin B., Pearson M., Brenneman R., Golden E., Keselman A., Iyun T., Carlson O. D., Egan J. M., Becker K. G., Wood W., Prabhu V., de Cabo R., Maudsley S., Mattson M. P., Conserved and differential effects of dietary energy intake on the hippocampal transcriptomes of females and males PLoS ONE 2008 3 6
68. Wang L., Chadwick W., Park S. S., Zhou Y., Silver N., Martin B., Maudsley S., Gonadotropin-releasing hormone receptor systemml: modulatory role in aging and neurodegeneration CNS and Neurological Disorders 2010 9 5 651 660
69. Martin B., Pearson M., Kebejian L., Golden E., Keselman A., Bender M., Carlson O., Egan J., Ladenheim B., Cadet J. L., Becker K. G., Wood W., Duffy K., Vinayakumar P., Maudsley S., Mattson M. P., Sex-dependent metabolic, neuroendocrine, and cognitive responses to dietary energy restriction and excess Endocrinology 2007 148 9 4318 4333 (Pubitemid 47295690)
70. Honda J., Oomizu S., Kiuchi Y., Komatsu N., Takeuchi S., Takahashi S., Identification of epidermal growth factor mRNA-expressing cells in the mouse anterior pituitary Neuroendocrinology 2000 71 3 155 162 (Pubitemid 30157689)
71. Kasselberg A. G., Orth D. N., Gray M. E., Stahlman M. T., Immunocytochemical localization of human epidermal growth factor/urogastrone in several human tissues Journal of Histochemistry and Cytochemistry 1985 33 4 315 322 (Pubitemid 15122789)
72. Mueller S. G., Kobrin M. S., Paterson A. J., Kudlow J. E., Transforming growth factor- expression in the anterior pituitary gland: regulation by epidermal growth factor and phorbol ester in dispersed cells Molecular Endocrinology 1989 3 6 976 983 (Pubitemid 19168588)
73. Mouihate A., Lestage J., Epidermal growth factor: a potential paracrine and autocrine system within the pituitary NeuroReport 1995 6 10 1401 1404
74. Mouihate A., Lestage J., Estrogen increases the release of epidermal growth factor from individual pituitary cells in female rats Journal of Endocrinology 1995 146 3 495 500
75. Kontogeorgos G., Stefaneanu L., Kovacs K., Cheng Z., Localization of Epidermal Growth Factor (EGF) and Epidermal Growth Factor Receptor (EGFr) in human pituitary adenomas and nontumorous pituitaries: an immunocytochemical study Endocrine Pathology 1996 7 1 63 70 (Pubitemid 126717328)
76. Armstrong J., Childs G. V., Changes in expression of epidermal growth factor receptors by anterior pituitary cells during the estrous cycle: cyclic expression by gonadotropes Endocrinology 1997 138 5 1903 1908 (Pubitemid 27180805)
77. Cooper O., Vlotides G., Fukuoka H., Greene M. I., Melmed S., Expression and function of ErbB receptors and ligands in the pituitary Endocrine-Related Cancer 2011 18 6 R197 R211
78. Oomizu S., Honda J., Takeuchi S., Kakeya T., Masui T., Takahashi S., Transforming growth factor- stimulates proliferation of mammotrophs and corticotrophs in the mouse pituitary Journal of Endocrinology 2000 165 2 493 501 (Pubitemid 30341098)
79. Borgundvaag B., Kudlow J. E., Mueller S. G., George S. R., Dopamine receptor activation inhibits estrogen-stimulated transforming growth factor- gene expression and growth in anterior pituitary, but not in uterus Endocrinology 1992 130 6 3453 3458
80. Murdoch G. H., Potter E., Nicolaisen A. K., Epidermal growth factor rapidly stimulates prolactin gene transcription Nature 1982 300 5888 192 194 (Pubitemid 12006353)
81. Miettinen P. J., Epidermal growth factor receptor in mice and menany applications to clinical practice? Annals of Medicine 1997 29 6 531 534 (Pubitemid 28135105)
82. Sibilia M., Steinbach J. P., Stingl L., Aguzzi A., Wagner E. F., A strain-independent postnatal neurodegeneration in mice lacking the EGF receptor EMBO Journal 1998 17 3 719 731 (Pubitemid 28062051)
83. Miettinen P. J., Berger J. E., Meneses J., Phung Y., Pedersen R. A., Werb Z., Derynck R., Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor Nature 1995 376 6538 337 341
84. Threadgill D. W., Dlugosz A. A., Hansen L. A., Tennenbaum T., Lichti U., Yee D., LaMantia C., Mourton T., Herrup K., Harris R. C., Barnard J. A., Yuspa S. H., Coffey R. J., Magnuson T., Targeted disruption of mouse EGF receptor: effect of genetic background on mutant phenotype Science 1995 269 5221 230 234
85. Sibilia M., Wagner E. F., Strain-dependent epithelial defects in mice lacking the EGF receptor Science 1995 269 5221 234 238
86. Kornblum H. I., Hussain R., Wiesen J., Miettinen P., Zurcher S. D., Chow K., Derynck R., Werb Z., Abnormal astrocyte development and neuronal death in mice lacking the epidermal growth factor receptor Journal of Neuroscience Research 1998 53 6 697 717 (Pubitemid 28423878)
87. Anchan R. M., Reh T. A., Angello J., Balliet A., Walker M., EGF and TGF- stimulate retinal neuroepithelial cell proliferation in vitro Neuron 1991 6 6 923 936
88. Morrison R. S., Kornblum H. I., Leslie F. M., Bradshaw R. A., Trophic stimulation of cultured neurons from neonatal rat brain by epidermal growth factor Science 1987 238 4823 72 75 (Pubitemid 17150484)
89. Morrison R. S., Keating R. F., Moskal J. R., Basic fibroblast growth factor and epidermal growth factor exert differential trophic effects on CNS neurons Journal of Neuroscience Research 1988 21 1 71 79 (Pubitemid 19020954)
90. Alexi T., Hefti F., Trophic actions of transforming growth factor on mesencephalic dopaminergic neurons developing in culture Neuroscience 1993 55 4 903 918 (Pubitemid 23231903)
91. Leutz A., Schachner M., Epidermal growth factor stimulates DNA-synthesis of astrocytes in primary cerebellar cultures Cell and Tissue Research 1981 220 2 393 404 (Pubitemid 12206424)
92. Simpson D. L., Morrison R., De Vellis J., Herschman H. R., Epidermal growth factor binding and mitogenic activity on purified populations of cells from the central nervous system Journal of Neuroscience Research 1982 8 2-3 453 462 (Pubitemid 13169646)
93. Birecree E., Whetsell W. O., Stoscheck Ch., King L. E., Nanney L. B., Immunoreactive epidermal growth factor receptors in neuritic plaques from patients with Alzheimer's disease Journal of Neuropathology and Experimental Neurology 1988 47 5 549 560
94. Styren S. D., Mufson E. J., Styren G. C., Civin W. H., Rogers J., Epidermal growth factor receptor expression in demented and aged human brain Brain Research 1990 512 2 347 352 (Pubitemid 20107480)
95. Styren S. D., DeKosky S. T., Rogers J., Mufson E. J., Epidermal growth factor receptor expression in demented elderly: localization to vascular endothelial cells of brain, pituitary and skin Brain Research 1993 615 2 181 190 (Pubitemid 23189637)
96. Chadwick W., Boyle J. P., Zhou Y., Wang L., Park S. S., Martin B., Wang R., Becker K. G., Wood W. H., Zhang Y., Peers C., Maudsley S., Multiple Oxygen tension environments reveal diverse patterns of transcriptional regulation in primary astrocytes PLoS ONE 2011 6 6
97. Junier M. P., Ying Jun Ma, Costa M. E., Hoffman G., Hill D. F., Ojeda S. R., Transforming growth factor contributes to the mechanism by which hypothalamic injury induces precocious puberty Proceedings of the National Academy of Sciences of the United States of America 1991 88 21 9743 9747 (Pubitemid 21915709)
98. Zhu G., Mehler M. F., Mabie P. C., Kessler J. A., Developmental changes in neural progenitor cell lineage commitment do not depend on epidermal growth factor receptor signaling Journal of Neuroscience Research 2000 59 3 312 320 (Pubitemid 30107970)
99. Burrows R. C., Wancio D., Levitt P., Lillien L., Response diversity and the timing of progenitor cell maturation are regulated by developmental changes in EGFR expression in the cortex Neuron 1997 19 2 251 267 (Pubitemid 27374226)
100. Viti J., Feathers A., Phillips J., Lillien L., Epidermal growth factor receptors control competence to interpret leukemia inhibitory factor as an astrocyte inducer in developing cortex Journal of Neuroscience 2003 23 8 3385 3393 (Pubitemid 36531980)
101. Wagner B., Natarajan A., Grnaug S., Kroismayr R., Wagner E. F., Sibilia M., Neuronal survival depends on EGFR signaling in cortical but not midbrain astrocytes EMBO Journal 2006 25 4 752 762 (Pubitemid 43292437)
102. Ojeda S. R., Urbanski H. F., Costa M. E., Hill D. F., Moholt-Siebert M., Involvement of transforming growth factor in the release of luteinizing hormone-releasing hormone from the developing female hypothalamus Proceedings of the National Academy of Sciences of the United States of America 1990 87 24 9698 9702 (Pubitemid 120016510)
103. Ma Y. J., Hill D. F., Junier M. P., Costa M. E., Felder S. E., Ojeda S. R., Expression of epidermal growth factor receptor changes in the hypothalamus during the onset of female puberty Molecular and Cellular Neurosciences 1994 5 3 246 262 (Pubitemid 24172507)
104. Li B., Yang Z., Hou J., McCracken A., Jennings M. A., Ma M. Y. J., Compromised reproductive function in adult female mice selectively expressing mutant ErbB-1 tyrosine kinase receptors in astroglia Molecular Endocrinology 2003 17 11 2365 2376 (Pubitemid 37352545)
105. Vadigepalli R., Hao H., Miller G. M., Liu H., Schwaber J. S., Epidermal growth factor receptor-induced circadian-time-dependent gene regulation in suprachiasmatic nucleus NeuroReport 2006 17 13 1437 1441 (Pubitemid 44299390)
106. Zak D. E., Hao H., Vadigepalli R., Miller G. M., Ogunnaike B. A., Schwaber J. S., Systems analysis of circadian time-dependent neuronal epidermal growth factor receptor signaling Genome Biology 2006 7 6, article R48
107. Kramer A., Yang F. C., Snodgrass P., Li X., Scammell T. E., Davis F. C., Weitz C. J., Regulation of daily locomotor activity and sleep by hypothalamic EGF receptor signating Science 2001 294 5551 2511 2515 (Pubitemid 34027284)
108. Snodgrass-Belt P., Gilbert J. L., Davis F. C., Central administration of transforming growth factor-alpha and neuregulin-1 suppress active behaviors and cause weight loss in hamsters Brain Research 2005 1038 2 171 182 (Pubitemid 40332682)
109. Cai H., Cong W., Ji S., Rothman S., Maudsley S., Martin B., Metabolic dysfunction in Alzheimer's disease and related neurodegenerative disorders Current Alzheimer Research 2012 9 1 5 17
110. Martin B., Brenneman R., Becker K. G., Gucek M., Cole R. N., Maudsley S., iTRAQ analysis of complex proteome alterations in 3xTgAD Alzheimer's mice: understanding the interface between physiology and disease PLoS ONE 2008 3 7
111. Martin B., Golden E., Keselman A., Stone M., Mattson M. P., Egan J. M., Maudsley S., Therapeutic perspectives for the treatment of Huntington's disease: treating the whole body Histology and Histopathology 2008 23 2 237 250
112. Maudsley S., Mattson M. P., Protein twists and turns in Alzheimer disease Nature Medicine 2006 12 4 392 393
113. Maudsley S., Martin B., Luttrell L. M., G protein-coupled receptor signaling complexity in neuronal tissue: implications for novel therapeutics Current Alzheimer Research 2007 4 1 3 19 (Pubitemid 46293880)
114. Maudsley S., Chadwick W., Brenneman R., Martin B., Complex and multidimensional lipid raft alterations in a murine model of Alzheimer's disease International Journal of Alzheimer's Disease 2010 2010 56
115. Hiramatsu M., Kashimata M., Murayama M., Minami N., Sato A., Influence of age on epidermal growth factor receptor level in the rat brain Experientia 1988 44 1 23 25 (Pubitemid 18058085)
116. Ferrer I., Alcntara S., Ballabriga J., Olivé M., Blanco R., Rivera R., Carmona M., Berruezo M., Pitarch S., Planas A. M., Transforming growth factor- (TGF- ) and epidermal growth factor-receptor (EGF-R) immunoreactivity in normal and pathologic brain Progress in Neurobiology 1996 49 2 99 123 (Pubitemid 26253264)
117. Chadwick W., Zhou Y., Park S. S., Wang L., Mitchell N., Stone M. D., Becker K. G., Martin B., Maudsley S., Minimal peroxide exposure of neuronal cells induces multifaceted adaptive responses PLoS ONE 2010 5 12
118. Price K. A., Filiz G., Caragounis A., Du T., Laughton K. M., Masters C. L., Sharples R. A., Hill A. F., Li Q. X., Donnelly P. S., Barnham K. J., Crouch P. J., White A. R., Activation of epidermal growth factor receptor by metal-ligand complexes decreases levels of extracellular amyloid beta peptide International Journal of Biochemistry and Cell Biology 2008 40 9 1901 1917
119. Jiang D., Li X., Williams R., Patel S., Men L., Wang Y., Zhou F., Ternary complexes of iron, amyloid-, and nitrilotriacetic acid: binding affinities, redox properties, and relevance to iron-induced oxidative stress in Alzheimer's disease Biochemistry 2009 48 33 7939 7947
120. Barnham K. J., Masters C. L., Bush A. I., Neurodegenerative diseases and oxidatives stress Nature Reviews Drug Discovery 2004 3 3 205 214 (Pubitemid 38379987)
121. Villares J., Faucheux B., Herrero M. T., Obeso J. A., Duyckaerts C., Hauw J. J., Agid Y., Hirsch E. C., [125I]EGF binding in basal ganglia of patients with Parkinson's disease and progressive supranuclear palsy and in MPTP-treated monkeys Experimental Neurology 1998 154 1 146 156 (Pubitemid 28553575)
122. O'Keeffe G. C., Tyers P., Aarsland D., Dalley J. W., Barker R. A., Caldwellf M. A., Dopamine-induced proliferation of adult neural precursor cells in the mammalian subventricular zone is mediated through EGF Proceedings of the National Academy of Sciences of the United States of America 2009 106 21 8754 8759
123. Yoon S., Choi M. H., Chang M. S., Baik J. H., Wnt5a-dopamine D2 receptor interactions regulate dopamine neuron development via extracellular signal-regulated kinase (ERK) activation Journal of Biological Chemistry 2011 286 18 15641 15651
124. Carlson O., Martin B., Stote K. S., Golden E., Maudsley S., Najjar S. S., Ferrucci L., Ingram D. K., Longo D. L., Rumpler W. V., Baer D. J., Egan J., Mattson M. P., Impact of reduced meal frequency without caloric restriction on glucose regulation in healthy, normal-weight middle-aged men and women Metabolism 2007 56 12 1729 1734 (Pubitemid 350060941)
125. Park S. S., Stranahan A. M., Chadwick W., Zhou Y., Wang L., Martin B., Becker K. G., Maudsley S., Cortical gene transcription response patterns to water maze training in aged mice BMC Neuroscience 2011 12, article 63
126. Harvie M. N., Pegington M., Mattson M. P., Frystyk J., Dillon B., Evans G., Cuzick J., Jebb S. A., Martin B., Cutler R. G., Son T. G., Maudsley S., Carlson O. D., Egan J. M., Flyvbjerg A., Howell A., The effects of intermittent or continuous energy restriction on weight loss and metabolic disease risk markers: a randomized trial in young overweight women International Journal of Obesity 2011 35 5 714 727
127. Golden E., Emiliano A., Maudsley S., Windham B. G., Carlson O. D., Egan J. M., Driscoll I., Ferrucci L., Martin B., Mattson M. P., Circulating brain-derived neurotrophic factor and indices of metabolic and cardiovascular health: data from the baltimore longitudinal study of aging PLoS ONE 2010 5 4
128. Martin B., Golden E., Egan J. M., Mattson M. P., Maudsley S., Reduced energy intake: the secret to a long and healthy life? IBS Journal of Science 2007 2 35 39
129. Johnson J. B., Summer W., Cutler R. G., Martin B., Hyun D. H., Dixit V. D., Pearson M., Nassar M., Telljohann R., Maudsley S., Carlson O., John S., Laub D. R., Mattson M. P., Alternate day calorie restriction improves clinical findings and reduces markers of oxidative stress and inflammation in overweight adults with moderate asthma Free Radical Biology and Medicine 2007 42 665 674 (Pubitemid 46205148)
130. Martin B., Mattson M. P., Maudsley S., Caloric restriction and intermittent fasting: two potential diets for successful brain aging Ageing Research Reviews 2006 5 3 332 353 (Pubitemid 44374430)
131. Derynck R., Goeddel D. V., Ullrich A., Synthesis of messenger RNAs for transforming growth factors and and the epidermal growth factor receptor by human tumors Cancer Research 1987 47 3 707 712 (Pubitemid 17027960)
132. Wong A. J., Ruppert J. M., Bigner S. H., Grzeschik C. H., Humphrey P. A., Bigner D. S., Vogelstein B., Structural alterations of the epidermal growth factor receptor gene in human gliomas Proceedings of the National Academy of Sciences of the United States of America 1992 89 7 2965 2969
133. Menzo S., Clementi M., Alfani E., Bagnarelli P., Iacovacci S., Manzin A., Dandri M., Natoli G., Levrero M., Carloni G., Trans-activation of epidermal growth factor receptor gene by the hepatitis B virus X-gene product Virology 1993 196 2 878 882
134. Yarden Y., Sliwkowski M. X., Untangling the ErbB signalling network Nature Reviews Molecular Cell Biology 2001 2 2 127 137 (Pubitemid 33674041)
135. Sadaf Farooqi I., O'Rahilly S., Leptin: a pivotal regulator of human energy homeostasis American Journal of Clinical Nutrition 2009 89 3 980S 984S
136. Amishima M., Munakata M., Nasuhara Y., Sato A., Takahashi T., Homma Y., Kawakami Y., Expression of epidermal growth factor and epidermal growth factor receptor immunoreactivity in the asthmatic human airway American Journal of Respiratory and Critical Care Medicine 1998 157 6 1907 1912
137. Kimura M., Inoue H., Hirabayashi K., Natsume H., Ogihara M., Glycyrrhizin and some analogues induce growth of primary cultured adult rat hepatocytes via epidermal growth factor receptors European Journal of Pharmacology 2001 431 2 151 161 (Pubitemid 33132121)
138. Kashimata M., Hiramatsu M., Minami N., Sex difference and regulatory mechanism of epidermal growth factor receptor in the rat liver Folia Pharmacologica Japonica 1990 96 4 169 183 (Pubitemid 20343814)
139. Natarajan A., Wagner B., Sibilia M., The EGF receptor is required for efficient liver regeneration Proceedings of the National Academy of Sciences of the United States of America 2007 104 43 17081 17086 (Pubitemid 350210995)
140. Mukku V. R., Regulation of epidermal growth factor receptor levels by thyroid hormone Journal of Biological Chemistry 1984 259 10 6543 6547 (Pubitemid 14108206)
141. Kashimata M., Hiramatsu M., Minami N., Sex difference in epidermal growth factor receptor levels in rat liver plasma membrane Endocrinology 1988 122 5 1707 1714
142. Freidenberg G. R., Klein H. H., Kladde M. P., Regulation of epidermal growth factor receptor number and phosphorylation by fasting in rat liver Journal of Biological Chemistry 1986 261 2 752 757 (Pubitemid 16161736)
143. Earp H. S., O'Keefe E. J., Epidermal growth factor receptor number decreases during rat liver regeneration Journal of Clinical Investigation 1981 67 5 1580 1583 (Pubitemid 11099376)
144. Okamoto M., Kahn C. R., Maron R., White M. F., Decreased autophosphorylation of EGF receptor in insulin-deficient diabetic rats American Journal of Physiology 1988 254 4 17/4
145. Lev-Ran A., Hwang D. L., Barseghian G., Decreased expression of liver epidermal growth factor receptors in rats with alloxan and streptozotocin diabetes Biochemical and Biophysical Research Communications 1986 137 1 258 262 (Pubitemid 16056060)
146. Kashimata M., Hiramatsu M., Minami N., Effect of streptozotocin-induced diabetes on epidermal growth factor receptors in rat liver plasma membrane Biochimica et Biophysica Acta 1987 923 3 496 500 (Pubitemid 17047593)
147. Kasayama S., Yoshimura M., Oka T., Decreased expression of hepatic epidermal growth factor receptor gene in diabetic mice Journal of Molecular Endocrinology 1989 3 1 49 56 (Pubitemid 19177444)
148. Natsumi Y., Kashimata M., Hiramatsu M., Effect of experimental diabetes on epidermal growth factor (EGF) receptors in the rat liver Meikai Daigaku Shigaku Zasshi 1989 18 1 21 36
149. Musallam L., thier C., Haddad P. S., Bilodeau M., Role of EGF receptor tyrosine kinase activity in antiapoptotic effect of EGF on mouse hepatocytes American Journal of Physiology 2001 280 6 G1360 G1369
150. Lee M. Y., Park S. H., Lee Y. J., Heo J. S., Lee J. H., Han H. J., EGF-induced inhibition of glucose transport is mediated by PKC and MAPK signal pathways in primary cultured chicken hepatocytes American Journal of Physiology 2006 291 4 G744 G750
151. Yamauchi T., Ueki K., Tobe K., Tamemoto H., Sekine N., Wada M., Honjo M., Takahashi M., Takahashi T., Hirai H., Tushima T., Akanuma Y., Fujita T., Komuro I., Yazaki Y., Kadowaki T., Tyrosine phosphorylation of the EGF receptor by the kinase Jak2 is induced by growth hormone Nature 1997 390 6655 91 96 (Pubitemid 27494763)
152. Abou-Rjaily G. A., Sang J. L., May D., Al-Share Q. Y., DeAngelis A. M., Ruch R. J., Neumaier M., Kalthoff H., Lin S. H., Najjar S. M., CEACAM1 modulates epidermal growth factor receptor-mediated cell proliferation Journal of Clinical Investigation 2004 114 7 944 952 (Pubitemid 39578722)
153. DeFronzo R. A., Ferrannini E., Insulin resistance: a multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease Diabetes Care 1991 14 3 173 194
154. Harvie M., Hooper L., Howell A. H., Central obesity and breast cancer risk: a systematic review Obesity Reviews 2003 4 3 157 173 (Pubitemid 36950578)
155. Calle E. E., Rodriguez C., Walker-Thurmond K., Thun M. J., Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. Adults New England Journal of Medicine 2003 348 17 1625 1638 (Pubitemid 36459468)
156. Vacaresse N., Lajoie-Mazenc I., Augé N., Suc I., Frisach M. F., Salvayre R., Ngre-Salvayre A., Activation of epithelial growth factor receptor pathway by unsaturated fatty acids Circulation Research 1999 85 10 892 899 (Pubitemid 29534163)
157. Soto-Guzman A., Navarro-Tito N., Castro-Sanchez L., Martinez-Orozco R., Salazar E. P., Oleic acid promotes MMP-9 secretion and invasion in breast cancer cells Clinical and Experimental Metastasis 2010 27 7 505 515
158. Baldeweg S. E., Golay A., Natali A., Balkau B., Del Prato S., Coppack S. W., Insulin resistance, lipid and fatty acid concentrations in 867 healthy Europeans European Journal of Clinical Investigation 2000 30 1 45 52 (Pubitemid 30071856)
159. Hajri T., Han X. X., Bonen A., Abumrad N. A., Defective fatty acid uptake modulates insulin responsiveness and metabolic responses to diet in CD36-null mice Journal of Clinical Investigation 2002 109 10 1381 1389 (Pubitemid 34546903)
160. Higashiyama S., Abraham J. A., Miller J., Fiddes J. C., Klagsbrun M., A heparin-binding growth factor secreted by macrophage-like cells that is related to EGF Science 1991 251 4996 936 939 (Pubitemid 21926188)
161. Miettinen P. J., Heikinheimo K., Transforming growth factor-alpha (TGF- ) and insulin gene expression in human fetal pancreas Development 1992 114 4 833 840
162. Miettinen P. J., Huotari M. A., Koivisto T., Ustinov J., Palgi J., Rasilainen S., Lehtonen E., Keski-Oja J., Otonkoski T., Impaired migration and delayed differentiation of pancreatic islet cells in mice lacking EGF-receptors Development 2000 127 12 2617 2627 (Pubitemid 30426809)
163. Hakonen E., Ustinov J., Mathijs I., Palgi J., Bouwens L., Miettinen P. J., Otonkoski T., Epidermal growth factor (EGF)-receptor signalling is needed for murine beta cell mass expansion in response to high-fat diet and pregnancy but not after pancreatic duct ligation Diabetologia 2011 54 7 1735 1743
164. Huotari M. A., Miettinen P. J., Palgi J., Koivisto T., Ustinov J., Harari D., Yarden Y., Otonkoski T., ErbB signaling regulates lineage determination of developing pancreatic islet cells in embryonic organ culture Endocrinology 2002 143 11 4437 4446 (Pubitemid 35239578)
165. Vinter-Jensen L., Juhl C. O., Teglbjaerg P. S., Poulsen S. S., Dajani E. Z., Nexo E., Systemic treatment with epidermal growth factor in pigs induces ductal proliferations in the pancreas Gastroenterology 1997 113 4 1367 1374 (Pubitemid 27418991)
166. Cras-Méneur C., Elghazi L., Czernichow P., Scharfmann R., Epidermal growth factor increases undifferentiated pancreatic embryonic cells in vitro: a balance between proliferation and differentiation Diabetes 2001 50 7 1571 1579 (Pubitemid 33639597)
167. Means A. L., Ray K. C., Singh A. B., Washington M. K., Whitehead R. H., Harris R. C., Wright C. V. E., Coffey R. J., Leach S. D., Overexpression of Heparin-binding EGF-like growth factor in mouse pancreas results in fibrosis and epithelial metaplasia Gastroenterology 2003 124 4 1020 1036 (Pubitemid 36389805)
168. Buteau J., Foisy S., Joly E., Prentki M., Glucagon-like peptide 1 induces pancreatic -cell proliferation via transactivation of the epidermal growth factor receptor Diabetes 2003 52 1 124 132 (Pubitemid 36042116)
169. Drucker D. J., Glucagon-like peptides Diabetes 1998 47 2 159 169 (Pubitemid 28079969)
170. Widmann C., Burki E., Dolci W., Thorens B., Signal transduction by the cloned glucagon-like peptide-1 receptor: comparison with signaling by the endogenous receptors of cell lines Molecular Pharmacology 1994 45 5 1029 1035 (Pubitemid 24155796)
171. Chapter M. C., White C. M., DeRidder A., Chadwick W., Martin B., Maudsley S., Chemical modification of Class II G protein-coupled receptor ligands: frontiers in the development of peptide analogs as neuroendocrine pharmacological therapies Pharmacology and Therapeutics 2010 125 1 39 54
172. Buteau J., Foisy S., Joly E., Prentki M., Glucagon-like peptide 1 induces pancreatic -cell proliferation via transactivation of the epidermal growth factor receptor Diabetes 2003 51 A375 A376
173. Chadwick W., Zhou Y., Park S. S., Wang L., Mitchell N., Stone M. D., Becker K. G., Martin B., Maudsley S., Minimal peroxide exposure of neuronal cells induces multifaceted adaptive responses PloS ONE 2010 5 12
174. Roztocil E., Nicholl S. M., Davies M. G., Insulin-induced epidermal growth factor activation in vascular smooth muscle cells is ADAM-dependent Surgery 2008 144 2 245 251
175. Leof E. B., Wharton W., Van Wyk J. J., Pledger W. J., Epidermal growth factor (EGF) and somatomedin C regulate G1 progression in competent BALB/c-3T3 cells Experimental Cell Research 1982 141 1 107 115 (Pubitemid 13219187)
176. Saad S., Stevens V. A., Wassef L., Poronnik P., Kelly D. J., Gilbert R. E., Pollock C. A., High glucose transactivates the EGF receptor and up-regulates serum glucocorticoid kinase in the proximal tubule Kidney International 2005 68 3 985 997 (Pubitemid 43246415)
177. Cohen S., Carpenter G., Human epidermal growth factor: isolation and chemical and biological properties Proceedings of the National Academy of Sciences of the United States of America 1975 72 4 1317 1321
178. Barnham K. J., Amadoruge P. C., Alzheimer's disease and metals: a review of the involvement of cellular membrane receptors in metallosignalling International Journal of Alzheimer's Disease 2011 2011 9
179. Lewin G. R., Barde Y. A., Physiology of the neurotrophins Annual Review of Neuroscience 1996 19 289 317 (Pubitemid 26080831)
180. Connor B., Young D., Yan Q., Faull R. L. M., Synek B., Dragunow M., Brain-derived neurotrophic factor is reduced in Alzheimer's disease Molecular Brain Research 1997 49 1-2 71 81 (Pubitemid 27453116)
181. Phillips H. S., Hains J. M., Armanini M., Laramee G. R., Johnson S. A., Winslow J. W., BDNF mRNA is decreased in the hippocampus of individuals with Alzheimer's disease Neuron 1991 7 5 695 702
182. Murray K. D., Gall C. M., Jones E. G., Isackson P. J., Differential regulation of brain-derived neurotrophic factor and type II calcium/calmodulin- dependent protein kinase messenger RNA expression in Alzheimer's disease Neuroscience 1994 60 1 37 48 (Pubitemid 24147606)
183. Narisawa-Saito M., Wakabayashi K., Tsuji S., Takahashi H., Nawa H., Regional specificity of alterations in NGF, BDNF and NT-3 levels in Alzheimer's disease NeuroReport 1996 7 18 2925 2928 (Pubitemid 26426361)
184. Chen G., Kolbeck R., Barde Y. A., Bonhoeffer T., Kossel A., Relative contribution of endogenous neurotrophins in hippocampal long-term potentiation Journal of Neuroscience 1999 19 18 7983 7990 (Pubitemid 30225794)
185. Kossel A. H., Cambridge S. B., Wagner U., Bonhoeffer T., A caged Ab reveals an immediate/instructive effect of BDNF during hippocampal synaptic potentiation Proceedings of the National Academy of Sciences of the United States of America 2001 98 25 14702 14707 (Pubitemid 33121455)