메뉴 건너뛰기




Volumn 51, Issue 1, 1997, Pages 19-37

The neurotrophic action and signalling of epidermal growth factor

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR;

EID: 0031044540     PISSN: 03010082     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0301-0082(96)00046-9     Document Type: Review
Times cited : (178)

References (236)
  • 1
    • 0025872560 scopus 로고
    • Epidermal growth factor enhances short-term potentiation and facilitates induction of long-term potentiation in rat hippocampal slices
    • Abe, K., Xie, F. J. and Saito, H. (1991) Epidermal growth factor enhances short-term potentiation and facilitates induction of long-term potentiation in rat hippocampal slices. Brain Res. 547, 171-174.
    • (1991) Brain Res. , vol.547 , pp. 171-174
    • Abe, K.1    Xie, F.J.2    Saito, H.3
  • 2
    • 0026671937 scopus 로고
    • 2+ concentration in rat hippocampal neurons
    • 2+ concentration in rat hippocampal neurons. Brain Res. 587, 102-108.
    • (1992) Brain Res. , vol.587 , pp. 102-108
    • Abe, K.1    Saito, H.2
  • 4
    • 0021238582 scopus 로고
    • The ontogeny of epidermal growth factor receptors during mouse development
    • Adamson, E. D. and Meek, J. (1984) The ontogeny of epidermal growth factor receptors during mouse development. Dev. Biol. 103, 62-70.
    • (1984) Dev. Biol. , vol.103 , pp. 62-70
    • Adamson, E.D.1    Meek, J.2
  • 5
    • 0022416671 scopus 로고
    • Epidermal growth factor and bovine growth hormone stimulate differentiation and myelination of brain cell aggregates in culture
    • Almazan, G., Honegger, P., Matthieu, J. M. and Guentert-Lauber, B. (1985) Epidermal growth factor and bovine growth hormone stimulate differentiation and myelination of brain cell aggregates in culture. Brain Res. 353, 257-264.
    • (1985) Brain Res. , vol.353 , pp. 257-264
    • Almazan, G.1    Honegger, P.2    Matthieu, J.M.3    Guentert-Lauber, B.4
  • 6
    • 0020380822 scopus 로고
    • Morphological development of the rat cerebellum and some of its mechanisms
    • Altman, J. (1982) Morphological development of the rat cerebellum and some of its mechanisms. Exp. Brain Res. [Suppl.] 6, 8-46.
    • (1982) Exp. Brain Res. , vol.6 , Issue.SUPPL. , pp. 8-46
    • Altman, J.1
  • 7
    • 0025871767 scopus 로고
    • Pro-leu-Ser/ Thr-Pro is a consensus primary sequence for substrate protein phosphorylation. Characterization of the phosphorylation of c-myc and c-jun proteins by an epidermal growth factor receptor threonine 669 protein kinase
    • Alvarez, E., Northwood, I. C., Gonzalez, F. A., Latour, D. A., Seth, A., Abate, C., Curran. T. and Davis, R. J. (1991) Pro-Leu-Ser/ Thr-Pro is a consensus primary sequence for substrate protein phosphorylation. Characterization of the phosphorylation of c-myc and c-jun proteins by an epidermal growth factor receptor threonine 669 protein kinase. J. Biol. Chem. 266, 15277-15285.
    • (1991) J. Biol. Chem. , vol.266 , pp. 15277-15285
    • Alvarez, E.1    Northwood, I.C.2    Gonzalez, F.A.3    Latour, D.A.4    Seth, A.5    Abate, C.6    Curran, T.7    Davis, R.J.8
  • 8
    • 0025823975 scopus 로고
    • EGF and TGF-α stimulate retinal neuroepithelial cell proliferation in vitro
    • Anchan, R. M., Reh, T. A., Angello, J., Balliet, A. and Walker, M. (1991) EGF and TGF-α stimulate retinal neuroepithelial cell proliferation in vitro. Neuron 6, 923-936.
    • (1991) Neuron , vol.6 , pp. 923-936
    • Anchan, R.M.1    Reh, T.A.2    Angello, J.3    Balliet, A.4    Walker, M.5
  • 9
    • 0025681492 scopus 로고
    • Binding of SH2 domains of phospholipase C gamma 1, GAP, and Src to activated growth factor receptors
    • Anderson, D.. Koch. C. A., Grey, L., Ellis, C.. Moran. M. F. and Pawson, T. (1990) Binding of SH2 domains of phospholipase C gamma 1, GAP, and Src to activated growth factor receptors. Science 250, 979-982.
    • (1990) Science , vol.250 , pp. 979-982
    • Anderson, D.1    Koch, C.A.2    Grey, L.3    Ellis, C.4    Moran, M.F.5    Pawson, T.6
  • 10
    • 0009518290 scopus 로고
    • Sarcoma growth factor from conditioned medium of virally transformed cells is composed of both type alpha and type beta transforming growth factors
    • Anzano, M. A., Roberts, A. B., Smith, J. M., Sporn, M. B. and De Larco, J. E. (1983) Sarcoma growth factor from conditioned medium of virally transformed cells is composed of both type alpha and type beta transforming growth factors. Proc. Natl. Acad. Sci. U. S. A. 80, 6264-6268.
    • (1983) Proc. Natl. Acad. Sci. U. S. A. , vol.80 , pp. 6264-6268
    • Anzano, M.A.1    Roberts, A.B.2    Smith, J.M.3    Sporn, M.B.4    De Larco, J.E.5
  • 11
    • 0025605344 scopus 로고
    • The let-23 gene necessary for Caenorhabditis elegans vulval induction encodes a tyrosine kinase of the EGF receptor subfamily
    • Aroian, R. V., Koga, M., Mendel, J. E., Ohshima, Y. and Sternberg, P. W. (1990) The let-23 gene necessary for Caenorhabditis elegans vulval induction encodes a tyrosine kinase of the EGF receptor subfamily. Nature 348, 693-699.
    • (1990) Nature , vol.348 , pp. 693-699
    • Aroian, R.V.1    Koga, M.2    Mendel, J.E.3    Ohshima, Y.4    Sternberg, P.W.5
  • 12
    • 0024601010 scopus 로고
    • PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells
    • Auger, K. R., Serunian, L. A., Soltoff, S. P., Libby, P. and Cantley, L. C. (1989) PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells. Cell 57, 167-175.
    • (1989) Cell , vol.57 , pp. 167-175
    • Auger, K.R.1    Serunian, L.A.2    Soltoff, S.P.3    Libby, P.4    Cantley, L.C.5
  • 14
    • 0029968294 scopus 로고    scopus 로고
    • Epidermal growth factor-mediated inhibition of neurotransmitter glutamate release from rat forebrain synaptosomes
    • Barrie, A., Chieregatti, E., Miloso, M., Benfenati, R. and Valtorta, F. (1996) Epidermal growth factor-mediated inhibition of neurotransmitter glutamate release from rat forebrain synaptosomes. Mol. Pharmacol. 49, 399-403.
    • (1996) Mol. Pharmacol. , vol.49 , pp. 399-403
    • Barrie, A.1    Chieregatti, E.2    Miloso, M.3    Benfenati, R.4    Valtorta, F.5
  • 15
    • 0028040812 scopus 로고
    • Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor
    • Batzer, A. G., Rotin, D., Urena, J. M., Skolnik, E. Y. and Schlessinger, J. (1994) Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor. Mol. Cell Biol. 14, 5192-5201.
    • (1994) Mol. Cell Biol. , vol.14 , pp. 5192-5201
    • Batzer, A.G.1    Rotin, D.2    Urena, J.M.3    Skolnik, E.Y.4    Schlessinger, J.5
  • 16
    • 0028823802 scopus 로고
    • Neu differentiation factor activation of ErbB-3 and ErbB-4 is cell specific and displays a differential requirement for ErbB-2
    • Beerli, R. R., Graus-Porta, D., Woods-Cook, K., Chen, X. M., Yarden, Y. and Hynes, N. E. (1995) Neu differentiation factor activation of ErbB-3 and ErbB-4 is cell specific and displays a differential requirement for ErbB-2. Mol. Cell. Biol. 15, 6496-6505.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 6496-6505
    • Beerli, R.R.1    Graus-Porta, D.2    Woods-Cook, K.3    Chen, X.M.4    Yarden, Y.5    Hynes, N.E.6
  • 17
    • 0342642836 scopus 로고
    • Phorbol esters induce transient internalization without degradation of unoccupied epidermal growth factor receptors
    • Beguinot. L.. Hanover, J. A., Ito, S., Richert, N. D., Willingham, M. C. and Pastan, I. (1985) Phorbol esters induce transient internalization without degradation of unoccupied epidermal growth factor receptors. Proc. Natl. Acad. Sci. U. S. A. 82, 2774-2778.
    • (1985) Proc. Natl. Acad. Sci. U. S. A. , vol.82 , pp. 2774-2778
    • Beguinot, L.1    Hanover, J.A.2    Ito, S.3    Richert, N.D.4    Willingham, M.C.5    Pastan, I.6
  • 18
    • 0021750054 scopus 로고
    • Inositol trisphosphate, a novel second messenger in cellular signal transduction
    • Berridge, M. J. and Irvine. R. F. (1984) Inositol trisphosphate, a novel second messenger in cellular signal transduction. Nature 312, 315-321.
    • (1984) Nature , vol.312 , pp. 315-321
    • Berridge, M.J.1    Irvine, R.F.2
  • 19
    • 0025819499 scopus 로고
    • The sequences of the human and mouse c-cbl proto-oncogenes show v-cbl was generated by a large truncation encompassing a proline-rich domain and a leucine zipper-like motif
    • Blake. T. J., Shapiro, M., Morse, H. C. III and Langdon, W. Y. (1991) The sequences of the human and mouse c-cbl proto-oncogenes show v-cbl was generated by a large truncation encompassing a proline-rich domain and a leucine zipper-like motif. Oncogene 6, 653-657.
    • (1991) Oncogene , vol.6 , pp. 653-657
    • Blake, T.J.1    Shapiro, M.2    Morse H.C. III3    Langdon, W.Y.4
  • 20
    • 0027215275 scopus 로고
    • The truncation that generated the v-cbl oncogene reveals an ability for nuclear transport, DNA binding and acute transformation
    • Blake, T. J., Heath, K. G. and Langdon, W. Y. (1993) The truncation that generated the v-cbl oncogene reveals an ability for nuclear transport, DNA binding and acute transformation. EMBO J. 12, 2017-2026.
    • (1993) EMBO J. , vol.12 , pp. 2017-2026
    • Blake, T.J.1    Heath, K.G.2    Langdon, W.Y.3
  • 21
    • 0027732538 scopus 로고
    • Proteins regulating Ras and its relatives
    • Boguski, M. S. and McCormick, F. (1993) Proteins regulating Ras and its relatives. Nature 366, 643-654.
    • (1993) Nature , vol.366 , pp. 643-654
    • Boguski, M.S.1    McCormick, F.2
  • 22
    • 0025144604 scopus 로고
    • The epidermal growth factor precursor isolated from murine kidney membranes. Chemical characterization and biological properties
    • Breyer, J. A. and Cohen, S. (1990) The epidermal growth factor precursor isolated from murine kidney membranes. Chemical characterization and biological properties. J. Biol. Chem. 265, 16564-16570.
    • (1990) J. Biol. Chem. , vol.265 , pp. 16564-16570
    • Breyer, J.A.1    Cohen, S.2
  • 23
    • 0027153103 scopus 로고
    • Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor
    • Buday, L. and Downward, J. (1993) Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor. Cell 73, 611-620.
    • (1993) Cell , vol.73 , pp. 611-620
    • Buday, L.1    Downward, J.2
  • 24
  • 25
    • 0023082137 scopus 로고
    • Receptors for epidermal growth factor and other polypeptide mitogens
    • Carpenter, G. (1987) Receptors for epidermal growth factor and other polypeptide mitogens. Ann. Rev. Biochem. 56, 881-914.
    • (1987) Ann. Rev. Biochem. , vol.56 , pp. 881-914
    • Carpenter, G.1
  • 28
    • 0028176477 scopus 로고
    • A neu acquaintance for erbB3 and erbB4: A role for receptor heterodimenzation in growth signaling
    • Carraway, K. L. and Cantley, L. C. (1994) A neu acquaintance for erbB3 and erbB4: a role for receptor heterodimenzation in growth signaling. Cell 78, 5-8.
    • (1994) Cell , vol.78 , pp. 5-8
    • Carraway, K.L.1    Cantley, L.C.2
  • 29
    • 0025950026 scopus 로고
    • EGF enhances the survival of dopamine neurons in rat embryonic mesencephalon primary cell culture
    • Casper, D., Mytilineou, C. and Blum, M. (1991) EGF enhances the survival of dopamine neurons in rat embryonic mesencephalon primary cell culture. J. Neurosci. Res. 30, 372-381.
    • (1991) J. Neurosci. Res. , vol.30 , pp. 372-381
    • Casper, D.1    Mytilineou, C.2    Blum, M.3
  • 30
    • 0028363762 scopus 로고
    • Epidermal growth factor and basic fibroblast growth factor have independent actions on mesencephalic dopamine neurons in culture
    • Casper, D., Roboz, G. J. and Blum, M. (1994) Epidermal growth factor and basic fibroblast growth factor have independent actions on mesencephalic dopamine neurons in culture. J. Neurochem. 62, 2166-2177.
    • (1994) J. Neurochem. , vol.62 , pp. 2166-2177
    • Casper, D.1    Roboz, G.J.2    Blum, M.3
  • 31
    • 0029131524 scopus 로고
    • Epidermal growth factor and basic fibroblast growth factor protect dopaminergic neurons from glutamate toxicity in culture
    • Casper, D. and Blum, M. (1995) Epidermal growth factor and basic fibroblast growth factor protect dopaminergic neurons from glutamate toxicity in culture. J. Neurochem. 65, 1016-1026.
    • (1995) J. Neurochem. , vol.65 , pp. 1016-1026
    • Casper, D.1    Blum, M.2
  • 32
    • 0026578026 scopus 로고
    • Growth factor signaling: Where is the specificity?
    • Chao, M. V. (1992) Growth factor signaling: where is the specificity?. Cell 68, 995-997.
    • (1992) Cell , vol.68 , pp. 995-997
    • Chao, M.V.1
  • 34
    • 0021336733 scopus 로고
    • C-kinase phosphorylates the epidermal growth factor receptor and reduces its epidermal growth factor-stimulated tyrosine protein kinase activity
    • Cochet, C., Gill, G. N., Meisenhelder, J., Cooper, J. A. and Hunter, T. (1984) C-kinase phosphorylates the epidermal growth factor receptor and reduces its epidermal growth factor-stimulated tyrosine protein kinase activity. J. Biol. Chem. 259, 2553-2558.
    • (1984) J. Biol. Chem. , vol.259 , pp. 2553-2558
    • Cochet, C.1    Gill, G.N.2    Meisenhelder, J.3    Cooper, J.A.4    Hunter, T.5
  • 35
    • 0026067488 scopus 로고
    • Interaction between the epidermal growth factor receptor and phosphoinositide kinases
    • Cochet, C., Filhol, O., Payrastre, B., Hunter, T. and Gill, G. N. (1991) Interaction between the epidermal growth factor receptor and phosphoinositide kinases. J. Biol. Chem. 266, 637-644.
    • (1991) J. Biol. Chem. , vol.266 , pp. 637-644
    • Cochet, C.1    Filhol, O.2    Payrastre, B.3    Hunter, T.4    Gill, G.N.5
  • 36
    • 0026468420 scopus 로고
    • Inositol-lipid-specific phospholipase C isoenzymes and their differential regulation by receptors
    • Cockcroft, S. and Thomas, G. M. (1992) Inositol-lipid-specific phospholipase C isoenzymes and their differential regulation by receptors. Biochem. J. 288, 1-14.
    • (1992) Biochem. J. , vol.288 , pp. 1-14
    • Cockcroft, S.1    Thomas, G.M.2
  • 37
    • 0028895654 scopus 로고
    • Modular binding domains in signal transduction proteins
    • Cohen, G. B., Ren, R. and Baltimore, D. (1995) Modular binding domains in signal transduction proteins. Cell 80, 237-248.
    • (1995) Cell , vol.80 , pp. 237-248
    • Cohen, G.B.1    Ren, R.2    Baltimore, D.3
  • 38
    • 84916265276 scopus 로고
    • Isolation of a mouse submaxillary gland protein accelerating incisor eruption and eyelid opening in the new-born animal
    • Cohen, S. (1962) Isolation of a mouse submaxillary gland protein accelerating incisor eruption and eyelid opening in the new-born animal. J. Biol. Chem. 237, 1555-1562.
    • (1962) J. Biol. Chem. , vol.237 , pp. 1555-1562
    • Cohen, S.1
  • 39
    • 0013825447 scopus 로고
    • The stimulation of epidermal proliferation by a specific protein (EGF)
    • Cohen, S. (1965) The stimulation of epidermal proliferation by a specific protein (EGF). Dev. Biol. 12, 394-407.
    • (1965) Dev. Biol. , vol.12 , pp. 394-407
    • Cohen, S.1
  • 40
    • 0001895889 scopus 로고
    • The stimulation of epideral keratinization by a protein isolated from the submaxillary gland of the mouse
    • Cohen, S. and Elliott, G. A. (1963) The stimulation of epideral keratinization by a protein isolated from the submaxillary gland of the mouse. J. Invest. Dermatol. 40, 1-5.
    • (1963) J. Invest. Dermatol. , vol.40 , pp. 1-5
    • Cohen, S.1    Elliott, G.A.2
  • 41
    • 0027456990 scopus 로고
    • In vivo binding properties of SH2 domains from GTPase-activating protein and phosphatidylinositol 3-kinase
    • Cooper, J. A. and Kashishian, A. (1993) In vivo binding properties of SH2 domains from GTPase-activating protein and phosphatidylinositol 3-kinase. Mol. Cell Biol. 13, 1737-1745.
    • (1993) Mol. Cell Biol. , vol.13 , pp. 1737-1745
    • Cooper, J.A.1    Kashishian, A.2
  • 42
    • 0028855446 scopus 로고
    • Differential expression of ARIA isoforms in the rat brain
    • Corfas, G., Rosen, K. M., Aratake, H., Krauss, R. and Fischbach, G. D. (1995) Differential expression of ARIA isoforms in the rat brain. Neuron 14, 103-115.
    • (1995) Neuron , vol.14 , pp. 103-115
    • Corfas, G.1    Rosen, K.M.2    Aratake, H.3    Krauss, R.4    Fischbach, G.D.5
  • 43
    • 0028228616 scopus 로고
    • Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells
    • Cowley, S., Paterson, H., Kemp, P. and Marshall, C. J. (1994) Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells. Cell 77, 841-852.
    • (1994) Cell , vol.77 , pp. 841-852
    • Cowley, S.1    Paterson, H.2    Kemp, P.3    Marshall, C.J.4
  • 44
    • 0027304607 scopus 로고
    • Extracellular signals and reversible protein phosphorylation: What to Mek of it all
    • Crews, C. M. and Erikson, R. L. (1993) Extracellular signals and reversible protein phosphorylation: what to Mek of it all. Cell 74, 215-217.
    • (1993) Cell , vol.74 , pp. 215-217
    • Crews, C.M.1    Erikson, R.L.2
  • 45
    • 0028234529 scopus 로고
    • Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
    • Darnell, J. E. Jr., Kerr, I. M. and Stark, G. R. (1994) Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 264, 1415-1421.
    • (1994) Science , vol.264 , pp. 1415-1421
    • Darnell J.E., Jr.1    Kerr, I.M.2    Stark, G.R.3
  • 46
    • 0030044360 scopus 로고    scopus 로고
    • Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors
    • Daub, H., Weiss, F. U., Wallasch, C. and Ulrich, A. (1996) Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors. Nature 379, 557-560.
    • (1996) Nature , vol.379 , pp. 557-560
    • Daub, H.1    Weiss, F.U.2    Wallasch, C.3    Ulrich, A.4
  • 47
    • 0023807364 scopus 로고
    • Transforming growth factor
    • Derynck, R. (1988) Transforming growth factor. Cell 54, 593-595.
    • (1988) Cell , vol.54 , pp. 593-595
    • Derynck, R.1
  • 48
  • 50
    • 0029021518 scopus 로고
    • Heterodimerization and functional interaction between EGF receptor family members: A new signaling paradigm with implications for breast cancer research
    • Earp, H. S., Dawson, T. L., Li, X. and Yu, H. (1995) Heterodimerization and functional interaction between EGF receptor family members: A new signaling paradigm with implications for breast cancer research. Breast Cancer Res. Treat. 35, 115-132.
    • (1995) Breast Cancer Res. Treat. , vol.35 , pp. 115-132
    • Earp, H.S.1    Dawson, T.L.2    Li, X.3    Yu, H.4
  • 51
    • 0027910431 scopus 로고
    • Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation
    • Egan, S. E., Giddings, B. W., Brooks, M. W., Buday, L., Sizeland, A. M. and Weinberg, R. A. (1993) Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation. Nature 363, 45-51.
    • (1993) Nature , vol.363 , pp. 45-51
    • Egan, S.E.1    Giddings, B.W.2    Brooks, M.W.3    Buday, L.4    Sizeland, A.M.5    Weinberg, R.A.6
  • 52
    • 0025177324 scopus 로고
    • Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases
    • Ellis, C., Moran, M., McCormick, F. and Pawson, T. (1990) Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases. Nature 343, 377-381.
    • (1990) Nature , vol.343 , pp. 377-381
    • Ellis, C.1    Moran, M.2    McCormick, F.3    Pawson, T.4
  • 54
    • 0025689317 scopus 로고
    • High oxygen atmosphere for neuronal cell culture with nerve growth factor. II. Survival and growth of clonal rat pheochromocytoma PC12h cells
    • Enokido, Y. and Hatanaka, H. (1990) High oxygen atmosphere for neuronal cell culture with nerve growth factor. II. Survival and growth of clonal rat pheochromocytoma PC12h cells. Brain Res. 536, 23-29.
    • (1990) Brain Res. , vol.536 , pp. 23-29
    • Enokido, Y.1    Hatanaka, H.2
  • 55
    • 0025727594 scopus 로고
    • cDNA cloning of a novel 85 kd protein that has SH2 domains and regulates binding of PI3-kinase to the PDGF β-receptor
    • Escobedo. J. A., Navankasattusas, S., Kavanaugh, W. M., Milfay, D., Fried, V. A. and Williams, L. T. (1991) cDNA cloning of a novel 85 kd protein that has SH2 domains and regulates binding of PI3-kinase to the PDGF β-receptor. Cell 65, 75-82.
    • (1991) Cell , vol.65 , pp. 75-82
    • Escobedo, J.A.1    Navankasattusas, S.2    Kavanaugh, W.M.3    Milfay, D.4    Fried, V.A.5    Williams, L.T.6
  • 56
    • 0021279260 scopus 로고
    • Epidermal growth factor immunoreactive material in the central nervous system: Location and development
    • Fallon, J. H., Seroogy, K. B., Loughlin, S. E., Morrison, R. S., Bradshaw, R. A., Knaver, D. J. and Cunningham, D. D. (1984) Epidermal growth factor immunoreactive material in the central nervous system: location and development. Science 224, 1107-1109.
    • (1984) Science , vol.224 , pp. 1107-1109
    • Fallon, J.H.1    Seroogy, K.B.2    Loughlin, S.E.3    Morrison, R.S.4    Bradshaw, R.A.5    Knaver, D.J.6    Cunningham, D.D.7
  • 57
    • 0027526321 scopus 로고
    • ARIA, a protein that stimulates acetylcholine receptor synthesis, is a member of the neu ligand family
    • Falls, D. L., Rosen, K. M., Corfas, G., Lane, W. S. and Fischbach, G. D. (1993) ARIA, a protein that stimulates acetylcholine receptor synthesis, is a member of the neu ligand family. Cell 72, 801-815.
    • (1993) Cell , vol.72 , pp. 801-815
    • Falls, D.L.1    Rosen, K.M.2    Corfas, G.3    Lane, W.S.4    Fischbach, G.D.5
  • 58
    • 0026657462 scopus 로고
    • Epidermal growth factor receptor in synaptic fractions of the rat central nervous system
    • Faundez, V., Krauss, R., Holuigue, L., Garrido, J. and Gonzalez, A. (1992) Epidermal growth factor receptor in synaptic fractions of the rat central nervous system. J. Biol. Chem. 267, 20363-20370.
    • (1992) J. Biol. Chem. , vol.267 , pp. 20363-20370
    • Faundez, V.1    Krauss, R.2    Holuigue, L.3    Garrido, J.4    Gonzalez, A.5
  • 59
    • 0027531637 scopus 로고
    • SH2-containing phosphotyrosine phosphatase as a target of protein-tyrosine kinases
    • Feng, G. S., Hui, C. C. and Pawson, T. (1993) SH2-containing phosphotyrosine phosphatase as a target of protein-tyrosine kinases. Science 259, 1607-1611.
    • (1993) Science , vol.259 , pp. 1607-1611
    • Feng, G.S.1    Hui, C.C.2    Pawson, T.3
  • 60
    • 0028047349 scopus 로고
    • Phosphotyrosine phosphatases with SH2 domains: Regulators of signal transduction
    • Feng, G. S. and Pawson, T. (1994) Phosphotyrosine phosphatases with SH2 domains: regulators of signal transduction. Trends. Genet. 10, 54-58.
    • (1994) Trends. Genet. , vol.10 , pp. 54-58
    • Feng, G.S.1    Pawson, T.2
  • 61
    • 0025751578 scopus 로고
    • Epidermal growth factor exerts neuronotrophic effects on dopaminergic and GABAergic CNS neurons: Comparison with basic fibroblast growth factor
    • Ferrari. G., Toffano, G. and Skaper, S. D. (1991) Epidermal growth factor exerts neuronotrophic effects on dopaminergic and GABAergic CNS neurons: comparison with basic fibroblast growth factor. J. Neurosci. Res. 30, 493-497.
    • (1991) J. Neurosci. Res. , vol.30 , pp. 493-497
    • Ferrari, G.1    Toffano, G.2    Skaper, S.D.3
  • 63
    • 0026502059 scopus 로고
    • Inositol lipids and signal transduction in the nervous system: An update
    • Fisher, S. K., Heacock, A. M. and Agranoff, B. W. (1992) Inositol lipids and signal transduction in the nervous system: an update. J. Neurochem. 58, 18-38.
    • (1992) J. Neurochem. , vol.58 , pp. 18-38
    • Fisher, S.K.1    Heacock, A.M.2    Agranoff, B.W.3
  • 64
    • 0029166095 scopus 로고
    • Distribution of erb-B2, erb-B3, and erb-B4 in the developing avian nervous system
    • Francoeur. J. R., Richardson, P. M., Dunn, R. J. and Carbonetto, S. (1995) Distribution of erb-B2, erb-B3, and erb-B4 in the developing avian nervous system. J. Neurosci. Res. 41, 836-845.
    • (1995) J. Neurosci. Res. , vol.41 , pp. 836-845
    • Francoeur, J.R.1    Richardson, P.M.2    Dunn, R.J.3    Carbonetto, S.4
  • 65
    • 0029079275 scopus 로고
    • The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase
    • Franke, T. F., Yang, S. I., Chan. T. O., Datta, K., Kazlauskas, A., Morrison, D. K., Kaplan, D. R. and Tsichlis, P. N. (1995) The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase. Cell 81, 727-736.
    • (1995) Cell , vol.81 , pp. 727-736
    • Franke, T.F.1    Yang, S.I.2    Chan, T.O.3    Datta, K.4    Kazlauskas, A.5    Morrison, D.K.6    Kaplan, D.R.7    Tsichlis, P.N.8
  • 66
    • 0027372119 scopus 로고
    • Transcription factor p91 interacts with the epidermal growth factor receptor and mediates activation of the c-fos gene promoter
    • Fu, X. Y. and Zhang, J. J. (1993) Transcription factor p91 interacts with the epidermal growth factor receptor and mediates activation of the c-fos gene promoter. Cell 74, 1135-1145.
    • (1993) Cell , vol.74 , pp. 1135-1145
    • Fu, X.Y.1    Zhang, J.J.2
  • 67
    • 0027229556 scopus 로고
    • Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras
    • Gale, N. W., Kaplan, S., Lowenstein, E. J., Schlessinger, J. and Bar-Sagi, D. (1993) Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras. Nature 363, 88-92.
    • (1993) Nature , vol.363 , pp. 88-92
    • Gale, N.W.1    Kaplan, S.2    Lowenstein, E.J.3    Schlessinger, J.4    Bar-Sagi, D.5
  • 68
    • 0029094649 scopus 로고
    • Tyrosine phosphorylation of the c-cbl proto-oncogene protein product and association with epidermal growth factor (EGF) receptor upon EGF stimulation
    • Galisteo, M. L., Dikic, I., Batzer, A. G., Langdon, W. Y. and Schlessinger, J. (1995) Tyrosine phosphorylation of the c-cbl proto-oncogene protein product and association with epidermal growth factor (EGF) receptor upon EGF stimulation. J. Biol. Chem. 270, 20242-20245.
    • (1995) J. Biol. Chem. , vol.270 , pp. 20242-20245
    • Galisteo, M.L.1    Dikic, I.2    Batzer, A.G.3    Langdon, W.Y.4    Schlessinger, J.5
  • 69
    • 0023836296 scopus 로고
    • Epidermal growth factor receptor immunoreactivity in rat brain. Development and cellular localization
    • Gómez-Pinilla, F., Knauer, D. J. and Nieto-Sampedro. M. (1988) Epidermal growth factor receptor immunoreactivity in rat brain. Development and cellular localization. Brain Res. 438, 385-390.
    • (1988) Brain Res. , vol.438 , pp. 385-390
    • Gómez-Pinilla, F.1    Knauer, D.J.2    Nieto-Sampedro, M.3
  • 70
    • 0025028911 scopus 로고
    • Microtubule-associated protein et al.Microtubule-associated protein (MAP) kinase activated by nerve growth factor and epidermal growth factor in PC12 cells
    • Gotoh, Y., Nishida, E., Yamashita, T., Kawakami, M. and Sakai, H. (1990) Microtubule-associated protein et al.Microtubule-associated protein (MAP) kinase activated by nerve growth factor and epidermal growth factor in PC12 cells. Eur. J. Biochem. 193, 661-669.
    • (1990) Eur. J. Biochem. , vol.193 , pp. 661-669
    • Gotoh, Y.1    Nishida, E.2    Yamashita, T.3    Kawakami, M.4    Sakai, H.5
  • 71
    • 0028893444 scopus 로고
    • Single-chain antibody-mediated intracellular retention of ErbB-2 impairs Neu differentiation factor and epidermal growth factor signaling
    • Graus-Porta, D., Beerli, R. R. and Hynes, N. E. (1995) Single-chain antibody-mediated intracellular retention of ErbB-2 impairs Neu differentiation factor and epidermal growth factor signaling. Mol. Cell Biol. 15, 1182-1191.
    • (1995) Mol. Cell Biol. , vol.15 , pp. 1182-1191
    • Graus-Porta, D.1    Beerli, R.R.2    Hynes, N.E.3
  • 72
    • 0020537713 scopus 로고
    • Nucleotide sequence of epidermal growth factor cDNA predicts a 128,000-molecular weight protein precursor
    • Gray, A., Dull, T. J. and Ullrich, A. (1983) Nucleotide sequence of epidermal growth factor cDNA predicts a 128,000-molecular weight protein precursor. Nature 303, 722-725.
    • (1983) Nature , vol.303 , pp. 722-725
    • Gray, A.1    Dull, T.J.2    Ullrich, A.3
  • 73
    • 0345704610 scopus 로고
    • Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor
    • Greene, L. A. and Tischler, A. S. (1976) Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc. Natl. Acad. Sci. U. S. A. 73, 2424-2428.
    • (1976) Proc. Natl. Acad. Sci. U. S. A. , vol.73 , pp. 2424-2428
    • Greene, L.A.1    Tischler, A.S.2
  • 74
    • 0016719486 scopus 로고
    • Isolation and structure of urogastrone and its relationship to epidermal growth factor
    • Gregory, H. (1975) Isolation and structure of urogastrone and its relationship to epidermal growth factor. Nature 257, 325-327.
    • (1975) Nature , vol.257 , pp. 325-327
    • Gregory, H.1
  • 75
    • 0027430339 scopus 로고
    • Mitogen-activated protein kinase regulates the epidermal growth factor receptor through activation of a tyrosine phosphatase
    • Griswold-Prenner, I., Carlin, C. R. and Rosner, M. R. (1993) Mitogen-activated protein kinase regulates the epidermal growth factor receptor through activation of a tyrosine phosphatase. J. Biol. Chem. 268, 13050-13054.
    • (1993) J. Biol. Chem. , vol.268 , pp. 13050-13054
    • Griswold-Prenner, I.1    Carlin, C.R.2    Rosner, M.R.3
  • 76
    • 0028618937 scopus 로고
    • Structure-function relationships for the EGF/TGF-α family of mitogens
    • Groenen, L. C., Nice, E. C. and Burgess, A. W. (1994) Structure-function relationships for the EGF/TGF-α family of mitogens. Growth Factors 11, 235-257.
    • (1994) Growth Factors , vol.11 , pp. 235-257
    • Groenen, L.C.1    Nice, E.C.2    Burgess, A.W.3
  • 77
    • 0020993021 scopus 로고
    • Epidermal growth factor (EGF) stimulation of cultured brain cells. II. Increased production of extracellular soluble proteins
    • Guentert-Lauber, B. and Honegger, P. (1983) Epidermal growth factor (EGF) stimulation of cultured brain cells. II. Increased production of extracellular soluble proteins. Brain Res. 313, 253-260.
    • (1983) Brain Res. , vol.313 , pp. 253-260
    • Guentert-Lauber, B.1    Honegger, P.2
  • 78
    • 0022330331 scopus 로고
    • Responsiveness of astrocytes in serum-free aggregate cultures to epidermal growth factor: Dependence on the cell cycle and the epidermal growth factor concentration
    • Guentert-Lauber, B. and Honegger, P. (1985) Responsiveness of astrocytes in serum-free aggregate cultures to epidermal growth factor: dependence on the cell cycle and the epidermal growth factor concentration. Dev. Neurosci. 7, 286-295.
    • (1985) Dev. Neurosci. , vol.7 , pp. 286-295
    • Guentert-Lauber, B.1    Honegger, P.2
  • 79
    • 0023836862 scopus 로고
    • Dissociation of c-fos from ODC expression and neuronal differentiation in a PC12 subline stably transfected with an inducible N-ras oncogene
    • Guerrero, I., Pellicer, A. and Burstein, D. E. (1988) Dissociation of c-fos from ODC expression and neuronal differentiation in a PC12 subline stably transfected with an inducible N-ras oncogene. Biochem. Biophys. Res. Commun. 150, 1185-1192.
    • (1988) Biochem. Biophys. Res. Commun. , vol.150 , pp. 1185-1192
    • Guerrero, I.1    Pellicer, A.2    Burstein, D.E.3
  • 81
    • 0025894910 scopus 로고
    • Cell transformation by the epidermal growth factor receptor and v-erbB
    • Hayman, M. J. and Enrietto, P. J. (1991) Cell transformation by the epidermal growth factor receptor and v-erbB. Cancer Cells 3, 302-307.
    • (1991) Cancer Cells , vol.3 , pp. 302-307
    • Hayman, M.J.1    Enrietto, P.J.2
  • 82
    • 0026468503 scopus 로고
    • Overexpression of the trk tyrosine kinase rapidly accelerates nerve growth factor-induced differentiation
    • Hempstead. B. L., Rabin, S. J., Kaplan, L., Reid, S., Parada, L. F. and Kaplan, D. R. (1992) Overexpression of the trk tyrosine kinase rapidly accelerates nerve growth factor-induced differentiation. Neuron 9, 883-896.
    • (1992) Neuron , vol.9 , pp. 883-896
    • Hempstead, B.L.1    Rabin, S.J.2    Kaplan, L.3    Reid, S.4    Parada, L.F.5    Kaplan, D.R.6
  • 84
    • 0025904265 scopus 로고
    • A heparin-binding growth factor secreted by macrophage-like cells that is related to EGF
    • Higashiyama, S., Abraham, J. A., Miller, J., Fiddes, J. C. and Klagsbrun, M. (1991) A heparin-binding growth factor secreted by macrophage-like cells that is related to EGF. Science 251, 936-939.
    • (1991) Science , vol.251 , pp. 936-939
    • Higashiyama, S.1    Abraham, J.A.2    Miller, J.3    Fiddes, J.C.4    Klagsbrun, M.5
  • 86
    • 0023874118 scopus 로고
    • Influence of age on epidermal growth factor receptor level in the rat brain
    • Hiramatsu, M., Kashimata, M., Sato, A., Murayama, M. and Minami, N. (1988) Influence of age on epidermal growth factor receptor level in the rat brain. Experientia 44, 23-25.
    • (1988) Experientia , vol.44 , pp. 23-25
    • Hiramatsu, M.1    Kashimata, M.2    Sato, A.3    Murayama, M.4    Minami, N.5
  • 87
    • 0030028790 scopus 로고    scopus 로고
    • A Grb2-associated docking protein in EGF- and insulin-receptor signalling
    • Holgado-Madruga, M., Emlet, D. R., Moscatello, D. K., Godwin, A. K. and Wong, A. J. (1996) A Grb2-associated docking protein in EGF- and insulin-receptor signalling. Nature 379, 560-564.
    • (1996) Nature , vol.379 , pp. 560-564
    • Holgado-Madruga, M.1    Emlet, D.R.2    Moscatello, D.K.3    Godwin, A.K.4    Wong, A.J.5
  • 89
    • 0021012919 scopus 로고
    • Epidermal growth factor (EGF) stimulation of cultured brain cells. I. Enhancement of the developmental increase in glial enzymatic activity
    • Honegger, P. and Guentert-Lauber, B. (1983) Epidermal growth factor (EGF) stimulation of cultured brain cells. I. Enhancement of the developmental increase in glial enzymatic activity. Brain Res. 313, 245-251.
    • (1983) Brain Res. , vol.313 , pp. 245-251
    • Honegger, P.1    Guentert-Lauber, B.2
  • 90
    • 0026537450 scopus 로고
    • Interaction of phosphatidylinositol 3-kinase-associated p85 with epidermal growth factor and platelet-derived growth factor receptors
    • Hu, P., Margolis, B., Skolnik, E. Y., Lammers, R., Ullrich, A. and Schlessinger, J. (1992) Interaction of phosphatidylinositol 3-kinase-associated p85 with epidermal growth factor and platelet-derived growth factor receptors. Mol. Cell Biol. 12, 981-990.
    • (1992) Mol. Cell Biol. , vol.12 , pp. 981-990
    • Hu, P.1    Margolis, B.2    Skolnik, E.Y.3    Lammers, R.4    Ullrich, A.5    Schlessinger, J.6
  • 91
    • 0030031117 scopus 로고    scopus 로고
    • I rise and dopamine secretion in PC12 cells
    • I rise and dopamine secretion in PC12 cells. J. Neurochem. 66, 124-130.
    • (1996) J. Neurochem. , vol.66 , pp. 124-130
    • Huang, C.M.1    Kao, L.S.2
  • 92
    • 0027408753 scopus 로고
    • Plasma membrane-targeted ras GTPase-activating protein is a potent suppressor of p21ras function
    • Huang, D. C., Marshall, C. J. and Hancock, J. F. (1993) Plasma membrane-targeted ras GTPase-activating protein is a potent suppressor of p21ras function. Mol. Cell Biol. 13, 2420-2431.
    • (1993) Mol. Cell Biol. , vol.13 , pp. 2420-2431
    • Huang, D.C.1    Marshall, C.J.2    Hancock, J.F.3
  • 93
    • 0019366764 scopus 로고
    • Nerve growth factor-induced alteration in the response of PC12 pheochromocytoma cells to epidermal growth factor
    • Huff, K., End, D. and Guroff. G. (1981) Nerve growth factor-induced alteration in the response of PC12 pheochromocytoma cells to epidermal growth factor. J. Cell Biol. 88, 189-198.
    • (1981) J. Cell Biol. , vol.88 , pp. 189-198
    • Huff, K.1    End, D.2    Guroff, G.3
  • 94
    • 0028670125 scopus 로고
    • The biology of erbB-2/neu/HER-2 and its role in cancer
    • Hynes, N. E. and Stern, D. F. (1994) The biology of erbB-2/neu/HER-2 and its role in cancer. Biochem. Biophys. Acta 1198, 165-184.
    • (1994) Biochem. Biophys. Acta , vol.1198 , pp. 165-184
    • Hynes, N.E.1    Stern, D.F.2
  • 96
    • 0019124028 scopus 로고
    • Temporal and spatial patterns of Purkinje cell formation in the mouse cerebellum
    • Inouye, M. and Murakami, U. (1980) Temporal and spatial patterns of Purkinje cell formation in the mouse cerebellum. J. Comp. Neurol. 194, 499-503.
    • (1980) J. Comp. Neurol. , vol.194 , pp. 499-503
    • Inouye, M.1    Murakami, U.2
  • 97
    • 0026072047 scopus 로고
    • Epidermal growth factor and basic fibroblast growth factor promote the generation of long-term potentiation in the dentate gyrus of anaesthetized rats
    • Ishiyama, J., Saito, H. and Abe, K. (1991) Epidermal growth factor and basic fibroblast growth factor promote the generation of long-term potentiation in the dentate gyrus of anaesthetized rats. Neurosci. Res. 12, 403-411.
    • (1991) Neurosci. Res. , vol.12 , pp. 403-411
    • Ishiyama, J.1    Saito, H.2    Abe, K.3
  • 98
    • 0027564252 scopus 로고
    • Schwann cell lineage-specific neu (erbB-2) gene expression in the developing rat nervous system
    • Jin, J. J., Nikitin, A. Y. and Rajewsky, M. F. (1993) Schwann cell lineage-specific neu (erbB-2) gene expression in the developing rat nervous system. Cell Growth Differ. 4, 227-237.
    • (1993) Cell Growth Differ. , vol.4 , pp. 227-237
    • Jin, J.J.1    Nikitin, A.Y.2    Rajewsky, M.F.3
  • 99
    • 0024467003 scopus 로고
    • Human urinary epidermal growth factor: Effects of age, sex and pregnancy
    • Kasai, K., Nakamura, T., Banba, N., Ishikawa, M., Konuma, S. and Shimoda, S. (1989) Human urinary epidermal growth factor: effects of age, sex and pregnancy. Horm. Res. 31, 157-162.
    • (1989) Horm. Res. , vol.31 , pp. 157-162
    • Kasai, K.1    Nakamura, T.2    Banba, N.3    Ishikawa, M.4    Konuma, S.5    Shimoda, S.6
  • 100
    • 0027098011 scopus 로고
    • Comparison between epidermal growth factor, transforming growth factor-α and EGF receptor levels in regions of adult rat brain
    • Kaser, M. R., Lakshmanan, J. and Fisher, D. A. (1992) Comparison between epidermal growth factor, transforming growth factor-α and EGF receptor levels in regions of adult rat brain. Brain Res. Mol. Brain Res. 16, 316-322.
    • (1992) Brain Res. Mol. Brain Res. , vol.16 , pp. 316-322
    • Kaser, M.R.1    Lakshmanan, J.2    Fisher, D.A.3
  • 101
    • 0026640173 scopus 로고
    • Epidermal growth factor affects both glia and cholinergic neurons in septal cell cultures
    • Kenigsberg, R. L., Mazzoni, I. E., Collier, B. and Cuello. A. C. (1992) Epidermal growth factor affects both glia and cholinergic neurons in septal cell cultures. Neuroscience 50, 85-97.
    • (1992) Neuroscience , vol.50 , pp. 85-97
    • Kenigsberg, R.L.1    Mazzoni, I.E.2    Collier, B.3    Cuello, A.C.4
  • 102
    • 0029118196 scopus 로고
    • Identification of glial cell types involved in mediating epidermal growth factor's effects on septal cholinergic neurons
    • Kenigsberg, R. L. and Mazzoni, I. E. (1995) Identification of glial cell types involved in mediating epidermal growth factor's effects on septal cholinergic neurons. J. Neurosci. 41, 734-744.
    • (1995) J. Neurosci. , vol.41 , pp. 734-744
    • Kenigsberg, R.L.1    Mazzoni, I.E.2
  • 103
    • 0025805394 scopus 로고
    • PDGP stimulation of inositol phospholipid hydrolysis requires PLC-γ 1 phosphorylation on tyrosine residues 783 and 1254
    • Kim, H. K., Kim, J. W., Zilberstein, A., Margolis, B.. Kim, J. G., Schlessinger, J. and Rhee, S. G. (1991) PDGP stimulation of inositol phospholipid hydrolysis requires PLC-γ 1 phosphorylation on tyrosine residues 783 and 1254. Cell 65, 435-441.
    • (1991) Cell , vol.65 , pp. 435-441
    • Kim, H.K.1    Kim, J.W.2    Zilberstein, A.3    Margolis, B.4    Kim, J.G.5    Schlessinger, J.6    Rhee, S.G.7
  • 104
    • 0024023873 scopus 로고
    • Egf binding to its receptor triggers a rapid tyrosine phosphorylation of the erbB-2 protein in the mammary tumor cell line SK-BR-3
    • King, C. R., Borrello, I., Bellot, F., Comoglio, P. and Schlessinger, J. (1988) Egf binding to its receptor triggers a rapid tyrosine phosphorylation of the erbB-2 protein in the mammary tumor cell line SK-BR-3. EMBO J. 7, 1647-1651.
    • (1988) EMBO J. , vol.7 , pp. 1647-1651
    • King, C.R.1    Borrello, I.2    Bellot, F.3    Comoglio, P.4    Schlessinger, J.5
  • 105
    • 0022844017 scopus 로고
    • Effects of protein kinase C activation after epidermal growth factor binding on epidermal growth factor receptor phosphorylation
    • King, C. S. and Cooper, J. A. (1986) Effects of protein kinase C activation after epidermal growth factor binding on epidermal growth factor receptor phosphorylation. J. Biol. Chem. 261, 10073-10078.
    • (1986) J. Biol. Chem. , vol.261 , pp. 10073-10078
    • King, C.S.1    Cooper, J.A.2
  • 106
    • 0025220385 scopus 로고
    • Modification of anoxic neuronal injury by human recombinant epidermal growth factor and its possible mechanism
    • Kinoshita. A., Yamada, K., Hayakawa, T., Kataoka, K., Mushiroi, T., Kohmura, E. and Mogami, H. (1990) Modification of anoxic neuronal injury by human recombinant epidermal growth factor and its possible mechanism. J. Neurosci. Res. 25, 324-330.
    • (1990) J. Neurosci. Res. , vol.25 , pp. 324-330
    • Kinoshita, A.1    Yamada, K.2    Hayakawa, T.3    Kataoka, K.4    Mushiroi, T.5    Kohmura, E.6    Mogami, H.7
  • 107
    • 0026603817 scopus 로고
    • The C-terminal SH2 domain of p85 accounts for the high affinity and specificity of the binding of phosphatidylinositol 3-kinase to phosphorylated platelet-derived growth factor beta receptor
    • Klippel, A., Escobedo, J. A., Fantl, W. J. and Williams, L. T. (1992) The C-terminal SH2 domain of p85 accounts for the high affinity and specificity of the binding of phosphatidylinositol 3-kinase to phosphorylated platelet-derived growth factor beta receptor. Mol. Cell Biol. 12, 1451-1459.
    • (1992) Mol. Cell Biol. , vol.12 , pp. 1451-1459
    • Klippel, A.1    Escobedo, J.A.2    Fantl, W.J.3    Williams, L.T.4
  • 108
    • 0023465512 scopus 로고
    • Stage- and tissue-specific expression of the neu oncogene in rat development
    • Kokai, Y., Cohen, J. A., Drebin, J. A. and Greene, M. I. (1987) Stage- and tissue-specific expression of the neu oncogene in rat development. Proc. Natl. Acad. Sci. U. S. A. 84, 8498-8501.
    • (1987) Proc. Natl. Acad. Sci. U. S. A. , vol.84 , pp. 8498-8501
    • Kokai, Y.1    Cohen, J.A.2    Drebin, J.A.3    Greene, M.I.4
  • 109
    • 0024423074 scopus 로고
    • Is breast-milk epidermal growth factor biologically active in the suckling?
    • Koldovsky, O. (1989) Is breast-milk epidermal growth factor biologically active in the suckling?. Nutrition. 5, 223-225.
    • (1989) Nutrition. , vol.5 , pp. 223-225
    • Koldovsky, O.1
  • 110
    • 0025252438 scopus 로고
    • Epidermal growth factor and basic fibroblast growth factor: Effects on an overlapping population of neocortical neurons in vitro
    • Kornblum, H. I., Raymon, H. K., Morrison, R. S., Cavanaugh, K. P., Bradshaw, R. A. and Leslie, F. M. (1990) Epidermal growth factor and basic fibroblast growth factor: effects on an overlapping population of neocortical neurons in vitro. Brain Res. 535, 255-263.
    • (1990) Brain Res. , vol.535 , pp. 255-263
    • Kornblum, H.I.1    Raymon, H.K.2    Morrison, R.S.3    Cavanaugh, K.P.4    Bradshaw, R.A.5    Leslie, F.M.6
  • 111
    • 0028891927 scopus 로고
    • A subpopulation of striatal GABAergic neurons expresses the epidermal growth factor receptor
    • Kornblum, H. I., Gall, C. M., Seroogy, K. B. and Lauterborn, J. C. (1995) A subpopulation of striatal GABAergic neurons expresses the epidermal growth factor receptor. Neuroscience 69, 1025-1029.
    • (1995) Neuroscience , vol.69 , pp. 1025-1029
    • Kornblum, H.I.1    Gall, C.M.2    Seroogy, K.B.3    Lauterborn, J.C.4
  • 112
    • 0024326947 scopus 로고
    • Isolation and characterization of ERBB3. A third member of the ERBB/epidermal growth factor receptor family: Evidence for overexpression in a subset of human mammary tumors
    • Kraus, M. H., Issing, W., Miki, T., Popescu. N. C. and Aaronson, S. A. (1989) Isolation and characterization of ERBB3. a third member of the ERBB/epidermal growth factor receptor family: evidence for overexpression in a subset of human mammary tumors. Proc. Natl. Acad. Sci. U. S. A. 86, 9193-9197.
    • (1989) Proc. Natl. Acad. Sci. U. S. A. , vol.86 , pp. 9193-9197
    • Kraus, M.H.1    Issing, W.2    Miki, T.3    Popescu, N.C.4    Aaronson, S.A.5
  • 113
    • 0024521445 scopus 로고
    • Transforming growth factor-α in the mammalian brain. Immunohistochemical detection in neurons and characterization of its mRNA
    • Kudlow, J. E., Leung, A. W., Kobrin, M. S., Paterson, A. J. and Asa. S. L. (1989) Transforming growth factor-α in the mammalian brain. Immunohistochemical detection in neurons and characterization of its mRNA. J. Biol. Chem. 264, 3880-3883.
    • (1989) J. Biol. Chem. , vol.264 , pp. 3880-3883
    • Kudlow, J.E.1    Leung, A.W.2    Kobrin, M.S.3    Paterson, A.J.4    Asa, S.L.5
  • 114
    • 0029762883 scopus 로고    scopus 로고
    • Enhanced degradation of EGF receptors by a sorting nexin, SNX1
    • Kurten, R. C., Cadena, D. L. and Gill, G. N. (1996) Enhanced degradation of EGF receptors by a sorting nexin, SNX1. Science 272, 1008-1010.
    • (1996) Science , vol.272 , pp. 1008-1010
    • Kurten, R.C.1    Cadena, D.L.2    Gill, G.N.3
  • 115
    • 0025606471 scopus 로고
    • High oxygen atmosphere for neuronal cell culture with nerve growth factor. I. Primary culture of basal forebrain cholinergic neurons from fetal and postnatal rats
    • Kushima, Y., Tsukui, H., Enokido, Y., Nishio, C. and Hatanaka, H. (1990) High oxygen atmosphere for neuronal cell culture with nerve growth factor. I. Primary culture of basal forebrain cholinergic neurons from fetal and postnatal rats. Brain Res. 536, 16-22.
    • (1990) Brain Res. , vol.536 , pp. 16-22
    • Kushima, Y.1    Tsukui, H.2    Enokido, Y.3    Nishio, C.4    Hatanaka, H.5
  • 116
    • 0022542042 scopus 로고
    • Epidermal growth factor in synaptosomal fractions of mouse cerebral cortex
    • Lakshmanan, J., Weichsel, M. E. Jr. and Fisher, D. A. (1986) Epidermal growth factor in synaptosomal fractions of mouse cerebral cortex. J. Neurochem. 46, 1081-1085.
    • (1986) J. Neurochem. , vol.46 , pp. 1081-1085
    • Lakshmanan, J.1    Weichsel M.E., Jr.2    Fisher, D.A.3
  • 117
    • 0028950805 scopus 로고
    • Recruitment of epidermal growth factor receptors into coated pits requires their activated tyrosine kinase
    • Lamaze, C. and Schmid, S. L. (1995) Recruitment of epidermal growth factor receptors into coated pits requires their activated tyrosine kinase. J. Cell Biol. 129, 47-54.
    • (1995) J. Cell Biol. , vol.129 , pp. 47-54
    • Lamaze, C.1    Schmid, S.L.2
  • 118
    • 0026569026 scopus 로고
    • Regional distribution and developmental expression of epidermal growth factor and transforming growth factor-α mRNA in mouse brain by a quantitative nuclease protection assay
    • Lazar, L. M. and Blum, M. (1992) Regional distribution and developmental expression of epidermal growth factor and transforming growth factor-α mRNA in mouse brain by a quantitative nuclease protection assay. J. Neurosci. 12, 1688-1697.
    • (1992) J. Neurosci. , vol.12 , pp. 1688-1697
    • Lazar, L.M.1    Blum, M.2
  • 119
    • 0027432407 scopus 로고
    • Activation of the SH2-containing phosphotyrosine phosphatase SH-PTP2 by its binding site, phosphotyrosine 1009, on the human platelet-derived growth factor receptor
    • Lechleider, R. J., Sugimoto, S., Bennett, A. M., Kashishian, A. S., Cooper, J. A., Shoelson, S. E., Walsh, C. T. and Neel, B. G. (1993) Activation of the SH2-containing phosphotyrosine phosphatase SH-PTP2 by its binding site, phosphotyrosine 1009, on the human platelet-derived growth factor receptor. J. Biol. Chem. 268, 21478-21481.
    • (1993) J. Biol. Chem. , vol.268 , pp. 21478-21481
    • Lechleider, R.J.1    Sugimoto, S.2    Bennett, A.M.3    Kashishian, A.S.4    Cooper, J.A.5    Shoelson, S.E.6    Walsh, C.T.7    Neel, B.G.8
  • 120
    • 0025273452 scopus 로고
    • Nck, a melanoma cDNA encoding a cytoplasmic protein consisting of the src homology units SH2 and SH3
    • Lehmann, J. M., Riethmuller, G. and Johnson, J. P. (1990) Nck, a melanoma cDNA encoding a cytoplasmic protein consisting of the src homology units SH2 and SH3. Nucleic Acids Res. 18, 1048.
    • (1990) Nucleic Acids Res. , vol.18 , pp. 1048
    • Lehmann, J.M.1    Riethmuller, G.2    Johnson, J.P.3
  • 121
    • 0028104202 scopus 로고
    • Regulation of signal transduction and signal diversity by receptor oligomerization
    • Lemmon, M. A. and Schlessinger, J. (1994) Regulation of signal transduction and signal diversity by receptor oligomerization. Trends. Biochem. Sci. 19, 459-463.
    • (1994) Trends. Biochem. Sci. , vol.19 , pp. 459-463
    • Lemmon, M.A.1    Schlessinger, J.2
  • 122
    • 0019793049 scopus 로고
    • Epidermal growth factor stimulates DNA-synthesis of astrocytes in primary cerebellar cultures
    • Leutz, A. and Schachner, M. (1981) Epidermal growth factor stimulates DNA-synthesis of astrocytes in primary cerebellar cultures. Cell Tissue Res. 220, 393-404.
    • (1981) Cell Tissue Res. , vol.220 , pp. 393-404
    • Leutz, A.1    Schachner, M.2
  • 123
    • 0019973552 scopus 로고
    • Cell type-specificity of epidermal growth factor (EGF) binding in primary cultures of early postnatal mouse cerebellum
    • Leutz, A. and Schachner, M. (1982) Cell type-specificity of epidermal growth factor (EGF) binding in primary cultures of early postnatal mouse cerebellum. Neurosci. Lett. 30, 179-182.
    • (1982) Neurosci. Lett. , vol.30 , pp. 179-182
    • Leutz, A.1    Schachner, M.2
  • 124
    • 0027312272 scopus 로고
    • Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling
    • Li, N., Batzer, A., Daly, R., Yajnik, V., Skolnik, E., Chardin, P., Bar-Sagi, D., Margolis, B. and Schlessinger. J. (1993) Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling. Nature 363, 85-88.
    • (1993) Nature , vol.363 , pp. 85-88
    • Li, N.1    Batzer, A.2    Daly, R.3    Yajnik, V.4    Skolnik, E.5    Chardin, P.6    Bar-Sagi, D.7    Margolis, B.8    Schlessinger, J.9
  • 125
    • 0026452004 scopus 로고
    • The SH2 and SH3 domain-containing Nck protein is oncogenic and a common target for phosphorylation by different surface receptors
    • Li, W., Hu, P., Skolnik. E. Y., Ullrich, A. and Schlessinger, J. (1992) The SH2 and SH3 domain-containing Nck protein is oncogenic and a common target for phosphorylation by different surface receptors. Mol. Cell Biol. 12, 5824-5833.
    • (1992) Mol. Cell Biol. , vol.12 , pp. 5824-5833
    • Li, W.1    Hu, P.2    Skolnik, E.Y.3    Ullrich, A.4    Schlessinger, J.5
  • 127
    • 0022474869 scopus 로고
    • Protein kinase C phosphorylation at Thr 654 of the unoccupied EGF receptor and EGF binding regulate functional receptor loss by independent mechanisms
    • Lin, C. R., Chen, W. S., Lazar, C. S., Carpenter, C. D., Gill, G. N., Evans, R. M. and Rosenfeld, M. G. (1986) Protein kinase C phosphorylation at Thr 654 of the unoccupied EGF receptor and EGF binding regulate functional receptor loss by independent mechanisms. Cell 44, 839-848.
    • (1986) Cell , vol.44 , pp. 839-848
    • Lin, C.R.1    Chen, W.S.2    Lazar, C.S.3    Carpenter, C.D.4    Gill, G.N.5    Evans, R.M.6    Rosenfeld, M.G.7
  • 128
    • 0026325282 scopus 로고
    • The epidermal growth factor receptor phosphorylates GTPase-activating protein (GAP) at Tyr-460, adjacent to the GAP SH2 domains
    • Liu, X. Q. and Pawson, T. (1991) The epidermal growth factor receptor phosphorylates GTPase-activating protein (GAP) at Tyr-460, adjacent to the GAP SH2 domains. Mol. Cell Biol. 11, 2511-2516.
    • (1991) Mol. Cell Biol. , vol.11 , pp. 2511-2516
    • Liu, X.Q.1    Pawson, T.2
  • 129
    • 0021803083 scopus 로고
    • The Drosophila EGF receptor gene homolog: Conservation of both hormone binding and kinase domains
    • Livneh, E., Glazer, L., Segal, D., Schlessinger, J. and Shilo, B. Z. (1985) The Drosophila EGF receptor gene homolog: conservation of both hormone binding and kinase domains. Cell 40, 599-607.
    • (1985) Cell , vol.40 , pp. 599-607
    • Livneh, E.1    Glazer, L.2    Segal, D.3    Schlessinger, J.4    Shilo, B.Z.5
  • 131
    • 0027537295 scopus 로고
    • Peptide growth factor control of olfactory neurogenesis and neuron survival in vitro: Roles of EGF and TGF-β s
    • Mahanthappa. N. K. and Schwarting, G. A. (1993) Peptide growth factor control of olfactory neurogenesis and neuron survival in vitro: roles of EGF and TGF-β s. Neuron 10, 293-305.
    • (1993) Neuron , vol.10 , pp. 293-305
    • Mahanthappa, N.K.1    Schwarting, G.A.2
  • 132
    • 0027263738 scopus 로고
    • Peptide growth factors protect against ischemia in culture by preventing nitric oxide toxicity
    • Maiese, K., Boniece, I., DeMeo, D. and Wagner, J. A. (1993) Peptide growth factors protect against ischemia in culture by preventing nitric oxide toxicity. J. Neurosci. 13, 3034-3040.
    • (1993) J. Neurosci. , vol.13 , pp. 3034-3040
    • Maiese, K.1    Boniece, I.2    DeMeo, D.3    Wagner, J.A.4
  • 133
    • 0024240294 scopus 로고
    • C-erbB and the epidermal growth-factor receptor: A molecule with dual identity
    • Maihle, N. J. and Kung, H. J. (1989) C-erbB and the epidermal growth-factor receptor: a molecule with dual identity. Biochim. Biophys. Acta 948, 287-304.
    • (1989) Biochim. Biophys. Acta , vol.948 , pp. 287-304
    • Maihle, N.J.1    Kung, H.J.2
  • 135
    • 0025190084 scopus 로고
    • Tyrosine kinase activity is essential for the association of phospholipase C-γ with the epidermal growth factor receptor
    • Margolis, B., Bellot, F., Honegger, A. M., Ullrich, A., Schlessinger, J. and Zilberstein, A. (1990) Tyrosine kinase activity is essential for the association of phospholipase C-γ with the epidermal growth factor receptor. Mol. Cell Biol. 10, 435-441.
    • (1990) Mol. Cell Biol. , vol.10 , pp. 435-441
    • Margolis, B.1    Bellot, F.2    Honegger, A.M.3    Ullrich, A.4    Schlessinger, J.5    Zilberstein, A.6
  • 136
    • 0020806079 scopus 로고
    • Transforming growth factors produced by retrovirus-transformed rodent fibroblasts and human melanoma cells: Amino acid sequence homology with epidermal growth factor
    • Marquardt, H., Hunkapiller, M. W., Hood, L. E., Twardzik, D. R., De Larco, J. E., Stephenson, J. R. and Todaro, G. J. (1983) Transforming growth factors produced by retrovirus-transformed rodent fibroblasts and human melanoma cells: amino acid sequence homology with epidermal growth factor. Proc. Natl. Acad. Sci. U. S. A. 80, 4684-4688.
    • (1983) Proc. Natl. Acad. Sci. U. S. A. , vol.80 , pp. 4684-4688
    • Marquardt, H.1    Hunkapiller, M.W.2    Hood, L.E.3    Twardzik, D.R.4    De Larco, J.E.5    Stephenson, J.R.6    Todaro, G.J.7
  • 137
    • 0021360015 scopus 로고
    • Rat transforming growth factor type 1: Structure and relation to epidermal growth factor
    • Marquardt, H., Hunkapiller, M. W., Hood, L. E. and Todaro, G. J. (1984) Rat transforming growth factor type 1: structure and relation to epidermal growth factor. Science 223, 1079-1082.
    • (1984) Science , vol.223 , pp. 1079-1082
    • Marquardt, H.1    Hunkapiller, M.W.2    Hood, L.E.3    Todaro, G.J.4
  • 138
    • 0028872649 scopus 로고
    • Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
    • Marshall, C. J. (1995) Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell 80, 179-185.
    • (1995) Cell , vol.80 , pp. 179-185
    • Marshall, C.J.1
  • 139
    • 0024543241 scopus 로고
    • Biological effects of epidermal growth factor, with emphasis on the gastrointestinal tract and liver: An update
    • Marti, U., Burwen. S. J. and Jones, A. L. (1989) Biological effects of epidermal growth factor, with emphasis on the gastrointestinal tract and liver: an update. Hepatology 9, 126-138.
    • (1989) Hepatology , vol.9 , pp. 126-138
    • Marti, U.1    Burwen, S.J.2    Jones, A.L.3
  • 140
    • 0026756438 scopus 로고
    • Cloning of ASH, a ubiquitous protein composed of one Src homology region (SH) 2 and two SH3 domains, from human and rat cDNA libraries
    • Matuoka, K., Shibata, M., Yamakawa, A. and Takenawa, T. (1992) Cloning of ASH, a ubiquitous protein composed of one Src homology region (SH) 2 and two SH3 domains, from human and rat cDNA libraries. Proc. Natl. Acad. Sci. U. S. A. 89, 9015-9019.
    • (1992) Proc. Natl. Acad. Sci. U. S. A. , vol.89 , pp. 9015-9019
    • Matuoka, K.1    Shibata, M.2    Yamakawa, A.3    Takenawa, T.4
  • 141
    • 0027992039 scopus 로고
    • Localization and characterization of epidermal growth-factor receptors in the developing rat medial septal area in culture
    • Mazzoni, I. E. and Kenigsberg, R. L. (1994) Localization and characterization of epidermal growth-factor receptors in the developing rat medial septal area in culture. Brain Res. 656, 115-126.
    • (1994) Brain Res. , vol.656 , pp. 115-126
    • Mazzoni, I.E.1    Kenigsberg, R.L.2
  • 142
    • 0030024755 scopus 로고    scopus 로고
    • Transforming growth factor differentially affects GABAergic and cholinergic neurons in rat medial septal cell cultures
    • Mazzoni, I. E. and Kenigsberg, R. L. (1996) Transforming growth factor differentially affects GABAergic and cholinergic neurons in rat medial septal cell cultures. Brain Res. 707, 88-99.
    • (1996) Brain Res. , vol.707 , pp. 88-99
    • Mazzoni, I.E.1    Kenigsberg, R.L.2
  • 143
    • 0024380391 scopus 로고
    • Phospholipase C-γ is a substrate for the PDGF and EGF receptor protein-tyrosine kinases in vivo and in vitro
    • Meisenhelder, J., Suh, P. G., Rhee. S. G. and Hunter, T. (1989) Phospholipase C-γ is a substrate for the PDGF and EGF receptor protein-tyrosine kinases in vivo and in vitro. Cell 57, 1109-1122.
    • (1989) Cell , vol.57 , pp. 1109-1122
    • Meisenhelder, J.1    Suh, P.G.2    Rhee, S.G.3    Hunter, T.4
  • 144
    • 0028136280 scopus 로고
    • Expression of catalytically inactive Syp phosphatase in 3T3 cells blocks stimulation of mitogen-activated protein kinase by insulin
    • Milarski, K. L. and Saltiel, A. R. (1994) Expression of catalytically inactive Syp phosphatase in 3T3 cells blocks stimulation of mitogen-activated protein kinase by insulin. J. Biol. Chem. 269, 21239-21243.
    • (1994) J. Biol. Chem. , vol.269 , pp. 21239-21243
    • Milarski, K.L.1    Saltiel, A.R.2
  • 147
    • 0009937474 scopus 로고
    • Basic fibroblast growth factor supports the survival of cerebral cortical neurons in primary culture
    • Morrison, R. S., Sharma, A., de Vellis, J. and Bradshaw, R. A. (1986) Basic fibroblast growth factor supports the survival of cerebral cortical neurons in primary culture. Proc, Natl. Acad. Sci. U. S. A. 83, 7537-7541.
    • (1986) Proc, Natl. Acad. Sci. U. S. A. , vol.83 , pp. 7537-7541
    • Morrison, R.S.1    Sharma, A.2    De Vellis, J.3    Bradshaw, R.A.4
  • 148
    • 0023617007 scopus 로고
    • Trophic stimulation of cultured neurons from neonatal rat brain by epidermal growth factor
    • Morrison, R. S., Kornblum, H. I., Leslie, F. M. and Bradshaw, R. A. (1987) Trophic stimulation of cultured neurons from neonatal rat brain by epidermal growth factor. Science 238, 72-75.
    • (1987) Science , vol.238 , pp. 72-75
    • Morrison, R.S.1    Kornblum, H.I.2    Leslie, F.M.3    Bradshaw, R.A.4
  • 149
    • 0024264753 scopus 로고
    • Basic fibroblast growth factor and epidermal growth factor exert differential trophic effects on cns neurons
    • Morrison, R. S., Keating, R. F. and Moskal, J. R. (1988) Basic fibroblast growth factor and epidermal growth factor exert differential trophic effects on CNS neurons. J. Neurosci. Res. 21, 71-79.
    • (1988) J. Neurosci. Res. , vol.21 , pp. 71-79
    • Morrison, R.S.1    Keating, R.F.2    Moskal, J.R.3
  • 150
    • 0021752840 scopus 로고
    • Induction of c-fos gene and protein by growth factors precedes activation of c-myc
    • Müller, R., Bravo, R., Burckhardt, J. and Curran, T. (1984) Induction of c-fos gene and protein by growth factors precedes activation of c-myc. Nature 312, 716-720.
    • (1984) Nature , vol.312 , pp. 716-720
    • Müller, R.1    Bravo, R.2    Burckhardt, J.3    Curran, T.4
  • 151
    • 0026604693 scopus 로고
    • Epidermal growth factor-induced survival and proliferation of neuronal precursor cells from embryonic rat mesencephalon
    • Mytilineou, C., Park, T. H. and Shen, J. (1992) Epidermal growth factor-induced survival and proliferation of neuronal precursor cells from embryonic rat mesencephalon. Neurosci. Lett. 135, 62-66.
    • (1992) Neurosci. Lett. , vol.135 , pp. 62-66
    • Mytilineou, C.1    Park, T.H.2    Shen, J.3
  • 152
    • 0027506999 scopus 로고
    • Epidermal growth factor and transforming growth factor- can induce neuronal differentiation of rat pheochromocytoma PC12 cells under particular culture conditions
    • Nakafuku, M. and Kaziro, Y. (1993) Epidermal growth factor and transforming growth factor-can induce neuronal differentiation of rat pheochromocytoma PC12 cells under particular culture conditions. FEBS Lett. 315, 227-232.
    • (1993) FEBS Lett. , vol.315 , pp. 227-232
    • Nakafuku, M.1    Kaziro, Y.2
  • 153
    • 0027535742 scopus 로고
    • Activation of the ζ isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate
    • Nakanishi, H., Brewer, K. A. and Exton, J. H. (1993) Activation of the ζ isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate. J. Biol. Chem. 268, 13-16.
    • (1993) J. Biol. Chem. , vol.268 , pp. 13-16
    • Nakanishi, H.1    Brewer, K.A.2    Exton, J.H.3
  • 154
    • 0028969610 scopus 로고
    • Association of epidermal growth factor receptors with coated pit adaptins via a tyrosine phosphorylation-regulated mechanism
    • Nesterov, A., Kurten. R. C. and Gill, G. N. (1995) Association of epidermal growth factor receptors with coated pit adaptins via a tyrosine phosphorylation-regulated mechanism. J. Biol. Chem. 270, 6320-6327.
    • (1995) J. Biol. Chem. , vol.270 , pp. 6320-6327
    • Nesterov, A.1    Kurten, R.C.2    Gill, G.N.3
  • 155
    • 0023730586 scopus 로고
    • Epidermal growth factor receptor immunoreactivity in rat brain astrocytes. Response to injury
    • Nieto-Sampedro, M., Gómez-Pinilla, F., Knauer, D. J. and Broderick, J. T. (1988) Epidermal growth factor receptor immunoreactivity in rat brain astrocytes. Response to injury. Neurosci. Lett. 91, 276-282.
    • (1988) Neurosci. Lett. , vol.91 , pp. 276-282
    • Nieto-Sampedro, M.1    Gómez-Pinilla, F.2    Knauer, D.J.3    Broderick, J.T.4
  • 156
    • 0027410497 scopus 로고
    • The MAP kinase cascade is essential for diverse signal transduction pathways
    • Nishida, E. and Gotoh, Y. (1993) The MAP kinase cascade is essential for diverse signal transduction pathways. Trends. Biochem. Sci. 18, 128-131.
    • (1993) Trends. Biochem. Sci. , vol.18 , pp. 128-131
    • Nishida, E.1    Gotoh, Y.2
  • 157
    • 0026451081 scopus 로고
    • Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C
    • Nishizuka, Y. (1992) Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science 258. 607-614.
    • (1992) Science , vol.258 , pp. 607-614
    • Nishizuka, Y.1
  • 158
    • 0027374486 scopus 로고
    • Identification of Trk binding sites for SHC and phosphatidylinositol 3′-kinase and formation of a multimeric signaling complex
    • Obermeier, A., Lammers, R., Wiesmuller, K. H., Jung, G.. Schlessinger, J. and Ullrich. A. (1993) Identification of Trk binding sites for SHC and phosphatidylinositol 3′-kinase and formation of a multimeric signaling complex. J. Biol. Chem. 268, 22963-22966.
    • (1993) J. Biol. Chem. , vol.268 , pp. 22963-22966
    • Obermeier, A.1    Lammers, R.2    Wiesmuller, K.H.3    Jung, G.4    Schlessinger, J.5    Ullrich, A.6
  • 159
    • 0028916337 scopus 로고
    • Endocytosis and lysosomal targeting of epidermal growth factor receptors are mediated by distinct sequences independent of the tyrosine kinase domain
    • Opresko, L. K., Chang, C. P., Will, B. H., Burke, P. M., Gill, G. N. and Wiley, H. S. (1995) Endocytosis and lysosomal targeting of epidermal growth factor receptors are mediated by distinct sequences independent of the tyrosine kinase domain. J. Biol. Chem. 270, 4325-4333.
    • (1995) J. Biol. Chem. , vol.270 , pp. 4325-4333
    • Opresko, L.K.1    Chang, C.P.2    Will, B.H.3    Burke, P.M.4    Gill, G.N.5    Wiley, H.S.6
  • 161
    • 0027081071 scopus 로고
    • Protection from 1-methyl-4-phenylpyridinium (MPP + ) toxicity and stimulation of regrowth of MPP( + )-damaged dopaminergic fibers by treatment of mesencephalic cultures with EGF and basic FGF
    • Park, T. H. and Mytilineou, C. (1992) Protection from 1-methyl-4-phenylpyridinium (MPP + ) toxicity and stimulation of regrowth of MPP( + )-damaged dopaminergic fibers by treatment of mesencephalic cultures with EGF and basic FGF. Brain Res. 599, 83-97.
    • (1992) Brain Res. , vol.599 , pp. 83-97
    • Park, T.H.1    Mytilineou, C.2
  • 162
    • 0028859279 scopus 로고
    • Protein modules and signalling networks
    • Pawson, T. (1995) Protein modules and signalling networks. Nature 373, 573-580.
    • (1995) Nature , vol.373 , pp. 573-580
    • Pawson, T.1
  • 163
    • 0026776424 scopus 로고
    • Isolation of the neu/HER-2 stimulatory ligand: A 44 kd glycoprotein that induces differentiation of mammary tumor cells
    • Peles. E., Bacus, S. S., Koski, R. A., Lu, H. S., Wen, D., Ogden, S. G., Levy, R. B. and Yarden, Y. (1992) Isolation of the neu/HER-2 stimulatory ligand: a 44 kd glycoprotein that induces differentiation of mammary tumor cells. Cell 69, 205-216.
    • (1992) Cell , vol.69 , pp. 205-216
    • Peles, E.1    Bacus, S.S.2    Koski, R.A.3    Lu, H.S.4    Wen, D.5    Ogden, S.G.6    Levy, R.B.7    Yarden, Y.8
  • 164
    • 0027465159 scopus 로고
    • Cell-type specific interaction of Neu differentiation factor (NDF/heregulin) with Neu/HER-2 suggests complex ligand-receptor relationships
    • Peles, E., Ben-Levy, R., Tzahar, E., Liu, N., Wen, D. and Yarden, Y. (1993) Cell-type specific interaction of Neu differentiation factor (NDF/heregulin) with Neu/HER-2 suggests complex ligand-receptor relationships. EMBO J. 12, 961-971.
    • (1993) EMBO J. , vol.12 , pp. 961-971
    • Peles, E.1    Ben-Levy, R.2    Tzahar, E.3    Liu, N.4    Wen, D.5    Yarden, Y.6
  • 166
    • 0025997294 scopus 로고
    • Intraventricular infusion of epidermal growth factor restores dopaminergic pathway in hemiparkinsoman rats
    • Pezzoli, G., Zecchinelli, A., Ricciardi. S., Burke, R. E., Fahn, S., Scarlato, G. and Carenzi, A. (1991) Intraventricular infusion of epidermal growth factor restores dopaminergic pathway in hemiparkinsoman rats. Mov. Disord. 6, 281-287.
    • (1991) Mov. Disord. , vol.6 , pp. 281-287
    • Pezzoli, G.1    Zecchinelli, A.2    Ricciardi, S.3    Burke, R.E.4    Fahn, S.5    Scarlato, G.6    Carenzi, A.7
  • 168
    • 0025884379 scopus 로고
    • Epidermal growth factor and the nervous system
    • Plata-Salamán, C. R. (1991) Epidermal growth factor and the nervous system. Peptides 12, 653-663.
    • (1991) Peptides , vol.12 , pp. 653-663
    • Plata-Salamán, C.R.1
  • 169
    • 0025266694 scopus 로고
    • The amphiregulin gene encodes a novel epidermal growth factor-related protein with tumor-inhibitory activity
    • Plowman, G. D., Green, J. M., McDonald, V. L., Neubauer, M. G., Disteche, C. M., Todaro, G. J. and Shoyab. M. (1990a) The amphiregulin gene encodes a novel epidermal growth factor-related protein with tumor-inhibitory activity. Mol. Cell Biol. 10, 1969-1981.
    • (1990) Mol. Cell Biol. , vol.10 , pp. 1969-1981
    • Plowman, G.D.1    Green, J.M.2    McDonald, V.L.3    Neubauer, M.G.4    Disteche, C.M.5    Todaro, G.J.6    Shoyab, M.7
  • 173
    • 0026733002 scopus 로고
    • PC12 cell neuronal differentiation is associated with prolonged p21ras activity and consequent prolonged ERK activity
    • Qui, M. S. and Green, S. H. (1992) PC12 cell neuronal differentiation is associated with prolonged p21ras activity and consequent prolonged ERK activity. Neuron 9, 705-717.
    • (1992) Neuron , vol.9 , pp. 705-717
    • Qui, M.S.1    Green, S.H.2
  • 174
    • 0023877172 scopus 로고
    • Visualization of growth factor receptor sites in rat forebrain
    • Quirion, R.. Araujo, D., Nair, N. P. and Chabot, J. G. (1988) Visualization of growth factor receptor sites in rat forebrain. Synapse 2, 212-218.
    • (1988) Synapse , vol.2 , pp. 212-218
    • Quirion, R.1    Araujo, D.2    Nair, N.P.3    Chabot, J.G.4
  • 175
    • 0027395119 scopus 로고
    • SNT, a differentiation-specific target of neurotrophic factor-induced tyrosine kinase activity in neurons and PC12 cells
    • Rabin, S. J.. Cleghon, V. and Kaplan, D. R. (1993) SNT, a differentiation-specific target of neurotrophic factor-induced tyrosine kinase activity in neurons and PC12 cells. Mol. Cell Biol. 13, 2203-2213.
    • (1993) Mol. Cell Biol. , vol.13 , pp. 2203-2213
    • Rabin, S.J.1    Cleghon, V.2    Kaplan, D.R.3
  • 176
    • 0026666371 scopus 로고
    • Activation of phosphatidylinositol 3-kinase by epidermal growth factor, basic fibroblast growth factor, and nerve growth factor in PC12 pheochromocytoma cells
    • Raffioni, S. and Bradshaw, R. A. (1992) Activation of phosphatidylinositol 3-kinase by epidermal growth factor, basic fibroblast growth factor, and nerve growth factor in PC12 pheochromocytoma cells. Proc. Natl. Acad. Sci. U. S. A. 89, 9121-9125.
    • (1992) Proc. Natl. Acad. Sci. U. S. A. , vol.89 , pp. 9121-9125
    • Raffioni, S.1    Bradshaw, R.A.2
  • 178
    • 0026526516 scopus 로고
    • A multipotent EGF-responsive striatal embryonic progenitor cell produces neurons and astrocytes
    • Reynolds. B. A., Tetzlaff, W. and Weiss, S. (1992) A multipotent EGF-responsive striatal embryonic progenitor cell produces neurons and astrocytes. J. Neurosci. 12, 4565-4574.
    • (1992) J. Neurosci. , vol.12 , pp. 4565-4574
    • Reynolds, B.A.1    Tetzlaff, W.2    Weiss, S.3
  • 179
    • 0024403320 scopus 로고
    • Studies of inositol phospholipid-specific phospholipase C
    • Rhee, S. G., Suh, P. G., Ryu, S. H. and Lee, S. Y. (1989) Studies of inositol phospholipid-specific phospholipase C. Science 244, 546-550.
    • (1989) Science , vol.244 , pp. 546-550
    • Rhee, S.G.1    Suh, P.G.2    Ryu, S.H.3    Lee, S.Y.4
  • 180
    • 0030032998 scopus 로고    scopus 로고
    • Stimulation of growth factor receptor signal transduction by activation of voltage-sensitive calcium channels
    • Rosen, L. B. and Greenberg, M. E. (1996) Stimulation of growth factor receptor signal transduction by activation of voltage-sensitive calcium channels. Proc. Natl. Acad. Sci. USA 93, 1113-1118.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 1113-1118
    • Rosen, L.B.1    Greenberg, M.E.2
  • 181
    • 0027294981 scopus 로고
    • The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1
    • Rozakis-Adcock, M., Fernley, R., Wade, J., Pawson, T. and Bowtell, D. (1993) The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1. Nature 363, 83-85.
    • (1993) Nature , vol.363 , pp. 83-85
    • Rozakis-Adcock, M.1    Fernley, R.2    Wade, J.3    Pawson, T.4    Bowtell, D.5
  • 182
    • 0027385186 scopus 로고
    • Induction by EGF and interferon- of tyrosine phosphorylated DNA binding proteins in mouse liver nuclei
    • Ruff-Jamison, S., Chen, K. and Cohen, S. (1993) Induction by EGF and interferon-of tyrosine phosphorylated DNA binding proteins in mouse liver nuclei. Science 261, 1733-1736.
    • (1993) Science , vol.261 , pp. 1733-1736
    • Ruff-Jamison, S.1    Chen, K.2    Cohen, S.3
  • 184
    • 0027496114 scopus 로고
    • A common nuclear signal transduclion pathway activated by growth factor and cytokine receptors
    • Sadowski, H. B., Shuai, K., Darnell, J. E. Jr. and Gilman, M. Z. (1993) A common nuclear signal transduclion pathway activated by growth factor and cytokine receptors. Science 261, 1739-1744.
    • (1993) Science , vol.261 , pp. 1739-1744
    • Sadowski, H.B.1    Shuai, K.2    Darnell J.E., Jr.3    Gilman, M.Z.4
  • 185
    • 0029157414 scopus 로고
    • Epidermal growth factor (EGF), transforming growth factor-α (TGF-α), and basic fibroblast growth factor (bFGF) differentially influence neural precursor cells of mouse embryonic mesencephalon
    • Santa-Olalla, J. and Covarrubias, L. (1995) Epidermal growth factor (EGF), transforming growth factor-α (TGF-α), and basic fibroblast growth factor (bFGF) differentially influence neural precursor cells of mouse embryonic mesencephalon. J. Neurosci. Res. 42, 172-183.
    • (1995) J. Neurosci. Res. , vol.42 , pp. 172-183
    • Santa-Olalla, J.1    Covarrubias, L.2
  • 186
    • 0015502174 scopus 로고
    • The primary structure of epidermal growth factor
    • Savage, C. R. Jr., Inagami, T. and Cohen, S. (1972) The primary structure of epidermal growth factor. J. Biol. Chem. 247, 7612-7621.
    • (1972) J. Biol. Chem. , vol.247 , pp. 7612-7621
    • Savage C.R., Jr.1    Inagami, T.2    Cohen, S.3
  • 187
    • 0015758018 scopus 로고
    • Epidermal growth factor. Location of disulfide bonds
    • Savage, C. R. Jr., Hash, J. H. and Cohen, S. (1973) Epidermal growth factor. Location of disulfide bonds. J. Biol. Chem. 248, 7669-7672.
    • (1973) J. Biol. Chem. , vol.248 , pp. 7669-7672
    • Savage C.R., Jr.1    Hash, J.H.2    Cohen, S.3
  • 188
    • 0024400631 scopus 로고
    • Epidermal growth factor immunoreactive material in the rat brain. Localization and identification of multiple species
    • Schaudies, R. P., Christian, E. L. and Savage, C. R. Jr. (1989) Epidermal growth factor immunoreactive material in the rat brain. Localization and identification of multiple species. J. Biol. Chem. 264, 10447-10450.
    • (1989) J. Biol. Chem. , vol.264 , pp. 10447-10450
    • Schaudies, R.P.1    Christian, E.L.2    Savage C.R., Jr.3
  • 189
    • 0027279176 scopus 로고
    • How receptor tyrosine kinases activate ras
    • Schlessinger, J. (1993) How receptor tyrosine kinases activate Ras. Trends. Biochem. Sci. 18, 273-275.
    • (1993) Trends. Biochem. Sci. , vol.18 , pp. 273-275
    • Schlessinger, J.1
  • 191
    • 0026793456 scopus 로고
    • Growth factor signaling by receptor tyrosine kinases
    • Schlessinger, J. and Ullrich, A. (1992) Growth factor signaling by receptor tyrosine kinases. Neuron 9, 383-391.
    • (1992) Neuron , vol.9 , pp. 383-391
    • Schlessinger, J.1    Ullrich, A.2
  • 192
    • 0020620305 scopus 로고
    • Structure of a mouse submaxillary messenger RNA encoding epidermal growth factor and seven related proteins
    • Scott, J., Urdea, M., Quiroga, M., Sanchez-Pescador, R., Fong, N., Selby, M., Rutter, W. J. and Bell, G. I. (1983) Structure of a mouse submaxillary messenger RNA encoding epidermal growth factor and seven related proteins. Science 221, 236-240.
    • (1983) Science , vol.221 , pp. 236-240
    • Scott, J.1    Urdea, M.2    Quiroga, M.3    Sanchez-Pescador, R.4    Fong, N.5    Selby, M.6    Rutter, W.J.7    Bell, G.I.8
  • 193
    • 0027174238 scopus 로고
    • Cellular localization of transforming growth factor-alpha mRNA in rat forebrain
    • Seroogy, K. B., Lundgren, K. H., Lee, D. C., Guthrie, K. M. and Gall, C. M. (1993) Cellular localization of transforming growth factor-alpha mRNA in rat forebrain. J. Neurochem. 60, 1777-1782.
    • (1993) J. Neurochem. , vol.60 , pp. 1777-1782
    • Seroogy, K.B.1    Lundgren, K.H.2    Lee, D.C.3    Guthrie, K.M.4    Gall, C.M.5
  • 194
    • 0028814611 scopus 로고
    • Proliferate zones of postnatal rat brain express epidermal growth factor receptor mRNA
    • Seroogy, K. B., Gall, C. M., Lee, D. C. and Kornblum, H. I. (1995) Proliferate zones of postnatal rat brain express epidermal growth factor receptor mRNA. Brain Res. 670, 157-164.
    • (1995) Brain Res. , vol.670 , pp. 157-164
    • Seroogy, K.B.1    Gall, C.M.2    Lee, D.C.3    Kornblum, H.I.4
  • 196
    • 0000276099 scopus 로고
    • Amphiregulin: A bifunctional growth-modulating glycoprotein produced by the phorbol 12-myristate 13-acetate-treated human breast adenocarcinoma cell line MCF-7
    • Shoyab, M., McDonald, V. L.. Bradley, J. G. and Todaro, G. J. (1988) Amphiregulin: a bifunctional growth-modulating glycoprotein produced by the phorbol 12-myristate 13-acetate-treated human breast adenocarcinoma cell line MCF-7. Proc. Natl. Acad. Sci. U. S. A. 85, 6528-6532.
    • (1988) Proc. Natl. Acad. Sci. U. S. A. , vol.85 , pp. 6528-6532
    • Shoyab, M.1    McDonald, V.L.2    Bradley, J.G.3    Todaro, G.J.4
  • 197
    • 0024593476 scopus 로고
    • Structure and function of human amphiregulin: A member of the epidermal growth factor family
    • Shoyab, M., Plowman, G. D., McDonald, V. L., Bradley, J. G. and Todaro, G. J. (1989) Structure and function of human amphiregulin: a member of the epidermal growth factor family. Science 243, 1074-1076.
    • (1989) Science , vol.243 , pp. 1074-1076
    • Shoyab, M.1    Plowman, G.D.2    McDonald, V.L.3    Bradley, J.G.4    Todaro, G.J.5
  • 198
    • 0027772891 scopus 로고
    • Polypeptide signalling to the nucleus through tyrosine phosphorylation of Jak and Stat proteins
    • Shuai, K., Ziemiecki, A., Wilks, A. F., Harpur, A. G.. Sadowski, H. B., Gilman, M. Z. and Darnell, J. E. (1993) Polypeptide signalling to the nucleus through tyrosine phosphorylation of Jak and Stat proteins. Nature 366, 580-583.
    • (1993) Nature , vol.366 , pp. 580-583
    • Shuai, K.1    Ziemiecki, A.2    Wilks, A.F.3    Harpur, A.G.4    Sadowski, H.B.5    Gilman, M.Z.6    Darnell, J.E.7
  • 199
    • 0020464118 scopus 로고
    • Epidermal growth factor binding and mitogenic activity on purified populations of cells from the central nervous system
    • Simpson, D. L.. Morrison, R., de Vellis, J. and Herschman. H. R. (1982) Epidermal growth factor binding and mitogenic activity on purified populations of cells from the central nervous system. J. Neurosci. Res. 8, 453-462.
    • (1982) J. Neurosci. Res. , vol.8 , pp. 453-462
    • Simpson, D.L.1    Morrison, R.2    De Vellis, J.3    Herschman, H.R.4
  • 200
    • 0025921611 scopus 로고
    • Cloning of P13 kinase-associated p85 utilizing a novel method for expression/cloning of target proteins for receptor tyrosine kinases
    • Skolnik, E. Y., Margolis, B., Mohammadi, M., Lowenstein, E., Fischer, R., Drepps, A., Ullrich, A. and Schlessinger, J. (1991) Cloning of P13 kinase-associated p85 utilizing a novel method for expression/cloning of target proteins for receptor tyrosine kinases. Cell 65, 83-90.
    • (1991) Cell , vol.65 , pp. 83-90
    • Skolnik, E.Y.1    Margolis, B.2    Mohammadi, M.3    Lowenstein, E.4    Fischer, R.5    Drepps, A.6    Ullrich, A.7    Schlessinger, J.8
  • 202
    • 0022517005 scopus 로고
    • Biosynthesis and metabolic degradation of receptors for epidermal growth factor
    • Soderquist, A. M. and Carpenter, G. (1986) Biosynthesis and metabolic degradation of receptors for epidermal growth factor. J. Membr. Biol. 90, 97-105.
    • (1986) J. Membr. Biol. , vol.90 , pp. 97-105
    • Soderquist, A.M.1    Carpenter, G.2
  • 203
    • 0026802515 scopus 로고
    • Nerve growth factor promotes the activation of phosphatidylinositol 3-kinase and its association with the trk tyrosine kinase
    • Soltoff, S. P., Rabin, S. L., Cantley, L. C. and Kaplan, D. R. (1992) Nerve growth factor promotes the activation of phosphatidylinositol 3-kinase and its association with the trk tyrosine kinase. J. Biol. Chem. 267, 17472-17477.
    • (1992) J. Biol. Chem. , vol.267 , pp. 17472-17477
    • Soltoff, S.P.1    Rabin, S.L.2    Cantley, L.C.3    Kaplan, D.R.4
  • 204
    • 0028302018 scopus 로고
    • ErbB3 is involved in activation of phosphatidylinositol 3-kinase by epidermal growth factor
    • Soltoff, S. P., Carraway, K. L., Prigent, S. A., Gullick, W. G. and Cantley, L. C. (1994) ErbB3 is involved in activation of phosphatidylinositol 3-kinase by epidermal growth factor. Mol. Cell Biol. 14, 3550-3558.
    • (1994) Mol. Cell Biol. , vol.14 , pp. 3550-3558
    • Soltoff, S.P.1    Carraway, K.L.2    Prigent, S.A.3    Gullick, W.G.4    Cantley, L.C.5
  • 205
    • 0029671427 scopus 로고    scopus 로고
    • cbl is a cytosolic adapter protein that associates with phosphoinositide 3-kinase in response to epidermal growth factor in PC12 and other cells
    • cbl is a cytosolic adapter protein that associates with phosphoinositide 3-kinase in response to epidermal growth factor in PC12 and other cells. J. Biol. Chem. 271, 563-567.
    • (1996) J. Biol. Chem. , vol.271 , pp. 563-567
    • Soltoff, S.P.1    Cantley, L.C.2
  • 206
    • 0028944988 scopus 로고
    • Stoichiometric interaction of the epidermal growth factor receptor with the clathrin-associated protein complex AP-2
    • Sorkin, A., McKinsey, T., Shih, W., Kirchhausen, T. and Carpenter, G. (1995) Stoichiometric interaction of the epidermal growth factor receptor with the clathrin-associated protein complex AP-2. J. Biol. Chem. 270, 619-625.
    • (1995) J. Biol. Chem. , vol.270 , pp. 619-625
    • Sorkin, A.1    McKinsey, T.2    Shih, W.3    Kirchhausen, T.4    Carpenter, G.5
  • 207
    • 0027249993 scopus 로고
    • Interaction of activated EGF receptors with coated pit adaptins
    • Sorkin, A. and Carpenter, G. (1993) Interaction of activated EGF receptors with coated pit adaptins. Science 261, 612-615.
    • (1993) Science , vol.261 , pp. 612-615
    • Sorkin, A.1    Carpenter, G.2
  • 208
    • 0027620152 scopus 로고
    • Endocytosís of growth factor receptors
    • Sorkin, A. and Waters, C. M. (1993) Endocytosís of growth factor receptors. Bioessays 15, 375-382.
    • (1993) Bioessays , vol.15 , pp. 375-382
    • Sorkin, A.1    Waters, C.M.2
  • 209
    • 0028149381 scopus 로고
    • The coordinated action of protein tyrosine phosphatases and kinases in cell signaling
    • Sun, H. and Tonks, N. K. (1994) The coordinated action of protein tyrosine phosphatases and kinases in cell signaling. Trends. Biochem. Sci. 19, 480-485.
    • (1994) Trends. Biochem. Sci. , vol.19 , pp. 480-485
    • Sun, H.1    Tonks, N.K.2
  • 210
    • 0015523701 scopus 로고
    • Epidermal growth factor. Physical and chemical properties
    • Taylor, J. M., Mitchell, W. M. and Cohen, S. (1972) Epidermal growth factor. Physical and chemical properties. J. Biol. Chem. 247, 5928-5934.
    • (1972) J. Biol. Chem. , vol.247 , pp. 5928-5934
    • Taylor, J.M.1    Mitchell, W.M.2    Cohen, S.3
  • 211
    • 0024560780 scopus 로고
    • Influence of epidermal growth factor on long-term potentiation in the hippocampal slice
    • Terlau, H. and Seifert, W. (1989) Influence of epidermal growth factor on long-term potentiation in the hippocampal slice. Brain Res. 484, 352-356.
    • (1989) Brain Res. , vol.484 , pp. 352-356
    • Terlau, H.1    Seifert, W.2
  • 212
    • 0017097271 scopus 로고
    • Transformation by murine and feline sarcoma viruses specifically blocks binding of epidermal growth factor to cells
    • Todaro, G. J. and DeLarco, J. E. (1976) Transformation by murine and feline sarcoma viruses specifically blocks binding of epidermal growth factor to cells. Nature 264, 26-31.
    • (1976) Nature , vol.264 , pp. 26-31
    • Todaro, G.J.1    DeLarco, J.E.2
  • 215
    • 0026486878 scopus 로고
    • Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor
    • Traverse, S., Gomez, N., Paterson, H., Marshall, C. and Cohen, P. (1992) Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor. Biochem. J. 288, 351-355.
    • (1992) Biochem. J. , vol.288 , pp. 351-355
    • Traverse, S.1    Gomez, N.2    Paterson, H.3    Marshall, C.4    Cohen, P.5
  • 216
    • 0028483678 scopus 로고
    • EGF triggers neuronal differentiation of PC12 cells that overexpress the EGF receptor
    • Traverse, S., Seedorf, K., Paterson, H., Marshall, C. J., Cohen, P. and Ullrich, A. (1994) EGF triggers neuronal differentiation of PC12 cells that overexpress the EGF receptor. Curr. Biol. 4, 694-701.
    • (1994) Curr. Biol. , vol.4 , pp. 694-701
    • Traverse, S.1    Seedorf, K.2    Paterson, H.3    Marshall, C.J.4    Cohen, P.5    Ullrich, A.6
  • 217
    • 0028084337 scopus 로고
    • Ternary complex factors: Growth factor regulated transcriptional activators
    • Treisman, R. (1994) Ternary complex factors: growth factor regulated transcriptional activators. Curr. Opin. Genet. Dev. 4, 96-101.
    • (1994) Curr. Opin. Genet. Dev. , vol.4 , pp. 96-101
    • Treisman, R.1
  • 219
    • 0028170817 scopus 로고
    • Receptor protein-tyrosine kinases and their signal transduction pathways
    • van der Geer, P., Hunter, T. and Lindberg, R. A. (1994) Receptor protein-tyrosine kinases and their signal transduction pathways. Annu. Rev. Cell Biol. 10, 251-337.
    • (1994) Annu. Rev. Cell Biol. , vol.10 , pp. 251-337
    • Van Der Geer, P.1    Hunter, T.2    Lindberg, R.A.3
  • 221
    • 0023881864 scopus 로고
    • Neurotrophic effects of basic and acidic fibroblast growth factors are not mediated through glial cells
    • Walicke, P. A. and Baird, A. (1988) Neurotrophic effects of basic and acidic fibroblast growth factors are not mediated through glial cells. Brain Res. 468, 71-79.
    • (1988) Brain Res. , vol.468 , pp. 71-79
    • Walicke, P.A.1    Baird, A.2
  • 223
    • 0023869453 scopus 로고
    • Localization of immunoreactive epidermal growth factor receptors in human nervous system
    • Werner, M. H., Nanney, L. B., Stoscheck, C. M. and King, L. E. (1988) Localization of immunoreactive epidermal growth factor receptors in human nervous system. J. Histochem. Cytochem. 36, 81-86.
    • (1988) J. Histochem. Cytochem. , vol.36 , pp. 81-86
    • Werner, M.H.1    Nanney, L.B.2    Stoscheck, C.M.3    King, L.E.4
  • 224
    • 0017261153 scopus 로고
    • Density dependent proliferation of human glia cells stimulated by epidermal growth factor
    • Westermark, B. (1976) Density dependent proliferation of human glia cells stimulated by epidermal growth factor. Biochem. Biophys. Res. Commun. 69, 304-310.
    • (1976) Biochem. Biophys. Res. Commun. , vol.69 , pp. 304-310
    • Westermark, B.1
  • 225
    • 0023429079 scopus 로고
    • Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification
    • Wong, A. J., Bigner, S. H., Bigner, D. D., Kinzler. K. W.. Hamilton, S. R. and Vogelstein, B. (1987) Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification. Proc. Natl. Acad. Sci. U. S. A. 84, 6899-6903.
    • (1987) Proc. Natl. Acad. Sci. U. S. A. , vol.84 , pp. 6899-6903
    • Wong, A.J.1    Bigner, S.H.2    Bigner, D.D.3    Kinzler, K.W.4    Hamilton, S.R.5    Vogelstein, B.6
  • 226
    • 0027164311 scopus 로고
    • The cytoplasmic raf oncogene induces a neuronal phenotype in PC12 cells: A potential role for cellular raf kinases in neuronal growth factor signal transduction
    • Wood, K. W., Qi, H., D'Arcangelo, G., Armstrong, R. C., Roberts, T. M. and Halegoua, S. (1993) The cytoplasmic raf oncogene induces a neuronal phenotype in PC12 cells: a potential role for cellular raf kinases in neuronal growth factor signal transduction. Proc. Natl. Acad. Sci. U. S. A. 90, 5016-5020.
    • (1993) Proc. Natl. Acad. Sci. U. S. A. , vol.90 , pp. 5016-5020
    • Wood, K.W.1    Qi, H.2    D'Arcangelo, G.3    Armstrong, R.C.4    Roberts, T.M.5    Halegoua, S.6
  • 229
    • 0029143471 scopus 로고
    • Epidermal growth factor prevents oxygen-triggered apoptosis and induces sustained signalling in cultured rat cerebral cortical neurons
    • Yamada, M., Enokido, Y., Ikeuchi, T. and Hatanaka, H. (1995) Epidermal growth factor prevents oxygen-triggered apoptosis and induces sustained signalling in cultured rat cerebral cortical neurons. Eur. J. Neurosci. 7, 2130-2138.
    • (1995) Eur. J. Neurosci. , vol.7 , pp. 2130-2138
    • Yamada, M.1    Enokido, Y.2    Ikeuchi, T.3    Hatanaka, H.4
  • 230
    • 0030019789 scopus 로고    scopus 로고
    • PC12h-R cell, a subclone of PC12 cells, shows EGF-induced neuronal differentiation and sustained signaling
    • Yamada. M., Ikeuchi, T., Aimoto, S. and Hatanaka, H. (1996a) PC12h-R cell, a subclone of PC12 cells, shows EGF-induced neuronal differentiation and sustained signaling. J. Neurosci. Res. 43, 355-364.
    • (1996) J. Neurosci. Res. , vol.43 , pp. 355-364
    • Yamada, M.1    Ikeuchi, T.2    Aimoto, S.3    Hatanaka, H.4
  • 231
    • 0029833639 scopus 로고    scopus 로고
    • EGF-induced sustained tyrosine phosphorylation and decreased rate of down-regulation of EGF receptor in PC12h-R cells which show neuronal differentiation in response to EGF
    • Yamada. M., Ikeuchi, T., Aimoto, S. and Hatanaka, H. (1996b) EGF-induced sustained tyrosine phosphorylation and decreased rate of down-regulation of EGF receptor in PC12h-R cells which show neuronal differentiation in response to EGF. Neurochem. Res. 21, 821-828.
    • (1996) Neurochem. Res. , vol.21 , pp. 821-828
    • Yamada, M.1    Ikeuchi, T.2    Aimoto, S.3    Hatanaka, H.4
  • 232
    • 0028963084 scopus 로고
    • Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor
    • Yao, R. and Cooper, G. M. (1995) Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor. Science 267, 2003-2006.
    • (1995) Science , vol.267 , pp. 2003-2006
    • Yao, R.1    Cooper, G.M.2
  • 233
    • 0028353684 scopus 로고
    • Septal neuron cholinergic and GABAergic functions: Differential regulation by basic fibroblast growth factor and epidermal growth factor
    • Yokoyama, M.. Morrison, R. S., Black, I. B. and Dreyfus, C. F. (1994) Septal neuron cholinergic and GABAergic functions: differential regulation by basic fibroblast growth factor and epidermal growth factor. Dev. Brain Res. 78, 201-209.
    • (1994) Dev. Brain Res. , vol.78 , pp. 201-209
    • Yokoyama, M.1    Morrison, R.S.2    Black, I.B.3    Dreyfus, C.F.4
  • 235
    • 0027323844 scopus 로고
    • Dephosphorylation and inactivation of the mitogen-activated protein kinase by a mitogen-induced Thr/Tyr protein phosphatase
    • Zheng. C. F. and Guan, K. L. (1993) Dephosphorylation and inactivation of the mitogen-activated protein kinase by a mitogen-induced Thr/Tyr protein phosphatase. J. Biol. Chem. 268, 16116-16119.
    • (1993) J. Biol. Chem. , vol.268 , pp. 16116-16119
    • Zheng, C.F.1    Guan, K.L.2
  • 236
    • 0028349735 scopus 로고
    • Stat3: A STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6
    • Zhong, Z., Wen, Z. and Darnell, J. E. Jr. (1994) Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6. Science 264, 95-98.
    • (1994) Science , vol.264 , pp. 95-98
    • Zhong, Z.1    Wen, Z.2    Darnell J.E., Jr.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.