High glucose transactivates the EGF receptor and up-regulates serum glucocorticoid kinase in the proximal tubule

Kidney International

Volumn 68, Issue 3, 2005, Pages 985-997

  Saad, Sonia ^b   Stevens, Veronica A ^b   Wassef, Lesley ^b   Poronnik, Philip ^b   Kelly, Darren J ^b   Gilbert, Richard E ^b   Pollock, Carol A ^a  

^a ROYAL NORTH SHORE HOSPITAL   (Australia)

^b NONE

Author keywords

EGFR; High glucose; Proximal tubule; SGK

Indexed keywords

6 (4 HYDROXYPHENYL) 4 (ALPHA METHYLBENZYLAMINO) 7H PYRROLO[2,3 D]PYRIMIDINE; EPIDERMAL GROWTH FACTOR RECEPTOR; GLUCOCORTICOID REGULATED KINASE; GLUCOSE; MESSENGER RNA; PROTEIN SERINE THREONINE KINASE; SODIUM PROTON EXCHANGE PROTEIN 3; STREPTOZOCIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL CYCLE; CELL GROWTH; CONTROLLED STUDY; DIABETIC NEPHROPATHY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ASSAY; GENE OVEREXPRESSION; GLUCOSE HOMEOSTASIS; GLUCOSE METABOLISM; HUMAN; HUMAN CELL; KIDNEY PROXIMAL TUBULE; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; STREPTOZOCIN DIABETES; TRANSACTIVATION; UPREGULATION;

ANIMALS; CELLS, CULTURED; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; DIABETIC NEPHROPATHIES; EPIDERMAL GROWTH FACTOR; GLUCOSE; HUMANS; IMMEDIATE-EARLY PROTEINS; KIDNEY TUBULES, PROXIMAL; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RATS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RNA, MESSENGER; SODIUM-HYDROGEN ANTIPORTER; UP-REGULATION;

EID: 32644481587     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1111/j.1523-1755.2005.00492.x     Document Type: Article

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