Amitriptyline-mediated cognitive enhancement in aged 3×Tg Alzheimer's disease mice is associated with neurogenesis and neurotrophic activity

PLoS ONE

Volumn 6, Issue 6, 2011, Pages

  Chadwick, Wayne ^a   Mitchell, Nick ^a   Caroll, Jenna ^b   Zhou, Yu ^a   Park, Sung Soo ^a   Wang, Liyun ^a   Becker, Kevin G ^a   Zhang, Yongqing ^a   Lehrmann, Elin ^a   Wood III, William H ^a   Martin, Bronwen ^a   Maudsley, Stuart ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMITRIPTYLINE; AMYLOID BETA PROTEIN; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; MONOMER; NEUROTROPHIC FACTOR; TAU PROTEIN; TRICYCLIC ANTIDEPRESSANT AGENT;

AGED; ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; CYTOTOXICITY; DENTATE GYRUS; HIPPOCAMPUS; LEARNING; LONG TERM MEMORY; MALE; MEMORY; MEMORY CONSOLIDATION; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SHORT TERM MEMORY; SYNAPTIC MEMBRANE; TRANSGENIC MOUSE; ANIMAL; CELL CULTURE; DRUG EFFECT; IMMUNOHISTOCHEMISTRY; METABOLISM; PATHOPHYSIOLOGY;

MUS;

ALZHEIMER DISEASE; AMITRIPTYLINE; AMYLOID BETA-PEPTIDES; ANIMALS; ANTIDEPRESSIVE AGENTS, TRICYCLIC; CELLS, CULTURED; COGNITION DISORDERS; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, TRANSGENIC; NEUROGENESIS;

EID: 79959602251     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0021660     Document Type: Article

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