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Volumn 127, Issue 12, 2000, Pages 2617-2627

Impaired migration and delayed differentiation of pancreatic islet cells in mice lacking EGF-receptors

Author keywords

EGF receptor; Gene targeting; Matrix metalloproteinases; Mouse; Pancreas

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; GELATINASE A; GELATINASE B; PLASMINOGEN ACTIVATOR INHIBITOR 1; TISSUE PLASMINOGEN ACTIVATOR; UROKINASE;

EID: 0033936875     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (173)

References (62)
  • 1
    • 0029950724 scopus 로고    scopus 로고
    • The morphogenesis of the pancreatic mesenchyme is uncoupled from that of the pancreatic epithelium in IPF1/PDX1-deficient mice
    • Ahlgren, U., Jonsson, J. and Edlund, H. (1996). The morphogenesis of the pancreatic mesenchyme is uncoupled from that of the pancreatic epithelium in IPF1/PDX1-deficient mice. Development 122, 1409-1416.
    • (1996) Development , vol.122 , pp. 1409-1416
    • Ahlgren, U.1    Jonsson, J.2    Edlund, H.3
  • 3
    • 0027282962 scopus 로고
    • The role of E-cadherin and integrins in mesoderm differentiation and migration at the mammalian primitive streak
    • Burdsal, C. A., Damsky, C. H. and Pedersen, R. A. (1993). The role of E-cadherin and integrins in mesoderm differentiation and migration at the mammalian primitive streak. Development 118, 829-844.
    • (1993) Development , vol.118 , pp. 829-844
    • Burdsal, C.A.1    Damsky, C.H.2    Pedersen, R.A.3
  • 4
    • 0028176477 scopus 로고
    • A Neu acquaintance for erbB3 and erhB4: A role for receptor heterodimerization in growth signalling
    • Carraway III, K. L. and Cantley, L. C. (1994). A Neu acquaintance for erbB3 and erhB4: A role for receptor heterodimerization in growth signalling. Cell 78, 5-8.
    • (1994) Cell , vol.78 , pp. 5-8
    • Carraway K.L. III1    Cantley, L.C.2
  • 5
    • 0031008068 scopus 로고    scopus 로고
    • Matrix metalloproteinases regulate morphogenesis, migration and remodeling of epithelium, tongue skeletal muscle and cartilage in the mandibular arch
    • Chin, J. R. and Werb, Z. (1997). Matrix metalloproteinases regulate morphogenesis, migration and remodeling of epithelium, tongue skeletal muscle and cartilage in the mandibular arch. Development 124, 1519-1530.
    • (1997) Development , vol.124 , pp. 1519-1530
    • Chin, J.R.1    Werb, Z.2
  • 6
    • 0028361162 scopus 로고
    • Expression of neural cell adhesion molecule (N-CAM) in rat islets and its role in islet cell type segregation
    • Cirulli, V., Baetens, D., Rutishauser, U., Halban, P., Orci, L. and Rouiller, D. (1994). Expression of neural cell adhesion molecule (N-CAM) in rat islets and its role in islet cell type segregation. J. Cell Sci. 107, 1429-1436.
    • (1994) J. Cell Sci. , vol.107 , pp. 1429-1436
    • Cirulli, V.1    Baetens, D.2    Rutishauser, U.3    Halban, P.4    Orci, L.5    Rouiller, D.6
  • 7
    • 0033081796 scopus 로고    scopus 로고
    • Plasminogen activators and matrix metalloproteases, mediators of extracellular proteolysis in inflammatory demyelination of the central nervous system
    • Cuzner, M. L. and Opdenakker, G. (1999). Plasminogen activators and matrix metalloproteases, mediators of extracellular proteolysis in inflammatory demyelination of the central nervous system. Neuroimmunol. 94, 1-14.
    • (1999) Neuroimmunol. , vol.94 , pp. 1-14
    • Cuzner, M.L.1    Opdenakker, G.2
  • 8
    • 0029793745 scopus 로고    scopus 로고
    • Cadherins regulate aggregation of pancreatic β-cells in vivo
    • Dahl, U., Sjödin, A. and Semb, H. (1996). Cadherins regulate aggregation of pancreatic β-cells in vivo. Development 122, 2895-2902.
    • (1996) Development , vol.122 , pp. 2895-2902
    • Dahl, U.1    Sjödin, A.2    Semb, H.3
  • 9
    • 0031454062 scopus 로고    scopus 로고
    • ErbB3 is required for normal cerehellar and cardiac development: A comparison with ErbB2- and heregulin-deficient mice
    • Erickson, S. L., O'Shea, K. S., Ghaboosi, N., Loverro, L., Frantz, G., Bauer, M., Lu, L. H. and Moore, M. W. (1997). ErbB3 is required for normal cerehellar and cardiac development: a comparison with ErbB2- and heregulin-deficient mice. Development 124, 4999-5011.
    • (1997) Development , vol.124 , pp. 4999-5011
    • Erickson, S.L.1    O'Shea, K.S.2    Ghaboosi, N.3    Loverro, L.4    Frantz, G.5    Bauer, M.6    Lu, L.H.7    Moore, M.W.8
  • 10
    • 0028785406 scopus 로고
    • Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor
    • Gassmann, M., Casagranda, F., Orioli, D., Simon, H., Lai, C., Klein, R. and Lemke, G. (1995). Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor. Nature 378, 390-394.
    • (1995) Nature , vol.378 , pp. 390-394
    • Gassmann, M.1    Casagranda, F.2    Orioli, D.3    Simon, H.4    Lai, C.5    Klein, R.6    Lemke, G.7
  • 11
    • 0030041280 scopus 로고    scopus 로고
    • Lineage specific morphogenesis in the developing pancreas: Role of mesenchymal factors
    • Gittes, G., Galante, P., Hanahan, D., Rutter, W. and Debas, H. (1996). Lineage specific morphogenesis in the developing pancreas: role of mesenchymal factors. Development 122, 439-447.
    • (1996) Development , vol.122 , pp. 439-447
    • Gittes, G.1    Galante, P.2    Hanahan, D.3    Rutter, W.4    Debas, H.5
  • 12
    • 0026518591 scopus 로고
    • Onset of cell-specific gene expression in the developing mouse pancreas
    • Gittes, G. K. and Rutter, W. J. (1992). Onset of cell-specific gene expression in the developing mouse pancreas. Proc. Natl. Acad. Sci. USA 89, 1128-1132.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 1128-1132
    • Gittes, G.K.1    Rutter, W.J.2
  • 14
    • 0032860478 scopus 로고    scopus 로고
    • Pancreas dorsal lobe agenesis and abnormal islets of Langerhans in H1xb9-deficient mice
    • Harrison, K. A., Thaler, J., Pfaff, S. L., Gu, H. and Kehrl, J. H. (1999). Pancreas dorsal lobe agenesis and abnormal islets of Langerhans in H1xb9-deficient mice. Nat. Genet. 23, 71-75.
    • (1999) Nat. Genet. , vol.23 , pp. 71-75
    • Harrison, K.A.1    Thaler, J.2    Pfaff, S.L.3    Gu, H.4    Kehrl, J.H.5
  • 15
    • 0032502669 scopus 로고    scopus 로고
    • The epidermal growth factor receptor modulates the interaction of E-cadherin with the actin cytoskeleton
    • Hazan, R. B. and Norton, L. (1998). The epidermal growth factor receptor modulates the interaction of E-cadherin with the actin cytoskeleton. J. Biol. Chem. 273, 9078-9084.
    • (1998) J. Biol. Chem. , vol.273 , pp. 9078-9084
    • Hazan, R.B.1    Norton, L.2
  • 16
    • 0029964159 scopus 로고    scopus 로고
    • Forced expression of E-cadherin in the mouse intestinal epithelium slows cell migration and provides evidence for nonautonomous regulation of cell fate in a self-renewing system
    • Hermiston, M. L., Wong, M. H. and Gordon, J. I. (1996). Forced expression of E-cadherin in the mouse intestinal epithelium slows cell migration and provides evidence for nonautonomous regulation of cell fate in a self-renewing system. Genes Dev. 10, 985-996.
    • (1996) Genes Dev. , vol.10 , pp. 985-996
    • Hermiston, M.L.1    Wong, M.H.2    Gordon, J.I.3
  • 17
    • 0028170977 scopus 로고
    • Beta-catenin mediates the interaction of the cadherin-catenin complex with epidermal growth factor receptor
    • Hoschuetzky, H., Aberle, H. and Kemler, R. (1994). Beta-catenin mediates the interaction of the cadherin-catenin complex with epidermal growth factor receptor. J. Cell Biol. 127, 1375-1380.
    • (1994) J. Cell Biol. , vol.127 , pp. 1375-1380
    • Hoschuetzky, H.1    Aberle, H.2    Kemler, R.3
  • 18
    • 0031763478 scopus 로고    scopus 로고
    • Growth factor-mediated proliferation and differentiation of insulin-producing INS-1 and RINm5F cells: Identification of betacellulin as a novel beta-cell mitogen
    • Huotari, M. A., Palgi, J. and Otonkoski, T. (1998). Growth factor-mediated proliferation and differentiation of insulin-producing INS-1 and RINm5F cells: identification of betacellulin as a novel beta-cell mitogen. Endocrinology 139, 1494-1499.
    • (1998) Endocrinology , vol.139 , pp. 1494-1499
    • Huotari, M.A.1    Palgi, J.2    Otonkoski, T.3
  • 19
    • 0028149890 scopus 로고
    • Insulin promoter factor 1 is required for pancreas development in mice
    • Jonsson, J., Carlsson, L., Edlund, T. and Edlund, H. (1994). Insulin promoter factor 1 is required for pancreas development in mice. Nature 371, 606-609.
    • (1994) Nature , vol.371 , pp. 606-609
    • Jonsson, J.1    Carlsson, L.2    Edlund, T.3    Edlund, H.4
  • 21
    • 0030888746 scopus 로고    scopus 로고
    • Epidermal growth factor and amphiregulin up-regulate matrix metalloproteinase-9 (MMP-9) in human breast cancer cells
    • Kondapaka, S. B., Fridman, R. and Reddy, K. B. (1997). Epidermal growth factor and amphiregulin up-regulate matrix metalloproteinase-9 (MMP-9) in human breast cancer cells. Int. J. Cancer 70, 722-726.
    • (1997) Int. J. Cancer , vol.70 , pp. 722-726
    • Kondapaka, S.B.1    Fridman, R.2    Reddy, K.B.3
  • 22
    • 0032530365 scopus 로고    scopus 로고
    • Abnormal astrocyte development and apoptosis of forebrain structures in mice lacking the epidermal growth factor receptor
    • Kornblum, H. I., Hussain, R., Wiesen, J., Miettinen, P. J., Chow, K., Derynck, R. and Werb, Z. (1998). Abnormal astrocyte development and apoptosis of forebrain structures in mice lacking the epidermal growth factor receptor. J. Neurosci. Res. 53, 697-717.
    • (1998) J. Neurosci. Res. , vol.53 , pp. 697-717
    • Kornblum, H.I.1    Hussain, R.2    Wiesen, J.3    Miettinen, P.J.4    Chow, K.5    Derynck, R.6    Werb, Z.7
  • 23
    • 0024326947 scopus 로고
    • Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: Evidence for overexpression in a subset of human mammary tumors
    • Kraus, M. H., Issing, W., Miki, T., Popescu, N. C. and Aaronson, S. A. (1989). Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: Evidence for overexpression in a subset of human mammary tumors. Proc. Natl. Acad. Sci. USA 86, 9193-9197.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 9193-9197
    • Kraus, M.H.1    Issing, W.2    Miki, T.3    Popescu, N.C.4    Aaronson, S.A.5
  • 24
    • 0028059290 scopus 로고
    • E-cadherin null mutant embryos fail to form a trophectoderm epithelium
    • Larue, L., Ohsugi, M., Hirchenhain, J. and Kemler, R. (1994). E-cadherin null mutant embryos fail to form a trophectoderm epithelium. Proc. Natl. Acad. Sci. USA 91, 8263-8267.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 8263-8267
    • Larue, L.1    Ohsugi, M.2    Hirchenhain, J.3    Kemler, R.4
  • 25
    • 0030764771 scopus 로고    scopus 로고
    • Matrix metalloproteinases MMP-2 and MMP-9 are produced in early stages of kidney morphogenesis but only MMP-9 is required for renal organogenesis in vitro
    • Lelongt, B., Trugnan, G., Murphy, G. and Ronco, P. M. (1997). Matrix metalloproteinases MMP-2 and MMP-9 are produced in early stages of kidney morphogenesis but only MMP-9 is required for renal organogenesis in vitro. J. Cell Biol. 136, 1363-1373.
    • (1997) J. Cell Biol. , vol.136 , pp. 1363-1373
    • Lelongt, B.1    Trugnan, G.2    Murphy, G.3    Ronco, P.M.4
  • 26
    • 0032844643 scopus 로고    scopus 로고
    • Selective agenesis of the dorsal pancreas in mice lacking homeobox gene H1xb9
    • Li, H., Arber, S., Jessell, T. M. and Edlund, H. (1999). Selective agenesis of the dorsal pancreas in mice lacking homeobox gene H1xb9. Nat. Genet. 23, 67-70.
    • (1999) Nat. Genet. , vol.23 , pp. 67-70
    • Li, H.1    Arber, S.2    Jessell, T.M.3    Edlund, H.4
  • 27
    • 0027280261 scopus 로고
    • Transforming growth factor-alpha and epidermal growth factor in human fetal gastrointestinal tract
    • Miettinen, P. J. (1993). Transforming growth factor-alpha and epidermal growth factor in human fetal gastrointestinal tract. Ped. Res. 33, 481-486.
    • (1993) Ped. Res. , vol.33 , pp. 481-486
    • Miettinen, P.J.1
  • 28
    • 0029074587 scopus 로고
    • Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor
    • Miettinen, P. J., Berger, J. E., Meneses, J., Phung, V., Pedersen, R., Werb, Z. and Derynck, R. (1995). Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor. Nature 376, 337-341.
    • (1995) Nature , vol.376 , pp. 337-341
    • Miettinen, P.J.1    Berger, J.E.2    Meneses, J.3    Phung, V.4    Pedersen, R.5    Werb, Z.6    Derynck, R.7
  • 29
    • 0032930859 scopus 로고    scopus 로고
    • Epidermal growth factor receptor function is necessary for normal craniofacial development and palate closure
    • Miettinen, P. J., Chin, J. R., Shum, L., Slavkin, H. C., Shuler, C. F., Derynck, R. and Werb, Z. (1999). Epidermal growth factor receptor function is necessary for normal craniofacial development and palate closure. Nat. Genet. 22, 69-73.
    • (1999) Nat. Genet. , vol.22 , pp. 69-73
    • Miettinen, P.J.1    Chin, J.R.2    Shum, L.3    Slavkin, H.C.4    Shuler, C.F.5    Derynck, R.6    Werb, Z.7
  • 30
    • 0026538542 scopus 로고
    • Transforming growth factor alpha and insulin gene expression in human fetal pancreas
    • Miettinen, P. J. and Heikinheimo, K. (1992). Transforming growth factor alpha and insulin gene expression in human fetal pancreas. Development 113, 833-840.
    • (1992) Development , vol.113 , pp. 833-840
    • Miettinen, P.J.1    Heikinheimo, K.2
  • 32
    • 0032476723 scopus 로고    scopus 로고
    • TGF-β plays a key role in morphogenesis of the pancreatic islets of Langerhans by controlling the activity of the matrix metalloproteinase MMP-2
    • Miralles, F., Battelino, T., Czernichow, P. and Scharfmann, R. (1998a). TGF-β plays a key role in morphogenesis of the pancreatic islets of Langerhans by controlling the activity of the matrix metalloproteinase MMP-2. J. Cell Biol. 143, 827-836.
    • (1998) J. Cell Biol. , vol.143 , pp. 827-836
    • Miralles, F.1    Battelino, T.2    Czernichow, P.3    Scharfmann, R.4
  • 33
    • 0031916664 scopus 로고    scopus 로고
    • Follistatin regulates the relative proportions of endocrine versus exocrine tissue during pancreatic development
    • Miralles, F., Chernichow, P. and Scharfmann, R. (1998b). Follistatin regulates the relative proportions of endocrine versus exocrine tissue during pancreatic development. Development 125, 1017-1024.
    • (1998) Development , vol.125 , pp. 1017-1024
    • Miralles, F.1    Chernichow, P.2    Scharfmann, R.3
  • 34
    • 0032991511 scopus 로고    scopus 로고
    • Signaling through fibroblast growth factor receptor 2b plays a key role in the development of the exocrine pancreas
    • Miralles, F., Czernichow, P., Ozaki, K., Itoh, N. and Scharfmann, R. (1999). Signaling through fibroblast growth factor receptor 2b plays a key role in the development of the exocrine pancreas. Proc. Natl. Acad. Sci. USA 96, 6267-6272.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 6267-6272
    • Miralles, F.1    Czernichow, P.2    Ozaki, K.3    Itoh, N.4    Scharfmann, R.5
  • 35
    • 0022553522 scopus 로고
    • Collagenase inhibitor stimulates cleft formation during early morphogenesis of mouse salivary gland
    • Nakanishi, Y., F. Suguira, Kishi, J. I. and Hayakawa, T. (1986). Collagenase inhibitor stimulates cleft formation during early morphogenesis of mouse salivary gland. Dev. Biol. 113, 201-206.
    • (1986) Dev. Biol. , vol.113 , pp. 201-206
    • Nakanishi, Y.1    Suguira, F.2    Kishi, J.I.3    Hayakawa, T.4
  • 36
    • 0030886674 scopus 로고    scopus 로고
    • Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/NeuroD-deficient mice
    • Naya, F. J., Huang, H.-P., Qiu, Y., Mutoh, H., DeMayo, F. J., Leiter, A. B. and Tsai, M.-J. (1997). Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/NeuroD-deficient mice. Genes Dev. 11, 2323-2334.
    • (1997) Genes Dev. , vol.11 , pp. 2323-2334
    • Naya, F.J.1    Huang, H.-P.2    Qiu, Y.3    Mutoh, H.4    DeMayo, F.J.5    Leiter, A.B.6    Tsai, M.-J.7
  • 37
    • 0015446766 scopus 로고
    • An ultrastructural analysis of the developing embryonic pancreasDev. Biol
    • Pictet, R. L., Clark, W. R., Williams, R. H. and Rutter, W. J. (1972). An ultrastructural analysis of the developing embryonic pancreas. Dev. Biol. 29, 436-467.
    • (1972) Dev. Biol , vol.29 , pp. 436-467
    • Pictet, R.L.1    Clark, W.R.2    Williams, R.H.3    Rutter, W.J.4
  • 39
    • 0026668874 scopus 로고
    • Molecular cloning of murine 72-kD type IV collagenase and its expression during mouse development
    • Reponen, P., Sahlberg, C., Huhtala, P., Hurskainen, T., Thesleff, I. and Tryggvason, K. (1992). Molecular cloning of murine 72-kD type IV collagenase and its expression during mouse development. J. Biol. Chem. 267, 7856-7862.
    • (1992) J. Biol. Chem. , vol.267 , pp. 7856-7862
    • Reponen, P.1    Sahlberg, C.2    Huhtala, P.3    Hurskainen, T.4    Thesleff, I.5    Tryggvason, K.6
  • 40
    • 0029118223 scopus 로고
    • The cellular response to neuregulins is governed by complex interactions of the erbB receptor family
    • Riese II, D. J., van Raaij, T. M., Plowman, G. D., Andrews, G. C. and Stern, D. F. (1995). The cellular response to neuregulins is governed by complex interactions of the erbB receptor family. Mol. Cell. Biol. 15, 5770-5776.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 5770-5776
    • Riese D.J. II1    Van Raaij, T.M.2    Plowman, G.D.3    Andrews, G.C.4    Stern, D.F.5
  • 41
    • 0028963661 scopus 로고
    • Activin disrupts epithelial branching morphogenesis in developing glandular organs of the mouse
    • Ritvos, O., Tuuri, T., Erämaa, M., Sainio, K., Hilden, K., Saxen, L. and Gilbert, S. F. (1995). Activin disrupts epithelial branching morphogenesis in developing glandular organs of the mouse. Mech. Dev. 50, 229-245.
    • (1995) Mech. Dev. , vol.50 , pp. 229-245
    • Ritvos, O.1    Tuuri, T.2    Erämaa, M.3    Sainio, K.4    Hilden, K.5    Saxen, L.6    Gilbert, S.F.7
  • 42
    • 0025988037 scopus 로고
    • Uvomorulin mediates calcium-dependent aggregation of islet cells, whereas calcium-independent cell adhesion molecules distinguish between islet cell types
    • Rouiller, D. G., Cirulli, V. and Halban, P. A. (1991). Uvomorulin mediates calcium-dependent aggregation of islet cells, whereas calcium-independent cell adhesion molecules distinguish between islet cell types. Dev. Biol. 148, 233-242.
    • (1991) Dev. Biol. , vol.148 , pp. 233-242
    • Rouiller, D.G.1    Cirulli, V.2    Halban, P.A.3
  • 43
    • 0019450328 scopus 로고
    • Radial caseinolysis in agarose: A simple method for detection of plasminogen activator activity in the presence of inhibitory substances and serum
    • Saksela, O. (1981). Radial caseinolysis in agarose: a simple method for detection of plasminogen activator activity in the presence of inhibitory substances and serum. Anal. Biochem. 111, 276-282.
    • (1981) Anal. Biochem. , vol.111 , pp. 276-282
    • Saksela, O.1
  • 45
    • 0025297086 scopus 로고
    • Overexpression of TGFα in transgenic mice: Induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast
    • Sandgren, E. P., Luetteke, N. C., Palmiter, R. D., Brinster, R. L. and Lee, D. L. (1990). Overexpression of TGFα in transgenic mice: Induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast. Cell 61, 1121-1135.
    • (1990) Cell , vol.61 , pp. 1121-1135
    • Sandgren, E.P.1    Luetteke, N.C.2    Palmiter, R.D.3    Brinster, R.L.4    Lee, D.L.5
  • 46
    • 0023574174 scopus 로고
    • Embryonic kidney in organ culture
    • Saxén, L. and Lehtonen, E. (1987). Embryonic kidney in organ culture. Differentiation 36, 2-11.
    • (1987) Differentiation , vol.36 , pp. 2-11
    • Saxén, L.1    Lehtonen, E.2
  • 47
    • 0026793456 scopus 로고
    • Growth factor signaling by receptor tyrosine kinases
    • Schlessinger, J. and Ulrich, A. (1992). Growth factor signaling by receptor tyrosine kinases. Neuron 9, 383-391.
    • (1992) Neuron , vol.9 , pp. 383-391
    • Schlessinger, J.1    Ulrich, A.2
  • 48
    • 0032472938 scopus 로고    scopus 로고
    • A strain-independent postnatal neurodegeneration in mice lacking the EGF receptor
    • Sibilia, M., Steinbach, J. P., Stingl, L., Aguzzi, A. and Wagner, E. F. (1998). A strain-independent postnatal neurodegeneration in mice lacking the EGF receptor. EMBO J. 17, 719-731.
    • (1998) EMBO J. , vol.17 , pp. 719-731
    • Sibilia, M.1    Steinbach, J.P.2    Stingl, L.3    Aguzzi, A.4    Wagner, E.F.5
  • 49
    • 0029045856 scopus 로고
    • Strain-dependent epithelial defects in mice lacking EGF receptor
    • Sibilia, M. and Wagner, E. (1995). Strain-dependent epithelial defects in mice lacking EGF receptor. Science 269, 234-238.
    • (1995) Science , vol.269 , pp. 234-238
    • Sibilia, M.1    Wagner, E.2
  • 50
    • 0030897629 scopus 로고    scopus 로고
    • The Pax4 gene is essential for differentiation of insulin-producing beta-cells in the mammalian pancreas
    • Sosa-Pineda, B., Chowdhury, K., Torres, M., Oliver, G. and Gruss, P. (1997). The Pax4 gene is essential for differentiation of insulin-producing beta-cells in the mammalian pancreas. Nature 386, 399-402.
    • (1997) Nature , vol.386 , pp. 399-402
    • Sosa-Pineda, B.1    Chowdhury, K.2    Torres, M.3    Oliver, G.4    Gruss, P.5
  • 51
    • 0029745109 scopus 로고    scopus 로고
    • The serpin PAI-1 inhibits cell migration by blocking integrin alpha V beta 3 binding to vitronectin
    • Stefansson, S. and Lawrence, D. A. (1996). The serpin PAI-1 inhibits cell migration by blocking integrin alpha V beta 3 binding to vitronectin. Nature 383, 441-443.
    • (1996) Nature , vol.383 , pp. 441-443
    • Stefansson, S.1    Lawrence, D.A.2
  • 52
    • 0030914931 scopus 로고    scopus 로고
    • Pax6 is required for differentiation of glucagon-producing alpha-cells in mouse pancreas
    • St-Onge, L., Sosa-Pineda, B., Chowdhury, K., Mansouri, A. and Gruss, P. (1997). Pax6 is required for differentiation of glucagon-producing alpha-cells in mouse pancreas. Nature 387, 406-409.
    • (1997) Nature , vol.387 , pp. 406-409
    • St-Onge, L.1    Sosa-Pineda, B.2    Chowdhury, K.3    Mansouri, A.4    Gruss, P.5
  • 53
    • 0025894092 scopus 로고
    • Cadherin cell adhesion receptors as a morphogenetic regulator
    • Takeichi, M. (1991). Cadherin cell adhesion receptors as a morphogenetic regulator. Science 251, 1451-1455.
    • (1991) Science , vol.251 , pp. 1451-1455
    • Takeichi, M.1
  • 54
    • 0029160437 scopus 로고
    • Morphogenetic roles of classic cadherins
    • Takeichi, M. (1995). Morphogenetic roles of classic cadherins. Curr. Opin. Cell Biol. 7, 619-627.
    • (1995) Curr. Opin. Cell Biol. , vol.7 , pp. 619-627
    • Takeichi, M.1
  • 56
    • 0031040649 scopus 로고    scopus 로고
    • Gelatinases and inhibitors of gelatinases in pancreatic islets and islet cell tumors
    • Tomita, T. and Iwata, K. (1997). Gelatinases and inhibitors of gelatinases in pancreatic islets and islet cell tumors. Mod. Pathol. 10, 47-54.
    • (1997) Mod. Pathol. , vol.10 , pp. 47-54
    • Tomita, T.1    Iwata, K.2
  • 57
    • 0031607523 scopus 로고    scopus 로고
    • EGF and IL-1 alpha modulate the release of collagenase, gelatinase and TIMP-1 as well as the release of calcium by rabbit calvarial bone explants
    • van der Zee, E., Jansen, I., Hoeben, K., Beertsen, W. and Everts, V. (1998). EGF and IL-1 alpha modulate the release of collagenase, gelatinase and TIMP-1 as well as the release of calcium by rabbit calvarial bone explants. J. Periodontal. Res. 33, 65-72.
    • (1998) J. Periodontal. Res. , vol.33 , pp. 65-72
    • Van Der Zee, E.1    Jansen, I.2    Hoeben, K.3    Beertsen, W.4    Everts, V.5
  • 58
    • 0030977539 scopus 로고    scopus 로고
    • Transcription factor AP-2 controls transcription of the human transforming growth factor-α gene
    • Wang, D., Shin, T. H. and Kudlow, J. E. (1997). Transcription factor AP-2 controls transcription of the human transforming growth factor-α gene. J. Biol. Chem. 272, 14244-14250.
    • (1997) J. Biol. Chem. , vol.272 , pp. 14244-14250
    • Wang, D.1    Shin, T.H.2    Kudlow, J.E.3
  • 59
    • 0026604786 scopus 로고
    • Epigenetic role of epidermal growth factor expression and signalling in embryonic mouse lung morphogenesis
    • Warburton, D., Seth, R., Shum, L., Horcher, P. G., Hall, F. L., Werb, Z. and Slavkin, H. C. (1992). Epigenetic role of epidermal growth factor expression and signalling in embryonic mouse lung morphogenesis. Dev. Biol. 149, 123-133.
    • (1992) Dev. Biol. , vol.149 , pp. 123-133
    • Warburton, D.1    Seth, R.2    Shum, L.3    Horcher, P.G.4    Hall, F.L.5    Werb, Z.6    Slavkin, H.C.7
  • 61
    • 0030715322 scopus 로고    scopus 로고
    • ECM and cell surface proteolysis: Regulating cellular ecology
    • Werb, Z. (1997). ECM and cell surface proteolysis: regulating cellular ecology. Cell 91, 439-442.
    • (1997) Cell , vol.91 , pp. 439-442
    • Werb, Z.1
  • 62
    • 0032957973 scopus 로고    scopus 로고
    • Signalling through the stromal epidermal growth factor receptor is necessary for mammary ductal development
    • Wiesen, J. F., Young, P., Werb, Z. and Cunha, G. R. (1999). Signalling through the stromal epidermal growth factor receptor is necessary for mammary ductal development. Development 126, 335-344.
    • (1999) Development , vol.126 , pp. 335-344
    • Wiesen, J.F.1    Young, P.2    Werb, Z.3    Cunha, G.R.4


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